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1. 发明申请

WO2011071778A1 DEVICE FOR THE DELINEATION OF CARDIOVASCULAR OR OTHER ANATOMICAL STRUCTURES 审中-公开
标题翻译：用于分离心脏血管或其他解剖结构的装置
公开(公告)号：WO2011071778A1
公开(公告)日：2011-06-16
申请号：PCT/US2010/058954
申请日：2010-12-03
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , SORAJJA, Paul , RIHAL, Charanjit, S.
发明人： SORAJJA, Paul , RIHAL, Charanjit, S.
IPC分类号： A61M25/01 , A61B19/00
CPC分类号： A61M25/0105 , A61B17/00491 , A61B90/39 , A61B2017/00778 , A61B2017/22051 , A61B2090/3912 , A61B2090/3987 , A61B2090/3991 , A61F2/958 , A61M25/1002 , A61M25/1011 , A61M25/104 , A61M29/02 , A61M2025/105 , A61M2025/1059 , A61M2025/1075 , A61M2025/1079 , A61M2025/1097
摘要： A method and device for delineating structures includes a catheter for insertion at the structure, an expandable component operatively having proximal, distal and intermediate segments shiftable between a collapsed state and an expanded state, with the intermediate segment shiftable independently of the proximal and distal segments. A marking medium is carried by a portion of the intermediate segment, and the marking medium detectable using a selected imaging device. The marking medium is arranged to be transferable from the intermediate segment to portions of the cardiovascular structure upon shifting the intermediate segment to the expanded position with the intermediate segment in the desired position.
摘要翻译：用于描绘结构的方法和装置包括用于插入结构的导管，可操作地具有在折叠状态和展开状态之间移动的近端，远端和中间段的可扩张部件，其中中间段可以独立于近端段和远端段移位。标记介质由中间段的一部分承载，并且使用选定的成像装置可检测标记介质。标记介质被布置成在将中间段移动到期望位置时将中间段移动到扩展位置时可从中间段转移到心血管结构的部分。

2. 发明申请

WO2009108699A3 CONFORMABLE STENTS AND METHODS FOR MAKING 审中-公开
公开(公告)号：WO2009108699A3
公开(公告)日：2009-09-03
申请号：PCT/US2009/035139
申请日：2009-02-25
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , SANDHU, Gurpreet S. , DRAGOMIR DAESCU, Dan , RIHAL, Charanjit S. , ASIRVATHAM, Samuel J.
发明人： SANDHU, Gurpreet S. , DRAGOMIR DAESCU, Dan , RIHAL, Charanjit S. , ASIRVATHAM, Samuel J.
IPC分类号： A61F2/86 , A61M29/00 , A61F2/82 , A61L27/52 , A61L27/14 , A61L27/54
摘要： Materials and methods for making conformable stents. The stents can be generated by, for example, injecting a fluid into a scaffold on the outer surface of an angioplasty balloon inflated at the site of a stenosis, and allowing the fluid to harden or set, thus generating a stent that can remain in the vessel at the site of stenosis.

3. 发明申请

WO2019108287A1 DELIVERY AND OCCLUSION DEVICES FOR PARAVALVULAR LEAK 审中-公开
公开(公告)号：WO2019108287A1
公开(公告)日：2019-06-06
申请号：PCT/US2018/049586
申请日：2018-09-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , RIHAL, Charanjit S.
发明人： RIHAL, Charanjit S. , GRUBA, Sarah M. , BALDWIN, Katherine L. , ROHL, James P. , COLLEGE, Todd
IPC分类号： A61B17/122 , A61B17/128 , A61B17/00 , A61F2/24
CPC分类号： A61B17/12122 , A61B1/00 , A61B1/05 , A61B1/0676 , A61B17/12136 , A61B17/12172 , A61B17/1227 , A61B17/1285 , A61B2017/00243 , A61B2017/00314 , A61B2017/00557 , A61B2017/00783 , A61B2017/00867 , A61B2017/1205 , A61F2/24 , A61F2/2427 , A61F2/246 , A61F2/2466 , A61F2210/0014 , A61F2230/001 , A61F2230/0039 , A61F2250/0003 , A61F2250/0069 , A61F2310/00011
摘要： The present disclosure relates generally to apparatuses and methods for delivering an occlusion device to a paravalvular leak. In some embodiments, a paravalvular occlusion apparatus includes a catheter having main body including a proximal end and a distal end, a visualization element disposed in the distal end of the main body, and a working channel extending from the distal end of the main body. The catheter further includes an elongate shaft extendable from the working channel, wherein an occlusion device is coupled to the elongate shaft. In some embodiments, an occlusion device includes a leading end including a first section, and a trailing end opposite the leading end, the trailing end including a second section. The first section and the second section of the occlusion device are operable to be positioned along a perimeter of a prosthetic valve for blocking the paravalvular leak.

4. 发明申请

WO2007139799A3 DEVICES AND METHODS FOR CROSSING CHRONIC TOTAL OCCLUSIONS 审中-公开
标题翻译：用于交叉治疗慢性阻塞性疾病的装置和方法
公开(公告)号：WO2007139799A3
公开(公告)日：2008-10-16
申请号：PCT/US2007012214
申请日：2007-05-22
申请人： MAYO FOUNDATION , SANDHU GURPREET S , RIHAL CHARANJIT S
发明人： SANDHU GURPREET S , RIHAL CHARANJIT S
IPC分类号： A61M29/00
CPC分类号： A61B17/3207 , A61B2017/00858 , A61B2017/22094 , A61M25/0043 , A61M25/0662 , A61M29/00 , A61M2025/006
摘要： Devices and methods for crossing total chronic occlusions in body lumens which may involve guidewire assisted delivery of a device to traverse a chronic total occlusion (CTO) and create a passageway through the CTO for a treatment device. Some devices of the present invention may include an expandable sleeve that expands in response to temperature changes. In other devices, an expandable sleeve is provided in which interlocking sections are arranged such that they have a first, smaller diameter enabling insertion through a CTO. The expandable sleeve can assume a second, larger diameter by moving the interlocking cylindrical sections relative to each other. In other aspects, a guide catheter may include a friction-enhanced outer surface to assist in maintaining the guide catheter in a selected location during use. The friction-enhanced property may be provided using, e.g., materials with an increased coefficient of friction, adding features to an otherwise smooth surface, etc.
摘要翻译：用于穿过体腔内的全部慢性闭塞的装置和方法，其可以涉及导丝辅助递送装置以横穿慢性完全闭塞（CTO）并且通过用于治疗装置的CTO创建通道。本发明的一些装置可以包括响应于温度变化而膨胀的可膨胀套筒。在其它装置中，提供了一种可膨胀套筒，其中互锁部分布置成使得它们具有能够穿过CTO插入的第一较小直径。可膨胀套筒可以相对于彼此移动互锁的圆柱形部分而呈现第二较大的直径。在其他方面，引导导管可以包括摩擦增强的外表面，以在使用期间辅助将引导导管保持在选定的位置。可以使用例如具有增加的摩擦系数的材料，将特征添加到其它光滑表面等来提供摩擦增强特性。

5. 发明申请

WO2009108699A2 CONFORMABLE STENTS AND METHODS FOR MAKING 审中-公开
标题翻译：一致的制造方法和制造方法
公开(公告)号：WO2009108699A2
公开(公告)日：2009-09-03
申请号：PCT/US2009035139
申请日：2009-02-25
申请人： MAYO FOUNDATION , SANDHU GURPREET S , DRAGOMIR DAESCU DAN , RIHAL CHARANJIT S , ASIRVATHAM SAMUEL J
发明人： SANDHU GURPREET S , DRAGOMIR DAESCU DAN , RIHAL CHARANJIT S , ASIRVATHAM SAMUEL J
IPC分类号： A61F2/06 , A61F2/90 , A61L27/14 , A61L27/52 , A61L27/54 , A61M29/00
CPC分类号： A61F2/945 , A61F2/88 , A61F2/90 , A61F2/954 , A61F2/958 , A61F2002/065 , A61F2210/0085 , A61F2230/0067 , A61F2250/0039 , A61M25/1002 , A61M2025/1086
摘要： Materials and methods for making conformable stents. The stents can be generated by, for example, injecting a fluid into a scaffold on the outer surface of an angioplasty balloon inflated at the site of a stenosis, and allowing the fluid to harden or set, thus generating a stent that can remain in the vessel at the site of stenosis.
摘要翻译：制作适形支架的材料和方法。支架可以通过例如将流体注射到在狭窄部位膨胀的血管成形术球囊的外表面上的支架中，并且允许流体硬化或固定，从而产生可保留在支架中的支架血管狭窄部位。

6. 发明申请

WO2009089143A3 STENT ADVANCEMENT ASSISTANT AND LESION DILATOR WIRE 审中-公开
公开(公告)号：WO2009089143A3
公开(公告)日：2009-07-16
申请号：PCT/US2009/030094
申请日：2009-01-05
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , SANDHU, Gurpreet, S. , RIHAL, Charanjit, S. , GULATI, Rajiv , BRESNAHAN, John, F.
发明人： SANDHU, Gurpreet, S. , RIHAL, Charanjit, S. , GULATI, Rajiv , BRESNAHAN, John, F.
IPC分类号： A61M25/02 , A61M25/09 , A61M25/10
摘要： Materials and methods for placement of catheters, stents, and other therapeutic or diagnostic devices in blood vessels.

7. 发明公开

EP3716868A1 DELIVERY AND OCCLUSION DEVICES FOR PARAVALVULAR LEAK 有权转让
公开(公告)号：EP3716868A1
公开(公告)日：2020-10-07
申请号：EP18778724.7
申请日：2018-09-05
申请人： Boston Scientific Scimed, Inc. , Mayo Foundation for Medical Education and Research , Rihal, Charanjit S.
发明人： RIHAL, Charanjit S. , GRUBA, Sarah M. , BALDWIN, Katherine L. , ROHL, James P. , COLLEGE, Todd
IPC分类号： A61B17/122 , A61B17/128 , A61B17/00 , A61F2/24

8. 发明申请

WO2009089143A2 STENT ADVANCEMENT ASSISTANT AND LESION DILATOR WIRE 审中-公开
标题翻译： STENT ADVANCEMENT ASSISTANT和LESION DILATOR WIRE
公开(公告)号：WO2009089143A2
公开(公告)日：2009-07-16
申请号：PCT/US2009030094
申请日：2009-01-05
申请人： MAYO FOUNDATION , SANDHU GURPREET S , RIHAL CHARANJIT S , GULATI RAJIV , BRESNAHAN JOHN F
发明人： SANDHU GURPREET S , RIHAL CHARANJIT S , GULATI RAJIV , BRESNAHAN JOHN F
IPC分类号： A61M25/02 , A61M25/09 , A61M25/10
CPC分类号： A61M25/09 , A61F2/95 , A61F2250/0062 , A61M25/09041 , A61M2025/09133
摘要： Materials and methods for placement of catheters, stents, and other therapeutic or diagnostic devices in blood vessels.
摘要翻译：用于在血管中放置导管，支架和其他治疗或诊断设备的材料和方法。

9. 发明申请

WO2007139799A2 DEVICES AND METHODS FOR CROSSING CHRONIC TOTAL OCCLUSIONS 审中-公开
标题翻译：用于交叉治疗慢性阻塞性疾病的装置和方法
公开(公告)号：WO2007139799A2
公开(公告)日：2007-12-06
申请号：PCT/US2007/012214
申请日：2007-05-22
申请人： MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH , SANDHU, Gurpreet, S. , RIHAL, Charanjit, S.
发明人： SANDHU, Gurpreet, S. , RIHAL, Charanjit, S.
IPC分类号： A61B17/3209
CPC分类号： A61B17/3207 , A61B2017/00858 , A61B2017/22094 , A61M25/0043 , A61M25/0662 , A61M29/00 , A61M2025/006
摘要： Devices and methods for crossing total chronic occlusions in body lumens (e.g., blood vessels, etc.). The devices and methods may involve guidewire assisted delivery of a device designed to both traverse a chronic total occlusion (CTO) and create a passageway through the CTO for a treatment device (e.g., an angioplasty balloon, stent, etc.). Some devices of the present invention may include an expandable sleeve constructed of material that expands in response to temperature changes. In other devices, an expandable sleeve may be provided in which two or more interlocking cylindrical sections can be arranged such that the cylindrical sections have a first, smaller diameter at which the expandable sleeve can be inserted through a CTO. The expandable sleeve also has a second, larger diameter that can be achieved by moving the two or more interlocking cylindrical sections relative to each other such that the expandable sleeve moves from the first diameter to the second diameter when the expandable sleeve is located across the CTO. In other aspects, a guide catheter may include a friction-enhanced outer surface to assist in maintaining the guide catheter in a selected location during use. The friction-enhanced property may be provided using, e.g., materials with an increased coefficient of friction, adding features to the surface of an otherwise smooth guide catheter, etc.
摘要翻译：用于穿过体腔（例如血管等）中的全部慢性闭塞的装置和方法。装置和方法可以包括设计成横穿慢性完全闭塞（CTO）并且通过用于治疗装置（例如血管成形术球囊，支架等）的CTO的通道的导丝辅助递送。本发明的一些装置可以包括由可响应于温度变化而膨胀的材料构成的可膨胀套筒。在其他装置中，可以提供可膨胀套筒，其中可以布置两个或更多个互锁圆柱形部分，使得圆柱形部分具有第一较小直径，在该直径下，可扩张套筒可以穿过CTO插入。可膨胀套筒还具有第二较大直径，其可以通过相对于彼此移动两个或更多个互锁的圆柱形部分来实现，使得当可膨胀套筒位于CTO周围时，可膨胀套筒从第一直径移动到第二直径。在其他方面，引导导管可以包括摩擦增强的外表面，以在使用期间辅助将引导导管保持在选定的位置。摩擦增强特性可以使用例如具有增加的摩擦系数的材料来提供，在另外平滑的引导导管的表面上增加特征等。

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