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1. 发明公开

EP1592367A4 METHOD AND DEVICE FOR TREATING DISEASED VALVE 有权
标题翻译：方法和装置治疗患病FOLD
公开(公告)号：EP1592367A4
公开(公告)日：2010-12-01
申请号：EP03749171
申请日：2003-08-28
申请人： HEART LEAFLET TECHNOLOGIES , WILSON ROBERT FOSTER
发明人： WILSON ROBERT FOSTER
IPC分类号： A61B17/32 , A61F20060101 , A61F2/24
CPC分类号： A61F2/2418 , A61F2/2427 , A61F2/2463 , A61F2/2466 , Y10S623/904
摘要： A device and method for improving flow through a native blood vessel valve, such as the aortic valve, are provided. The present invention allows a miniature valve to be implanted into affected leaflets percutaneously, obviating the need for coronary bypass surgery. The method includes the cutting of small holes, on the order of 4 mm, in the leaflets of a targeted valve, thereby allowing blood to flow through the newly formed holes. The holes are used as attachment sites for the miniature valves of the present invention.

2. 发明公开

EP1592367A2 METHOD AND DEVICE FOR TREATING DISEASED VALVE 有权
标题翻译：方法和装置治疗患病FOLD
公开(公告)号：EP1592367A2
公开(公告)日：2005-11-09
申请号：EP03749171.9
申请日：2003-08-28
申请人： Heart Leaflet Technologies , Wilson, Robert Foster
发明人： WILSON, Robert, Foster
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2427 , A61F2/2463 , A61F2/2466 , Y10S623/904
摘要： A device and method for improving flow through a native blood vessel valve, such as the aortic valve, are provided. The present invention allows a miniature valve to be implanted into affected leaflets percutaneously, obviating the need for coronary bypass surgery. The method includes the cutting of small holes, on the order of 4 mm, in the leaflets of a targeted valve, thereby allowing blood to flow through the newly formed holes. The holes are used as attachment sites for the miniature valves of the present invention.

3. 发明申请

WO2011143263A2 STENTLESS SUPPORT STRUCTURE 审中-公开
标题翻译：坚固的支持结构
公开(公告)号：WO2011143263A2
公开(公告)日：2011-11-17
申请号：PCT/US2011/035983
申请日：2011-05-10
申请人： HEART LEAFLET TECHNOLOGIES, INC. , GAINOR, John , THILL, Gary, A. , WILSON, Robert, Foster , BANICK, Christopher, M.
发明人： GAINOR, John , THILL, Gary, A. , WILSON, Robert, Foster , BANICK, Christopher, M.
IPC分类号： A61M25/01
CPC分类号： A61F2/2427 , A61F2/2418 , A61F2/2436 , A61F2/2445 , A61F2/2466 , A61F2/90 , A61F2/95 , A61F2210/0076 , A61F2230/0067
摘要： A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.
摘要翻译：能够至少部分地组装在原位的无支架支架结构。支撑结构包括非常柔性的编织管，并且当细长时，变得非常长并且直径非常小，从而能够放置在小直径导管内。支撑结构优选地由一种或多种超弹性或形状记忆材料（例如镍钛诺）的细股构成。当从导管释放时，支撑结构将其自身折叠成纵向紧凑的构造。随着折叠数量的增加，支撑结构因此获得显着的强度。这种径向强度消除了对支撑支架的需要。支撑结构可以包括用于人造瓣膜的附接点。

4. 发明申请

WO2006128185A3 INTRAVASCULAR CUFF 审中-公开
标题翻译：血管内镜
公开(公告)号：WO2006128185A3
公开(公告)日：2007-04-05
申请号：PCT/US2006020975
申请日：2006-05-30
申请人： HEART LEAFLET TECHNOLOGIES INC , WILSON ROBERT FOSTER , GAINOR JOHN
发明人： WILSON ROBERT FOSTER , GAINOR JOHN
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/07 , A61F2/2475 , A61F2/844 , A61F2002/302 , A61F2002/30604 , A61F2230/0065 , A61F2230/0078 , A61F2250/0003 , A61F2250/0039 , A61F2250/006
摘要： An intravascular cuff acts as a lining between a native vessel and an intravascular prosthetic device. During deployment, the ends of the cuff curl back upon themselves and are capable of trapping native tissue, such as valve leaflet tissue, between the ends. The cuff creates a seal between the vessel and the prosthetic, thereby preventing leakage around the prosthetic. The cuff also traps any embolic material dislodged from the vessel during expansion of the prosthetic.
摘要翻译：血管内袖带充当天然血管和血管内修复装置之间的衬里。在展开期间，袖带的端部自身卷曲并能够在端部之间捕获诸如瓣叶组织之类的天然组织。袖带在容器和假体之间形成密封，从而防止假肢周围的泄漏。袖口还捕获在假肢扩张期间从血管中移出的任何栓塞物质。

5. 发明申请

WO2008040014A2 DELIVERY TOOL FOR PERCUTANEOUS DELIVERY OF A PROSTHESIS 审中-公开
标题翻译：用于经皮递送假体的递送工具
公开(公告)号：WO2008040014A2
公开(公告)日：2008-04-03
申请号：PCT/US2007/079978
申请日：2007-09-28
申请人： HEART LEAFLET TECHNOLOGIES, INC. , ROBERT, Foster, Wilson , JOHN, Gainor
发明人： ROBERT, Foster, Wilson , JOHN, Gainor
IPC分类号： A61F2/24
CPC分类号： A61F2/243 , A61F2/2418 , A61F2/2436 , A61F2/95
摘要： An expandable delivery tool for aiding the deployment of a prosthesis device within a patient. The delivery tool has a generally elongated shape with a selectively expandable distal end region that flares outward in diameter. Once advanced percutaneously within a patient's vessel, the delivery device can help locate a target area, assist in deploying a prosthesis at a desired position and further expand the prosthesis after deployment.
摘要翻译：用于帮助在患者体内展开假体装置的可扩展的递送工具。输送工具具有大致细长的形状，其具有直径向外扩张的可选择性扩张的远端区域。一旦在患者血管内经皮前进，递送装置可以帮助定位目标区域，帮助在所需位置部署假体并且在部署后进一步扩张假体。

6. 发明申请

WO2013052171A3 MANIPULATION OF FLAMES AND RELATED METHODS AND APPARATUS 审中-公开
标题翻译：火焰的操作及相关方法和装置
公开(公告)号：WO2013052171A3
公开(公告)日：2013-06-20
申请号：PCT/US2012040171
申请日：2012-05-31
申请人： HARVARD COLLEGE , CADEMARTIRI LUDOVICO , MACE CHARLES R , SHEPHERD ROBERT FOSTER , MAZZEO AARON D , BISHOP KYLE J M , CHIECHI RYAN C , WHITESIDES GEORGE M
发明人： CADEMARTIRI LUDOVICO , MACE CHARLES R , SHEPHERD ROBERT FOSTER , MAZZEO AARON D , BISHOP KYLE J M , CHIECHI RYAN C , WHITESIDES GEORGE M
IPC分类号： F23D14/00 , F23D14/84 , F23D99/00 , F23N5/00
CPC分类号： F23N5/00 , F23C99/001
摘要： Manipulation of flames is described using electric fields. In those instances in which electric fields are used, the electric fields may be time-varying gradient electric fields, and in some instances may be oscillating electiic fields. The manipulation may include extinction, suppression, control of mixing of the flame, concentration, and/or bending, among other types.
摘要翻译：使用电场描述火焰的操纵。在使用电场的情况下，电场可以是时变梯度电场，并且在一些情况下可以是振荡电场。操作可以包括灭火，抑制，火焰混合的控制，浓缩和/或弯曲等。

7. 发明申请

WO2013052171A2 MANIPULATION OF FLAMES AND RELATED METHODS AND APPARATUS 审中-公开
标题翻译：火焰的操纵及相关方法和设备
公开(公告)号：WO2013052171A2
公开(公告)日：2013-04-11
申请号：PCT/US2012/040171
申请日：2012-05-31
申请人： PRESIDENT AND FELLOWS OF HARVARD COLLEGE , CADEMARTIRI, Ludovico , MACE, Charles, R. , SHEPHERD, Robert, Foster , MAZZEO, Aaron, D. , BISHOP, Kyle, J.m. , CHIECHI, Ryan, C. , WHITESIDES, George, M.
发明人： CADEMARTIRI, Ludovico , MACE, Charles, R. , SHEPHERD, Robert, Foster , MAZZEO, Aaron, D. , BISHOP, Kyle, J.m. , CHIECHI, Ryan, C. , WHITESIDES, George, M.
IPC分类号： F23D14/00 , F23N5/00 , F23D14/84 , F23D99/00
CPC分类号： F23N5/00 , F23C99/001
摘要： Manipulation of flames is described using electric fields. In those instances in which electric fields are used, the electric fields may be time-varying gradient electric fields, and in some instances may be oscillating electiic fields. The manipulation may include extinction, suppression, control of mixing of the flame, concentration, and/or bending, among other types.
摘要翻译：使用电场来描述火焰的操作。在使用电场的那些情况下，电场可以是时变的梯度电场，并且在一些情况下可以是振荡电场。操纵可以包括熄灭，抑制，火焰混合的控制，浓度和/或弯曲等等。

8. 发明申请

WO2004019811A8 METHOD AND DEVICE FOR TREATING DISEASED VALVE 审中-公开
标题翻译：用于治疗疾病的阀门的方法和装置
公开(公告)号：WO2004019811A8
公开(公告)日：2010-11-04
申请号：PCT/US0326924
申请日：2003-08-28
申请人： HEART LEAFLET TECHNOLOGIES , WILSON ROBERT FOSTER , SCOTT ROBERT WILSON , POKORNEY JAMES L
发明人： WILSON ROBERT FOSTER , SCOTT ROBERT WILSON , POKORNEY JAMES L
IPC分类号： A61B17/32 , A61F20060101 , A61F2/24
CPC分类号： A61F2/2418 , A61F2/2427 , A61F2/2463 , A61F2/2466 , Y10S623/904
摘要： A native tricuspid valve (5) with a valve implant (10) of the present invention being installed in each leaflet (7). The valve implants (10) allow blood to flow therethrough, in one direction, even though the native tricuspid valve (5) remains closed. The valve implants (10) would similarly work in a native bicuspid valve, unicuspid valve or quadricuspid valve alleviating problems associated with calcified tissue (9) of a stenosed native valve (5).
摘要翻译：具有本发明的瓣膜植入物（10）的本地三尖瓣（5）安装在每个小叶（7）中。即使天然三尖瓣（5）保持关闭，瓣膜植入物（10）允许血液在一个方向上流过其中。瓣膜植入物（10）将类似地用于天然二尖瓣，单瓣瓣或四瓣瓣，以减轻与狭窄的天然瓣膜（5）的钙化组织（9）相关的问题。

9. 发明申请

WO2008037022A1 A BLOCK AND A SYSTEM FOR USE IN BUILDING A STRUCTURE 审中-公开
标题翻译：一种用于建筑结构的块和系统
公开(公告)号：WO2008037022A1
公开(公告)日：2008-04-03
申请号：PCT/AU2007/001444
申请日：2007-09-28
申请人： BUILDING INNOVATIONS PTY LTD , COLEFAX, Warwick, Ian , COLEFAX, Robert, Foster
发明人： COLEFAX, Warwick, Ian , COLEFAX, Robert, Foster
IPC分类号： E04B1/04 , E04C1/00 , E04B1/41 , F16B1/00
CPC分类号： E04B2/8629 , E04B2/42 , E04B2/54 , E04B2002/025 , E04B2002/867 , E04B2002/8676
摘要： A block for use in building a structure, the block comprising a body and at least one cavity extending through the body, the body having two side walls and at least one open end, the block also comprising at least one laterally extending wall extending between the two side walls and defining one end of the cavity, the at least one laterally extending wall having an aperture formed therein for enabling the passage of grout or any other core filling material from the at least one cavity to the at least one open end of the body when building the structure, wherein, inner corners of end edges of the side walls at the at least one open end of the block are chamfered, the chamfered end edges for forming a void between each of the side walls and the side walls of another block laid end to end with the block to enable grout or any other core filling material to be provided close to the outer faces of the block.
摘要翻译：一种用于构造结构的块，所述块包括主体和延伸穿过所述主体的至少一个空腔，所述主体具有两个侧壁和至少一个开放端，所述块还包括至少一个横向延伸的壁，两个侧壁并且限定空腔的一端，所述至少一个横向延伸的壁具有形成在其中的孔，用于使得浆料或任何其它芯填充材料能够从所述至少一个空腔通向所述至少一个开口端在构造所述结构体的情况下，在所述块的至少一个开口端处的侧壁的端部边缘的内角被倒角，所述倒角端边缘用于在每个侧壁和另一侧壁的侧壁之间形成空隙块体以块体方式放置成端部，以使灌浆或任何其它芯填充材料靠近块体的外表面提供。

10. 发明申请

WO2006128193A3 STENTLESS SUPPORT STRUCTURE 审中-公开
公开(公告)号：WO2006128193A3
公开(公告)日：2006-11-30
申请号：PCT/US2006/021021
申请日：2006-05-30
申请人： HEART LEAFLET TECHNOLOGIES, INC. , THILL, Gary, A. , WILSON, Robert, Foster , GAINOR, John , BANICK, Christopher, M.
发明人： THILL, Gary, A. , WILSON, Robert, Foster , GAINOR, John , BANICK, Christopher, M.
IPC分类号： A61F2/06 , A61F2/24
摘要： A stentless support structure capable of being at least partly assembled in situ. The support structure comprises a braided tube that is very flexible and, when elongated, becomes very long and very small in diameter, thereby being capable of placement within a small diameter catheter. The support structure is preferably constructed of one or more thin strands of a super-elastic or shape memory material such as Nitinol. When released from the catheter, the support structure folds itself into a longitudinally compact configuration. The support structure thus gains significant strength as the number of folds increase. This radial strength obviates the need for a support stent. The support structure may include attachment points for a prosthetic valve.

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