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    • 3. 发明申请
    • COBRA GENE AND USES THEREOF
    • COBRA基因及其用途
    • US20050223433A1
    • 2005-10-06
    • US10133985
    • 2002-04-25
    • Philip BenfeyGary Schindelman
    • Philip BenfeyGary Schindelman
    • A01H5/00C07K14/415C12N15/29C12N15/82C12P21/06
    • C07K14/415C12N15/8242C12N15/8261C12N15/8271Y02A40/146
    • A method by which many plants control organ shape is by regulated, differential cellular expansion. A gene involved in regulating the expansion of plants cells, such as Arabidopsis thaliana root cells is COBRA which encodes a protein with a putative GPI anchor. Plants comprising altered root morphologies may be produced by control of COBRA activity. For example, roots which lack COBRA activity comprise thicker, fatter roots (a CORE or cob phenotype) which are well suited for penetrating dense, compacted soil. Plants lacking COBRA activity may be useful in applications wherein plant growth in areas with dense soil would be beneficial. The present invention comprises the Arabidopsis thaliana COBRA gene and COBRA protein and homologues thereof as well as mutated alleles of COBRA. Also provided are anti-COBRA antibodies, transgenic plants which overexpress COBRA and methods for identifying COBRA modulating substances.
    • 许多植物控制器官形状的方法是通过调节的差异细胞扩增。 涉及调节植物细胞扩增的基因,如拟南芥根系细胞是COBRA,其编码具有推定的GPI锚的蛋白质。 包含改变的根形态的植物可以通过控制COBRA活性产生。 例如,缺乏COBRA活性的根包括较厚的,较硬的根(CORE或cob表型),其非常适合于渗透致密的,压实的土壤。 缺乏COBRA活性的植物可能适用于土壤密集区域植物生长有益的应用。 本发明包括拟南芥COBRA基因和COBRA蛋白及其同源物以及COBRA的突变等位基因。 还提供了抗COBRA抗体,过表达COBRA的转基因植物和鉴定COBRA调节物质的方法。