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1. 发明申请

US20110228890A1 SYSTEM AND METHOD FOR CREATING LIQUID DROPLET IMPACT FORCED COLLAPSE OF LASER NANOPARTICLE NUCLEATED CAVITIES 失效
标题翻译：用于创建激光纳米核心核心液体液滴冲击强迫收缩的系统和方法
公开(公告)号：US20110228890A1
公开(公告)日：2011-09-22
申请号：US12263901
申请日：2008-11-03
申请人： Robert C. Dean, JR. , R. Glynn Holt , Ronald A. Roy
发明人： Robert C. Dean, JR. , R. Glynn Holt , Ronald A. Roy
IPC分类号： G21B1/00 , B41J2/015
CPC分类号： G21B3/00 , H05H6/00 , Y02E30/18
摘要： A device, method and system for causing a controlled collapse of cavities formed within liquid droplets wherein a pressurized jet comprising a liquid and nanoparticle material produces droplets from the breakup of the jet stream. The liquid droplets may be irradiated with energy to produce and expand cavities formed within the droplets by irradiation of the nanoparticles contained within the droplets or alternatively, a volatile fluid with or without a metal nanoparticle may form the cavity. The droplets are collided with a target to collapse the cavities within the droplets. The irradiating (if provided) and colliding are timed to enhance implosion energy resulting from the cavities' collapse. The implosion energy and the fuel in the cavity may be used to activate and sustain a fusion reaction or from any other purposes.
摘要翻译：一种用于引起在液滴内形成的腔的受控塌陷的装置，方法和系统，其中包括液体和纳米颗粒材料的加压射流从喷射流的分解产生液滴。可以用能量照射液滴以通过照射包含在液滴内的纳米颗粒来产生和扩展在液滴内形成的空腔，或者备选地，具有或不具有金属纳米颗粒的挥发性流体可以形成空腔。液滴与靶碰撞以使液滴内的空腔折叠。照射（如果提供）和碰撞的时间是为了增强由空腔塌陷引起的内爆能量。内腔中的内爆能量和燃料可用于激活和维持聚变反应或来自任何其他目的。

2. 发明授权

US06585774B2 Dynamic variable geometry fitting system for use with a body appliance 有权
公开(公告)号：US06585774B2
公开(公告)日：2003-07-01
申请号：US09840955
申请日：2001-04-24
申请人： Robert C. Dean, Jr. , Michael B. Mayor , David F. Nelson , Chad S. Braley , Mark W. Blanchard
发明人： Robert C. Dean, Jr. , Michael B. Mayor , David F. Nelson , Chad S. Braley , Mark W. Blanchard
IPC分类号： A61F280
CPC分类号： A61F2/76 , A61F2/68 , A61F2/7843 , A61F2002/501 , A61F2002/745 , A61F2002/748 , A61F2002/7655 , A61F2002/802 , A61F2002/805
摘要： A dynamic variable geometry fitting system with fluid-filled bladders and automatically regulating their volumes to provide a continuously secure fit. This system can vary volume continuously to accommodate natural variation in an amputee's residuum. It makes reliable suction retention of a prosthesis easier for the prosthetist to achieve while reducing the potential for tissue lesions. By maintaining a continuous, secure fit, the amputee's sense of confidence and willingness to use the prosthesis increases.

3. 发明授权

US5833861A Perfusive chromatography 失效
公开(公告)号：US5833861A
公开(公告)日：1998-11-10
申请号：US800786
申请日：1997-02-14
申请人： Noubar B. Afeyan , Fred E. Regnier , Robert C. Dean, Jr.
发明人： Noubar B. Afeyan , Fred E. Regnier , Robert C. Dean, Jr.
IPC分类号： B01D15/08 , B01D15/34 , G01N30/52
CPC分类号： B01J20/285 , B01D15/345 , B01J20/28092 , B01J20/28095 , B01J2220/54 , G01N2030/528
摘要： Disclosed are chromatography methods and matrix geometries which permit high resolution, high productivity separation of mixtures of solutes, particularly biological materials. The method involves passing fluids through specially designed chromatography matrices at high flow rates. The matrices define first and second interconnected sets of pores and a high surface area for solute interaction in fluid communication with the members of the second set of pores. The first and second sets of pores are embodied, for example, as the interstices among particles and throughpores within the particles. The pores are dimensioned such that, at achievable high fluid flow rates, convective flow occurs in both pore sets, and the convective flow rate exceeds the rate of solute diffusion in the second pore set. This approach couples convective and diffusive mass transport to and from the active surface and permits increases in fluid velocity without the normally expected bandspreading.

4. 发明授权

US5228989A Perfusive chromatography 失效
标题翻译：渗透色谱法
公开(公告)号：US5228989A
公开(公告)日：1993-07-20
申请号：US988028
申请日：1992-12-09
申请人： Noubar B. Afeyan , Fred E. Regnier , Robert C. Dean, Jr.
发明人： Noubar B. Afeyan , Fred E. Regnier , Robert C. Dean, Jr.
IPC分类号： B01D15/08 , B01D15/34 , G01N30/52
CPC分类号： B01J20/285 , B01D15/345 , B01J20/28092 , B01J20/28095 , B01J2220/54 , G01N2030/528
摘要： Disclosed are chromatography methods and matrix geometries which permit high resolution, high productivity separation of mixtures of solutes, particularly biological materials. The method involves passing fluids through specially designed chromatography matrices at high flow rates. The matrices define first and second interconnected sets of pores and a high surface area for solute interaction in fluid communication with the members of the second set of pores. The first and second sets of pores are embodied, for example, as the interstices among particles and throughpores within the particles. The pores are dimensioned such that, at achievable high fluid flow rates, convective flow occurs in both pore sets, and the convective flow rate exceeds the rate of solute diffusion in the second pore set. This approach couples convective and diffusive mass transport to and from the active surface and permits increases in fluid velocity without the normally expected bandspreading.
摘要翻译：公开了色谱方法和基质几何形状，其允许溶质，特别是生物材料的混合物的高分辨率，高生产率分离。该方法包括以高流速将流体通过专门设计的色谱基质。这些基质定义了第一和第二相互连接的孔组，以及用于与第二组孔的构件流体连通的溶质相互作用的高表面积。第一和第二组孔体现为例如颗粒内的颗粒和透孔之间的间隙。孔的尺寸使得在可实现的高流体流速下，在两个孔组中都发生对流，并且对流流速超过第二孔组中溶质扩散的速率。这种方法将对流和扩散质量传输与活性表面相耦合，并允许流体速度的增加而没有通常预期的带扩展。

5. 发明授权

US4997753A Weighted collagen microsponge for immobilizing bioactive material 失效
标题翻译：用于固定生物活性物质的加重胶原微球
公开(公告)号：US4997753A
公开(公告)日：1991-03-05
申请号：US393656
申请日：1989-08-14
申请人： Robert C. Dean, Jr. , Frederick H. Silver , Richard A. Berg , Philip G. Phillips , Peter W. Runstadler, Jr.
发明人： Robert C. Dean, Jr. , Frederick H. Silver , Richard A. Berg , Philip G. Phillips , Peter W. Runstadler, Jr.
IPC分类号： C12N1/00 , C12N5/00 , C12N5/02 , C12N11/02 , C12P1/00
CPC分类号： C12N11/02 , C12N1/00 , C12N5/0075 , C12P1/00 , C12N2533/54
摘要： Weighted collagen microsponges having a highly crosslinked collagen matrix are described suitable for use in culturing organisms in motive reactor systems. The microsponges have an open to the surface pore structure, and pore sizes and volumes suitable for immobilizing a variety of bioactive materials. The microsponges also have an average particle size in the range of about 100 to about 1000 microns and a specific gravity above about 1.05.
摘要翻译：描述了具有高度交联的胶原基质的加重胶原微球适用于在动力反应器系统中培养生物体。微球具有开放的表面孔结构，并且适合于固定各种生物活性材料的孔径和体积。微球也具有约100至约1000微米范围内的平均粒度和约1.05以上的比重。

6. 发明授权

US07611579B2 Systems and methods for synthesis of extended length nanostructures 有权
标题翻译：用于合成延长长度纳米结构的系统和方法
公开(公告)号：US07611579B2
公开(公告)日：2009-11-03
申请号：US11035471
申请日：2005-01-14
申请人： David Lashmore , Joseph J. Brown , Robert C. Dean, Jr. , Peter L. Antoinette
发明人： David Lashmore , Joseph J. Brown , Robert C. Dean, Jr. , Peter L. Antoinette
IPC分类号： C30B23/00 , C30B28/12 , H01L21/322 , C03C17/00
CPC分类号： B82Y40/00 , B82Y10/00 , B82Y30/00 , C01B32/162 , C01B2202/34 , Y10S438/909 , Y10S977/70 , Y10S977/701 , Y10S977/702 , Y10S977/844 , Y10S977/89 , Y10S977/963 , Y10T428/249978 , Y10T428/2916 , Y10T428/2918 , Y10T428/298 , Y10T442/60 , Y10T442/605
摘要： A system for synthesizing nanostructures using chemical vapor deposition (CVD) is provided. The system includes a housing, a porous substrate within the housing, and on a downstream surface of the substrate, a plurality of catalyst particles from which nanostructures can be synthesized upon interaction with a reaction gas moving through the porous substrate. Electrodes may be provided to generate an electric field to support the nanostructures during growth. A method for synthesizing extended length nanostructures is also provided. The nanostructures are useful as heat conductors, heat sinks, windings for electric motors, solenoid, transformers, for making fabric, protective armor, as well as other applications.
摘要翻译：提供了一种使用化学气相沉积（CVD）合成纳米结构的系统。该系统包括壳体，壳体内的多孔基底，以及在基底的下游表面上，多个催化剂颗粒，当与通过多孔基底移动的反应气体相互作用时，可从该催化剂颗粒合成纳米结构。可以提供电极以在生长期间产生电场以支持纳米结构。还提供了一种合成延伸长度纳米结构的方法。纳米结构可用作热导体，散热器，用于电动机的绕组，螺线管，变压器，用于制造织物，保护性装甲以及其它应用。

7. 发明授权

US06270445B1 In-bed exercise machine and method of use 有权
标题翻译：床上运动机及使用方法
公开(公告)号：US06270445B1
公开(公告)日：2001-08-07
申请号：US09666740
申请日：2000-09-20
申请人： Robert C. Dean, Jr. , Solomon Diamond , Elizabeth K. Deneen , Amanda G. Heermans , Gayle B. O'Neil , David S. Smith
发明人： Robert C. Dean, Jr. , Solomon Diamond , Elizabeth K. Deneen , Amanda G. Heermans , Gayle B. O'Neil , David S. Smith
IPC分类号： A63B2100
CPC分类号： A61H1/0259 , A61H1/0262 , A61H2201/0157 , A61H2201/1215 , A61H2201/1238 , A61H2201/1246 , A61H2201/1642 , A61H2201/5007 , A61H2201/5038 , A61H2201/5043 , A61H2201/5079 , A61H2203/0456 , A61H2230/065 , A61H2230/105 , A61H2230/208 , A61H2230/305 , A61H2230/605
摘要： Methods of use of a portable in-bed exercising machine are provided for strengthening and/or strength maintenance of the musculature and ligaments associated with an extremity. The exercise apparatus employs the principles of closed kinetic chain exercise of the extremity in both concentric and eccentric modes and for isometric, isotonic and isokinetic exercise. Each extremity is engaged separately allowing for bilateral, unilateral and reciprocal motion. As exemplified for lower extremities, force is actively applied to the feet with each lower extremity having the force level continuously adjustable from zero force to a force equal to or greater than body-weight The exercise motions and force applications use the same major muscle groups as functional activities such as standing from a chair, climbing stairs walling, jumping and jogging. Vertical support is provided for the lower extremity to stabilize and control the lower extremity motion within safe limits. Back support is provided for the user to exercise in a supine position. Almost any bed may be integrated with the force producing machine to form the exercise apparatus. The methods of use are adaptable to low gravity environments such as space stations, space shuttles, and other space-like environments.
摘要翻译：使用便携式床上运动机器的方法用于加强和/或强度维持与肢体相关的肌肉和韧带。运动器械采用同步和偏心模式的肢体闭合动力学运动的原理，以及等长，等渗和等速运动。每个肢体分别进行允许双边，单方和互惠的动议。如下肢所示，力被积极地施加到脚，每个下肢具有从零力连续调节到等于或大于体重的力的运动运动和力应用使用相同的主要肌肉组功能活动，如从椅子上站立，爬楼梯，跳跃和慢跑。为下肢提供垂直支撑，以在安全限度内稳定和控制下肢运动。背部支撑被提供给使用者仰卧位锻炼。几乎任何床可以与力产生机一体形成锻炼装置。使用的方法适用于低重力环境，如空间站，航天飞机和其他类似空间的环境。

8. 发明授权

US5597497A Switch mechanism for operating a plasma arc torch, other tools or weapons 失效
标题翻译：用于操作等离子弧焊炬，其他工具或武器的开关机构
公开(公告)号：US5597497A
公开(公告)日：1997-01-28
申请号：US359909
申请日：1994-12-20
申请人： James C. Dean , Robert C. Dean, Jr. , E. Hubbard Yonkers
发明人： James C. Dean , Robert C. Dean, Jr. , E. Hubbard Yonkers
IPC分类号： H05H1/34 , B23K10/00
CPC分类号： H05H1/34 , H05H2001/3473
摘要： A switch mechanism with a safety member for operating a tool or a weapon which reduces the probability of inadvertent operation. The switch mechanism comprises a trigger and a safety member disposed adjacent to the trigger for preventing the trigger from contacting an actuation switch. The safety member is shaped such that when it is positioned in a first position, it prevents the trigger from contacting the switch. In addition, the safety member is shaped such that when the safety member is positioned in a second position, it allows the trigger to contact the actuation switch.
摘要翻译：具有用于操作工具或武器的安全构件的开关机构，其降低了意外操作的可能性。开关机构包括触发器和与触发器相邻设置的安全构件，用于防止触发器与致动开关接触。安全构件的形状使得当其位于第一位置时，其防止触发器与开关接触。此外，安全构件被成形为使得当安全构件定位在第二位置时，其允许触发器与致动开关接触。

9. 发明授权

US5552041A Perfusive chromatography 失效
公开(公告)号：US5552041A
公开(公告)日：1996-09-03
申请号：US317161
申请日：1994-10-03
申请人： Noubar B. Afeyan , Fred E. Regnier , Robert C. Dean, Jr.
发明人： Noubar B. Afeyan , Fred E. Regnier , Robert C. Dean, Jr.
IPC分类号： B01D15/08 , B01D15/34 , G01N30/52
CPC分类号： B01J20/285 , B01D15/345 , B01J20/28092 , B01J20/28095 , B01J2220/54 , G01N2030/528
摘要： Disclosed are chromatography methods and matrix geometries which permit high resolution, high productivity separation of mixtures of solutes, particularly biological materials. The method involves passing fluids through specially designed chromatography matrices at high flow rates. The matrices define first and second interconnected sets of pores and a high surface area for solute interaction in fluid communication with the members of the second set of pores. The first and second sets of pores are embodied, for example, as the interstices among particles and throughpores within the particles. The pores are dimensioned such that, at achievable high fluid flow rates, convective flow occurs in both pore sets, and the convective flow rate exceeds the rate of solute diffusion in the second pore set. This approach couples convective and diffusive mass transport to and from the active surface and permits increases in fluid velocity without the normally expected bandspreading.

10. 发明授权

US4978616A Fluidized cell cultivation process 失效
标题翻译：流化细胞培养过程
公开(公告)号：US4978616A
公开(公告)日：1990-12-18
申请号：US92599
申请日：1987-09-03
申请人： Robert C. Dean, Jr. , Peter V. Grela , Subhash B. Karkare , Peter W. Runstadler, Jr.
发明人： Robert C. Dean, Jr. , Peter V. Grela , Subhash B. Karkare , Peter W. Runstadler, Jr.
IPC分类号： C07K14/59 , C12M1/40 , C12M3/02 , C12N5/00 , C12P7/06
CPC分类号： C12P7/06 , C07K14/59 , C12M23/58 , C12M25/20 , C12M27/02 , C12N5/0075 , C12N2531/00 , Y02E50/17 , Y10S435/813 , Y10S435/819
摘要： A fluidized bed reactor and reaction process, particularly well-suited for culturing cells, for example, for tissue culture and fermentation processes, are described which involve the treatment of at least a portion of the fluid exiting the fluidized bed reactor in a side loop in a manner to alter its temperature or composition, e.g., oxygenation, with recirculation of this treated fluid to the reactor as a portion of the fluid causing bed fluidization.
摘要翻译：描述了特别适用于培养细胞的流化床反应器和反应方法，例如用于组织培养和发酵方法，其涉及在侧循环中处理离开流化床反应器的至少一部分流体一种改变其温度或组成，例如氧合的方式，将该处理过的流体再循环到反应器中作为导致床流化的流体的一部分。

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