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1. 发明申请

US20220099634A1 SAMPLE INTRODUCTION DEVICES AND SYSTEMS AND METHODS OF USING AND PRODUCING THEM 有权
公开(公告)号：US20220099634A1
公开(公告)日：2022-03-31
申请号：US17038841
申请日：2020-09-30
申请人： Benjamin J. Black , Robert H. Jackson, III
发明人： Benjamin J. Black , Robert H. Jackson, III
IPC分类号： G01N30/02 , H02K49/10 , G01D5/14
摘要： Magnetic couplers and sample introduction devices including them are described. In certain configurations, a sample introduction device can include a magnetic coupler that can be used to hold down a sampling device to permit introduction of an analyte sample from the sampling device to an instrument or another component. Systems including the magnetic couplers, and methods and devices to produce them are also described.

2. 发明授权

US07120998B2 Fabrication of chopper for particle beam instrument 失效
公开(公告)号：US07120998B2
公开(公告)日：2006-10-17
申请号：US10922368
申请日：2004-08-20
申请人： Nicholas LeCursi , Lawrence J. LeGore , Robert H. Jackson, III , C. Bronson H. Crothers , Peter H. Kleban , Brian G. Frederick
发明人： Nicholas LeCursi , Lawrence J. LeGore , Robert H. Jackson, III , C. Bronson H. Crothers , Peter H. Kleban , Brian G. Frederick
IPC分类号： H01R43/00
CPC分类号： G21K1/087 , G01N23/05 , H01J49/0018 , H01J49/0031 , H01J49/061 , H01J49/446 , H01L2924/0002 , Y10T29/4902 , Y10T29/49082 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , H01L2924/00
摘要： A technique for providing a grid for a gate such as utilized in gating a stream of ions or other particles in a spectrometer instrument. The grid of wires may, for example, be a so-called Bradbury-Nielson Gate that consists of a set of two electrically isolated sets of equally spaced wires that lie substantially in the same plane and alternate in potential. The method utilized to provide is to first fabricate a frame of an insulating substrate having a hole and depositing metal film patterns such that conductive portions are formed on either side of the hole. Conductive portions on either side form a series of terminating pads on the portion of the substrate closest to the hole and a bus bar. Grid wires are then formed by stretching a section of wire with desired constant tension across the hole and bonding the ends of the wire to a respective one of the pads on one side and bus bar on the other side. The method provides a rapid, inexpensive way to fabricate such modulating devices.

3. 发明授权

US09859105B2 Multiple ion gate method and apparatus 有权
公开(公告)号：US09859105B2
公开(公告)日：2018-01-02
申请号：US14742653
申请日：2015-06-17
申请人： Adam Michael Graichen , Robert H Jackson , Mark A Osgood , Ching Wu , Jianglin Wu
发明人： Adam Michael Graichen , Robert H Jackson , Mark A Osgood , Ching Wu , Jianglin Wu
IPC分类号： H01J49/00 , G01N27/62 , G01N30/72
CPC分类号： H01J49/0031 , G01N27/622 , G01N30/7233 , H01J49/004
摘要： A second gate in an Ion Mobility Spectrometer is used to select or block different time windows of the ion mobility spectrum. A second gate in the Ion Mobility Mass Spectrometer is used to modulate peak intensities in the IMS spectrum, allowing each peak in the IMS spectrum to be unambiguously matched with its set of fragment ions in a subsequent MS-MS mass spectrum.

4. 发明授权

US06781120B2 Fabrication of chopper for particle beam instrument 失效
标题翻译：粒子束仪的切碎机制造
公开(公告)号：US06781120B2
公开(公告)日：2004-08-24
申请号：US10165851
申请日：2002-06-07
申请人： Nicholas LeCursi , Lawrence J. LeGore , Robert H. Jackson, III , C. Bronson H. Crothers , Peter H. Kleban , Brian G. Frederick
发明人： Nicholas LeCursi , Lawrence J. LeGore , Robert H. Jackson, III , C. Bronson H. Crothers , Peter H. Kleban , Brian G. Frederick
IPC分类号： H01R4300
CPC分类号： G21K1/087 , G01N23/05 , H01J49/0018 , H01J49/0031 , H01J49/061 , H01J49/446 , H01L2924/0002 , Y10T29/4902 , Y10T29/49082 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , H01L2924/00
摘要： A technique for providing a grid for a gate such as utilized in gating a stream of ions or other particles in a spectrometer instrument. The grid of wires may, for example, be a so-called Bradbury-Nielson Gate that consists of a set of two electrically isolated sets of equally spaced wires that lie substantially in the same plane and alternate in potential. The method utilized to provide is to first fabricate a frame of an insulating substrate having a hole and depositing metal film patterns such that conductive portions are formed on either side of the hole. Conductive portions on either side form a series of terminating pads on the portion of the substrate closest to the hole and a bus bar. Grid wires are then formed by stretching a section of wire with desired constant tension across the hole and bonding the ends of the wire to a respective one of the pads on one side and bus bar on the other side. The method provides a rapid, inexpensive way to fabricate such modulating devices.
摘要翻译：提供用于门的栅格的技术，例如用于在光谱仪器中门控离子或其他颗粒物流。电线的网格可以是例如所谓的Bradbury-Nielson门，其由两组基本上位于同一平面中且交替潜在的等间隔的导线的两组电隔离组合组成。用于提供的方法是首先制造具有孔的绝缘基板的框架并沉积金属膜图案，使得导电部分形成在孔的任一侧上。任一侧上的导电部分形成在最靠近该孔的基板部分上的一系列端接焊盘和汇流条。然后通过将所需的恒定张力的一段导线拉伸穿过该孔并且将导线的端部粘合到另一侧的一侧上的焊盘和另一侧的母线上而形成网格线。该方法提供了制造这种调制装置的快速，便宜的方式。

5. 发明申请

US20160005581A1 MULTIPLE ION GATE METHOD AND APPARATUS 审中-公开
标题翻译：多个门控方法和装置
公开(公告)号：US20160005581A1
公开(公告)日：2016-01-07
申请号：US14742653
申请日：2015-06-17
申请人： Adam Michael Graichen , Robert H. Jackson , Mark A. Osgood , Ching Wu , Jianglin Wu
发明人： Adam Michael Graichen , Robert H. Jackson , Mark A. Osgood , Ching Wu , Jianglin Wu
IPC分类号： H01J49/06 , H01J49/00 , G01N27/62
CPC分类号： H01J49/0031 , G01N27/622 , G01N30/7233 , H01J49/004
摘要： A second gate in an Ion Mobility Spectrometer is used to select or block different time windows of the ion mobility spectrum. A second gate in the Ion Mobility Mass Spectrometer is used to modulate peak intensities in the IMS spectrum, allowing each peak in the IMS spectrum to be unambiguously matched with its set of fragment ions in a subsequent MS-MS mass spectrum.
摘要翻译：离子移动光谱仪中的第二个门用于选择或阻止离子迁移谱的不同时间窗。离子迁移质谱仪中的第二个栅极用于调制IMS光谱中的峰值强度，允许IMS光谱中的每个峰与其随后的MS-MS质谱中的碎片离子组明确匹配。

6. 发明授权

US07569835B2 Gating grid and method of manufacture 失效
标题翻译：门格栅和制造方法
公开(公告)号：US07569835B2
公开(公告)日：2009-08-04
申请号：US11714691
申请日：2007-03-06
申请人： Brian G. Frederick , Lawrence J. LeGore , Rosemary Smith , Scott Collins , Robert H. Jackson, III
发明人： Brian G. Frederick , Lawrence J. LeGore , Rosemary Smith , Scott Collins , Robert H. Jackson, III
IPC分类号： H01J29/52 , H01J37/063 , G01D59/44 , H01J49/00
CPC分类号： H01J49/061 , Y10S438/927 , Y10S438/977 , Y10T29/49046 , Y10T29/49117
摘要： The present invention relates generally to grids for gating a stream of charged particles and methods for manufacturing the same. In one embodiment, the present invention relates to a Bradbury-Nielson gate having transmission line grid elements. In one embodiment is a feed structure for a gating grid where a drive source is coupled to a feeding transmission line with the same geometry as the chopper and continues with the same geometry to a termination transmission line. Also included is a method for fabricating a gate for charged particles which includes micromachining at least two gate elements from at least one wafer, wherein each gate element includes at least one grid element; metalizing the grid elements; and assembling the gate elements such that the grid elements of the gate elements are interleaved, thereby forming a Bradbury Nielson gate.
摘要翻译：本发明一般涉及用于选通带电粒子流的栅格及其制造方法。在一个实施例中，本发明涉及具有传输线网格元件的Bradbury-Nielson门。在一个实施例中是用于门控格栅的馈送结构，其中驱动源耦合到与斩波器具有相同几何形状的馈电传输线，并且以相同的几何形状连续地连接到终端传输线。还包括一种用于制造带电粒子的栅极的方法，其包括从至少一个晶片微加工至少两个栅极元件，其中每个栅极元件包括至少一个栅格元件; 金属化网格元素; 以及组装门元件，使得门元件的栅格元件交错，从而形成Bradbury Nielson门。

7. 发明授权

US06592395B2 In-line cable connector assembly 失效
标题翻译：在线电缆连接器组件
公开(公告)号：US06592395B2
公开(公告)日：2003-07-15
申请号：US09969826
申请日：2001-10-03
申请人： Reed Scott Brown , Robert H. Jackson , Ronald Kohl , Don Terry , Perry K. White , Ronald L. Wild
发明人： Reed Scott Brown , Robert H. Jackson , Ronald Kohl , Don Terry , Perry K. White , Ronald L. Wild
IPC分类号： H01R424
CPC分类号： H01R4/2429 , H01R13/6477 , Y10S439/941
摘要： A connector assembly for connecting wire leads of a first cable to corresponding wire leads of a second cable. A terminal housing structure has a first base, and a second base facing opposite to the first base. First pairs of connector terminals are configured to connect with pairs of wire leads of the first cable, and second pairs of connector terminals are configured to connect with pairs of wire leads of the second cable. A wiring board captured between the first and second bases has sets of conductive terminal openings at corresponding locations in the board. The first pairs of connector terminals are mounted on one side of the board in first pairs of terminal openings, and the second pairs of connector terminals are mounted on the opposite side of the board in second pairs of terminal openings which are electrically connected to the first pair of openings. The sets of terminal openings are spaced apart sufficiently to avoid cross-talk between the pairs of connector terminals.
摘要翻译：一种用于将第一电缆的引线连接到第二电缆的相应电线引线的连接器组件。端子壳体结构具有第一基座和与第一基座相对的第二基座。第一对连接器端子被配置为与第一电缆的一对导线连接，并且第二对连接器端子被配置为与第二电缆的成对的导线连接。捕获在第一和第二基座之间的布线板在板的相应位置处具有一组导电端子开口。第一对连接器端子安装在第一对端子开口中的板的一侧上，并且第二对连接器端子安装在第二对端子开口的第二对端子开口的相对侧上，该端子开口电连接到第一对一对开口。这些端子开口的间隔足以避免连接器端子对之间的串扰。

8. 发明授权

US07403867B2 Spectroscopy instrument using broadband modulation and statistical estimation techniques to account for component artifacts 失效
标题翻译：光谱仪使用宽带调制和统计估计技术来解决组件工件
公开(公告)号：US07403867B2
公开(公告)日：2008-07-22
申请号：US11386503
申请日：2006-03-22
申请人： Lawrence J. LeGore , Robert H. Jackson, III , Zhong Yu Yang , Linda K. DeNoyer , Peter H. Kleban , Brian G. Frederick
发明人： Lawrence J. LeGore , Robert H. Jackson, III , Zhong Yu Yang , Linda K. DeNoyer , Peter H. Kleban , Brian G. Frederick
IPC分类号： G06F19/00 , G01B9/00
CPC分类号： G21K1/087 , G01N23/05 , H01J49/0018 , H01J49/0031 , H01J49/061 , H01J49/446 , H01L2924/0002 , Y10T29/4902 , Y10T29/49082 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , H01L2924/00
摘要： A spectroscopy instrument that uses spectra produced from random binary sequence modulated data. Statistical estimation techniques are used to achieve resolution enhancement, while properly accounting for the Poisson noise distribution and other artifacts introduced by a modulator or “chopper” or other system components. A resolution similar to that of modern spectrometers can be achieved. Both static and dynamic behaviors are theoretically or measured experimentally accounted for in the model as determined. In one embodiment, the finite penetration of the field beyond the plane of the chopper leads to non-ideal chopper response, which is characterized in terms of an “energy corruption” effect and a lead or lag in the time at which the beam responds to the chopper potential.
摘要翻译：使用从随机二进制序列调制数据产生的光谱的光谱仪器。统计估计技术用于实现分辨率增强，同时适当地考虑由调制器或“斩波器”或其他系统组件引入的泊松噪声分布和其他伪像。可以实现与现代光谱仪相似的分辨率。静态和动态行为在理论上或实验中都经过实验确定。在一个实施例中，场强超过斩波器平面的有限穿透导致非理想的斩波器响应，其特征在于“能量损耗”效应和波束响应时间的引导或滞后砍刀潜力。

9. 发明授权

US07031877B2 Spectroscopy instrument using broadband modulation and statistical estimation techniques to account for component artifacts 失效
标题翻译：光谱仪使用宽带调制和统计估计技术来解决组件工件
公开(公告)号：US07031877B2
公开(公告)日：2006-04-18
申请号：US10924282
申请日：2004-08-23
申请人： Lawrence J. LeGore , Robert H. Jackson, III , Zhong Yu Yang , Linda K. DeNoyer , Peter H. Kleban , Brian G. Frederick
发明人： Lawrence J. LeGore , Robert H. Jackson, III , Zhong Yu Yang , Linda K. DeNoyer , Peter H. Kleban , Brian G. Frederick
IPC分类号： G06F19/00 , G01B9/00
CPC分类号： G21K1/087 , G01N23/05 , H01J49/0018 , H01J49/0031 , H01J49/061 , H01J49/446 , H01L2924/0002 , Y10T29/4902 , Y10T29/49082 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , H01L2924/00
摘要： A spectroscopy instrument that uses spectra produced from random binary sequence modulated data. Statistical estimation techniques are used to achieve resolution enhancement, while properly accounting for the Poisson noise distribution and other artifacts introduced by a modulator or “chopper” or other system components. Indeed, a resolution similar to that of modern spectrometers can be achieved with a dramatic performance advantage over conventional, serial detection analyzers. Both static and dynamic behaviors are theoretically or measured experimentally accounted for in the model as determined. In one embodiment, the finite penetration of the field beyond the plane of the chopper leads to non-ideal chopper response, which is characterized in terms of an “energy corruption” effect and a lead or lag in the time at which the beam responds to the chopper potential.
摘要翻译：使用从随机二进制序列调制数据产生的光谱的光谱仪器。统计估计技术用于实现分辨率增强，同时适当地考虑由调制器或“斩波器”或其他系统组件引入的泊松噪声分布和其他伪像。实际上，与传统的串行检测分析仪相比，可以实现与现代光谱仪类似的分辨率，具有显着的性能优势。静态和动态行为在理论上或实验中都经过实验确定。在一个实施例中，场强超过斩波器平面的有限穿透导致非理想的斩波器响应，其特征在于“能量损耗”效应和波束响应时间的引导或滞后砍刀潜力。

10. 发明授权

US06782342B2 Spectroscopy instrument using broadband modulation and statistical estimation techniques to account for component artifacts 失效
标题翻译：光谱仪使用宽带调制和统计估计技术来解决组件工件
公开(公告)号：US06782342B2
公开(公告)日：2004-08-24
申请号：US10165852
申请日：2002-06-07
申请人： Lawrence J. LeGore , Robert H. Jackson, III , Zhong Yu Yang , Linda K. DeNoyer , Peter H. Kleban , Brian G. Frederick
发明人： Lawrence J. LeGore , Robert H. Jackson, III , Zhong Yu Yang , Linda K. DeNoyer , Peter H. Kleban , Brian G. Frederick
IPC分类号： G06F1900
CPC分类号： G21K1/087 , G01N23/05 , H01J49/0018 , H01J49/0031 , H01J49/061 , H01J49/446 , H01L2924/0002 , Y10T29/4902 , Y10T29/49082 , Y10T29/49117 , Y10T29/49155 , Y10T29/49156 , H01L2924/00
摘要： A spectroscopy instrument that uses spectra produced from random binary sequence modulated data. Statistical estimation techniques are used to achieve resolution enhancement, while properly accounting for the Poisson noise distribution and other artifacts introduced by a modulator or “chopper” or other system components. Indeed, a resolution similar to that of modern spectrometers can be achieved with a dramatic performance advantage over conventional, serial detection analyzers. Both static and dynamic behaviors are theoretically or measured experimentally accounted for in the model as determined. In one embodiment, the finite penetration of the field beyond the plane of the chopper leads to non-ideal chopper response, which is characterized in terms of an “energy corruption” effect and a lead or lag in the time at which the beam responds to the chopper potential.
摘要翻译：使用从随机二进制序列调制数据产生的光谱的光谱仪器。统计估计技术用于实现分辨率增强，同时适当地考虑由调制器或“斩波器”或其他系统组件引入的泊松噪声分布和其他伪像。实际上，与传统的串行检测分析仪相比，可以实现与现代光谱仪类似的分辨率，具有显着的性能优势。静态和动态行为在理论上或实验中都经过实验确定。在一个实施例中，场强超过斩波器平面的有限穿透导致非理想的斩波器响应，其特征在于“能量损耗”效应和波束响应时间的引导或滞后砍刀潜力。

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