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1. 发明授权

US06495512B1 Salicylaldehyde-containing composition having antimicrobial and fragrancing properties and process for using same 有权
标题翻译：含有水杨醛的组合物具有抗微生物和芳香性质及其使用方法
公开(公告)号：US06495512B1
公开(公告)日：2002-12-17
申请号：US09603454
申请日：2000-06-23
申请人： Michael John Robert White , Maria Therese Lis-Balchin , Elisabeth J. M. Simpson , Stanley G. Deans , Remco Johannes Hendrik De Meijere
发明人： Michael John Robert White , Maria Therese Lis-Balchin , Elisabeth J. M. Simpson , Stanley G. Deans , Remco Johannes Hendrik De Meijere
IPC分类号： A61K746
CPC分类号： A61L9/12 , A01N35/04 , A61L9/01 , A61L9/042 , A01N49/00 , A01N43/38 , A01N31/16 , A01N31/08 , A01N31/06 , A01N31/04 , A01N2300/00
摘要： Described are synergistic antimicrobial-fragrance compositions including broad spectrum antimicrobial compositions containing salicylaldehyde and at least one organoleptically-compatible antimicrobial synergism cofactor substance. The weight ratio range of salicylaldehyde:synergism cofactors substance is from 1:10 up to 10:1. The cofactor substance is such that the degree of synergism of the resultant mixture is defined according to the IFF Antimicrobial Synergism Test wherein the difference between the actual and expected antimicrobial values of the mixture is greater than or equal to a multiple of (i) 0.05 and (ii) the expected antimicrobial value of the mixture. Cofactor substances include phenolics such as cresol, caravacrol and thymol; ethyl vanillin; benzyl alcohol; indol; &bgr;-orcinol; and terpinenol-4. Microorganisms against which the synergistic compositions are effective include: Escherichia coli; Enterococcus hirae; Pseudomonas aeruginosa; Staphylococcus aureus; and Saccharomyces cerevisae. The compositions have application in all-purpose cleaning compositions, gel-type toilet rim articles, liquid-type toilet rim articles, personal shower cleaning compositions, and body and hair care products including shower gel compositions, shampoo compositions and foam bath compositions.
摘要翻译：描述的是协同的抗微生物香料组合物，包括含有水杨醛和至少一种感官相容的抗微生物协同作用辅助物质的广谱抗微生物组合物。水杨醛：协同作用因子物质的重量比范围为1:10至10：1。辅助因子使得所得混合物的协同作用程度根据IFF抗微生物协同作用试验定义，其中混合物的实际和预期抗微生物值之间的差异大于或等于（i）0.05的倍数，和（ii）混合物的预期抗微生物价值。辅因子物质包括酚类如甲酚，卡伐卡罗和百里酚; 乙基香兰素; 苯甲醇; 无知的 β-淀粉酚和萜品烯酚-4。协同组合物有效的微生物包括：大肠杆菌;肠球菌;铜绿假单胞菌;金黄色葡萄球菌; 和酿酒酵母。该组合物可用于通用清洁组合物，凝胶型卫生间用品，液体式卫生间用品，个人淋浴清洁组合物以及包括沐浴露组合物，洗发剂组合物和泡沫浴组合物在内的身体和护发产品。

2. 发明授权

US06638904B2 Salicylaldehyde-containing composition having antimicrobial and fragrancing properties and process for using same 有权
公开(公告)号：US06638904B2
公开(公告)日：2003-10-28
申请号：US10291124
申请日：2002-11-08
申请人： Michael John Robert White , Maria Therese Lis-Balchin , Elisabeth J. M. Simpson , Stanley G. Deans , Remco Johannes Hendrik De Meijere
发明人： Michael John Robert White , Maria Therese Lis-Balchin , Elisabeth J. M. Simpson , Stanley G. Deans , Remco Johannes Hendrik De Meijere
IPC分类号： A61K746
CPC分类号： A61L9/12 , A01N35/04 , A61L9/01 , A61L9/042 , A01N49/00 , A01N43/38 , A01N31/16 , A01N31/08 , A01N31/06 , A01N31/04 , A01N2300/00
摘要： Described are synergistic antimicrobial-fragrance compositions including broad spectrum antimicrobial compositions containing salicylaldehyde and at least one organoleptically-compatible antimicrobial synergism cofactor substance. The weight ratio range of salicylaldehyde:synergism cofactors substance is from 1:10 up to 10:1. The cofactor substance is such that the degree of synergism of the resultant mixture is defined according to the IFF Antimicrobial Synergism Test wherein the difference between the actual and expected antimicrobial values of the mixture is greater than or equal to a multiple of (i) 0.05 and (ii) the expected antimicrobial value of the mixture. Cofactor substances include phenolics such as cresol, caravacrol and thymol; ethyl vanillin; benzyl alcohol; indol; &bgr;-orcinol; and terpinenol-4. Microorganisms against which the synergistic compositions are effective include: Escherichia coli; Enterococcus hirae; Pseudomonas aeruginosa; Staphylococcus aureus; and Saccharomyces cerevisae. The compositions have application in all-purpose cleaning compositions, gel-type toilet rim articles, liquid-type toilet rim articles, personal shower cleaning compositions, and body and hair care products including shower gel compositions, shampoo compositions and foam bath compositions.

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