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1. 发明专利

AU5549700A Portable sensing devices 未知
公开(公告)号：AU5549700A
公开(公告)日：2001-01-09
申请号：AU5549700
申请日：2000-06-21
申请人： ALEXANDER WOODHATCH , CHRISTOS PAPAVASSILIOU , MARINA CORIOLANO LYKOUREZOS , YANG LI , QIANG LI , ZHIHONG YU
发明人： WOODHATCH ALEXANDER , PAPAVASSILIOU CHRISTOS , CORIOLANO-LYKOUREZOS MARINA , LI YANG , LI QIANG , YU ZHIHONG
IPC分类号： G09B5/06

2. 发明专利

GB9914465D0 Portable sensing devices 未知
公开(公告)号：GB9914465D0
公开(公告)日：1999-08-18
申请号：GB9914465
申请日：1999-06-21
申请人： CORIOLANO LYKOUREZOS MARINA A , WOODHATCH ALEXANDER W , QIANG LI , ZHIHONG YU
IPC分类号： G09B5/06

3. 发明申请

WO2007084595A2 BENZENESULFONYL-CHROMANE, THIOCHROMANE, TETRAHYDRONAPHTHALENE AND RELATED GAMMA SECRETASE INHIBITORS 审中-公开
标题翻译：苯并呋喃酮，噻吗啉，四氢萘酮和相关的游离氨基酸酶抑制剂
公开(公告)号：WO2007084595A2
公开(公告)日：2007-07-26
申请号：PCT/US2007/001302
申请日：2007-01-18
申请人： SCHERING CORPORATION , ASBEROM, Theodros , BARA, Thomas , BENNETT, Chad, E. , BURNETT, Duane, A. , CAPLEN, Mary Ann , CLADER, John, W. , COLE, David, J. , DOMALSKI, Martin, S. , JOSIEN, Hubert, B. , KNUTSON, Chad, E. , LI, Hongmei , MCBRIAR, Mark, D. , PISSARNITSKI, Dmitri, A. , QIANG, Li , RAJAGOPALAN, Murali , SASIKUMAR, Thavalakulamgar, K. , SU, Jing , TANG, Haiqun , WU, Wen-Lian , XU, Ruo , ZHAO, Zhiqiang
发明人： ASBEROM, Theodros , BARA, Thomas , BENNETT, Chad, E. , BURNETT, Duane, A. , CAPLEN, Mary Ann , CLADER, John, W. , COLE, David, J. , DOMALSKI, Martin, S. , JOSIEN, Hubert, B. , KNUTSON, Chad, E. , LI, Hongmei , MCBRIAR, Mark, D. , PISSARNITSKI, Dmitri, A. , QIANG, Li , RAJAGOPALAN, Murali , SASIKUMAR, Thavalakulamgar, K. , SU, Jing , TANG, Haiqun , WU, Wen-Lian , XU, Ruo , ZHAO, Zhiqiang
IPC分类号： C07D311/22 , C07D311/80 , C07D311/92 , C07D311/94 , C07D313/08 , C07D335/06
CPC分类号： C07D311/22 , C07C317/14 , C07C317/20 , C07C317/44 , C07C2602/08 , C07C2602/10 , C07C2602/12 , C07D311/80 , C07D311/92 , C07D311/94 , C07D313/08 , C07D335/06 , C07D405/12 , C07D409/12 , C07D491/04 , C07D493/04
摘要： This invention discloses novel gamma secretase inhibitors of the formula: R 2 and R 3 , or R 2 and R 4 , or R 3 and R 4 , together with the atoms to which they are bound, can form a fused cycloalkyl or fused heterocycloalkyl ring. The cycloalkyl ring or the heterocycloalkyl ring can be optionally substituted with one or more substituents. One or more compounds of formula (I), or formulations comprising such compounds, may be useful, e.g. in treating Alzheimer's Disease.
摘要翻译：本发明公开了下式的新型γ分泌酶抑制剂：R 2和R 3，或R 2和R 4 O / >或R 3和R 4与它们所连接的原子一起可以形成稠合的环烷基或稠合的杂环烷基环。环烷基环或杂环烷基环可任选被一个或多个取代基取代。一种或多种式（I）化合物或包含这些化合物的制剂可以是有用的，例如，治疗阿尔茨海默病。

4. 发明申请

WO2005035504A3 5-H -BENZO [D] NAPHTH [2, 1-B] AZEPINE DERIVATIVE AS SELECTIVE D1/D5 RECEPTOR ANTAGONISTS FOR THE TREATMENT OF OBESITY AND CNS DISORDERS 审中-公开
标题翻译： 5-H-BENZO [D] NAPHTH [2,1-B] AZEPINE衍生物作为选择性D1 / D5受体拮抗剂治疗肥胖和CNS疾病
公开(公告)号：WO2005035504A3
公开(公告)日：2005-06-30
申请号：PCT/US2004015760
申请日：2004-05-20
申请人： SCHERING CORP , BURNETT DUANE A , GREENLEE WILLIAM J , MCKITTRICK BRIAN , SU JING , ZHU ZHAONING , SASIKUMAR THAVALAKULAMGARA K , MAZZOLA ROBERT , QIANG LI , YE YUANZAN
发明人： BURNETT DUANE A , GREENLEE WILLIAM J , MCKITTRICK BRIAN , SU JING , ZHU ZHAONING , SASIKUMAR THAVALAKULAMGARA K , MAZZOLA ROBERT , QIANG LI , YE YUANZAN
IPC分类号： C07D223/14 , C07D401/12 , C07D403/10 , C07D407/12
CPC分类号： C07D223/14
摘要： The present invention provides compounds of formula (I), which, are novel antagonists for D1/D5 receptors as well as methods for preparing such compounds. In another embodiment, the invention provides pharmaceutical compositions comprising such D1/D5 receptor antagonists as well as methods of using them to treat CNS disorders, obesity, metabolic disorders, eating disorders such as hyperphagia, and diabetes.
摘要翻译：本发明提供式（I）化合物，其为D1 / D5受体的新型拮抗剂以及制备这些化合物的方法。在另一个实施方案中，本发明提供了包含这种D1 / D5受体拮抗剂的药物组合物以及使用它们治疗CNS障碍，肥胖，代谢紊乱，进食障碍如食欲过盛和糖尿病的方法。

5. 发明申请

WO2011053561A1 MICROEMULSION SPORICIDAL COMPOSITION 审中-公开
标题翻译：微乳液SPORICIDAL组合物
公开(公告)号：WO2011053561A1
公开(公告)日：2011-05-05
申请号：PCT/US2010/054016
申请日：2010-10-26
申请人： ETHICON, INC. , QIANG, Li
发明人： QIANG, Li
IPC分类号： A01N35/04 , A01P1/00
CPC分类号： A01N25/04 , A01N33/12 , A01N35/04 , A01N43/653 , A01N31/02 , A01N2300/00
摘要： A sporicidal composition comprising an aromatic dialdehyde; a medium chain linear alcohol; a surfactant; greater than 0.2% by weight based on the total weight of the composition of a base; and water, wherein the sporicidal composition is a microemulsion having a pH ranging from about 1 1 to about 13.
摘要翻译：一种包含芳族二醛的杀芽孢组合物; 中链线性醇; 表面活性剂; 基于组合物的总重量大于0.2重量％和水，其中杀芽孢组合物是pH为约11至约13的微乳。

6. 发明申请

WO2008119070A1 METHODS OF TREATMENT USING SIRT MODULATORS AND COMPOSITIONS CONTAINING SIRT1 MODULATORS 审中-公开
标题翻译：使用SIRT调节剂的治疗方法和含SIRT1调节剂的组合物
公开(公告)号：WO2008119070A1
公开(公告)日：2008-10-02
申请号：PCT/US2008/058738
申请日：2008-03-28
申请人： TRUSTEES OF BOSTON UNIVERSITY , FARMER, Stephen, R. , WANG, Hong , QIANG, Li
发明人： FARMER, Stephen, R. , WANG, Hong , QIANG, Li
IPC分类号： A61K31/40
CPC分类号： A61K45/06 , A61K31/40 , A61K31/4439 , A61K2300/00
摘要： Methods of treatment using SIR1 modulators and compositions containing SIRT1 modulators are described. Combinations of a SIRT1 modulator and a second agent, and uses of such combinations, are also described.
摘要翻译：描述了使用SIR1调节剂和含有SIRT1调节剂的组合物的治疗方法。还描述了SIRT1调节剂和第二种药剂的组合，以及这些组合的用途。

7. 发明申请

WO2007070393A2 MGLUR1 ANATGONISTS AS THERAPEUTIC AGENTS 审中-公开
标题翻译： MGLUR1 ANATGONISTS作为治疗剂
公开(公告)号：WO2007070393A2
公开(公告)日：2007-06-21
申请号：PCT/US2006046943
申请日：2006-12-11
申请人： SCHERING CORP , MATASI JULIUS J , TULSHIAN DEEN , BURNETT DUANE A , WU WEN-LIAN , KORAKAS PETER , SILVERMAN LISA S , THAVALAKULAMGARA SASIKUMAR K , QIANG LI , DOMALSKI MARTIN S
发明人： MATASI JULIUS J , TULSHIAN DEEN , BURNETT DUANE A , WU WEN-LIAN , KORAKAS PETER , SILVERMAN LISA S , THAVALAKULAMGARA SASIKUMAR K , QIANG LI , DOMALSKI MARTIN S
CPC分类号： C07D495/14
摘要： In its many embodiments, the present invention provides tricyclic compounds of formula (I) (wherein J 1 - J 4 , X, and R 1 - R 5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease.
摘要翻译：在其许多实施方案中，本发明提供了式（I）的三环化合物（其中J 1，X 4，X和R 1，（mGluR）拮抗剂（特别是作为选择性代谢型谷氨酸受体1拮抗剂），含有该化合物的药物组合物以及使用该化合物和组合物治疗治疗与代谢型谷氨酸受体（例如mGluR1）相关的疾病，例如疼痛，偏头痛，焦虑症，尿失禁和神经退行性疾病，例如阿尔茨海默氏病。

8. 发明申请

WO2006002051A1 TRICYCLIC COMPOUNDS AND THEIR USE AS MGLUR1 ANTAGONISTS 审中-公开
标题翻译：三氯化合物及其作为MGLUR1拮抗剂的用途
公开(公告)号：WO2006002051A1
公开(公告)日：2006-01-05
申请号：PCT/US2005/020972
申请日：2005-06-14
申请人： SCHERING CORPORATION , MATASI, Julius, J. , TULSHIAN, Deen , BURNETT, Duane, A. , WU, Wen-Lian , KORAKAS, Peter , SILVERMAN, Lisa, S. , SASIKUMAR, Thavalakulamgara, K. , QIANG, Li , DOMALSKI, Martin, S.
发明人： MATASI, Julius, J. , TULSHIAN, Deen , BURNETT, Duane, A. , WU, Wen-Lian , KORAKAS, Peter , SILVERMAN, Lisa, S. , SASIKUMAR, Thavalakulamgara, K. , QIANG, Li , DOMALSKI, Martin, S.
IPC分类号： C07D495/14
CPC分类号： C07D471/14 , C07D491/14 , C07D495/04 , C07D495/14 , C09B57/00
摘要： In its many embodiments, the present invention provides tricyclic compounds of Formula (I) (wherein J 1 -J 4 , X, and R 1 -R 5 are as defined herein) useful as metabotropic glutamate receptor (mGluR) antagonists, particularly as selective metabotropic glutamate receptor 1 antagonists, pharmaceutical compositions containing the compounds, and methods of treatment using the compounds and compositions to treat diseases associated with metabotropic glutamate receptor (e.g., mGluR1) such as, for example, pain, migraine, anxiety, urinary incontinence and neurodegenerative diseases such Alzheimer's disease.
摘要翻译：在其许多实施方案中，本发明提供式（I）的三环化合物（其中J

9. 发明申请

WO1994003718A1 AIR/FUEL MIXER FOR INTERNAL COMBUSTION ENGINES 审中-公开
标题翻译：用于内燃机的空气/燃油混合器
公开(公告)号：WO1994003718A1
公开(公告)日：1994-02-17
申请号：PCT/AU1993000405
申请日：1993-08-06
申请人： KING FORMAT LIMITED , MEMMOTT, Raymond, Robert , TAO, Ho, Yi , QIANG, Li, Hui , WU, Wu, Xiao
发明人： KING FORMAT LIMITED
IPC分类号： F02M21/04
CPC分类号： F02M21/0239 , F02B43/00 , F02M21/0212 , F02M21/0215 , F02M21/042 , F02M35/02483 , F02M35/042 , Y02T10/32
摘要： A fuel air mixer apparatus having a housing (10) replacing a conventional air cleaner assembly. An air filter element (14) divides the housing (10) into an air receiving chamber (15) and an air regulating and mixing chamber (16). The housing (10) is secured to the carburettor by means of a centre bolt (22). A regulator assembly (23) including a metal restrictor plate (24) is mounted concentrically on a guide portion (25) of the centre bolt (22). The metal restrictor plate (24) has an annular restrictor portion (26) adapted to be moved relative to a corresponding base restrictor portion (27) integrally formed in a base portion (11) of the housing (10). The base restrictor portion (27) forms the upper and outer surface of a gas distribution manifold (30) adapted to receive and feed gas to the engine. The metal restrictor plate (24) maintains a precisely controllable profile through the space defined between the annular restrictor portion (26) and the base restrictor portion (27) for changing between petrol and gas operation, with stability over time provided by eliminating the problems of aging and deformity of conventional rubber diaphragms.
摘要翻译：一种燃料空气混合装置，其具有替代常规空气滤清器组件的壳体（10）。空气过滤器元件（14）将壳体（10）分成空气接收室（15）和空气调节和混合室（16）。壳体（10）通过中心螺栓（22）固定在化油器上。包括金属限制板（24）的调节器组件（23）同心地安装在中心螺栓（22）的引导部分（25）上。金属限制板（24）具有环形限制器部分（26），其适于相对于整体形成在壳体（10）的基部（11）中的相应的基座限制器部分（27）移动。基座限制器部分（27）形成气体分配歧管（30）的上表面和外表面，该气体分配歧管适合于接收和供给发动机的气体。金属限制板（24）通过限定在环形限制器部分（26）和基座限制器部分（27）之间的空间保持精确可控的轮廓，用于在汽油和气体操作之间改变，随着时间的推移具有稳定性，通过消除以下问题：常规橡胶隔膜的老化和变形。

10. 发明申请

WO2007084595A3 CARBOCYCLIC AND HETEROCYCLIC ARYLSULFONES AS GAMMA SECRETASE INHIBITORS 审中-公开
标题翻译：作为GAMMA分泌酶抑制剂的CARBOCYCLICYCLIC AND HETEROCYCLIC ARYLSULFONES
公开(公告)号：WO2007084595A3
公开(公告)日：2007-09-07
申请号：PCT/US2007001302
申请日：2007-01-18
申请人： SCHERING CORP , ASBEROM THEODROS , BARA THOMAS , BENNETT CHAD E , BURNETT DUANE A , CAPLEN MARY ANN , CLADER JOHN W , COLE DAVID J , DOMALSKI MARTIN S , JOSIEN HUBERT B , KNUTSON CHAD E , LI HONGMEI , MCBRIAR MARK D , PISSARNITSKI DMITRI A , QIANG LI , RAJAGOPALAN MURALI , SASIKUMAR THAVALAKULAMGAR K , SU JING , TANG HAIQUN , WU WEN-LIAN , XU RUO , ZHAO ZHIQIANG
发明人： ASBEROM THEODROS , BARA THOMAS , BENNETT CHAD E , BURNETT DUANE A , CAPLEN MARY ANN , CLADER JOHN W , COLE DAVID J , DOMALSKI MARTIN S , JOSIEN HUBERT B , KNUTSON CHAD E , LI HONGMEI , MCBRIAR MARK D , PISSARNITSKI DMITRI A , QIANG LI , RAJAGOPALAN MURALI , SASIKUMAR THAVALAKULAMGAR K , SU JING , TANG HAIQUN , WU WEN-LIAN , XU RUO , ZHAO ZHIQIANG
IPC分类号： C07D311/22 , C07D311/80 , C07D311/92 , C07D311/94 , C07D313/08 , C07D335/06
CPC分类号： C07D311/22 , C07C317/14 , C07C317/20 , C07C317/44 , C07C2602/08 , C07C2602/10 , C07C2602/12 , C07D311/80 , C07D311/92 , C07D311/94 , C07D313/08 , C07D335/06 , C07D405/12 , C07D409/12 , C07D491/04 , C07D493/04
摘要： This invention discloses novel gamma secretase inhibitors of the formula: R 2 and R 3 , or R 2 and R 4 , or R 3 and R 4 , together with the atoms to which they are bound, can form a fused cycloalkyl or fused heterocycloalkyl ring. The cycloalkyl ring or the heterocycloalkyl ring can be optionally substituted with one or more substituents. One or more compounds of formula (I), or formulations comprising such compounds, may be useful, e.g. in treating Alzheimer's Disease.
摘要翻译：本发明公开了下式的新型γ分泌酶抑制剂：R 2和R 3，或R 2和R 4 O / >或R 3和R 4以及它们所结合的原子可以形成稠合的环烷基或稠合的杂环烷基环。环烷基环或杂环烷基环可任选被一个或多个取代基取代。一种或多种式（I）化合物或包含这些化合物的制剂可以是有用的，例如，治疗阿尔茨海默病。

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