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    • 3. 发明申请
    • MULTI-LOCATION POSTURE SENSING
    • 多位置姿态感知
    • WO2008137306A1
    • 2008-11-13
    • PCT/US2008/061100
    • 2008-04-22
    • MEDTRONIC, INC.GERBER, Martin T.RONDONI, John C.
    • GERBER, Martin T.RONDONI, John C.
    • A61N1/36
    • A61N1/36135A61N1/0551A61N1/36514A61N1/36535A61N1/36542
    • Techniques for controlling therapy delivery based on the relative orientation and/or motion of a device accelerometer and a lead accelerometer are described. In one embodiment, a therapy system includes an electrical stimulator and a lead. The electrical stimulator comprises a processor that controls delivery of a therapy to a target stimulation site in a patient and a device accelerometer coupled to the electrical stimulator. The lead is coupled to the electrical stimulator to deliver the therapy from the electrical stimulator to the target stimulation site in the patient, and includes a lead accelerometer. The processor compares signals from the accelerometers, and controls delivery of the therapy to the patient based on the comparison. In this manner, the processor may adjust stimulation to, for example, address movement of electrodes relative to target tissue when a patient changes postures.
    • 描述了基于设备加速度计和线加速度计的相对取向和/或运动来控制治疗递送的技术。 在一个实施例中,治疗系统包括电刺激器和引线。 电刺激器包括处理器,其控制对患者的目标刺激部位的治疗传递和耦合到电刺激器的装置加速度计。 引线耦合到电刺激器以将治疗从电刺激器传递到患者中的目标刺激部位,并且包括引线加速度计。 处理器比较来自加速度计的信号,并且基于比较来控制对患者的治疗传递。 以这种方式,当患者改变姿势时,处理器可以将刺激调整为例如电极相对于靶组织的地址移动。
    • 6. 发明申请
    • PATIENT-INDIVIDUALIZED EFFICACY RATING
    • 患者个性化效能评分
    • WO2007130173A1
    • 2007-11-15
    • PCT/US2007/001940
    • 2007-01-25
    • MEDTRONIC, INC.GERBER, Martin, T.RONDONI, John, C.
    • GERBER, Martin, T.RONDONI, John, C.
    • A61N1/372G06F19/00
    • A61N1/37247G16H50/50
    • The disclosure is directed to techniques for providing a patient- individualized efficacy rating. Different stimulation parameters impact efficacy. For example, efficacy may be a function of parameters such as electrode combination, stimulation amplitude, pulse width, and pulse rate. Efficacy may vary from patient-to-patient. For example, efficacy may vary according to age, gender, physiology, disease state, activity level, or activity profile. Comparable stimulation programs may provide' different efficacy levels for different patients, according to patient characteristics or desires. Patients may rank efficacy parameters differently. The efficacy parameters may include desirable therapeutic effects and undesirable side effects. For one patient, optimization of a particular efficacy parameter may be the paramount concern. Other patients may be willing to compromise the outcome of the same parameter in favor of better outcomes with other efficacy parameters. A patient-individualized efficacy rating permits a patient and clinician to customize efficacy evaluation according to the patient's condition or needs.
    • 本公开涉及用于提供患者个体化功效评级的技术。 不同刺激参数影响疗效。 例如,功效可以是诸如电极组合,刺激幅度,脉冲宽度和脉率之类的参数的函数。 疗效可能因患者而异。 例如,功效可以根据年龄,性别,生理,疾病状态,活动水平或活动情况而变化。 可比较的刺激方案可以根据患者的特征或欲望为不同的患者提供不同的功效水平。 患者可以不同地对功效参数进行排序。 功效参数可以包括期望的治疗效果和不期望的副作用。 对于一个患者,特定功效参数的优化可能是至关重要的。 其他患者可能愿意危及相同参数的结果,有利于其他功效参数的更好结局。 患者个性化的功效评级允许患者和临床医生根据患者的状况或需要定制功效评估。
    • 7. 发明申请
    • TREE-BASED ELECTRICAL STIMULATOR PROGRAMMING FOR PAIN THERAPY
    • 用于疼痛治疗的基于TREE的电刺激器编程
    • WO2007127455A2
    • 2007-11-08
    • PCT/US2007/010381
    • 2007-04-30
    • MEDTRONIC, INC.GERBER, Martin, T.RONDONI, John, C.
    • GERBER, Martin, T.RONDONI, John, C.
    • A61N1/36071A61N1/37247G06F19/00
    • The disclosure describes an implantable stimulation system that guides programming with a therapeutic tree. All possible stimulation parameters are arranged on the therapeutic tree, with each level of the therapeutic tree containing a different stimulation parameter type. Each level includes nodes that are connected to nodes of adjacent levels. A program path is created by moving through nodes of lower levels. The stimulation parameter types are arranged so that coarse adjustments occur at higher levels of the tree and fine adjustments occur at lower levels of the tree. The nodes of the program path define the stimulation parameters of the delivered stimulation therapy. The user may provide information such as efficacy input and/or medication dosage information to the system for identifying the most efficacious program path in treating pain of the patient. Additionally or alternatively, efficacy feedback may be received from physiological parameter sensors.
    • 本公开描述了一种用治疗树引导编程的可植入刺激系统。 所有可能的刺激参数被布置在治疗树上,治疗树的每个水平含有不同的刺激参数类型。 每个级别包括连接到相邻级别的节点的节点。 通过移动较低级别的节点创建程序路径。 刺激参数类型被布置为使得在较高级别的树上进行粗调,并且在较低级别处发生精细调整。 程序路径的节点定义了递送的刺激疗法的刺激参数。 用户可以向系统提供诸如功效输入和/或药物剂量信息的信息,以识别治疗患者疼痛的最有效的程序路径。 附加地或替代地,可以从生理参数传感器接收功效反馈。