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    • 9. 发明授权
    • Method for making cellulose semipermeable hollow fibers
    • 纤维素半透性中空纤维的制造方法
    • US4543221A
    • 1985-09-24
    • US313443
    • 1981-10-21
    • David T. ChenRobert D. Mahoney
    • David T. ChenRobert D. Mahoney
    • D01D5/24D01F1/10A61M1/03
    • B01D71/10B01D69/08D01D5/24
    • Improved cellulose semipermeable hollow fibers useful in detoxifying blood during hemodialysis or hemofiltration treatments. The cellulose fibers are fine, capillary fibers that are made by melt extrusion of certain cellulose ester polyol melt spin compositions into self-supporting gelled fibers. The cellulose ester gelled fibers are subsequently chemically converted into cellulose fibers by deacetylation, in aqueous alkali solution. The product fibers exhibit improved wet intrinsic tensile strength and higher water permeability characteristics than heretofore known cellulose fibers made from cellulose ester spin compositions.The invention includes the method of making the improved fibers and separatory cells such as hemodialyzers or hemofilters which contain the improved fibers in a gamma ray sterilized condition.
    • 改善纤维素半透性中空纤维,用于血液透析或血液滤过治疗中对血液进行解毒。 纤维素纤维是通过将某些纤维素酯多元醇熔融自旋组合物熔融挤出成自支撑胶凝纤维制成的细毛细纤维。 纤维素酯凝胶化纤维随后在碱性水溶液中通过脱乙酰化将其转化成纤维素纤维。 产品纤维表现出比迄今为止已知的由纤维素酯纺丝组合物制成的纤维素纤维更好的湿固有拉伸强度和更高的透水性。 本发明包括在伽马射线灭菌条件下制备改进的纤维和分离细胞如血液透析器或血液滤器的方法,其含有改进的纤维。