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1. 发明申请

WO1992010293A1 DISPENSER 审中-公开
标题翻译：饮水机
公开(公告)号：WO1992010293A1
公开(公告)日：1992-06-25
申请号：PCT/GB1991002161
申请日：1991-12-05
申请人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. , ROBINSON, Grenville, Arthur , ATTRIDGE, John, Worthington
发明人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
IPC分类号： B01L03/02
CPC分类号： B01L3/0265 , B01L3/0262 , G01N2035/1023
摘要： A method for delivering controlled amounts of reagent, which involves the use of a device comprising a nozzle through which the reagent is able to flow and a reservoir for the reagent, the reservoir being connected to a nozzle, with a ball valve between the nozzle and reservoir to accurately regulate the flow of reagent. Such a method allows the accurate and reproducible delivery of reagents such as biochemical reagents.
摘要翻译：一种用于输送受控量的试剂的方法，其包括使用包括试剂能够流过的喷嘴的装置和用于试剂的储存器，储存器连接到喷嘴，在喷嘴和喷嘴之间具有球阀水库精确调节试剂的流动。这种方法允许准确和可重复地递送诸如生物化学试剂的试剂。

2. 发明申请

WO1997046203A1 RECONSTITUTING DEVICE FOR INJECTABLE MEDICATION 审中-公开
标题翻译：用于注射药物的重新配置装置
公开(公告)号：WO1997046203A1
公开(公告)日：1997-12-11
申请号：PCT/GB1997001492
申请日：1997-06-03
申请人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. , ROBINSON, Grenville, Arthur , HOBBS, Michael, Anthony , ROWLANDS, Martyn, Omar , CALVERT, John, Richard
发明人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
IPC分类号： A61J01/00
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2013 , A61J1/2051 , A61J1/2065 , A61J1/2089
摘要： A device for reconstituting liquid for medical use by bringing together a first liquid medium contained in a first vessel in the form of a cartridge (3) and a second medium, such as a drug in solid form, contained in a second vessel in the form of a vial (7), the device (19) comprising means (41) for supporting the first and second vessels, and a movable operating member (50) for applying a force to cause the first liquid medium to be delivered at a controlled rate from the first vessel into the second vessel. The first and second vessels may be provided in a pack (70) having liquid transfer means in the form of a needle (10).
摘要翻译：通过将包含在第一容器中的第一容器中的第一液体介质与固体形式的第二介质（例如固体形式的药物）接合在一起的第二容器中，形成用于医疗用液体的装置（7），所述装置（19）包括用于支撑第一和第二容器的装置（41）和用于施加力以使受控速率输送第一液体介质的力的可移动操作构件（50）从第一艘船进入第二艘船。第一和第二容器可以设置在具有针（10）形式的液体转移装置的包装（70）中。

3. 发明申请

WO1995024632A1 SPECTROPHOTOMETRIC TECHNIQUES 审中-公开
标题翻译：分光光度法
公开(公告)号：WO1995024632A1
公开(公告)日：1995-09-14
申请号：PCT/GB1995000507
申请日：1995-03-09
申请人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. , ROBINSON, Grenville, Arthur , COOKSON, Alan, Derek
发明人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
IPC分类号： G01N21/03
CPC分类号： G01N21/0303 , B01L3/502715 , B01L2300/0822 , B01L2300/168 , B01L2400/0406
摘要： The use as a cuvette in spectrophotometric assays of a sample-collecting device is disclosed, the said device possessing a cavity or cavities each having a dimension small enough to enable sample liquid to be drawn into the cavity by capillary action, wherein a surface of the cavity is a surface of a transparent solid plate having a substantially rectangular cross section and forming a wall of the cavity, the opposite surface of the cavity being an additional structure having a substantially rectangular cross section and forming a wall of the cavity, and wherein a portion of said plate carries a reflective coating and a portion of said additional structure is reflective.
摘要翻译：公开了用作样品收集装置的分光光度测定法中的比色杯，所述装置具有空腔或空腔，每个腔或腔具有足够小的尺寸，以使样品液体能够通过毛细管作用被吸入空腔中，其中，空腔是透明固体板的表面，其具有基本上矩形的横截面并且形成空腔的壁，空腔的相对表面是具有基本矩形横截面并形成空腔壁的附加结构，并且其中所述板的部分承载反射涂层，并且所述附加结构的一部分是反射性的。

4. 发明申请

WO1992009892A1 METHOD OF ASSAY 审中-公开
标题翻译：测定方法
公开(公告)号：WO1992009892A1
公开(公告)日：1992-06-11
申请号：PCT/GB1991002058
申请日：1991-11-21
申请人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. , ATTRIDGE, John, Worthington , DEACON, Julie, Karen , DANIELS, Phelim, Brinley , LOVE, Colin, Andrew , ROBINSON, Grenville, Arthur , THOMSON, Aileen, Margaret
发明人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
IPC分类号： G01N33/543
CPC分类号： G01N33/54366
摘要： A method of assay for a ligand in a sample is described in which calibration occurs within the assay. This is achieved utilising a measurement region and one or more calibration regions. In at least one of the calibration regions a non-zero signal results, either because of the presence of a calibration reagent or as a result of a binding reaction analagous to that which takes place in the measurement region.
摘要翻译：描述了测定样品中配体的方法，其中在测定中进行校准。这是利用测量区域和一个或多个校准区域实现的。在至少一个校准区域中，由于校准试剂的存在或与在测量区域发生的结合反应的结合反应的结果，导致非零信号。

5. 发明申请

WO1995016914A1 SENSOR DEVICE FOR SANDWICH ASSAY 审中-公开
标题翻译： SANDWICH测量传感器设备
公开(公告)号：WO1995016914A1
公开(公告)日：1995-06-22
申请号：PCT/GB1994002741
申请日：1994-12-15
申请人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. , ROBINSON, Grenville, Arthur , FLETCHER, Janys
发明人： APPLIED RESEARCH SYSTEMS ARS HOLDING N.V.
IPC分类号： G01N33/543
CPC分类号： G01N33/54373 , Y10S435/808 , Y10S436/805
摘要： Sensor devices for use in assaying for a ligand in a sample are described, the devices comprising: i) a discrete zone ("the measurement zone") on a region of which ("the measurement region") is immobilised directly or indirectly a first specific binding partner for the ligand under assay (or a reagent precomplexed with or capable of forming a complex with a specific binding partner for the ligand under assay), which zone additionally contains, in releasable form, a first known amount of an optionally labelled second specific binding partner for the ligand under assay, the second specific binding partner being directed to an epitope of the ligand under assay different to the epitope to which the first specific binding partner is directed; and ii) a second discrete zone ("the reference zone") on a region of which is immobilised directly or indirectly a first specific binding partner for the ligand under assay (or a reagent precomplexed with or capable of forming a complex with a specific binding partner for the ligand under assay), which zone additionally contains, in releasable form, a known amount of ligand analogue and separately contains, in releasable form, a second known amount of an optionally labelled second specific binding partner for the ligand under assay as defined above, said second known amount being less than the aforementioned first known amount in the measurement zone. Methods of sandwich assay using such devices are also described.
摘要翻译：描述了用于测定样品中配体的传感器装置，所述装置包括：i）在其区域（“测量区域”）上的离散区域（“测量区域”）直接或间接地固定在第一（或与分析中的配体的特异性结合配偶体复合或能够形成复合物的试剂的特异性结合配偶体），该区域以可释放形式另外含有第一已知量的任选标记的第二在测定下配体的特异性结合配偶体，第二特异性结合配偶体被引导到与第一特异性结合配偶体所针对的表位不同的测定下的配体的表位; 和ii）第二离散区（“参考区”），其区域直接或间接地固定在测定下的配体的第一特异性结合配偶体（或与预定复合物或能够形成具有特异性结合的复合物的试剂配体在测定中），该区域另外含有已知量的配体类似物，并且以可释放的形式另外含有第二已知量的用于所测定的配体的任选标记的第二特异性结合配偶体，定义如下所述第二已知量小于测量区中的上述第一已知量。还描述了使用这种装置的夹心测定方法。

6. 发明申请

WO1989011655A1 METHOD OF ASSAY 审中-公开
标题翻译：测定方法
公开(公告)号：WO1989011655A1
公开(公告)日：1989-11-30
申请号：PCT/GB1989000568
申请日：1989-05-23
申请人： ARES-SERONO RESEARCH & DEVELOPMENT LIMITED ... , ALLEN, Gerald, John , DENYER, Madlyn, Delveda , ROBINSON, Grenville, Arthur
发明人： ARES-SERONO RESEARCH & DEVELOPMENT LIMITED ...
IPC分类号： G01N33/53
CPC分类号： G01N33/76 , G01N33/53 , G01N33/581 , G01N33/74 , G01N33/96 , G01N2333/5756 , Y10S435/975 , Y10S436/815 , Y10S436/817
摘要： The invention relates to a method of assaying for a ligand in a sample which incorporates a non-antigen calibrator. This provides particular advantages when the antigen which it is desired to assay is unstable in liquid form. The invention also relates to a kit for carrying out a method of assay according to the invention.

7. 发明申请

WO2007072009A2 CONTAINER WITH RFID DEVICE FOR STORING TEST SENSORS 审中-公开
标题翻译：具有用于存储测试传感器的RFID设备的容器
公开(公告)号：WO2007072009A2
公开(公告)日：2007-06-28
申请号：PCT/GB2006/004843
申请日：2006-12-21
申请人： LIFESCAN SCOTLAND, LTD , ROBINSON, Grenville , MCINULTY, John , BASKEYFIELD, Damien , O'REILLY, Tom
发明人： ROBINSON, Grenville , MCINULTY, John , BASKEYFIELD, Damien , O'REILLY, Tom
IPC分类号： G01N33/48
CPC分类号： G01N33/48771 , G01N33/48778
摘要： The subject invention relates to containers provided with RFID devices for storing test strips.
摘要翻译：本发明涉及具有用于存储测试条的RFID装置的容器。

8. 发明申请

WO2006026748A1 METHOD OF MANUFACTURING AN AUTO-CALIBRATING SENSOR 审中-公开
标题翻译：制造自动校准传感器的方法
公开(公告)号：WO2006026748A1
公开(公告)日：2006-03-09
申请号：PCT/US2005/031286
申请日：2005-08-31
申请人： LIFESCAN SCOTLAND LIMITED , MCCLUSKEY, Joseph , GRIFFITH, Alun , ROBINSON, Grenville , SPALDING, Gordon , TAYLOR, David , BECK, Erica, Mary
发明人： MCCLUSKEY, Joseph , GRIFFITH, Alun , ROBINSON, Grenville , SPALDING, Gordon , TAYLOR, David , BECK, Erica, Mary
IPC分类号： G01N33/487 , G01N33/58 , G01N27/416 , A61B5/00 , A61K49/00
CPC分类号： A61B5/14865 , A61B5/0022 , A61B5/14514 , A61B5/14532 , A61B5/150022 , A61B5/150068 , A61B5/150083 , A61B5/150175 , A61B5/150358 , A61B5/150412 , A61B5/150503 , A61B5/150526 , A61B5/150793 , A61B5/15087 , A61B5/151 , A61B5/15186 , A61B5/155 , A61B5/157 , A61B2562/085 , A61K47/6957 , A61M5/1723 , G06F19/00 , G06F19/3418 , G06F19/3456 , G16H40/63
摘要： The invention concerns a sensor that, when exposed to a fluid, develops a measurable characteristic that is a function of the level of an analyte in the fluid and of a calibration quantity of the sensor. A calibration quantity is some physical, chemical or other inherent property that the sensor possesses that affects its response to the analyte. The sensor includes an RFID tag that receives, stores and conveys information representing the calibration quantity. The wireless device is incorporated into or attached to the sensor during the manufacturing process and before the sensor is calibrated. The wireless device can be written wirelessly once the calibration has been done. This does not involve any additional handling of the sensor and can be done once the sensor has been placed into a protective enclosure. Because of this, the process of wirelessly transmitting the calibration information to the wireless device does not alter any pre-existing calibration quantities and neither does it introduce any new calibration quantities, thus preserving the calibration of the sensor even though the sensor has been wirelessly modified to carry information representing its calibration quantity.
摘要翻译：本发明涉及一种传感器，其在暴露于流体时产生可测量的特性，其是流体中分析物的水平和传感器的校准量的函数。校准量是传感器拥有的影响其对分析物的响应的一些物理，化学或其他固有性质。传感器包括接收，存储和传送表示校准量的信息的RFID标签。无线设备在制造过程中并且在传感器被校准之前被结合到传感器中或附接到传感器。一旦校准完成，无线设备就可以无线地写入。这不涉及传感器的任何额外的处理，并且一旦将传感器放置到保护外壳中就可以进行。因此，将校准信息无线发送到无线设备的过程不会改变任何预先存在的校准量，并且也不会引入任何新的校准量，因此即使传感器已被无线地修改也能保持传感器的校准携带表示其校准量的信息。

9. 发明申请

WO1993025892A1 SENSOR FOR OPTICAL ASSAY 审中-公开
标题翻译：传感器进行光学测量
公开(公告)号：WO1993025892A1
公开(公告)日：1993-12-23
申请号：PCT/GB1993001216
申请日：1993-06-09
申请人： ARS HOLDING 89 N.V. , ATTRIDGE, John, Worthington , ROBINSON, Grenville, Arthur
发明人： ARS HOLDING 89 N.V.
IPC分类号： G01N21/77
CPC分类号： G01N21/7703 , C12Q1/001 , G01N2021/757
摘要： Sensor devices for use in assaying for a substance selected from (i) enzymes capable of producing a change in their environment as a result of catalytic reaction with a substrate and (ii) substrates for such enzymes is described, the devices comprising an optical waveguide having immobilised directly or indirectly on a discrete region ("the measurement region") of one longitudinal surface thereof a species whose optical properties change as a result of the aforementioned change in its environment together with the member of an enzyme substrate/enzyme pair complementary to the substance under assay. Methods of assay using such devices are also described.
摘要翻译：传感器装置用于测定选自以下的物质：（i）由于与底物的催化反应而能够产生其环境变化的酶和（ii）这些酶的底物，所述装置包括具有直接或间接地固定在其一个纵向表面的离散区域（“测量区域”）上，其光学性质随着其环境的变化与酶底物/酶对的成员一起变化，物质在测定。还描述了使用这种装置的测定方法。

10. 发明申请

WO2007072009A3 CONTAINER WITH RFID DEVICE FOR STORING TEST SENSORS 审中-公开
标题翻译：具有用于存储测试传感器的RFID设备的容器
公开(公告)号：WO2007072009A3
公开(公告)日：2007-11-29
申请号：PCT/GB2006004843
申请日：2006-12-21
申请人： LIFESCAN SCOTLAND LTD , ROBINSON GRENVILLE , MCINULTY JOHN , BASKEYFIELD DAMIEN , O'REILLY TOM
发明人： ROBINSON GRENVILLE , MCINULTY JOHN , BASKEYFIELD DAMIEN , O'REILLY TOM
IPC分类号： G01N33/48
CPC分类号： G01N33/48771 , G01N33/48778
摘要： The subject invention relates to containers provided with RFID devices for storing test strips, wherein the RFID device is located between the outermost surface and the innermost surface of the container.
摘要翻译：本发明涉及设置有用于存储测试条的RFID装置的容器，其中RFID装置位于容器的最外表面和最内表面之间。

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