专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20050176718A1 Aza- and polyaza-naphthalenyl carboxamides useful as HIV integrase inhibitors 审中-公开
公开(公告)号：US20050176718A1
公开(公告)日：2005-08-11
申请号：US11056412
申请日：2005-02-11
申请人： Neville Anthony , Robert Gomez , Steven Young , Melissa Egbertson , John Wai , Linghang Zhuang , Mark Embrey , Lekhanh Tran , Jeffrey Melamed , H. Langford , James Guare , Thorsten Fisher , Samson Jolly , Michelle Kuo , Debra Perlow , Jennifer Bennett , Timothy Funk
发明人： Neville Anthony , Robert Gomez , Steven Young , Melissa Egbertson , John Wai , Linghang Zhuang , Mark Embrey , Lekhanh Tran , Jeffrey Melamed , H. Langford , James Guare , Thorsten Fisher , Samson Jolly , Michelle Kuo , Debra Perlow , Jennifer Bennett , Timothy Funk
IPC分类号： A61K31/4375 , A61K31/47 , A61K31/4985 , A61K31/541 , A61K31/554 , A61P31/12 , A61P31/18 , C07D20060101 , C07D215/48 , C07D221/00 , C07D241/00 , C07D471/00 , C07D471/04 , C07D471/16 , C07D487/00 , C07D519/00 , A61K31/498 , A61K31/4745 , C07D471/02 , C07D487/02
CPC分类号： C07D471/04
摘要： Aza- and polyaza-naphthalenyl carboxamide derivatives including certain quinoline carboxamide and naphthyridine carboxamide derivatives are described. These compounds are inhibitors of HIV integrase and inhibitors of HIV replication, and are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, as compounds or pharmaceutically acceptable salts, or as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of preventing, treating or delaying the onset of AIDS and methods of preventing or treating infection by HIV are also described.

2. 发明授权

US08404856B2 Non-nucleoside reverse transcriptase inhibitors 有权
标题翻译：非核苷逆转录酶抑制剂
公开(公告)号：US08404856B2
公开(公告)日：2013-03-26
申请号：US12742159
申请日：2008-11-14
申请人： Thomas J. Tucker , Robert Tynebor , John T. Sisko , Neville Anthony , Robert Gomez , Samson M. Jolly
发明人： Thomas J. Tucker , Robert Tynebor , John T. Sisko , Neville Anthony , Robert Gomez , Samson M. Jolly
IPC分类号： C07D403/00 , C07D401/00
CPC分类号： C07D401/06 , C07D471/04
摘要： Heteroaromatic compounds of Formula (I) are HIV reverse transcriptase inhibitors, wherein ring A is: (ii-a), (ii-b), (ii-c), (ii-d), or (ii-e); and wherein n, L, M, U, X, Y, Z, RE, RF, R1, R2A, R2B, R2C, R3, R8, R9 and R10 are defined herein. The compounds of Formula I and their pharmaceutically acceptable salts and prodrugs are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts and prodrugs can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
摘要翻译：式（I）的杂芳族化合物是HIV逆转录酶抑制剂，其中环A是：（ii-a），（ii-b），（ii-c），（ii-d）或（ii-e）; 并且其中n，L，M，U，X，Y，Z，RE，RF，R1，R2A，R2B，R2C，R3，R8，R9和R10在本文中定义。式I化合物及其药学上可接受的盐和前药可用于抑制HIV逆转录酶，预防和治疗HIV感染以及预防，延缓发病或进展以及AIDS治疗。化合物及其盐和前药可以用作药物组合物中的成分，任选与其它抗病毒剂，免疫调节剂，抗生素或疫苗组合使用。

3. 发明申请

US20060247229A1 Sulfonyl substituted n-(biarylmethyl) aminocyclopropanecarboxamides 失效
标题翻译：磺酰基取代的正（联芳基甲基）氨基环丙烷甲酰胺
公开(公告)号：US20060247229A1
公开(公告)日：2006-11-02
申请号：US10565040
申请日：2004-08-03
申请人： Neville Anthony , Robert Gomez , Samson Jolly , John Lim , Dai-shi Su
发明人： Neville Anthony , Robert Gomez , Samson Jolly , John Lim , Dai-shi Su
IPC分类号： A61K31/54 , A61K31/505 , A61K31/18
CPC分类号： C07D213/82 , C07C307/02 , C07C309/65 , C07C309/66 , C07C309/67 , C07C309/76 , C07C311/09 , C07C311/46 , C07C2601/02 , C07D215/58 , C07D239/28 , C07D417/12
摘要： N-(Sulfonyloxybiarylmethyl)aminocyclopropanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
摘要翻译： N-（磺酰氧基联芳基甲基）氨基环丙烷甲酰胺衍生物是缓激肽B1拮抗剂或反激动剂，其可用于治疗或预防与缓激肽B1途径相关的疼痛和炎症等症状。

4. 发明申请

US20100286192A1 NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS 审中-公开
标题翻译：非核苷酸逆转录酶抑制剂
公开(公告)号：US20100286192A1
公开(公告)日：2010-11-11
申请号：US12839807
申请日：2010-07-20
申请人： Neville J. Anthony , Robert Gomez
发明人： Neville J. Anthony , Robert Gomez
IPC分类号： A61K31/437 , A61K31/4709 , A61P31/18
CPC分类号： C07D471/04 , C07D231/54 , C07D249/18
摘要： Compounds of Formula I: are HIV reverse transcriptase inhibitors, wherein V, W, X, Y, Z, R1, R2, R4, R5, R6, ring A, ring B, j and k are defined herein. The compounds of Formula I, and the pharmaceutically acceptable salts and prodrugs thereof, are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
摘要翻译：式I化合物是HIV逆转录酶抑制剂，其中V，W，X，Y，Z，R 1，R 2，R 4，R 5，R 6，环A，环B，j和k如本文所定义。式I化合物及其药学上可接受的盐和前药可用于抑制HIV逆转录酶，预防和治疗HIV感染以及预防，延缓发病或进展以及AIDS治疗。化合物及其盐可以用作药物组合物中的成分，任选与其它抗病毒剂，免疫调节剂，抗生素或疫苗组合使用。

5. 发明授权

US07781454B2 Non-nucleoside reverse transcriptase inhibitors 有权
标题翻译：非核苷逆转录酶抑制剂
公开(公告)号：US07781454B2
公开(公告)日：2010-08-24
申请号：US11999686
申请日：2007-12-06
申请人： Neville J. Anthony , Robert Gomez
发明人： Neville J. Anthony , Robert Gomez
IPC分类号： A01N43/42 , A61K31/44 , A61K31/415 , C07D471/02 , C07D491/02 , C07D498/02 , C07D213/56
CPC分类号： C07D471/04 , C07D231/54 , C07D249/18
摘要： Compounds of Formula I: are HIV reverse transcriptase inhibitors, wherein V, W, X, Y, Z, R1, R2, R4, R5, R6, ring A, ring B, j and k are defined herein. The compounds of Formula I, and the pharmaceutically acceptable salts and prodrugs thereof, are useful in the inhibition of HIV reverse transcriptase, the prophylaxis and treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antivirals, immunomodulators, antibiotics or vaccines.
摘要翻译：式I化合物是HIV逆转录酶抑制剂，其中V，W，X，Y，Z，R 1，R 2，R 4，R 5，R 6，环A，环B，j和k如本文所定义。式I化合物及其药学上可接受的盐和前药可用于抑制HIV逆转录酶，预防和治疗HIV感染以及预防，延缓发病或进展以及AIDS治疗。化合物及其盐可以用作药物组合物中的成分，任选与其它抗病毒剂，免疫调节剂，抗生素或疫苗组合使用。

6. 发明授权

US07332499B2 Sulfonyl substituted n-(biarylmethyl) aminocyclopropanecarboxamides 失效
标题翻译：磺酰基取代的正（联芳基甲基）氨基环丙烷甲酰胺
公开(公告)号：US07332499B2
公开(公告)日：2008-02-19
申请号：US10565040
申请日：2004-08-03
申请人： Neville J. Anthony , Robert Gomez , Samson M. Jolly , John Jin Lim , Dai-shi Su
发明人： Neville J. Anthony , Robert Gomez , Samson M. Jolly , John Jin Lim , Dai-shi Su
IPC分类号： A61K31/505 , A61K31/12 , C07D417/00 , C07D239/00 , C07C233/00
CPC分类号： C07D213/82 , C07C307/02 , C07C309/65 , C07C309/66 , C07C309/67 , C07C309/76 , C07C311/09 , C07C311/46 , C07C2601/02 , C07D215/58 , C07D239/28 , C07D417/12
摘要： N-(Sulfonyloxybiarylmethyl) aminocyclopropanecarboxamide derivatives are bradykinin B1 antagonists or inverse agonists useful in the treatment or prevention of symptoms such as pain and inflammation associated with the bradykinin B1 pathway.
摘要翻译： N-（磺酰氧基联芳基甲基）氨基环丙烷甲酰胺衍生物是缓激肽B1拮抗剂或反激动剂，其可用于治疗或预防与缓激肽B1途径相关的疼痛和炎症等症状。

7. 发明授权

US5029694A Bottle erecting device 失效
标题翻译：瓶装设备
公开(公告)号：US5029694A
公开(公告)日：1991-07-09
申请号：US430678
申请日：1989-11-01
申请人： Robert Gomez
发明人： Robert Gomez
IPC分类号： B65G47/52 , B65G47/248 , B65G47/252 , B65G47/74
CPC分类号： B65G47/252 , B65G2201/0244 , B65G2207/14
摘要： An erecting device for bottles transported in recumbent position by a rope conveyor rotates the bottles to an upright position and deposits them on an apron conveyor which is positioned at a lower level at the end of the rope conveyor. The erecting device includes a pulley having two outer flanges, a pair of washers between the flanges and a pair of deformable rubber disks between the washers for holding a bottle during rotation from the recumbent to the vertical position. Each outer flange is connected to the rotating pulley axle by a respective intermediate cotter. The cotters are adjustably translatable along the length of the pulley axle such that the spacing between the rubber disks is adjustable to accommodate different bottle dimensions.
摘要翻译：用于通过绳索传送器在卧式运输中运输的瓶子的竖立装置将瓶子旋转到直立位置，并将它们沉积在位于绳索输送机端部的较低水平的围裙输送机上。竖立装置包括具有两个外部凸缘的滑轮，在凸缘之间的一对垫圈和垫圈之间的一对可变形的橡胶盘，用于在从卧式旋转到垂直位置时保持瓶子。每个外凸缘通过相应的中间开口连接到旋转滑轮轴。开口沿着皮带轮轴的长度可调节地平移，使得橡胶盘之间的间隔是可调节的，以适应不同的瓶子尺寸。

8. 发明授权

US10542845B2 Foodstuff receptacle for beverage container 有权
公开(公告)号：US10542845B2
公开(公告)日：2020-01-28
申请号：US14707136
申请日：2015-05-08
申请人： Juan J. Herrera, Jr. , Robert Gomez, III
发明人： Juan J. Herrera, Jr. , Robert Gomez, III
IPC分类号： A47J47/02 , B65D25/04 , B65D51/28 , B65D25/20
摘要： A receptacle for holding a foodstuff that is attachable to a beverage container is disclosed. The receptacle of the present disclosure allows a person to be able to hold a beverage and a foodstuff in one hand.

9. 发明授权

US10500664B2 Cutting torch guide assembly 有权
公开(公告)号：US10500664B2
公开(公告)日：2019-12-10
申请号：US15584160
申请日：2017-05-02
申请人： Robert Gomez , Richard Gomez
发明人： Robert Gomez , Richard Gomez
IPC分类号： B23K7/10 , B26D7/00 , B23K37/02
CPC分类号： B23K7/10 , B23K37/0205 , B23K37/027 , B26D7/0006
摘要： A cutting torch guide assembly for cutting beveled openings includes a first rod that is hollow. A first sleeve is positioned around and slidably positionable on the first rod. A pin is coupled to and extends perpendicularly from the first sleeve. The pin is configured to couple to a metal substrate to define an axis of a penetration that is to be cut into the metal substrate. A second rod is positioned in and selectively extensible from the first rod. The first sleeve is positionable to select a diameter of the penetration on an opposing side of the metal substrate. The second rod is positionable relative to the first rod to select a thickness of the metal substrate. A ring coupled to the second rod is configured to insert a nozzle of a cutting torch so that the nozzle is positioned to cut a beveled penetration into the substrate.

10. 发明申请

US20180318953A1 Cutting Torch Guide Assembly 审中-公开
公开(公告)号：US20180318953A1
公开(公告)日：2018-11-08
申请号：US15584160
申请日：2017-05-02
申请人： Robert Gomez , Richard Gomez
发明人： Robert Gomez , Richard Gomez
IPC分类号： B23K7/10 , B26D7/00
CPC分类号： B23K7/10 , B26D7/0006
摘要： A cutting torch guide assembly for cutting beveled openings includes a first rod that is hollow. A first sleeve is positioned around and slidably positionable on the first rod. A pin is coupled to and extends perpendicularly from the first sleeve. The pin is configured to couple to a metal substrate to define an axis of a penetration that is to be cut into the metal substrate. A second rod is positioned in and selectively extensible from the first rod. The first sleeve is positionable to select a diameter of the penetration on an opposing side of the metal substrate. The second rod is positionable relative to the first rod to select a thickness of the metal substrate. A ring coupled to the second rod is configured to insert a nozzle of a cutting torch so that the nozzle is positioned to cut a beveled penetration into the substrate.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式