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1. 发明专利

AU6550300A Method of mapping proton transverse relaxation time constants or functions thereof in a target subject to localised movement using nuclear magnetic resonance imaging 未知
公开(公告)号：AU6550300A
公开(公告)日：2001-03-19
申请号：AU6550300
申请日：2000-08-24
申请人： UNIV WESTERN AUSTRALIA , PAUL CLARK
发明人： CLARK PAUL , PIERRE TIMOTHY GUY ST
IPC分类号： A61B5/05 , A61B5/055 , G01R33/20

2. 发明申请

WO2010021936A1 DIGITAL PCR CALIBRATION FOR HIGH THROUGHPUT SEQUENCING 审中-公开
标题翻译：用于高通量测序的数字PCR校准
公开(公告)号：WO2010021936A1
公开(公告)日：2010-02-25
申请号：PCT/US2009/053912
申请日：2009-08-14
申请人： THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY , WHITE, Richard, Allen , BLAINEY, Paul, Clark , FAN, Hei-mun, Christina , QUAKE, Stephen, R.
发明人： WHITE, Richard, Allen , BLAINEY, Paul, Clark , FAN, Hei-mun, Christina , QUAKE, Stephen, R.
IPC分类号： C12P19/34
CPC分类号： C12Q1/6851 , C12Q1/6869 , C12Q2565/629 , C12Q2537/157
摘要： Disclosed is a method for accurately determining the number of template molecules in a library of nucleic acids (e.g., DNA) to be sequenced. The method does not require large amounts of the DNA sample, nor does it require the preparation of a standard curve. The method is especially applicable to methodologies for "sequencing by synthesis," where quantitation of the starting library is important. The method uses quantitative real time PCR, especially digital PCR, which measures the number of individual molecules in a sample. The present method particularly may use a microfluidic device for running large numbers of PCR reactions. Each PCR reaction is monitored in real time by a primer/probe combination. The forward primer is adapted to contain a sequence not on the adapter but which corresponds to a probe sequence. A short probe which generates fluorescence during the PCR process is used.
摘要翻译：公开了一种精确测定待测序的核酸文库（例如DNA）中模板分子数目的方法。该方法不需要大量的DNA样品，也不需要制备标准曲线。该方法特别适用于“通过合成测序”的方法，其中起始文库的定量是重要的。该方法使用定量实时PCR，特别是数字PCR，其测量样品中各个分子的数量。本方法特别可以使用微流体装置进行大量的PCR反应。通过引物/探针组合实时监测每个PCR反应。正向引物适于包含不在适配器上但是对应于探针序列的序列。使用在PCR过程中产生荧光的短探针。

3. 发明申请

WO2018048896A1 INTELLIGENT LIGHTING CONTROL SYSTEM LINE VOLTAGE DETECTION APPARATUSES, SYSTEMS, AND METHODS 审中-公开
标题翻译：智能照明控制系统线路电压检测装置，系统和方法
公开(公告)号：WO2018048896A1
公开(公告)日：2018-03-15
申请号：PCT/US2017/050273
申请日：2017-09-06
申请人： EDWARDS, Paul Clark , LARK, William, Jr. , CHARLTON, Erik Allen
发明人： EDWARDS, Paul Clark , LARK, William, Jr. , CHARLTON, Erik Allen
IPC分类号： H05B37/02
CPC分类号： H05B37/0272 , G08C17/02 , H05B33/08 , H05B33/0809 , H05B37/0209 , H05B37/0218 , H05B37/0227
摘要： The present disclosure provides an intelligent lighting control system. A detector circuit of a lighting control module detects a line voltage of an electrical line connected to a power terminal of the light control module. The lighting control module is configured to cause a transmission of a quantity of electrical energy to a lighting circuit of a light fixture electrically connected to the lighting control module. The lighting control module reduces a flow of electricity transmitted to the lighting circuit to turn off the respective light fixture in response to detecting substantially no change in the line voltage over a pre-specified period of time.
摘要翻译：本公开提供了一种智能照明控制系统。照明控制模块的检测器电路检测连接到光控制模块的电源端子的电线的线电压。照明控制模块被配置为使电能量传输到电连接到照明控制模块的灯具的照明电路。响应于在预先指定的时间段内基本上检测不到线路电压的变化，照明控制模块减少传输到照明电路的电流以关闭相应的灯具。

4. 发明授权

US09230055B2 Method of optimizing film cooling performance for turbo-machinery components 有权
标题翻译：优化涡轮机械部件薄膜冷却性能的方法
公开(公告)号：US09230055B2
公开(公告)日：2016-01-05
申请号：US13440336
申请日：2012-04-05
申请人： John Paul Clark , Jamie Jay Johnson , Michael Kenneth Ooten
发明人： John Paul Clark , Jamie Jay Johnson , Michael Kenneth Ooten
IPC分类号： G06F17/50
CPC分类号： G06F17/5086 , G06F17/5018 , G06F2217/16
摘要： A method, apparatus and program product are provided to optimize film cooling performance for turbomachinery components. A design space is defined by selecting process variables and limits. A random initial population of a plurality of designs is provided using Latin hypersquare sampling, varying the process variables across the design space. Each design of the plurality of designs is evaluated. A fitness function value is determined based on a performance of each of the evaluated designs of the plurality of designs. A half of the plurality of designs having higher fitness function values is selected. Designs of the selected half of the plurality of designs are randomly paired to generate two new designs from each random pair of designs forming a plurality of new designs.
摘要翻译：提供了一种方法，装置和程序产品，以优化涡轮机组件的薄膜冷却性能。通过选择过程变量和限制来定义设计空间。使用拉丁超像素采样提供多个设计的随机初始群体，改变跨设计空间的过程变量。评估多个设计的每个设计。基于多个设计的评估设计中的每一个的性能来确定适应度函数值。选择具有较高适应度函数值的多个设计中的一半。多个设计的所选择的一半的设计是随机配对的，以从形成多个新设计的每个随机设计对中产生两个新的设计。

5. 发明授权

US08337833B2 Methods of improving central nervous system functioning 有权
标题翻译：改善中枢神经系统功能的方法
公开(公告)号：US08337833B2
公开(公告)日：2012-12-25
申请号：US12778006
申请日：2010-05-11
申请人： Morey Kraus , Seth Finklestein , Paul Clark
发明人： Morey Kraus , Seth Finklestein , Paul Clark
IPC分类号： A01N63/00 , A01N65/00 , A61K35/12 , A61K35/14 , C12N5/071
CPC分类号： A61K35/51 , A61K35/14 , A61K35/28 , A61K38/18 , A61K38/1808 , A61K38/1825 , A61K38/1841 , A61K38/1858 , A61K38/1866 , A61K38/20 , A61K2300/00
摘要： Methods of causing an improvement in central nervous system function are provided. The methods include administering an aliquot of stem cells to the patient, the cells being derived from blood, e.g., umbilical cord blood. In some cases a growth factor is administered with the cells.
摘要翻译：提供了改善中枢神经系统功能的方法。所述方法包括向患者施用等分的干细胞，所述细胞衍生自血液，例如脐带血。在一些情况下，与细胞一起施用生长因子。

6. 发明授权

US07960759B2 Integrated circuit layout pattern for cross-coupled circuits 有权
标题翻译：交叉耦合电路的集成电路布局图
公开(公告)号：US07960759B2
公开(公告)日：2011-06-14
申请号：US12285795
申请日：2008-10-14
申请人： Marlin Wayne Frederick , David Paul Clark
发明人： Marlin Wayne Frederick , David Paul Clark
IPC分类号： H01L23/52
CPC分类号： H01L27/0207 , H01L29/4238
摘要： A circuit 32 is provided comprising a first diffusion region 34 and a parallel second diffusion region 36. A sequence of N gate layers 40, 42, 46 is provided with a first and an Nth of these gate layers covering different respective ones of the diffusion regions 34, 36 whilst the middle (N−2) gate layers 42 cover both diffusion regions 34, 36. A bridging conductor 64 connects the first gate layer 40 and the Nth gate layer 46. In some embodiments, the second diffusion region is provided as two second diffusion sub-regions 68, 70 having a diffusion region gap 74 therebetween and electrically connected via a jumper connector 42. A first gate layer 76 which forms a gate electrode with a first diffusion region 66 can extend through this diffusion region gap 74 not forming a gate electrode therewith and facilitating use of a collinear bridging conductor 82 to connect to the Nth gate layer 80.
摘要翻译：提供了包括第一扩散区域34和平行的第二扩散区域36的电路32.一系列N个栅极层40,42,46设置有覆盖不同的各个扩散区域的第一和第N栅极层中间（N-2）栅极层42覆盖扩散区34,36。桥接导体64连接第一栅极层40和第N栅极层46.在一些实施例中，第二扩散区域被提供为两个第二扩散子区域68,70在其间具有扩散区间隙74并通过跳线连接器42电连接。形成具有第一扩散区域66的栅电极的第一栅极层76可以延伸穿过该扩散区间隙74 与其形成栅电极，并且便于使用共线桥接导体82连接到第N栅极层80。

7. 发明授权

US07294512B2 Solution for calibrating a chemical analyzer for alcohol, carbonate and ammonia assays 有权
标题翻译：用于校准酒精，碳酸盐和氨测定的化学分析仪的解决方案
公开(公告)号：US07294512B2
公开(公告)日：2007-11-13
申请号：US11495423
申请日：2006-07-28
申请人： Douglas Paul Clark
发明人： Douglas Paul Clark
IPC分类号： G01N21/93
CPC分类号： G01N33/96 , Y10T436/10 , Y10T436/106664 , Y10T436/108331 , Y10T436/175383 , Y10T436/204165 , Y10T436/204998
摘要： A multi-analyte calibration solution having known amounts of sodium carbonate, ammonium bicarbonate, and ethyl alcohol, with pH adjusted within a range between about 7.8 and 8.4.
摘要翻译：具有已知量的碳酸钠，碳酸氢铵和乙醇的多分析物校准溶液，pH调节在约7.8和8.4之间。

8. 发明申请

US20070252466A1 Electrical machines with reduced cogging 有权
标题翻译：电机齿轮减少
公开(公告)号：US20070252466A1
公开(公告)日：2007-11-01
申请号：US11787724
申请日：2007-04-17
申请人： Paul Clark
发明人： Paul Clark
IPC分类号： H02K21/12 , H02K1/00 , H02K1/27
CPC分类号： H02K29/03 , H02K1/278 , H02K21/14
摘要： The present invention provides an electrical machine 1 with reduced cogging. The magnet poles 3 of the electrical machine are comprised of at least two separate groups of at least two circumferentially adjacent magnet poles. One of the circumferentially outer magnet poles 3 in one of the groups of magnet poles is defined as being in its reference position. The reference position of each other magnet pole 3 is defined as the position each other magnet pole would occupy if all the magnet poles were equally circumferentially spaced around the first or second body and the one circumferentially outer pole was in its reference position. At least one of the circumferentially outer magnet poles 3 in each group is sited in its reference position. At least one magnet pole 3 in each group is a displaced magnet pole and is sited in a position that is displaced from its reference position by an amount that is not equal to an integral multiple of the reference angular pitch of the winding slots. The displacement of the magnet poles 3 provides a pronounced reduction in cogging.
摘要翻译：本发明提供一种减少齿槽的电机1。电机的磁极3由至少两个分开的至少两个周向相邻的磁极组组成。一组磁极中的一个周向外磁极3被定义为处于其参考位置。每个其他磁极3的参考位置被定义为如果所有磁极在第一或第二主体周围均匀地周向间隔并且一个周向外极处在其参考位置时，彼此磁极将占据的位置。每组中的周向外磁极3中的至少一个位于其参考位置。每个组中的至少一个磁极3是位移磁极，并且位于从其基准位置偏移不等于绕组槽的基准角距的整数倍的位置的位置。磁极3的位移提供了明显的齿槽减少。

9. 发明申请

US20070194040A1 Composition and Aerosol Spray Dispenser for Eliminating Odors in Air 有权
标题翻译：用于消除空气中气味的成分和气溶胶喷雾分配器
公开(公告)号：US20070194040A1
公开(公告)日：2007-08-23
申请号：US11681043
申请日：2007-03-01
申请人： Maciej Tasz , Leon Samuelson , M. Roshier , Richard Valpey , Paul Clark , Jessica Heiser , Kendra Haag
发明人： Maciej Tasz , Leon Samuelson , M. Roshier , Richard Valpey , Paul Clark , Jessica Heiser , Kendra Haag
IPC分类号： B01F3/04
CPC分类号： A61L9/14 , A61L9/01 , A61L9/145 , A61L2209/134 , A61L2209/22 , B65D83/48
摘要： An air treating composition for eliminating airborne malodors and/or sanitizing air in combination with a spray valve and actuator and spray performance parameters providing maximum dispersion of the composition is disclosed. The particles of the composition are small so that the active component is dispersed into air as a fine dispersion to provide more contact with malodors and to provide quick absorption of malodors and/or bacteria. The particle size of the composition is controlled through the valve and actuator dimensions, as well as the formulation requirements of the composition. The air treating composition includes water, a low molecular weight polyol, and a propellant The composition may also include one or more adjuvants such as an emulsifier, a co-solvent, a fragrance, a corrosion inhibitor, a pH adjusting agent and the like.
摘要翻译：公开了一种用于消除空气恶臭和/或消毒空气的空气处理组合物，其结合喷雾阀和致动器以及提供组合物的最大分散性的喷雾性能参数。组合物的颗粒小，使得活性组分作为细分散体分散在空气中以提供与恶臭的更多接触并提供对恶臭和/或细菌的快速吸收。组合物的粒度通过阀门和致动器尺寸以及组合物的配方要求来控制。空气处理组合物包括水，低分子量多元醇和推进剂。组合物还可以包括一种或多种助剂，例如乳化剂，助溶剂，香料，缓蚀剂，pH调节剂等。

10. 发明授权

US07222444B2 Coordinated linkage system for a work vehicle 有权
标题翻译：工作车辆的协调联动系统
公开(公告)号：US07222444B2
公开(公告)日：2007-05-29
申请号：US10970622
申请日：2004-10-21
申请人： Scott Svend Hendron , Judson Paul Clark
发明人： Scott Svend Hendron , Judson Paul Clark
IPC分类号： E02F5/02
CPC分类号： E02F3/436 , E02F3/432 , E02F3/964
摘要： A work vehicle with a tool pivotally attached to a linkage, an actuator for controllably moving the tool about its pivot, and a tilt angle sensor for sensing the absolute angle of the work tool relative to the earth. A controller is adapted to perform an auto-hold function for the tool, automatically maintaining an initial tool orientation by commanding movement of the tool actuator to hold the work tool at about the initial or set absolute angle of the tool. The controller is adapted to discontinue the tool auto-hold function when the operator manipulates a tool command input device affecting tool actuator movement, and resume the tool auto-hold function at the new orientation affected by the operator. Manipulation of an auto-hold command input device allows the operator to selectively enable and disable the tool auto-hold function.
摘要翻译：具有可枢转地附接到联动装置的工具的工作车辆，用于围绕其枢轴可控地移动工具的致动器以及用于感测作业工具相对于地球的绝对角度的倾斜角度传感器。控制器适于对工具执行自动保持功能，通过指令工具致动器的运动来自动保持初始刀具定向，以将工件保持在大约工具的初始或设定的绝对角度。当操作员操作影响刀具执行器运动的刀具命令输入装置时，控制器适用于中止刀具自动保持功能，并在受操作者影响的新方向恢复刀具自动保持功能。自动保持命令输入设备的操作允许操作员选择性地启用和禁用工具自动保持功能。

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