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1. 发明申请

US20230099663A1 TASK-ORIENTED DEEP LEARNING IMAGE DENOISING 有权
公开(公告)号：US20230099663A1
公开(公告)日：2023-03-30
申请号：US17954561
申请日：2022-09-28
申请人： Pingkun Yan , Jiajin Zhang , Hanqing Chao , Ge Wang
发明人： Pingkun Yan , Jiajin Zhang , Hanqing Chao , Ge Wang
IPC分类号： G06T5/00
摘要： In one embodiment, there is provided an apparatus for denoising a medical image. The apparatus includes a denoising artificial neural network (ANN) configured to denoise input image data. The denoising ANN is trained, based at least in part, on at least one loss function. The at least one loss function includes a task-oriented loss.

2. 发明申请

US20090304265A1 SYSTEMS AND METHODS FOR MODELING THREE-DIMENSIONAL OBJECTS FROM TWO- DIMENSIONAL IMAGES 有权
标题翻译：用于从二维图像建模三维物体的系统和方法
公开(公告)号：US20090304265A1
公开(公告)日：2009-12-10
申请号：US12366241
申请日：2009-02-05
申请人： Saad M. Khan , Pingkun Yan , Mubarak Shah
发明人： Saad M. Khan , Pingkun Yan , Mubarak Shah
IPC分类号： G06T17/00 , G06K9/00
CPC分类号： G06T7/564 , G06T7/596 , G06T15/205 , G06T17/00
摘要： In one embodiment, a system and method for modeling a three-dimensional object includes capturing two-dimensional images of the object from multiple different viewpoints to obtain multiple views of the object, estimating slices of the object that lie in parallel planes that cut through the object, and computing a surface of the object from the estimated slices.
摘要翻译：在一个实施例中，用于对三维对象建模的系统和方法包括从多个不同视点捕获对象的二维图像以获得对象的多个视图，估计位于平行平面中的对象的切片对象，并从估计的切片计算对象的表面。

3. 发明授权

US11887298B2 Fluorescence lifetime imaging using deep learning 有权
公开(公告)号：US11887298B2
公开(公告)日：2024-01-30
申请号：US17143448
申请日：2021-01-07
申请人： Jason Tyler Smith , Ruoyang Yao , Xavier Intes , Pingkun Yan , Marien Ochoa-Mendoza
发明人： Jason Tyler Smith , Ruoyang Yao , Xavier Intes , Pingkun Yan , Marien Ochoa-Mendoza
IPC分类号： G06T7/00 , G06N3/088 , G06N3/045
CPC分类号： G06T7/0012 , G06N3/045 , G06N3/088 , G06T2207/10064 , G06T2207/20081 , G06T2207/20084 , G06T2207/30004
摘要： One embodiment provides an apparatus for fluorescence lifetime imaging (FLI). The apparatus includes a deep neural network (DNN). The DNN includes a first convolutional layer, a plurality of intermediate layers and an output layer. The first convolutional layer is configured to receive FLI input data. Each intermediate layer is configured to receive a respective intermediate input corresponding to an output of a respective prior layer. Each intermediate layer is further configured to provide a respective intermediate output related to the received respective intermediate input. The output layer is configured to provide estimated FLI output data corresponding to the received FLI input data. The DNN is trained using synthetic data.

4. 发明申请

US20230065196A1 PATIENT-SPECIFIC ORGAN DOSE QUANTIFICATION AND INVERSE OPTIMIZATION FOR CT 有权
公开(公告)号：US20230065196A1
公开(公告)日：2023-03-02
申请号：US17796715
申请日：2021-02-01
申请人： Xie George Xu , Pingkun Yan , Birsen Yazici
发明人： Xie George Xu , Pingkun Yan , Birsen Yazici
IPC分类号： G06T7/10 , A61B6/03 , A61B6/00 , G06T1/20
摘要： In one embodiment, there is provided a method of optimizing image quality and organ dose for computed tomography (CT). The method includes segmenting, by an organ segmentation module, at least one organ based, at least in part, on patient image data. The method further includes determining, by a Monte Carlo dose module, a patient-specific heterogeneous dose based, at least in part, on the patient image data and based, at least in part, on a selected CT scanner data. The method further includes determining, by a patient-specific organ dose module, a patient-specific nominal organ dose for each segmented organ based, at least in part, on the patient-specific heterogeneous dose. The method further includes determining, by an inverse optimization module, at least one CT scanner parameter configured to optimize image quality and a selected patient-specific organ dose of at least one selected organ.

5. 发明授权

US11051902B2 System and method for planning and performing a repeat interventional procedure 有权
公开(公告)号：US11051902B2
公开(公告)日：2021-07-06
申请号：US15754602
申请日：2016-08-10
申请人： Jochen Kruecker , Pingkun Yan , Amir Mohammad Tahmasebi Maraghoosh , Peter A Pinto , Bradford Johns Wood
发明人： Jochen Kruecker , Pingkun Yan , Amir Mohammad Tahmasebi Maraghoosh , Peter A Pinto , Bradford Johns Wood
IPC分类号： A61B5/05 , A61B90/00 , A61B34/10 , G16H10/40 , G16H30/20 , G16H50/30 , G16H50/20 , G16H30/40 , A61B8/08 , A61B8/00 , G06T7/00 , G06T11/00 , G16H20/40 , G16H40/63 , G16H70/20 , A61B10/02
摘要： A system for planning and performing a repeat interventional procedure includes a registration device (116) and an image generation device (120) which map current targets in a reference image (104) for a first interventional procedure to at least one guidance image (112) acquired from a different imaging modality. Biopsy locations are recorded to the guidance images during the first interventional procedure and the biopsy locations are mapped to the reference image to provide a planning image for use in a subsequent interventional procedure on the patient. In a subsequent interventional procedure, the prior planning image (124) may be registered to a current reference image (126) and the prior biopsy locations and prior and current targets are mapped to a guidance image acquired from a different imaging modality. Biopsy locations are then mapped to the guidance image (115) and mapped back to the current reference image.

6. 发明授权

US09993304B2 Visualization of catheter of three-dimensional ultrasound 有权
公开(公告)号：US09993304B2
公开(公告)日：2018-06-12
申请号：US13997800
申请日：2012-01-10
申请人： Pingkun Yan , Vijay Parthasarathy , Robert Manzke , Ameet Kumar Jain
发明人： Pingkun Yan , Vijay Parthasarathy , Robert Manzke , Ameet Kumar Jain
IPC分类号： A61B34/20 , A61B6/12 , A61B8/08 , A61B8/00
CPC分类号： A61B34/20 , A61B6/12 , A61B8/0883 , A61B8/466 , A61B8/483
摘要： An image-guided system includes an X-ray imaging device for generating one or more X-ray images illustrating a tool within an anatomical region, and an ultrasound imaging device for generating an ultrasound image illustrating the tool within the anatomical region. The image-guided system further includes a tool tracking device for visually tracking the tool within the anatomical region. In operation, the tool tracking device localizes a portion of the tool as located within the ultrasound image responsive to an identification of the portion of the tool as located within the X-ray image(s), and executes an image segmentation of an entirety of the tool as located within the ultrasound image relative to a localization of the portion of the tool as located within the ultrasound image.

7. 发明申请

US20210209759A1 FLUORESCENCE LIFETIME IMAGING USING DEEP LEARNING 有权
公开(公告)号：US20210209759A1
公开(公告)日：2021-07-08
申请号：US17143448
申请日：2021-01-07
申请人： Jason Tyler Smith , Ruoyang Yao , Xavier Intes , Pingkun Yan , Marien Ochoa-Mendoza
发明人： Jason Tyler Smith , Ruoyang Yao , Xavier Intes , Pingkun Yan , Marien Ochoa-Mendoza
IPC分类号： G06T7/00 , G06N3/04 , G06N3/08
摘要： One embodiment provides an apparatus for fluorescence lifetime imaging (FLI). The apparatus includes a deep neural network (DNN). The DNN includes a first convolutional layer, a plurality of intermediate layers and an output layer. The first convolutional layer is configured to receive FLI input data. Each intermediate layer is configured to receive a respective intermediate input corresponding to an output of a respective prior layer. Each intermediate layer is further configured to provide a respective intermediate output related to the received respective intermediate input. The output layer is configured to provide estimated FLI output data corresponding to the received FLI input data. The DNN is trained using synthetic data.

8. 发明申请

US20130289393A1 SYSTEM AND METHOD FOR NEEDLE DEPLOYMENT DETECTION IN IMAGE-GUIDED BIOPSY 有权
标题翻译：图像指导生物中针状部署检测的系统和方法
公开(公告)号：US20130289393A1
公开(公告)日：2013-10-31
申请号：US13978552
申请日：2012-01-12
申请人： Jochen Kruecker , Pingkun Yan , Alper Ayvaci
发明人： Jochen Kruecker , Pingkun Yan , Alper Ayvaci
IPC分类号： A61B8/08
CPC分类号： A61B8/0841 , A61B8/4245 , A61B8/4254 , A61B10/0241 , A61B10/0275 , A61B34/20 , A61B2034/2051 , A61B2090/365 , A61B2090/378
摘要： A system and method for medical device detection includes a guidance system (38) configured to deliver a surgical device (32) into a subject. A surgical device deployment detector (25, 40, 42, 44) is configured to cooperate with the guidance system and is configured to detect a deployment of the surgical device in the subject. A coordination module (22)is configured to receive input from the guidance system and the deployment detector to determine and record one or more of a location and time of each deployment.
摘要翻译：用于医疗装置检测的系统和方法包括构造成将外科装置（32）输送到受试者中的引导系统（38）。手术装置展开检测器（25,40,42,44）构造成与引导系统配合，并被配置成检测被检体内的外科手术装置的部署。配置模块（22）被配置为接收来自引导系统和部署检测器的输入，以确定和记录每个部署的位置和时间中的一个或多个。

9. 发明申请

US20130281839A1 VISUALIZATION OF CATHETER OF THREE-DIMENSIONAL ULTRASOUND 有权
标题翻译：三维超声波导管的可视化
公开(公告)号：US20130281839A1
公开(公告)日：2013-10-24
申请号：US13997800
申请日：2012-01-10
申请人： Pingkun Yan , Vijay Parthasarathy , Robert Manzke , Ameet Kumar Jain
发明人： Pingkun Yan , Vijay Parthasarathy , Robert Manzke , Ameet Kumar Jain
IPC分类号： A61B19/00
CPC分类号： A61B34/20 , A61B6/12 , A61B8/0883 , A61B8/466 , A61B8/483
摘要： An image-guided system employs an X-ray imaging device (20) for generating one or more X-ray images (25, 26) illustrating a tool (41) within an anatomical region (40) and an ultrasound imaging device (30) for generating an ultrasound image (33) illustrating the tool (41) within the anatomical region (40). The image-guided system further employs a tool tracking device (50) for visually tracking the tool (41) within the anatomical region (40). In operation, the tool tracking device (50) localizes a portion of the tool (41) as located within the ultrasound image (33) responsive to an identification of the portion of the tool (41) as located within the X-ray image(s) (25, 26), and executes an image segmentation of an entirety of the tool (41) as located within the ultrasound image (33) relative to a localization of the portion of the tool (41) as located within the ultrasound image (33).
摘要翻译：图像引导系统采用X射线成像装置（20），用于产生示出解剖区域（40）内的工具（41）和超声成像装置（30）的一个或多个X射线图像（25,26）用于产生示出所述解剖区域（40）内的所述工具（41）的超声图像（33）。图像引导系统还采用用于在解剖区域（40）内目视跟踪工具（41）的工具跟踪装置（50）。在操作中，工具跟踪装置（50）响应于位于X射线图像内的工具（41）的部分的识别，使位于超声波图像（33）内的工具（41）的一部分定位 s）（25,26），并且相对于位于超声波图像内的工具（41）的部分的定位，执行位于超声波图像（33）内的整个工具（41）的图像分割（33）。

10. 发明授权

US08363926B2 Systems and methods for modeling three-dimensional objects from two-dimensional images 有权
标题翻译：用于从二维图像建模三维物体的系统和方法
公开(公告)号：US08363926B2
公开(公告)日：2013-01-29
申请号：US12366241
申请日：2009-02-05
申请人： Saad M. Khan , Pingkun Yan , Mubarak Shah
发明人： Saad M. Khan , Pingkun Yan , Mubarak Shah
IPC分类号： G06K9/36 , G06T15/00
CPC分类号： G06T7/564 , G06T7/596 , G06T15/205 , G06T17/00
摘要： In one embodiment, a system and method for modeling a three-dimensional object includes capturing two-dimensional images of the object from multiple different viewpoints to obtain multiple views of the object, estimating slices of the object that lie in parallel planes that cut through the object, and computing a surface of the object from the estimated slices.
摘要翻译：在一个实施例中，用于对三维对象建模的系统和方法包括从多个不同视点捕获对象的二维图像以获得对象的多个视图，估计位于平行平面中的对象的切片对象，并从估计的切片计算对象的表面。

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