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    • 2. 发明申请
    • METHOD AND DEVICE FOR THREE-STAGE ATRIAL CARDIOVERSION THERAPY
    • 用于三期ATRIAL CARDIOVERSION治疗的方法和装置
    • WO2011139596A3
    • 2012-03-08
    • PCT/US2011033547
    • 2011-04-22
    • UNIV WASHINGTONEFIMOV IGOR RFEDOROV VADIM VRIPPLINGER CRYSTAL MFOYIL KELLEY VAMBROSI CHRISTINA M
    • EFIMOV IGOR RFEDOROV VADIM VRIPPLINGER CRYSTAL MFOYIL KELLEY VAMBROSI CHRISTINA M
    • A61N1/38A61N1/05A61N1/36A61N1/372
    • A61N1/3956A61N1/3624A61N1/3906A61N1/395A61N1/3987
    • Methods and apparatus for a three-stage atrial cardioversion therapy that treats atrial arrhythmias within pain tolerance thresholds of a patient. An implantable therapy generator adapted to generate and selectively deliver a three-stage atrial cardioversion therapy and at least two leads operably each having at least one electrode adapted to be positioned proximate the atrium of the patient. The device is programmed with a set of therapy parameters for delivering a three-stage atrial cardioversion therapy to the patient via both a far-field configuration and a near-field configuration of the electrodes upon detection of an atrial arrhythmia. The three-stage atrial cardioversion therapy includes a first stage for unpinning of one or more singularities associated with an atrial arrhythmia, a second stage for anti-repinning of the one or more singularities associated with the atrial arrhythmia, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of the one or more singularities associated with the atrial arrhythmia delivered via the near-field configuration of the electrodes.
    • 用于治疗患者疼痛耐受阈值内心房心律失常的三期心房心脏复律治疗方法和装置。 一种植入式治疗发生器,其适于产生和选择性地递送三阶段心房复律治疗和至少两个可操作的引线,每个引线具有至少一个适于定位在患者的心房附近的电极。 该装置被编程有一组治疗参数,用于在检测到房性心律失常时通过远场配置和电极的近场配置向患者传送三级心房复律治疗。 三级心房复律治疗包括用于解除与心房心律失常相关的一个或多个奇异点的第一阶段,用于抗心律失常相关的一个或多个奇点的第二阶段,其中两个都通过 电极的远场结构,以及用于熄灭与通过电极的近场结构输送的心房心律失常相关联的一个或多个奇异点的第三阶段。
    • 3. 发明申请
    • METHOD AND DEVICE FOR THREE-STAGE ATRIAL CARDIOVERSION THERAPY
    • 用于三期ATRIAL CARDIOVERSION治疗的方法和装置
    • WO2011139596A2
    • 2011-11-10
    • PCT/US2011/033547
    • 2011-04-22
    • THE WASHINGTON UNIVERSITYEFIMOV, Igor, R.FEDOROV, Vadim, V.RIPPLINGER, Crystal, M.FOYIL, Kelley, V.AMBROSI, Christina, M.
    • EFIMOV, Igor, R.FEDOROV, Vadim, V.RIPPLINGER, Crystal, M.FOYIL, Kelley, V.AMBROSI, Christina, M.
    • A61N1/38A61N1/05A61N1/372A61N1/36
    • A61N1/3956A61N1/3624A61N1/3906A61N1/395A61N1/3987
    • Methods and apparatus for a three-stage atrial cardioversion therapy that treats atrial arrhythmias within pain tolerance thresholds of a patient. An implantable therapy generator adapted to generate and selectively deliver a three-stage atrial cardioversion therapy and at least two leads operably each having at least one electrode adapted to be positioned proximate the atrium of the patient. The device is programmed with a set of therapy parameters for delivering a three-stage atrial cardioversion therapy to the patient via both a far-field configuration and a near-field configuration of the electrodes upon detection of an atrial arrhythmia. The three-stage atrial cardioversion therapy includes a first stage for unpinning of one or more singularities associated with an atrial arrhythmia, a second stage for anti-repinning of the one or more singularities associated with the atrial arrhythmia, both of which are delivered via the far-field configuration of the electrodes, and a third stage for extinguishing of the one or more singularities associated with the atrial arrhythmia delivered via the near-field configuration of the electrodes.
    • 用于治疗患者疼痛耐受阈值内心房心律失常的三期心房心脏复律治疗方法和装置。 一种植入式治疗发生器,其适于产生和选择性地递送三阶段心房复律治疗和至少两个可操作的引线,每个引线具有至少一个适于定位在患者的心房附近的电极。 该装置被编程有一组治疗参数,用于在检测到房性心律失常时通过远场配置和电极的近场配置向患者传送三级心房复律治疗。 三级心房复律治疗包括用于解除与心房心律失常相关的一个或多个奇异点的第一阶段,用于抗心律失常相关的一个或多个奇点的第二阶段,其中两个都通过 电极的远场结构,以及用于熄灭与通过电极的近场结构输送的心房心律失常相关联的一个或多个奇异点的第三阶段。