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1. 发明授权

US10166021B2 Wound closure system 有权
公开(公告)号：US10166021B2
公开(公告)日：2019-01-01
申请号：US12839156
申请日：2010-07-19
申请人： Robert C. Wilke , Paul J. Anderson , Douglas Duchon
发明人： Robert C. Wilke , Paul J. Anderson , Douglas Duchon
IPC分类号： A61B17/06 , A61B17/04
摘要： A wound closure system and a method of reducing the size of an open wound are disclosed. A suture line is sutured through body tissue adjacent an open wound, the suture line sutured so as to pass into the body tissue at an entry point and exit at an exit point, the suture line including a plurality of barbs extending outwardly at an acute angle with respect to a surface of the suture line. A biasing member applies a continuous pulling force on the suture line for stretching the body tissue toward the open wound, wherein the biasing member is configured to take up any slack of the suture line during stretching of the body tissue and keep the suture line taut.

2. 发明申请

US20080276576A1 UNIVERSAL TOP SEALING SYSTEM FOR GABLE TOP PACKAGE 有权
标题翻译：通用顶盖密封系统
公开(公告)号：US20080276576A1
公开(公告)日：2008-11-13
申请号：US11745936
申请日：2007-05-08
申请人： Paul J. Anderson
发明人： Paul J. Anderson
IPC分类号： B65B43/26 , B65B7/00
CPC分类号： B65B51/144 , B29C65/02 , B29C66/1122 , B29C66/1312 , B29C66/43122 , B29C66/80 , B29C66/8221 , B29C66/8225 , B29C66/8226 , B29C66/82263 , B29C66/8242 , B29C66/83241 , B29C66/849 , B29L2031/7166 , B65B3/025
摘要： A top sealer for a gable top package having a sealed top fin includes an arm support and a pair of opposing arms pivotally mounted to the arm support. The arms each have a sealing jaw at about an end thereof. The arms are pivotal to move the sealing jaws toward and away from one another through an arc. The arm support is linearly movable toward and away from the package, as the arms pivot, to move the sealing jaws downward, toward the package, to alter the arc of the pivoting sealing jaws.
摘要翻译：用于具有密封顶部翅片的山形顶部包装的顶部密封件包括臂支撑件和可枢转地安装到臂支撑件的一对相对的臂。臂各自在其一端具有密封钳口。臂是枢转的，以通过弧线使密封钳彼此移动并远离彼此。臂支撑件可以朝向和远离包装线性移动，因为臂枢转，以使密封钳向下朝向包装件移动，以改变枢转密封钳口的弧线。

3. 发明授权

US07380389B2 Bottom pre-folder for carton with folded-in gusset tips 有权
标题翻译：用于纸箱的底部预夹，带折叠角撑板提示
公开(公告)号：US07380389B2
公开(公告)日：2008-06-03
申请号：US11379002
申请日：2006-04-17
申请人： Paul J. Anderson
发明人： Paul J. Anderson
IPC分类号： B65B43/26
CPC分类号： B31B50/00 , B31B50/52
摘要： A bottom prefolding assembly prefolds the bottom panels of a package having a bottom wall formed with in-folded gusset tips. The prefolding assembly infolds the bottom gusset panels, leading and trailing panels of a carton and in-folds the gusset panel tips prior to forming the sealed carton bottom. The assembly includes a drive, first and second folding arms configured to contact and inwardly prefold the lead and trailing panels and a forming arm movable with the first and second folding arms. The forming arm has a pair of pivotable finger elements mounted thereto. The finger elements each having a carton engaging portion to engage the panel portions that form the gusset tips and fold the panel portions in a direction opposite of the folding of the gusset panels.
摘要翻译：底部预折叠组件预先折叠具有形成有折叠的角撑板顶端的底壁的包装的底部面板。折叠组件将底部角撑板，纸板的前导面板和后面板折叠，并在形成密封的纸箱底部之前折叠角撑板面板顶部。组件包括驱动器，第一和第二折叠臂，其构造成接触并向内预折叠引线和后板，以及可与第一和第二折叠臂一起移动的成形臂。成形臂具有安装在其上的一对可枢转指状元件。每个手指元件具有纸板接合部分，以接合形成角撑板末端的面板部分，并且在与折叠角撑板面板相反的方向上折叠面板部分。

4. 发明授权

US5837811A Proteins active in lymphocyte-mediated cytotoxicity 失效
标题翻译：淋巴细胞介导的细胞毒活性的蛋白质
公开(公告)号：US5837811A
公开(公告)日：1998-11-17
申请号：US218978
申请日：1994-03-28
申请人： Paul J. Anderson , Michel Streuli , Stuart F. Schlossman
发明人： Paul J. Anderson , Michel Streuli , Stuart F. Schlossman
IPC分类号： C12N15/09 , C07K14/47 , C07K14/705 , C07K16/18 , C07K16/28 , C12Q1/68 , C07K14/00
CPC分类号： C07K14/47 , C07K14/705 , C07K16/18 , C07K16/28
摘要： A purified preparation of a polypeptide that is immunologically reactive with the monoclonal antibody produced by the hybridoma designated ATCC # HB 10319.
摘要翻译：与由命名为ATCC＃HB10319的杂交瘤产生的单克隆抗体具有免疫反应性的多肽的纯化制剂。

5. 发明授权

US5298407A DNA encoding a protein active in lymphocyte-mediated cytotoxicity 失效
标题翻译：编码淋巴细胞介导的细胞毒性活性蛋白的DNA
公开(公告)号：US5298407A
公开(公告)日：1994-03-29
申请号：US726607
申请日：1991-07-10
申请人： Paul J. Anderson , Michel Streuli , Stuart F. Schlossman
发明人： Paul J. Anderson , Michel Streuli , Stuart F. Schlossman
IPC分类号： C07K16/00 , C07K14/435 , C07K14/47 , C07K14/725 , C07K16/18 , C12N15/12 , C12P21/08 , C12Q1/68 , C12R1/91 , G01N33/49 , G01N33/53 , G01N33/577 , C07K13/00 , C12N15/00
CPC分类号： C07K14/47 , C07K16/18
摘要： An isolated DNA that includes a sequence encoding a polypeptide with which the monoclonal antibody TIA-1 produced by the hybridoma designated ATCC#HB10319 is immunologically reactive; a vector or a cell containing such a DNA; and a method of using such a DNA to identify cytolytic lymphocytes.
摘要翻译：分离的DNA，其包含编码多肽的序列，由命名为ATCC＃HB10319的杂交瘤产生的单克隆抗体TIA-1具有免疫反应性; 含有该DNA的载体或细胞; 以及使用这样的DNA来鉴定溶细胞淋巴细胞的方法。

6. 发明授权

US5279294A Medical diagnostic system 失效
标题翻译：医疗诊断系统
公开(公告)号：US5279294A
公开(公告)日：1994-01-18
申请号：US499085
申请日：1990-03-26
申请人： Paul J. Anderson , Ross A. Jessen , David R. Linde , Richard E. Jones , Bert Walter , Paul E. Christenson
发明人： Paul J. Anderson , Ross A. Jessen , David R. Linde , Richard E. Jones , Bert Walter , Paul E. Christenson
IPC分类号： A61B5/151 , A61B5/00 , A61B5/15 , A61B10/00 , C12Q1/54 , G01N33/487 , G01N33/52 , A61B5/14
CPC分类号： C12Q1/54 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150358 , A61B5/150435 , A61B5/150664 , A61B5/15113 , A61B5/15117 , A61B5/15186 , A61B5/1519 , A61B5/15194 , A61B5/157 , G01N33/52 , A61B2560/0252 , A61B2562/0295
摘要： Hand-held shirt-pocket portable instrument for quantitative measurement of glucose or analysis in biological fluids. The system accepts a disposable diagnostic reagent test device which has a reagent carrier and mode of identifying to the instrument the reagent lot characteristics. The instrument includes a housing structure having a visual LCD readout, a microprocessor, and photosensing circuitry which measures the change of color of the reagent carrier upon reaction in the reacting chemistry of the disposable test device. The housing also includes a spring arrangement for actuating a disposable lancet into the skin for generating blood. The disposable diagnostic reagent unit includes a configuration for transporting of the blood in the regent unit. The system includes verification and calibration sequences for the electronics, the chemistry of an unused disposable unit, the presence of a blood sample, and the ambient temperature. The system also provides for storing a plurality of analysis readings.
摘要翻译：用于定量测量葡萄糖或生物液体分析的手提式袖珍便携式仪器。该系统接受一次性诊断试剂测试装置，其具有试剂载体和向仪器鉴定试剂批次特性的模式。仪器包括具有视觉LCD读数的壳体结构，微处理器和光敏电路，其测量在一次性测试装置的反应化学中反应时试剂载体的颜色变化。壳体还包括用于致动一次性刺血针进入皮肤以产生血液的弹簧装置。一次性诊断试剂单元包括用于运送摄取单元中的血液的构造。该系统包括用于电子设备的验证和校准序列，未使用的一次性单元的化学性质，血液样品的存在以及环境温度。该系统还提供存储多个分析读数。

7. 发明授权

US4637403A Glucose medical monitoring system 失效
标题翻译：葡萄糖医疗监护系统
公开(公告)号：US4637403A
公开(公告)日：1987-01-20
申请号：US744539
申请日：1985-06-14
申请人： Fernando S. Garcia , Hartmut Ginnow-Merkert , Paul J. Anderson , Bertram J. Hudson
发明人： Fernando S. Garcia , Hartmut Ginnow-Merkert , Paul J. Anderson , Bertram J. Hudson
IPC分类号： A61B20060101 , A61B5/00 , A61B5/15 , G01N33/48 , G01N33/487 , A61B5/14
CPC分类号： A61B5/157 , A61B5/14532 , A61B5/1455 , A61B5/150022 , A61B5/150099 , A61B5/150404 , A61B5/150435 , A61B5/150511 , A61B5/150519 , A61B5/150786 , A61B5/15107 , A61B5/15111 , A61B5/15117 , A61B5/1519 , A61B5/15194 , C12Q1/006 , A61B2562/0295
摘要： Hand-held shirt-pocket portable medical diagnostic system for checking measurement of blood glucose, urea nitrogen, hemoglobin, blood components or other body qualities. The system includes the engagement of a disposable needle or lance probe package which carries a chemical reagent strip such as blood reacting chemistry. The system includes a pen structure having a visual readout, a microcomputer, and photosensing circuitry which measures the change of color of the blood reacting chemistry of the disposable probe package. The pen also includes a spring arrangement for actuating a needle or lance into the skin for transferring blood from a finger or other area to the chemical reagent strip. A disposable probe structure package includes configurations for transferring of the blood to the reagent strip or the reagent strip to the blood. The pen can also create a vacuum about a time period that the needle is penetrating the skin. The system includes a verification sequence of the electronics, the chemistry of an unused disposable probe package, the presence of blood sample and multiple readings to average results. The system can also be provided with provisions for storing a plurality of readings, communicating with a personal computer, and can act as an alarm and chime to indicate time periods for blood sensing.
摘要翻译：手提式袖珍便携式医疗诊断系统，用于检查血糖，尿素氮，血红蛋白，血液成分或其他身体素质的测量。该系统包括携带化学试剂条（例如血液反应化学物质）的一次性针头或喷枪探针包的接合。该系统包括具有视觉读出器的笔式结构，微型计算机和光敏电路，其测量一次性探头封装的血液反应化学品的颜色变化。该笔还包括用于致动针头或喷枪进入皮肤以将血液从手指或其他区域传送到化学试剂条的弹簧装置。一次性探针结构包装包括用于将血液转移到试剂条或试剂条到血液的构造。笔也可以在针穿透皮肤的时间段内产生真空。该系统包括电子设备的验证序列，未使用的一次性探头包装的化学性质，血液样品的存在和多个读数以获得平均结果。该系统还可以提供用于存储与个人计算机通信的多个读数的设置，并且可以用作警报和钟声以指示血液感测的时间段。

8. 发明授权

US07927352B2 Method of closing a wound using a wound closure product 有权
标题翻译：使用伤口闭合产品闭合伤口的方法
公开(公告)号：US07927352B2
公开(公告)日：2011-04-19
申请号：US12217514
申请日：2008-07-03
申请人： Robert C. Wilke , Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Paul J. Anderson
发明人： Robert C. Wilke , Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Paul J. Anderson
IPC分类号： A61B17/08 , A61D1/00
CPC分类号： A61B90/02 , A61B17/0466 , A61B17/08 , A61B17/083 , A61B2017/0496 , A61B2017/1142 , A61M1/0088
摘要： A wound closure system and a method of closing a wound are disclosed. The wound closure system includes a plurality of skin anchors mechanically attached to external skin tissue around a periphery of a wound, a line extending between the skin anchors, the line slidably engaged with each skin anchor, and a biasing member that provides tension on the line to draw all of the skin anchors toward the wound. The method of closing a wound includes the steps of attaching a plurality of skin anchors to external skin around a periphery of a wound, extending a line between the skin anchors around substantially the entire periphery of the wound, and providing tension to the line to draw the skin anchors toward the wound.
摘要翻译：公开了一种伤口闭合系统和闭合伤口的方法。伤口闭合系统包括多个皮肤锚固件，其机械地连接到围绕伤口的周边的外部皮肤组织，在皮肤锚定件之间延伸的线，与每个皮肤锚固件可滑动地接合的线以及在线上提供张力的偏置构件将所有的皮肤锚定点朝向伤口。关闭伤口的方法包括以下步骤：将多个皮肤锚固件附接到围绕伤口周围的外部皮肤，在围绕伤口的整个周边的皮肤锚固件之间延伸线，并且向线条提供张力以绘制皮肤贴在伤口上。

9. 发明申请

US20100185236A1 WOUND CLOSURE PRODUCT 有权
标题翻译：封闭产品
公开(公告)号：US20100185236A1
公开(公告)日：2010-07-22
申请号：US12750353
申请日：2010-03-30
申请人： Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Paul J. Anderson , Robert C. Wilke
发明人： Daniel M. Elliott , George M. Hoedeman , John J. Berkey , Paul J. Anderson , Robert C. Wilke
IPC分类号： A61B17/04
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/06166 , A61B17/064 , A61B90/02 , A61B2017/0412 , A61B2017/0496 , A61B2017/0618 , A61B2017/081
摘要： A wound closure system and a method of closing a wound are disclosed. The disclosure is directed to a wound closure system comprising a skin anchor mechanically attached to external skin tissue on a first side of a generally linear wound, an anchorable tensioning apparatus mechanically attached to external skin tissue on an opposite side of the wound, and a line extending between the skin anchor and the tensioning apparatus to movably connect the anchor to the tensioning apparatus. The line is fixedly engaged with an anchor on one side of the wound while the tensioning apparatus provides tension on the line to draw the skin anchor and the tensioning apparatus toward each other and toward the wound.
摘要翻译：公开了一种伤口闭合系统和闭合伤口的方法。本发明涉及伤口闭合系统，该伤口闭合系统包括机械连接到大致线性伤口的第一侧上的外部皮肤组织的皮肤锚固体，机械地附接到伤口相对侧上的外部皮肤组织的可锚定张紧装置，以及线在皮肤锚固件和张紧装置之间延伸以将锚固件可移动地连接到张紧装置。该线与伤口的一侧上的锚固体固定地接合，同时张紧装置在线上提供张力，以将皮肤锚定器和张紧装置朝向彼此并朝向伤口。

10. 发明授权

US06269265B1 Apparatus and method for evoking and capturing a sweat sample 有权
标题翻译：用于诱发和捕获汗液样品的装置和方法
公开(公告)号：US06269265B1
公开(公告)日：2001-07-31
申请号：US09510024
申请日：2000-02-22
申请人： Paul J. Anderson
发明人： Paul J. Anderson
IPC分类号： A61N130
CPC分类号： A61N1/30 , A61N1/08
摘要： An apparatus and related method for evoking, capturing, and optionally measuring one or more parameters within a sweat sample on the surface of the skin. The apparatus includes the use of an iontophoresis chemical chamber adapted to evoke a sweat sample, the chemical chamber being matably attached to a skin capsule adapted to contain the evoked sample. The skin capsule, in turn, is provided with one or more sensors to permit the on site determination of a corresponding number of parameters within the sample.
摘要翻译：用于诱发，捕获和任选地测量皮肤表面上的汗样品内的一个或多个参数的装置和相关方法。该装置包括使用适于引起汗液样品的离子电渗化学室，化学室适当地连接到适于容纳诱发样品的皮肤胶囊。皮肤胶囊依次具有一个或多个传感器，以允许现场确定样品内相应数量的参数。

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