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1. 发明公开

EP0739186A1 ULTRASONIC ABLATION OF STENOSES AND OCCLUSIONS WITH IMAGING GUIDANCE 失效
标题翻译：聚合物用于个人护理化妆品产品
公开(公告)号：EP0739186A1
公开(公告)日：1996-10-30
申请号：EP94907815.0
申请日：1994-01-14
申请人： Paul G. Yock and Robert J. Siegel, A joint Venture
发明人： YOCK, Paul, G. , SIEGEL, Robert, J.
IPC分类号： A61B17 , A61B8 , A61B19 , A61F2 , A61M1
摘要： An intraluminal catheter (10) for the ultrasonic ablation of stenoses or occlusions in a body lumen such as peripheral or coronary arteries. The catheter has an elongated ultrasonic probe (15) which can be guided from its proximal end so that the distal tip (16) thereof is positioned into contact or close proximity to the stenotic or occlusive material to be ablated. An imaging system (20) allows for the direct observation of the stenosis or occlusion so that contact with or close proximity of the probe's distal tip to the stenotic or occlusive material is maintained to ensure effective ablation with little or no remnant thereof after the procedure.

2. 发明申请

WO1995019143A1 ULTRASONIC ABLATION OF STENOSES AND OCCLUSIONS WITH IMAGING GUIDANCE 审中-公开
标题翻译：超声造影与成像指导
公开(公告)号：WO1995019143A1
公开(公告)日：1995-07-20
申请号：PCT/US1994000484
申请日：1994-01-14
申请人： PAUL G. YOCK AND ROBERT J. SIEGEL, A JOINT VENTURE
发明人： PAUL G. YOCK AND ROBERT J. SIEGEL, A JOINT VENTURE , YOCK, Paul, G. , SIEGEL, Robert, J.
IPC分类号： A61B17/22
CPC分类号： A61B17/22012 , A61B8/12 , A61B8/445 , A61B8/4488 , A61B2017/00274 , A61B2017/00924 , A61B2017/22014 , A61B2017/22038 , A61B2017/22069 , A61B2017/22072 , A61B2018/00547 , A61B2090/3784 , A61B2217/005 , A61B2217/007 , A61F2002/30093 , A61F2210/0019
摘要： An intraluminal catheter (10) for the ultrasonic ablation of stenoses or occlusions in a body lumen such as peripheral or coronary arteries. The catheter has an elongated ultrasonic probe (15) which can be guided from its proximal end so that the distal tip (16) thereof is positioned into contact or close proximity to the stenotic or occlusive material to be ablated. An imaging system (20) allows for the direct observation of the stenosis or occlusion so that contact with or close proximity of the probe's distal tip to the stenotic or occlusive material is maintained to ensure effective ablation with little or no remnant thereof after the procedure.
摘要翻译：用于超声消融在体腔（例如外周或冠状动脉）中的狭窄或闭塞的管腔内导管（10）。导管具有细长的超声波探头（15），其可以从其近端引导，使得其远端尖端（16）定位成接近或靠近要消融的狭窄或闭塞材料。成像系统（20）允许直接观察狭窄或闭塞，使得保持与探针的远端尖端接触或紧邻狭窄或闭塞性材料，以确保在手术后很少或没有残留的有效消融。

3. 发明授权

US06764450B2 Method and apparatus for intravascular two-dimensional ultrasonography 失效
公开(公告)号：US06764450B2
公开(公告)日：2004-07-20
申请号：US10438111
申请日：2003-05-13
申请人： Paul G. Yock
发明人： Paul G. Yock
IPC分类号： A61B812
CPC分类号： A61B17/320783 , A61B5/02007 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B17/22012 , A61B2017/00924 , A61B2017/22038 , A61B2017/22045 , A61B2017/22052 , A61B2017/22074 , A61B2017/22078 , A61B2090/376 , A61B2090/3784
摘要： A catheter is provided for insertion in the he blood vessel of a patient for ultrasonically imaging the vessel wall. The catheter includes a tubular element and an internally housed drive cable for effective circumferential scan about the catheter of an ultrasonic generating means. Both the tubular element and the drive cable are of a size and flexibility sufficient to permit their introduction into the vessel and subsequent advancement through the vessel to the location of the vessel wall where imaging is desired.

4. 发明授权

US5865178A Method and apparatus for intravascular ultrasonography 失效
标题翻译：血管内超声检查方法与装置
公开(公告)号：US5865178A
公开(公告)日：1999-02-02
申请号：US467178
申请日：1995-06-06
申请人： Paul G. Yock
发明人： Paul G. Yock
IPC分类号： A61B6/00 , A61B8/00 , A61B8/12 , A61B8/14 , A61B17/22 , A61B19/00 , A61M25/00
CPC分类号： A61B17/320783 , A61B17/22012 , A61B5/02007 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B2017/00924 , A61B2017/22038 , A61B2017/22045 , A61B2017/22052 , A61B2017/22074 , A61B2017/22078 , A61B2090/376 , A61B2090/3784
摘要： A catheter is provided for insertion into the blood vessel of a patient for ultrasonically imaging the vessel wall. The catheter includes a tubular element and an internally housed drive cable for effective a circumferential scan about the catheter of an ultrasonic generating means. Both the tubular element and the drive cable are of a size and flexibility sufficient to permit their introduction into the vessel and subsequent advancement through the vessel to the location of the vessel wall where imaging is desired.
摘要翻译：提供导管用于插入病人的血管，以超声成像血管壁。导管包括管状元件和内部容纳的驱动电缆，用于有效地围绕超声波发生装置的导管进行周向扫描。管状元件和驱动电缆都具有足够的尺寸和灵活性，以允许其引入容器并随后通过容器前进到需要成像的容器壁的位置。

5. 发明授权

US5651364A Method and apparatus for intravascular 失效
标题翻译：用于血管内的方法和装置
公开(公告)号：US5651364A
公开(公告)日：1997-07-29
申请号：US468003
申请日：1995-06-06
申请人： Paul G. Yock
发明人： Paul G. Yock
IPC分类号： A61B6/00 , A61B8/00 , A61B8/12 , A61B8/14 , A61B17/22 , A61B19/00 , A61M25/00
CPC分类号： A61B17/320783 , A61B17/22012 , A61B5/02007 , A61B8/12 , A61B8/445 , A61B8/4461 , A61B2017/00924 , A61B2017/22038 , A61B2017/22045 , A61B2017/22052 , A61B2017/22074 , A61B2017/22078 , A61B2090/376 , A61B2090/3784
摘要： A catheter is provided for insertion into the blood vessel of a patient for ultrasonically imaging the vessel wall. The catheter includes a tubular element and an internally housed drive cable for effective a circumferential scan about the catheter of an ultrasonic generating means. Both the tubular element and the drive cable are of a size and flexibility sufficient to permit their introduction into the vessel and subsequent advancement through the vessel to the location of the vessel wall where imaging is desired.
摘要翻译：提供导管用于插入病人的血管，以超声成像血管壁。导管包括管状元件和内部容纳的驱动电缆，用于有效地围绕超声波发生装置的导管进行周向扫描。管状元件和驱动电缆都具有足够的尺寸和灵活性，以允许其引入容器并随后通过容器前进到需要成像的容器壁的位置。

6. 发明授权

US5501227A Angioplasty apparatus facilitating rapid exchange and method 失效
标题翻译：血管成形术装置促进快速交换和方法
公开(公告)号：US5501227A
公开(公告)日：1996-03-26
申请号：US123370
申请日：1993-09-17
申请人： Paul G. Yock
发明人： Paul G. Yock
IPC分类号： A61B18/24 , A61M25/00 , A61M29/02 , A61M25/10
CPC分类号： A61B18/245 , A61M25/0029 , A61M25/104 , A61M2025/0034 , A61M2025/004 , A61M2025/0183 , A61M2025/1093 , A61M25/0021 , A61M25/0032 , A61M25/0045 , A61M25/0071
摘要： Apparatus for introduction into the vessel of a patient comprising a guiding catheter adapted to be inserted into the vessel of the patient and a device adapted to be inserted into the guiding catheter. The device includes a flexible elongate member and a sleeve carried by the flexible elongate member near the distal extremity thereof and extending from a region near the distal extremity to a region spaced from the distal extremity of the flexible elongate element. The device also includes a guide wire adapted to extend through the sleeve so that the guide wire extends rearwardly of the sleeve extending alongside of and exteriorally of the flexible elongate element into a region near the proximal extremity of the flexible elongate element.
摘要翻译：用于引入患者容器的装置，包括适于插入患者血管的引导导管和适于插入引导导管的装置。该装置包括柔性细长构件和由靠近其远端的柔性细长构件承载并且从远端附近的区域延伸到与柔性细长元件的远端间隔开的区域的套筒。该装置还包括适于延伸穿过套筒的引导线，使得导丝线从套筒的后方延伸到柔性细长元件的外部并在外部延伸到靠近柔性细长元件的近端的区域。

7. 发明授权

US06585657B2 Angioplasty apparatus facilitating rapid exchanges 失效
标题翻译：血管成形术装置促进快速交流
公开(公告)号：US06585657B2
公开(公告)日：2003-07-01
申请号：US09906912
申请日：2001-07-16
申请人： Paul G. Yock
发明人： Paul G. Yock
IPC分类号： A61B814
CPC分类号： A61M25/0029 , A61B18/245 , A61M25/0021 , A61M25/0032 , A61M25/0045 , A61M25/0071 , A61M25/104 , A61M2025/0034 , A61M2025/0183 , A61M2025/1093
摘要： The invention provides a nested tubing cannula which comprises outer and inner elongate tubular members, both having a proximal end, a distal end, and a lumen therebetween. The inner tubular member is sealed at its distal end and is nested substantially coaxially within the lumen of the outer tubular member, so that the gap between the inner and the outer tubular member defines a second lumen whereas the first lumen is the lumen of the inner tubular member. A tubular sleeve is disposed coaxially between the inner and outer tubular members. A balloon is mounted on a distal region of the outer tubular member and is in communication with the first lumen. The cannula further comprises a port proximal or distal the balloon occluder and is in communication with the second lumen. Methods for making the devices herein are disclosed.
摘要翻译：本发明提供了一种嵌套管插管，其包括外部和内部细长管状构件，两者均具有近端，远端和其间的内腔。内部管状构件在其远端处被密封并且基本同轴地嵌套在外部管状构件的内腔中，使得内部和外部管状构件之间的间隙限定第二腔，而第一腔是内部管状构件的内腔管状构件。管状套筒同轴地设置在内管状构件和外管状构件之间。气球安装在外部管状构件的远侧区域上并与第一腔连通。套管还包括近端或远端的气囊封堵器并且与第二内腔连通的端口。公开了制造这些装置的方法。

8. 发明授权

US6027450A Treating a totally or near totally occluded lumen 失效
标题翻译：治疗完全或接近完全闭塞的管腔
公开(公告)号：US6027450A
公开(公告)日：2000-02-22
申请号：US368314
申请日：1994-12-30
申请人： Peter S. Brown , Paul G. Yock
发明人： Peter S. Brown , Paul G. Yock
IPC分类号： A61B17/22 , A61B18/00 , A61B19/00 , A61B8/00
CPC分类号： A61B17/320783 , A61B17/320758 , A61B18/00 , A61B2090/3782
摘要： A method and system for recanalizing a totally or near totally occluded body lumen such as an artery which has an elongated catheter shaft with means such as a cutting or ablating element at the distal end of the shaft to remove occluding material and with ultrasonic imaging means preferably located on the shaft proximal to the cutting or ablating element to allow the operator to maintain the radial position of the distal end of the catheter shaft within the body lumen so that no contact is made between the cutting or ablating means and the wall defining the body lumen. The imaging system preferably includes one or more ultrasonic transducers which emit ultrasound in a direction having a substantial radial component, or a substantial axial component or both. Ultrasonic energy reflected from the wall defining the body lumen is received by transducers which generate signals representing the received ultrasonic energy, which in turn are used to form an image of the wall on a video monitor and the radial location of the distal end of the catheter shaft or the means to remove occluding material. The image projected on the video monitor may then be used by the physician to control the position of the distal end of the catheter shaft and/or the means to remove occluding material within the body lumen.
摘要翻译：一种完全或几乎完全闭塞的体腔的方法和系统，例如动脉，该动脉具有细长的导管轴，在轴的远端具有诸如切割或切除元件的装置以去除封闭材料，并且优选使用超声成像装置位于靠近切割或切除元件的轴上，以允许操作者将导管轴的远端的径向位置保持在体腔内，使得在切割或消融装置和限定身体的壁之间不接触流明。成像系统优选地包括一个或多个超声波换能器，其在具有实质的径向分量的方向或相当大的轴向分量或二者上发射超声波。从限定体腔的壁反射的超声能量由换能器接收，换能器产生表示接收到的超声波能量的信号，其又用于在视频监视器上形成壁的图像，并且导管远端的径向位置轴或去除堵塞材料的方法。投影在视频监视器上的图像然后可以被医师用来控制导管轴的远端的位置和/或去除体腔内的封闭材料的装置。

9. 发明授权

US5451233A Angioplasty apparatus facilitating rapid exchanges 失效
公开(公告)号：US5451233A
公开(公告)日：1995-09-19
申请号：US208972
申请日：1994-03-09
申请人： Paul G. Yock
发明人： Paul G. Yock
IPC分类号： A61B18/24 , A61M25/00 , A61M29/02 , A61M25/10
CPC分类号： A61B18/245 , A61M25/0029 , A61M25/104 , A61M2025/0034 , A61M2025/004 , A61M2025/0183 , A61M2025/1093 , A61M25/0021 , A61M25/0032 , A61M25/0045 , A61M25/0071
摘要： Apparatus for introduction into the vessel of a patient comprising a guiding catheter adapted to be inserted into the vessel of the patient and a device adapted to be inserted into the guiding catheter. The device includes a flexible elongate member and a sleeve carried by the flexible elongate member near the distal extremity thereof and extending from a region near the distal extremity to a region spaced from the distal extremity of the flexible elongate element. The device also includes a guide wire adapted to extend through the sleeve so that the guide wire extends rearwardly of the sleeve extending alongside of and exteriorally of the flexible elongate element into a region near the proximal extremity of the flexible elongate element.

10. 发明授权

US5350395A Angioplasty apparatus facilitating rapid exchanges 失效
标题翻译：血管成形术装置促进快速交流
公开(公告)号：US5350395A
公开(公告)日：1994-09-27
申请号：US937977
申请日：1992-11-02
申请人： Paul G. Yock
发明人： Paul G. Yock
IPC分类号： A61B18/24 , A61M25/00 , A61M29/02
CPC分类号： A61B18/245 , A61M25/0029 , A61M25/104 , A61M2025/0034 , A61M2025/004 , A61M2025/0183 , A61M2025/1093 , A61M25/0021 , A61M25/0032 , A61M25/0045 , A61M25/0071
摘要： Apparatus for introduction into the vessel of a patient comprising a guiding catheter adapted to be inserted into the vessel of the patient and a device adapted to be inserted into the guiding catheter. The device includes a flexible elongate member and a sleeve carried by the flexible elongate member near the distal extremity thereof and extending from a region near the distal extremity to a region spaced from the distal extremity of the flexible elongate element. The device also includes a guide wire adapted to extend through the sleeve so that the guide wire extends rearwardly of the sleeve extending alongside of and exteriorally of the flexible elongate element into a region near the proximal extremity of the flexible elongate element.
摘要翻译：用于引入患者容器的装置，包括适于插入患者血管的引导导管和适于插入引导导管的装置。该装置包括柔性细长构件和由靠近其远端的柔性细长构件承载并且从远端附近的区域延伸到与柔性细长元件的远端间隔开的区域的套筒。该装置还包括适于延伸穿过套筒的引导线，使得导丝线从在柔性细长元件的旁边和外部延伸的套筒向后延伸到柔性细长元件的近端附近的区域中。

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