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1. 发明申请

WO2012062554A3 LEAVE-ON NON-SOLID SKIN CONDITIONING COMPOSITIONS CONTAINING 12-[(12-HYDROXYOCTADECANOYL)OXY] OCTADECANOIC ACID 审中-公开
公开(公告)号：WO2012062554A3
公开(公告)日：2012-05-18
申请号：PCT/EP2011/068428
申请日：2011-10-21
申请人： UNILEVER PLC , UNILEVER N.V. , HINDUSTAN UNILEVER LIMITED , MADISON, Stephen, Alan , MOADDEL, Teanoosh , HARICHIAN, Bijan , ROSA, Jose, Guillermo , MELDRUM, Helen , LEE, Jianming
发明人： MADISON, Stephen, Alan , MOADDEL, Teanoosh , HARICHIAN, Bijan , ROSA, Jose, Guillermo , MELDRUM, Helen , LEE, Jianming
IPC分类号： A61Q19/08 , A61K8/37 , A61K8/67 , A61K8/365
摘要： Leave-on non-solid skin conditioning compositions containing 12-[(12- hydroxyoctadecanoyl)oxy] octadecanoic acid. 12-[(12-hydroxyoctadecanoyl)oxy] octadecanoic acid can be easily incorporated in combination with lipophilic carriers that are liquid at room temperature. Compositions are able to deliver increased energy production by human fibroblasts. Preferred compositions also contain 12-hydroxystearic acid and thus are able to deliver a wide range of skin benefits.

2. 发明申请

WO2012013417A3 SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED DIAMINES 审中-公开
标题翻译：包含取代二胺的皮肤护理组合物
公开(公告)号：WO2012013417A3
公开(公告)日：2012-04-05
申请号：PCT/EP2011059994
申请日：2011-06-16
申请人： UNILEVER PLC , UNILEVER NV , UNILEVER HINDUSTAN , ROSA JOSE GUILLERMO , HARICHIAN BIJAN , DRENNAN DIANA JEAN , BAJOR JOHN STEVEN , BOSKO CAROL ANNETTE
发明人： ROSA JOSE GUILLERMO , HARICHIAN BIJAN , DRENNAN DIANA JEAN , BAJOR JOHN STEVEN , BOSKO CAROL ANNETTE
IPC分类号： A61K8/41 , A61K8/49 , A61K8/69 , A61Q19/02
CPC分类号： A61K8/41 , A61K8/4913 , A61K8/69 , A61Q1/02 , A61Q5/02 , A61Q15/00 , A61Q19/02 , A61Q19/10
摘要： Skin care compositions comprising certain substituted diamines, which are particularly beneficial for skin lightening and achieving evenness of color, especially for face and underarm skin.
摘要翻译：包含某些取代二胺的皮肤护理组合物，其特别有益于亮肤和达到均匀的颜色，特别是对于面部和腋下皮肤。

3. 发明申请

WO2011054805A1 SUBSTITUTED 3-(PHENOXYMETHYL) BENZYL AMINES AND PERSONAL CARE COMPOSITIONS 审中-公开
标题翻译：取代的3-（苯甲酰基）苯甲酰胺和个人护理组合物
公开(公告)号：WO2011054805A1
公开(公告)日：2011-05-12
申请号：PCT/EP2010/066607
申请日：2010-11-02
申请人： UNILEVER PLC , UNILEVER N.V. , HINDUSTAN UNILEVER LIMITED , ROSA, Jose, Guillermo , HARICHIAN, Bijan , BAJOR, John, Steven , BOSKO, Carol, Annette , DRENNAN, Diana, Jean , NIP, John, Chun-Sing
发明人： ROSA, Jose, Guillermo , HARICHIAN, Bijan , BAJOR, John, Steven , BOSKO, Carol, Annette , DRENNAN, Diana, Jean , NIP, John, Chun-Sing
IPC分类号： C07C217/48 , A61K8/41 , A61K31/137 , A61P17/00 , A61Q5/08 , A61Q15/00 , A61Q19/02
CPC分类号： C07C217/48
摘要： Certain novel substituted 3-(phenoxymethyl) benzyl amines and personal care compositions comprising such, which are particularly beneficial for skin lightening and achieving evenness of color, especially for face and underarm skin.
摘要翻译：某些新颖的取代的3-（苯氧基甲基）苄基胺和包含这些的个人护理组合物，其特别有利于减轻皮肤并实现颜色均匀，特别是对于面部和腋下皮肤。

4. 发明申请

WO2011054804A2 SKIN CARE COMPOSITIONS COMPRISING PHENOXYALKYL AMINES 审中-公开
标题翻译：皮肤护理组合物包含苯甲酰胺
公开(公告)号：WO2011054804A2
公开(公告)日：2011-05-12
申请号：PCT/EP2010/066603
申请日：2010-11-02
申请人： UNILEVER PLC , UNILEVER N.V. , HINDUSTAN UNILEVER LIMITED , ROSA, Jose Guillermo , HARICHIAN, Bijan , BAJOR, John Steven , BOSKO, Carol Annette , DRENNAN, Diana Jean , NIP, John Chun-Sing
发明人： ROSA, Jose Guillermo , HARICHIAN, Bijan , BAJOR, John Steven , BOSKO, Carol Annette , DRENNAN, Diana Jean , NIP, John Chun-Sing
CPC分类号： A61K8/41 , A61K8/49 , A61K8/4946 , A61Q1/02 , A61Q5/02 , A61Q15/00 , A61Q19/02 , A61Q19/10
摘要： Skin care compositions comprising certain phenoxyalkylamines, which are particularly beneficial for skin lightening and achieving evenness of color, especially for face and underarm skin.
摘要翻译：包含某些苯氧基烷基胺的皮肤护理组合物，其特别有利于皮肤发亮并且实现颜色均匀，特别是对于面部和腋下皮肤。

5. 发明申请

WO2005085169A1 SKIN LIGHTENING AGENTS, COMPOSITIONS AND METHODS 审中-公开
标题翻译：皮肤发光剂，组合物和方法
公开(公告)号：WO2005085169A1
公开(公告)日：2005-09-15
申请号：PCT/EP2005/001595
申请日：2005-02-16
申请人： UNILEVER PLC , UNILEVER NV , HINDUSTAN LEVER LIMITED , HARICHIAN, Bijan , ROSA, Jose, Guillermo , BARRATT, Michael, James , BOSKO, Carol, Annette , BAJOR, John, Steven
发明人： HARICHIAN, Bijan , ROSA, Jose, Guillermo , BARRATT, Michael, James , BOSKO, Carol, Annette , BAJOR, John, Steven
IPC分类号： C07C59/52
CPC分类号： A61K8/365 , A61K8/37 , A61K2800/782 , A61Q19/02 , C07C59/52 , C07C69/732
摘要： The invention provides coumarin derived compounds of formula (I) as skin lightening agents alone or in combination with other skin benefit agents and together with a cosmetic vehicle : formula (I). Where each or both R 1 and/or R 2 represents hydrogen (H); linear or branched, saturated or unsaturated, C 1 -C 12 alkyl, alkenyl, acyl, or heteroalkyl (preferably, alkoxy) groups; and R 3 represents linear or branched, cyclic or acyclic, saturated or unsaturated, C 1 -C 12 alkyl, alkenyl, cycloalkyl, cycloalkenyl, or heteroalkyl group; R 5 represents a hydrogen atom (H), or R 4 ; and R 4 represents linear or branched, cyclic or acyclic, saturated or unsaturated, containing or not containing a heteroatom, C 1 -C 22 alkyl, alkenyl, cycloalkyl, cycloalkenyl, heteroalkyl, aryl, or heteroaryl group. The compounds, compositions and methods have effective skin lightening properties, may be less irritating to the skin, and are cost-effective and relatively simple to manufacture. Also provided are processes for making the compounds of general formula (I) from 4-substituted-7-hydroxy coumarin derivatives.
摘要翻译：本发明提供了香豆素衍生的式（I）化合物作为单独的皮肤增白剂或与其它皮肤有益剂组合以及化妆品载体：式（I）。其中R 1和/或R 2各自表示氢（H）; 直链或支链的饱和或不饱和的C1-C12烷基，烯基，酰基或杂烷基（优选烷氧基）; 且R 3表示直链或支链，环状或非环状，饱和或不饱和的C 1 -C 12烷基，烯基，环烷基，环烯基或杂烷基; R5表示氢原子（H）或R4; 且R 4表示含或不含杂原子，C 1 -C 22烷基，烯基，环烷基，环烯基，杂烷基，芳基或杂芳基的直链或支链，环状或无环的饱和或不饱和的。化合物，组合物和方法具有有效的皮肤发光特性，可能对皮肤刺激性较低，并且成本低廉且制造相对简单。还提供了由4-取代-7-羟基香豆素衍生物制备通式（I）的化合物的方法。

6. 发明申请

WO2007090553A3 COMPOUNDS USEFUL AS AGONISTS OF A2A ADENOSINE RECEPTORS, COSMETIC COMPOSITIONS WITH A2A AGONISTS AND A METHOD FOR USING THE SAME 审中-公开
公开(公告)号：WO2007090553A3
公开(公告)日：2007-08-16
申请号：PCT/EP2007/000847
申请日：2007-01-25
申请人： UNILEVER PLC , UNILEVER NV , HINDUSTAN UNILEVER LIMITED , NIP, John, Chun-Sing , BOSKO, Carol, Annette , ROSA, Jose, Guillermo , HARICHIAN, Bijan , SANTANA, Isabel, Cristina
发明人： NIP, John, Chun-Sing , BOSKO, Carol, Annette , ROSA, Jose, Guillermo , HARICHIAN, Bijan , SANTANA, Isabel, Cristina
IPC分类号： A61K8/60 , A61Q19/02 , A61K31/7076 , C07H19/167
摘要： Compounds useful as agonists of A 2A adenosine receptors are described. Also described is a cosmetically acceptable composition having an agonists of A 2A adenosine receptors where the composition is suitable to apply to human skin to reduce the effects of melanin, resulting in skin whitening.

7. 发明申请

WO2006097224A1 NOVEL RESORCINOL DERIVATIVES FOR SKIN 审中-公开
标题翻译：用于皮肤的新型RESORCINOL衍生物
公开(公告)号：WO2006097224A1
公开(公告)日：2006-09-21
申请号：PCT/EP2006/002099
申请日：2006-03-06
申请人： UNILEVER PLC , UNILEVER NV , HINDUSTAN LEVER LIMITED , HARICHIAN, Bijan , ROSA, Jose Guillermo
发明人： HARICHIAN, Bijan , ROSA, Jose Guillermo
IPC分类号： C07C69/017 , C07C39/17 , A61Q19/02 , A61K8/34 , A61K8/37
CPC分类号： C07C69/017 , C07C39/17 , C07C2601/14
摘要： New 4-substituted resorcinol derivatives of general formula (I) and/or B and process for synthesizing same, cosmetic compositions and methods of using same, particularly for skin lightening: formula (I) and formula (B) wherein, X 1 and/or X 2 represents hydrogen (H); linear or branched, saturated or unsaturated C 1 -C 12 alkyl, alkenyl, or acyl groups. Preferably, X 1 and/or X 2 represents hydrogen (H); linear or branched, saturated or unsaturated C 1 -C 12 alkyl or acyl groups. R 1 represents hydrogen (H); linear or branched, cyclic or acyclic, saturated or unsaturated C 1 -C 12 alkyl, alkenyl, cycloalkyl, or cycloalkenyl group. Preferably, R 1 represents hydrogen (H) or a C 1 alkyl group (i.e, methyl group). More preferably, R 1 represents hydrogen. n represents 0, 1. When n = 0, the ring is a cyclopentyl with or without one heteroatom from O, N or S and/or with or without one double bond. When n = 1, the ring is a cyclohexyl with or without one heteroatom from O, N or S and/or with or without one double bond. m represents an integer between 1 and 6.
摘要翻译：通式（I）和/或B的新的4-取代间苯二酚衍生物及其合成方法，化妆品组合物及其使用方法，特别是皮肤增亮：式（I）和式（B）其中X 1和/或X 2表示氢（H）; 直链或支链，饱和或不饱和的C 1 -C 12烷基，烯基或酰基。优选地，X 1和/或X 2代表氢（H）; 直链或支链，饱和或不饱和的C 1 -C 12烷基或酰基。 R 1表示氢（H）; 直链或支链，环状或非环状，饱和或不饱和的C 1 -C 12烷基，烯基，环烷基或环烯基。优选地，R 1表示氢（H）或C 1烷基（即甲基）。更优选地，R 1代表氢。当n = 0时，环是具有或不具有来自O，N或S的一个杂原子的环戊基和/或具有或不具有一个双键的环戊基。当n = 1时，环是具有或不具有来自O，N或S的一个杂原子和/或具有或不具有一个双键的环己基。 m表示1〜6的整数。

8. 发明申请

WO2006045427A1 PERSONAL CARE PRODUCTS WHICH INCLUDE DIHYDROXYPROPYLTRI (C1-C3 ALKYL) AMMONIUM SALTS 审中-公开
标题翻译：个人护理产品，其中包括二羟基丙酸（C1-C3烷基）氨基盐
公开(公告)号：WO2006045427A1
公开(公告)日：2006-05-04
申请号：PCT/EP2005/010905
申请日：2005-10-07
申请人： UNILEVER PLC , UNILEVER NV , HINDUSTAN LEVER LIMITED , HARICHIAN, Bijan , MCMANUS, Richard, Loren , ROSA, Jose, Guillermo
发明人： HARICHIAN, Bijan , MCMANUS, Richard, Loren , ROSA, Jose, Guillermo
IPC分类号： A61K8/41 , A61Q19/00 , A61Q1/02 , A61Q19/10 , A61Q5/02 , A61Q5/12 , A61Q15/00 , A61Q11/00
CPC分类号： A61Q19/08 , A61K8/416 , A61Q1/02 , A61Q5/02 , A61Q5/12 , A61Q11/00 , A61Q15/00 , A61Q19/00 , A61Q19/007 , A61Q19/10
摘要： A personal care product is provided which includes a composition containing dihydroxypropyltri(C1-C3 alkyl) ammonium salt in a carrier. The composition is packaged for delivery to a consumer and includes instructions printed on or associated with the packaging indicating topical use of the composition on skin, hair or the oral mucosae. Particularly useful is dihydroxypropyltrimonium chloride. The salt operates as a humectant to moisturize both at high and low relative humidity environments.
摘要翻译：提供了一种个人护理产品，其包括在载体中含有二羟丙基三（C 1 -C 3烷基）铵盐的组合物。将组合物包装以递送至消费者，并包括印刷在包装上或与包装有关的说明，指示组合物在皮肤，毛发或口腔粘膜上的局部使用。特别有用的是二羟丙基三甲基氯化铵。盐作为湿润剂在高低相对湿度环境下保湿。

9. 发明申请

WO2012013418A3 SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES 审中-公开
标题翻译：皮肤护理组合物包含取代的单体
公开(公告)号：WO2012013418A3
公开(公告)日：2012-08-23
申请号：PCT/EP2011059996
申请日：2011-06-16
申请人： UNILEVER PLC , UNILEVER NV , UNILEVER HINDUSTAN , ROSA JOSE GUILLERMO , HARICHIAN BIJAN , DRENNAN DIANA JEAN , BAJOR JOHN STEVEN , BOSKO CAROL ANNETTE
发明人： ROSA JOSE GUILLERMO , HARICHIAN BIJAN , DRENNAN DIANA JEAN , BAJOR JOHN STEVEN , BOSKO CAROL ANNETTE
IPC分类号： A61K8/41 , A61K31/137 , A61P17/00 , A61Q19/02 , C11D9/30
CPC分类号： A61K8/41 , A61K31/137 , A61K45/06 , A61Q1/02 , A61Q5/02 , A61Q15/00 , A61Q19/02 , A61Q19/10 , C11D9/30 , A61K2300/00
摘要： Skin care compositions comprising certain substituted phenethylamines, which are particularly beneficial for skin lightening and achieving evenness of color, especially for face and underarm skin. The compositions comprise 0.001% to 20% of a subtituted monoamine of structure (I) wherein R, is cyclohexyl, pheryl or mono - or di-substituted phenyl substituted by C1-C5 alkyl, C1-C5 alkoxy or phenoxy and R2 is hydrogen or methyl.
摘要翻译：包含某些取代的苯乙胺的皮肤护理组合物，其特别有利于皮肤发亮和实现颜色均匀，特别是对于面部和腋下皮肤。组合物包含0.001％至20％的结构（I）的取代的单胺，其中R 1为被C 1 -C 5烷基，C 1 -C 5烷氧基或苯氧基取代的环己基，苯基或单 - 或二取代苯基，R 2为氢或甲基。

10. 发明申请

WO2012013418A2 SKIN CARE COMPOSITIONS COMPRISING SUBSTITUTED MONOAMINES 审中-公开
标题翻译：皮肤护理组合物包含取代的单体
公开(公告)号：WO2012013418A2
公开(公告)日：2012-02-02
申请号：PCT/EP2011/059996
申请日：2011-06-16
申请人： UNILEVER PLC , UNILEVER N.V. , HINDUSTAN UNILEVER LIMITED , ROSA, Jose, Guillermo , HARICHIAN, Bijan , DRENNAN, Diana, Jean , BAJOR, John, Steven , BOSKO, Carol, Annette
发明人： ROSA, Jose, Guillermo , HARICHIAN, Bijan , DRENNAN, Diana, Jean , BAJOR, John, Steven , BOSKO, Carol, Annette
IPC分类号： A61Q19/02
CPC分类号： A61K8/41 , A61K31/137 , A61K45/06 , A61Q1/02 , A61Q5/02 , A61Q15/00 , A61Q19/02 , A61Q19/10 , C11D9/30 , A61K2300/00
摘要： Skin care compositions comprising certain substituted monoamines, which are particularly beneficial for skin lightening and achieving evenness of color, especially for face and underarm skin.
摘要翻译：包含某些取代的单胺的护肤组合物，其特别有利于减轻皮肤并实现颜色均匀，特别是对于面部和腋下皮肤。

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