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1. 发明申请

US20110213299A1 MEDICAL INJECTOR WITH BUTTON ACTIVATION 有权
标题翻译：具有按钮激活的医用注射器
公开(公告)号：US20110213299A1
公开(公告)日：2011-09-01
申请号：US13063849
申请日：2009-09-18
申请人： Richard A. Cronenberg
发明人： Richard A. Cronenberg
IPC分类号： A61M5/315 , A61M5/31
CPC分类号： A61M5/2033 , A61M5/2066 , A61M5/3146 , A61M5/31553 , A61M5/3156 , A61M2005/2451
摘要： A medical injector is provided herein which includes a body; a slidable button at least partially disposed in the body; a displaceable plunger disposed in the body; a spring disposed to advance the plunger; and, a releasable retainer for retaining the plunger in a first state against force of the spring. Upon a predetermined extent of sliding movement of the button, the button engages the releasable retainer so as to cause the releasable retainer to release the plunger thus allowing the spring to advance the plunger. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon button activation, thereby minimizing premature or failed activations.
摘要翻译：本文提供了一种医用注射器，其包括主体; 至少部分地布置在所述主体中的可滑动按钮; 设置在本体中的可移位柱塞; 设置成使柱塞前进的弹簧; 以及用于将柱塞保持在第一状态以抵抗弹簧的力的可释放保持器。在按钮的预定程度的滑动运动中，按钮与可释放的保持器接合，以便使可释放的保持器释放柱塞，从而允许弹簧推进柱塞。有利地，本发明提供一种具有自动柱塞驱动器的医用注射器，其在按钮激活时被触发，从而最小化过早或失败的激活。

2. 发明申请

US20110202013A1 MEDICAL INJECTOR WITH COUPLED BODY PORTIONS 有权
标题翻译：医用注射器与联接体部分
公开(公告)号：US20110202013A1
公开(公告)日：2011-08-18
申请号：US13063806
申请日：2009-09-18
申请人： Ruane S. Jeter , Richard A. Cronenberg , Lionel Verdrine , Atul Patel
发明人： Ruane S. Jeter , Richard A. Cronenberg , Lionel Verdrine , Atul Patel
IPC分类号： A61M5/315
CPC分类号： A61M5/3158 , A61M5/002 , A61M5/3205 , A61M5/3213 , A61M2005/2407 , A61M2005/2496
摘要： A medical injector is provided herein which includes first and second body portions each having a longitudinal axis and configured to couple at a coupling. The first and second body portions are complementarily formed so as to be movable about the coupling. The medical injector also includes an axially-displaceable plunger; biasing element for advancing the plunger a predetermined distance; and, a releasable retainer for releasably retaining the plunger in a first state against the force of the biasing element. In an initial state, the axes of the first and second body portions are not aligned and the plunger is in the first state. In a coupled state, the axes of the first and second body portions are axially aligned, and the releasable retainer releases the plunger, thereby allowing the biasing element to advance the plunger the predetermined distance. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon assembly of the pen injector, thereby minimizing premature or failed activations.
摘要翻译：本文提供了一种医疗注射器，其包括第一和第二主体部分，每个主体部分具有纵向轴线并且构造成在联接件处联接。第一主体部分和第二主体部分互补地形成为可围绕联接器移动。医疗注射器还包括可轴向移动的柱塞; 用于使柱塞前进预定距离的偏压元件; 以及可释放的保持器，用于将柱塞可释放地保持在抵抗偏置元件的力的第一状态。在初始状态下，第一和第二主体部分的轴线不对齐，并且柱塞处于第一状态。在联接状态下，第一主体部分和第二主体部分的轴线被轴向对齐，并且可释放保持器释放柱塞，从而允许偏置元件将柱塞推进预定距离。有利地，本发明提供一种具有自动柱塞驱动器的医用注射器，其在笔注射器的组装时触发，由此最小化过早或失败的激活。

3. 发明申请

US20110201999A1 NEEDLE MOUNTING FEATURE FOR ENSURING PROPER RECONSTITUTION SEQUENCE 有权
标题翻译：用于确保适当重新配置顺序的针脚安装功能
公开(公告)号：US20110201999A1
公开(公告)日：2011-08-18
申请号：US13119200
申请日：2009-09-18
申请人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Matthew D. Sweeney , Lionel Vedrine
发明人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Matthew D. Sweeney , Lionel Vedrine
IPC分类号： A61M5/31 , A61M5/34
CPC分类号： A61M5/2448 , A61M5/2066 , A61M5/3129 , A61M5/3134 , A61M5/3243 , A61M5/344 , A61M5/347 , A61M2005/2407 , A61M2005/2496 , A61M2005/3104
摘要： A medical injector is provided herein having a body and a needle mounting surface movable relative to the body, the needle mounting surface having features for mounting a needle thereto. In an initial state, the needle mounting surface is disposed within the body with no needle mounted thereto. With relative movement between the body and the needle mounting surface, the needle mounting surface is urged out of the body. Advantageously, a medical injector is provided which ensures proper sequence in preparation of the device, particularly with respect to the step of allowing mounting of a medical needle to the device subsequent to preparation of the medicament to be administered.
摘要翻译：本发明提供了一种具有可相对于身体移动的主体和针安装表面的医疗注射器，针安装表面具有用于将针安装到其上的特征。在初始状态下，针安装表面设置在主体内，没有针安装在其上。通过主体和针安装表面之间的相对移动，针安装表面被推出身体。有利地，提供了一种医疗注射器，其确保在制备装置时的适当顺序，特别是关于在制备要施用的药物之后允许将医用针安装到装置的步骤。

4. 发明授权

US06977062B2 Automatic pipette identification 失效
标题翻译：自动移液器识别
公开(公告)号：US06977062B2
公开(公告)日：2005-12-20
申请号：US10612252
申请日：2003-07-01
申请人： Richard A. Cronenberg
发明人： Richard A. Cronenberg
IPC分类号： G01N1/00 , B01L3/02 , G01N35/10
CPC分类号： G01N35/10 , B01L3/0279 , B01L2200/143 , B01L2300/021 , G01N2035/0493 , G01N2035/103 , Y10T436/2575
摘要： Mechanisms are provided for automatically removing tips from a pipette nozzle and/or for detecting the type of tip mounted to the nozzle. For detipping, mechanical energy is stored when the tip is mounted to the nozzle and is released when the tip is to be removed to facilitate removal thereof. A mechanism is preferably provided which limits the force with which the tip is mounted to the nozzle and an overforce mechanism may be provided to facilitate removal of a stuck tip. For detecting tip type, each tip type has a different base configuration which results in a different relative displacement between the nozzle and a surrounding component as a result of the tip contacting both during tip mounting, the difference in relative displacement being detected to identify tip type.
摘要翻译：提供用于从移液管喷嘴自动移除尖端和/或用于检测安装到喷嘴的尖端的类型的机构。为了进行检测，当尖端安装到喷嘴上时，存储机械能量，并且当尖端要被移除以释放时便释放机械能以便于其移除。优选地提供限制将尖端安装到喷嘴的力的机构，并且可以设置过强力机构以便于移除卡住的末端。为了检测尖端类型，每个尖端类型具有不同的基本构造，这导致喷嘴和周围部件之间的不同相对位移，这是由于尖端安装期间的尖端接触而导致的，相对位移的差异被检测以识别尖端类型。

5. 发明申请

US20130274706A1 MEDICAL INJECTOR WITH POST-AUTORECONSTITUTION DOSE SETTING AND AUTOPLUNGER DRIVE 审中-公开
标题翻译：医用注射器，具有自动跟踪剂量设定和自动启动器驱动
公开(公告)号：US20130274706A1
公开(公告)日：2013-10-17
申请号：US13916101
申请日：2013-06-12
申请人： RICHARD A. CRONENBERG , ASIF FAYYAZ , ATUL PATEL
发明人： RICHARD A. CRONENBERG , ASIF FAYYAZ , ATUL PATEL
IPC分类号： A61M5/19
CPC分类号： A61M5/19 , A61M5/2033 , A61M5/2066 , A61M5/2448 , A61M5/3129 , A61M5/31553 , A61M5/3156
摘要： A medical injector is provided herein having a body; a reservoir containing first and second mixable components; a stopper; a plunger disposed in the body; a spring disposed to advance the plunger; a first releasable retainer for releasably retaining the plunger in a first state against force of the spring; a first trigger for causing the first releasable retainer to release the plunger; a second releasable retainer for releasably retaining the plunger in a second state against force of the spring; and, a second trigger for causing the second releasable retainer to release the plunger. The spring causes the plunger to advance so that the stopper traverses at least a predetermined extent of advancement thereby causing mixing of the first and second mixable components. Advantageously, with the subject invention, a medical injector is provided which allows for autoreconstitution with subsequent dose setting and autoplunger activation being activated by separate triggers.
摘要翻译：本发明提供一种具有身体的医用注射器; 包含第一和第二可混合组分的储存器; 塞子设置在所述主体中的柱塞; 设置成使柱塞前进的弹簧; 第一可释放保持器，用于将柱塞可释放地保持在第一状态，抵抗弹簧的力; 用于使第一可释放保持器释放柱塞的第一触发器; 第二可释放保持器，用于将所述柱塞可释放地保持在抵抗所述弹簧的力的第二状态; 以及用于使第二可释放保持器释放柱塞的第二触发器。弹簧使柱塞前进，使得止动件至少延伸一定程度的前进，从而引起第一和第二可混合部件的混合。有利地，对于本发明，提供了一种医疗注射器，其允许自动重新配置，随后的剂量设定和自动活动激活由单独的触发器激活。

6. 发明申请

US20120041366A1 MEDICAL INJECTOR WITH DOSE KNOB ACTIVATION FOR AUTOMATED RECONSTITUTION 有权
标题翻译：医用注射器，用于自动重新配置的激素
公开(公告)号：US20120041366A1
公开(公告)日：2012-02-16
申请号：US13119014
申请日：2009-09-18
申请人： Asif Fayyaz , Richard A. Cronenberg , Lionel Vedrine
发明人： Asif Fayyaz , Richard A. Cronenberg , Lionel Vedrine
IPC分类号： A61M5/31
CPC分类号： A61M5/2066 , A61M5/2448 , A61M5/3146 , A61M5/31553 , A61M5/3156 , A61M5/3158 , A61M5/31591
摘要： A medical injector is provided herein having a body and a reservoir disposed in the body, the reservoir including at least first and second mixable components. At least one stopper is associated with the reservoir where distal advancement of the stopper over a predetermined distance causes mixing of the mixable components. A plunger is disposed in the body, along with a knob stem and a knob fixed to the knob stem so as to be rotatable therewith. A sleeve is telescopingly disposed over the knob stem, wherein the knob stem and the sleeve have cooperating elements formed thereon which selectively permit rotation of the knob stem to be transmitted to the sleeve so that the knob stem and the sleeve may rotate together. A spring is also provided for urging the sleeve distally. A releasable retainer releasably retains the sleeve against force of the spring. Rotation of the knob releases the sleeve and allows the spring to displace the sleeve distally. Distal movement of the sleeve causes distal movement of the plunger which causes distal movement of the stopper thus causing mixing of the mixable components. Advantageously, with the subject invention, a medical injector may be provided where autoreconstitution can be achieved by the turning of a knob.
摘要翻译：本发明提供一种医疗注射器，其具有主体和设置在主体中的储存器，储存器包括至少第一和第二可混合部件。至少一个止动件与储存器相关联，止动器的远端前进超过预定距离导致可混合部件的混合。柱塞被设置在主体中，以及旋钮杆和固定到旋钮杆的旋钮，以便与其一起旋转。套筒可伸缩地设置在旋钮杆上，其中旋钮杆和套筒具有形成在其上的协作元件，其选择性地允许旋钮杆旋转以传递到套筒，使得旋钮杆和套筒可以一起旋转。还提供用于向远端推动套筒的弹簧。可释放的保持器可释放地保持套筒抵抗弹簧的力。旋钮的旋转释放套筒并允许弹簧向远侧移动套筒。套筒的远端运动导致柱塞的远端运动，其导致塞子的远端运动，从而引起可混合部件的混合。有利地，通过本发明，可以提供医疗注射器，其中可以通过旋转旋钮来实现自动重构。

7. 发明授权

US4327718A Continuously draining trap for removal of condensate from a patient breathing circuit 失效
标题翻译：连续排出陷阱，以从患者呼吸回路中清除冷凝水
公开(公告)号：US4327718A
公开(公告)日：1982-05-04
申请号：US188393
申请日：1980-09-18
申请人： Richard A. Cronenberg
发明人： Richard A. Cronenberg
IPC分类号： A61M16/08 , A61M16/00
CPC分类号： A61M16/0808 , Y10S55/35
摘要： A drain device for the continuous removal of condensate from an operational patient breathing circuit comprises a body having a first opening adapted for connection to a patient breathing apparatus. A second opening in the body is adapted for connection to a patient breathing device. There is a passageway in the body which provides fluid communication between these openings, with a third opening through the body communicating with the passageway. A liquid-pervious, gas-impervious material covers the third opening so that condensate can continuously drain through the third opening while the breathing circuit is in operation.
摘要翻译：用于从操作的患者呼吸回路连续移除冷凝物的排水装置包括具有适于连接到患者呼吸装置的第一开口的主体。身体中的第二开口适于连接到患者呼吸装置。身体中有通道，其在这些开口之间提供流体连通，通过与通道连通的第三个开口。透液，不透气材料覆盖第三开口，使得在呼吸回路运行时，冷凝水可以连续排出第三开口。

8. 发明授权

US08936578B2 Medical injector with ratcheting plunger 有权
标题翻译：带棘轮柱塞的医用注射器
公开(公告)号：US08936578B2
公开(公告)日：2015-01-20
申请号：US13063814
申请日：2009-09-18
申请人： Richard A. Cronenberg
发明人： Richard A. Cronenberg
IPC分类号： A61M5/00 , A61M5/315 , A61M5/31
CPC分类号： A61M5/3158 , A61M5/31541 , A61M5/31555 , A61M5/31576 , A61M5/31581 , A61M5/31595 , A61M2005/3125 , A61M2005/3126 , A61M2205/583 , A61M2205/584
摘要： A medical injector is provided herein having a body with a displaceable plunger. The plunger includes a plurality of spaced-apart ratchet teeth disposed along the length thereof. At least one indexer is provided formed to engage the plunger, wherein the indexer is configured to allow the plunger to displace distally towards a distal end of the body but not proximally towards a proximal end of the body. The medical injector also includes an actuator having an engagement portion formed to engage one or more of the ratchet teeth. The actuator is displaceable to a ready state, the engagement portion being displaced proximally relative to the plunger with the actuator being displaced to the ready state. The indexer prevents proximal movement of the plunger thereby allowing the engagement portion to by-pass one or more of the ratchet teeth with the actuator being displaced to the ready state. In addition, the actuator is displaceable from the ready state to cause actuation of the medical injector. The displacement from the ready state causes distal displacement of the engagement portion with the engagement portion engaging one or more of the ratchet teeth and causing distal displacement of the plunger with the engagement portion. Advantageously, the subject invention provides a plunger for a medical injector which may be controllably advanced with a minimum number of cooperating parts.
摘要翻译：本发明提供一种医用注射器，其具有带有位移柱塞的主体。柱塞包括沿其长度设置的多个间隔开的棘轮齿。提供形成为接合柱塞的至少一个分度器，其中分度器构造成允许柱塞朝向身体的远端向远侧移动，而不向近侧朝向身体的近端移位。医疗注射器还包括具有形成为接合一个或多个棘齿的接合部的致动器。致动器可移动到就绪状态，接合部分相对于柱塞向近侧位移，致动器被移位到就绪状态。分度器防止柱塞的近端运动，从而允许接合部分绕过一个或多个棘轮齿，致动器被移动到就绪状态。此外，致动器可从就绪状态移位以引起医用注射器的致动。从就绪状态的位移导致接合部分的远端位移，其中接合部分接合一个或多个棘齿，并引起柱塞与接合部分的远端位移。有利地，本发明提供了一种用于医疗注射器的柱塞，其可以以最少数量的协作部件可控地前进。

9. 发明授权

US08323238B2 Medical injector with rotatable body portions 有权
标题翻译：具有旋转体部分的医用注射器
公开(公告)号：US08323238B2
公开(公告)日：2012-12-04
申请号：US13063829
申请日：2009-09-18
申请人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Lionel Vedrine
发明人： Richard A. Cronenberg , Asif Fayyaz , Atul Patel , Lionel Vedrine
IPC分类号： A61M37/00
CPC分类号： A61M5/2033 , A61M5/2448 , A61M5/3129 , A61M5/31553 , A61M5/3156 , A61M2005/2073
摘要： A medical injector is provided herein which includes first and second body portions rotatably coupled together; a displaceable plunger disposed in at least one of the first and second body portions; a spring disposed to advance the plunger; and, a releasable retainer for retaining the plunger in a first portion against force of the spring. The releasable retainer releases the plunger upon a predetermined extent of relative rotation between the first and second body portions, thus allowing the spring to advance the plunger. Advantageously, the subject invention provides a medical injector having an automated plunger drive which is triggered upon rotation of injector body portions, thereby minimizing premature or failed activations.
摘要翻译：本文提供了一种医疗注射器，其包括可旋转地联接在一起的第一和第二主体部分; 设置在所述第一和第二主体部分中的至少一个中的可移位柱塞; 设置成使柱塞前进的弹簧; 以及用于抵抗弹簧的力而将柱塞保持在第一部分中的可释放保持器。可释放的保持器在第一和第二主体部分之间的预定的相对旋转程度上释放柱塞，从而允许弹簧推进柱塞。有利地，本发明提供一种具有自动柱塞驱动器的医用注射器，其在喷射器主体部分的旋转时被触发，由此最小化过早或失败的激活。

10. 发明授权

US08114362B2 Automatic pipette identification 有权
标题翻译：自动移液器识别
公开(公告)号：US08114362B2
公开(公告)日：2012-02-14
申请号：US11243940
申请日：2005-10-04
申请人： Richard A. Cronenberg
发明人： Richard A. Cronenberg
IPC分类号： B01L3/02
CPC分类号： G01N35/10 , B01L3/0279 , B01L2200/143 , B01L2300/021 , G01N2035/0493 , G01N2035/103 , Y10T436/2575
摘要： Mechanisms are provided for automatically removing tips from a pipette nozzle and/or for detecting the type of tip mounted to the nozzle. For detipping, mechanical energy is stored when the tip is mounted to the nozzle and is released when the tip is to be removed to facilitate removal thereof. A mechanism is preferably provided which limits the force with which the tip is mounted to the nozzle and an overforce mechanism may be provided to facilitate removal of a stuck tip. For detecting tip type, each tip type has a different base configuration which results in a different relative displacement between the nozzle and a surrounding component as a result of the tip contacting both during tip mounting, the difference in relative displacement being detected to identify tip type.
摘要翻译：提供用于从移液管喷嘴自动移除尖端和/或用于检测安装到喷嘴的尖端的类型的机构。为了进行检测，当尖端安装到喷嘴上时，存储机械能量，并且当尖端要被移除以释放时便释放机械能以便于其移除。优选地提供限制将尖端安装到喷嘴的力的机构，并且可以设置过强力机构以便于移除卡住的末端。为了检测尖端类型，每个尖端类型具有不同的基本构造，这导致喷嘴和周围部件之间的不同相对位移，这是由于尖端安装期间的尖端接触而导致的，相对位移的差异被检测以识别尖端类型。

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