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1. 发明申请

WO2006120635A2 HAIR-GROWTH CONTROL DEVICE AND HAIR-GROWTH CONTROL METHOD 审中-公开
标题翻译：头发生长控制装置和头发生长控制方法
公开(公告)号：WO2006120635A2
公开(公告)日：2006-11-16
申请号：PCT/IB2006/051438
申请日：2006-05-08
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VAN HAL, Robbert, A., M. , VERHAGEN, Rieko , ROOSEN, Guido , ROERSMA, Michiel, E.
发明人： VAN HAL, Robbert, A., M. , VERHAGEN, Rieko , ROOSEN, Guido , ROERSMA, Michiel, E.
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B18/20 , A61B2018/00452 , A61B2018/00476 , A61B2018/00904
摘要： The invention relates to a device (1) for hair-growth control of hairs (3), in particular hairs growing from human skin (5). The device (1) has a laser source (7) for generating a laser beam (9) during a pulse time, an optical system (15) for focusing the laser beam into a focal spot (25), and a laser beam manipulator (17) for positioning the focal spot in a target position. According to the invention, a dimension of the focal spot (25) and a power of the generated laser beam (9) are such that, in the focal spot (25), the laser beam has a power density which is above a characteristic threshold value for hair-growth related skin tissue above which, for the pulse time, a laser induced optical breakdown (LIOB) phenomenon occurs in the hair-growth related skin tissue. The LIOB phenomenon results in a number of mechanical effects, such as cavitation and the generation of shock waves, which damage the hair-growth related skin tissue in positions surrounding the LIOB phenomenon. An advantage of the device (1) according to the invention is that the amount of total energy which is necessary to cause trauma and induce (semi-)permanent cessation of hair-growth is at such a level that irritation and damage of the surrounding skin tissue is very limited or even completely prevented.
摘要翻译：本发明涉及一种用于毛发（3）的毛发生长控制的装置（1），特别是从人体皮肤生长的毛发（5）。设备（1）具有用于在脉冲时间期间产生激光束（9）的激光源（7），用于将激光束聚焦到焦斑（25）中的光学系统（15）和激光束操纵器 17），用于将焦点定位在目标位置。根据本发明，焦点（25）的尺寸和所产生的激光束（9）的功率使得在焦点（25）中，激光束的功率密度高于特征阈值对于毛发生长相关的皮肤组织，其中在脉冲时间，在毛发生长相关的皮肤组织中发生激光诱导的光学破坏（LIOB）现象。 LIOB现象导致许多机械效应，例如气蚀和产生冲击波，其损害围绕LIOB现象的位置的毛发生长相关的皮肤组织。根据本发明的装置（1）的优点在于，引起创伤和引发（半）永久性头发生长停止所需的总能量的量处于使周围皮肤发生刺激和损伤的程度组织非常有限或甚至完全防止。

2. 发明申请

WO2005016453A1 DEVICE AND METHOD FOR LOW INTENSITY OPTICAL HAIR GROWTH CONTROL 审中-公开
标题翻译：低强度光学头发生长控制的装置和方法
公开(公告)号：WO2005016453A1
公开(公告)日：2005-02-24
申请号：PCT/IB2004/051395
申请日：2004-08-05
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , ROERSMA, Michiel, E. , NUIJS, Antonius, M. , ROOSEN, Guido, F.
发明人： ROERSMA, Michiel, E. , NUIJS, Antonius, M. , ROOSEN, Guido, F.
IPC分类号： A61N5/06
CPC分类号： A61N5/0617 , A61B18/203 , A61B2018/00452 , A61B2018/00476 , A61B2018/1807 , A61N2005/0659
摘要： The present invention discloses a method for controlling growth of hair on human skin with low doses of electromagnetic radiation, and a device (1) for carrying out the method. In the method, radiation (13) of a suitable spectrum is applied to the skin (12), in one or more pulses of between 1 and 100 ms, and with maximum fluencies on the skin between 1 and 12 J/cm2. By applying such low fluencies and at controlled pulse durations, follicles of the hairs are induced to the catagen phase. This means that the growth of the hairs of those follicles will stop. Although the method is not primarily aimed at immediate hair removal, hairs may be shed subsequently. In any case, further growth may be stopped for prolonged periods of time. The main advantage of the method is that the risk of damage to the skin is minimized.
摘要翻译：本发明公开了一种用低剂量电磁辐射控制人皮上毛发生长的方法，以及用于实施该方法的装置（1）。在该方法中，适当光谱的辐射（13）以1至100ms的一个或多个脉冲施加到皮肤（12），并且在皮肤上的最大流量在1至12J / cm 2之间。通过应用这样低的流量和在受控的脉冲持续时间，毛发的毛囊被诱导到引导阶段。这意味着那些毛囊的毛发生长会停止。虽然该方法不是主要针对立即脱毛，但毛发可以随后脱落。无论如何，进一步的增长可能会延长一段时间。该方法的主要优点是减少对皮肤损伤的风险。

3. 发明申请

WO2008050261A1 AN OPTICAL TREATMENT SYSTEM AND AN ADJUSTMENT MEMBER THEREFOR 审中-公开
标题翻译：光学处理系统及其调整成员
公开(公告)号：WO2008050261A1
公开(公告)日：2008-05-02
申请号：PCT/IB2007/054212
申请日：2007-10-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , FERTNER, Rembert , ROOSEN, Guido
发明人： FERTNER, Rembert , ROOSEN, Guido
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B18/20 , A61B90/90 , A61B90/96 , A61B90/98 , A61B2018/00023 , A61B2018/00452 , A61B2018/00636 , A61B2018/1807 , A61B2018/2035
摘要： The invention provides an optical treatment system comprising a first optical window (20), a light source (14), a control unit (18) for controlling the light source (14) such that optical radiation at the first optical window (20) has at least one optical parameter with a predetermined first value, and comprising at least one transmitting adjustment member (30) having a second optical window (34) and being positionable such that optical radiation is emittable via the second optical window (34), said optical treatment system further comprising an optical parameter control means (36, 38; 42; 46, 48, 50; 52; 54) that is arranged to control said at least one optical parameter to have a predetermined second value at the second optical window (34). The optical parameter control means may be active, and influence the control unit (18) or light source (14), and/or passive, and influence the radiation emitted through the first optical window (20) by filtering, reflection, absorption, etc. Thus, the system is able to provide radiation having well known, predetermined and thus more reliable properties, even if the second window has a different shape or area or the radiation has been influenced otherwise.
摘要翻译：本发明提供了一种光学处理系统，其包括第一光学窗口（20），光源（14），用于控制光源（14）的控制单元（18），使得第一光学窗口（20）处的光学辐射具有具有预定第一值的至少一个光学参数，并且包括具有第二光学窗口（34）的至少一个透射调节构件（30），并且可定位成使得光学辐射经由第二光学窗口（34）发射，所述光学处理系统还包括光学参数控制装置（36,38; 42; 46,48,50; 52; 54），其布置成控制所述至少一个光学参数在第二光学窗口（34）处具有预定的第二值）。光学参数控制装置可以是有效的并且影响控制单元（18）或光源（14）和/或被动，并且通过滤波，反射，吸收等影响通过第一光学窗口（20）发射的辐射因此，即使第二窗口具有不同的形状或面积，或辐射也受到其他影响，系统能够提供具有公知的，预定的，因此更可靠的性质的辐射。

4. 发明申请

WO2008001284A3 DEVICE AND METHOD FOR THE TREATMENT OF SKIN, AND USE OF THE DEVICE 审中-公开
公开(公告)号：WO2008001284A3
公开(公告)日：2008-01-03
申请号：PCT/IB2007/052399
申请日：2007-06-21
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , VERHAGEN, Rieko , VAN HAL, Robbert, A., M. , GOTTENBOS, Bart , JANSSEN, Jozef, J., M. , ACKERMANS, Paul, A., J. , MORALES SERRANO, Francisco , NEERKEN, Sieglinde , BROKKEN, Dirk , ROOSEN, Guido
发明人： VERHAGEN, Rieko , VAN HAL, Robbert, A., M. , GOTTENBOS, Bart , JANSSEN, Jozef, J., M. , ACKERMANS, Paul, A., J. , MORALES SERRANO, Francisco , NEERKEN, Sieglinde , BROKKEN, Dirk , ROOSEN, Guido
IPC分类号： A61B18/20
摘要： The invention provides a skin treatment device comprising a laser source (40) and focusing optics (50), such that a focal spot (18) is positioned in a dermis layer (24) of the skin to be treated. The laser beam (42) is powered and focused (16) such that a LIOB (laser induced optical breakdown) phenomenon is obtained, which affects the skin in order to stimulate re-growth of tissue. This in turn reduces wrinkles (30). The device may comprise wrinkle-determining means (52, 54, 56, 58). The focusing optics (50) may have a numerical aperture of at least 0.4. The invention also provides a corresponding method to treat skin, in particular to reduce wrinkles (30), by providing a focused laser beam (16) that causes LIOB in the dermis layer (24) of the skin. The advantage is that damage to overlaying epidermis layers may be avoided by the use of the very local LIOB phenomenon.

5. 发明申请

WO2006120635A3 HAIR-GROWTH CONTROL DEVICE AND HAIR-GROWTH CONTROL METHOD 审中-公开
标题翻译：头发生长控制装置和头发生长控制方法
公开(公告)号：WO2006120635A3
公开(公告)日：2007-02-15
申请号：PCT/IB2006051438
申请日：2006-05-08
申请人： KONINKL PHILIPS ELECTRONICS NV , VAN HAL ROBBERT A M , VERHAGEN RIEKO , ROOSEN GUIDO , ROERSMA MICHIEL E
发明人： VAN HAL ROBBERT A M , VERHAGEN RIEKO , ROOSEN GUIDO , ROERSMA MICHIEL E
IPC分类号： A61B18/20
CPC分类号： A61B18/203 , A61B18/20 , A61B2018/00452 , A61B2018/00476 , A61B2018/00904
摘要： The invention relates to a device (1) for hair-growth control of hairs (3), in particular hairs growing from human skin (5). The device (1) has a laser source (7) for generating a laser beam (9) during a pulse time, an optical system (15) for focusing the laser beam into a focal spot (25), and a laser beam manipulator (17) for positioning the focal spot in a target position. According to the invention, a dimension of the focal spot (25) and a power of the generated laser beam (9) are such that, in the focal spot (25), the laser beam has a power density which is above a characteristic threshold value for hair-growth related skin tissue above which, for the pulse time, a laser induced optical breakdown (LIOB) phenomenon occurs in the hair-growth related skin tissue. The LIOB phenomenon results in a number of mechanical effects, such as cavitation and the generation of shock waves, which damage the hair-growth related skin tissue in positions surrounding the LIOB phenomenon. An advantage of the device (1) according to the invention is that the amount of total energy which is necessary to cause trauma and induce (semi-)permanent cessation of hair-growth is at such a level that irritation and damage of the surrounding skin tissue is very limited or even completely prevented.
摘要翻译：本发明涉及一种用于毛发（3）的毛发生长控制的装置（1），特别是从人体皮肤生长的毛发（5）。设备（1）具有用于在脉冲时间期间产生激光束（9）的激光源（7），用于将激光束聚焦到焦斑（25）中的光学系统（15）和激光束操纵器 17），用于将焦点定位在目标位置。根据本发明，焦点（25）的尺寸和所产生的激光束（9）的功率使得在焦点（25）中，激光束的功率密度高于特征阈值对于毛发生长相关的皮肤组织，其中在脉冲时间，在毛发生长相关的皮肤组织中发生激光诱导的光学破坏（LIOB）现象。 LIOB现象导致许多机械效应，例如气蚀和产生冲击波，其损害围绕LIOB现象的位置的毛发生长相关的皮肤组织。根据本发明的装置（1）的优点在于，引起创伤和引发（半）永久性头发生长停止所需的总能量的量处于使周围皮肤发生刺激和损伤的程度组织非常有限或甚至完全防止。

6. 发明申请

WO2008001284A2 DEVICE AND METHOD FOR THE TREATMENT OF SKIN, AND USE OF THE DEVICE 审中-公开
标题翻译：用于治疗皮肤的装置和方法以及装置的使用
公开(公告)号：WO2008001284A2
公开(公告)日：2008-01-03
申请号：PCT/IB2007052399
申请日：2007-06-21
申请人： KONINKL PHILIPS ELECTRONICS NV , VERHAGEN RIEKO , VAN HAL ROBBERT A M , GOTTENBOS BART , JANSSEN JOZEF J M , ACKERMANS PAUL A J , MORALES SERRANO FRANCISCO , NEERKEN SIEGLINDE , BROKKEN DIRK , ROOSEN GUIDO
发明人： VERHAGEN RIEKO , VAN HAL ROBBERT A M , GOTTENBOS BART , JANSSEN JOZEF J M , ACKERMANS PAUL A J , MORALES SERRANO FRANCISCO , NEERKEN SIEGLINDE , BROKKEN DIRK , ROOSEN GUIDO
CPC分类号： A61B18/203 , A61B5/1077 , A61B5/442 , A61B18/20 , A61B90/361 , A61B2017/00057 , A61B2017/00106 , A61B2017/00154 , A61B2018/00452 , A61B2018/0047 , A61B2018/00666 , A61B2018/00904 , A61B2018/20351
摘要： The invention provides a skin treatment device comprising a laser source (40) and focusing optics (50), such that a focal spot (18) is positioned in a dermis layer (24) of the skin to be treated. The laser beam (42) is powered and focused (16) such that a LIOB (laser induced optical breakdown) phenomenon is obtained, which affects the skin in order to stimulate re-growth of tissue. This in turn reduces wrinkles (30). The device may comprise wrinkle-determining means (52, 54, 56, 58). The focusing optics (50) may have a numerical aperture of at least 0.4. The invention also provides a corresponding method to treat skin, in particular to reduce wrinkles (30), by providing a focused laser beam (16) that causes LIOB in the dermis layer (24) of the skin. The advantage is that damage to overlaying epidermis layers may be avoided by the use of the very local LIOB phenomenon.
摘要翻译：本发明提供一种皮肤治疗装置，其包括激光源（40）和聚焦光学元件（50），使得焦点（18）位于待治疗皮肤的真皮层（24）中。激光束（42）被供电并聚焦（16），使得获得LIOB（激光诱导光学击穿）现象，其影响皮肤以刺激组织的再生长。这反过来又减少皱纹（30）。该装置可以包括皱纹确定装置（52,54,56,58）。聚焦光学元件（50）可以具有至少0.4的数值孔径。本发明还提供了一种相应的治疗皮肤的方法，特别是通过提供在皮肤真皮层（24）中引起LIOB的聚焦激光束（16）来减少皱纹（30）。优点是可以通过使用非常局部的LIOB现象来避免覆盖表皮层的损伤。

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