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1. 发明授权

US06230683B1 Premixed charge compression ignition engine with optimal combustion control 有权
标题翻译：具有最佳燃烧控制的预混合充气压缩点火式发动机
公开(公告)号：US06230683B1
公开(公告)日：2001-05-15
申请号：US09456382
申请日：1999-12-08
申请人： Axel O. zur Loye , Omowoleola C. Akinyemi , Russ P. Durrett , Patrick F. Flynn , Gary L. Hunter , Greg A. Moore , Jackie M. Mudd , George G. Muntean , Julie A. Wagner , John F. Wright
发明人： Axel O. zur Loye , Omowoleola C. Akinyemi , Russ P. Durrett , Patrick F. Flynn , Gary L. Hunter , Greg A. Moore , Jackie M. Mudd , George G. Muntean , Julie A. Wagner , John F. Wright
IPC分类号： F02B306
CPC分类号： F02D13/028 , F02B1/12 , F02B3/06 , F02B19/14 , F02B29/0406 , F02B37/04 , F02B37/18 , F02B2075/025 , F02B2275/32 , F02D13/0203 , F02D13/0215 , F02D13/0234 , F02D13/0265 , F02D13/0269 , F02D15/04 , F02D19/0605 , F02D19/0649 , F02D19/0665 , F02D19/081 , F02D35/023 , F02D35/028 , F02D41/0025 , F02D41/0087 , F02D41/3029 , F02D41/3035 , F02D41/3041 , F02D41/3076 , F02D41/38 , F02D2013/0292 , F02M26/01 , F02M26/04 , F02M26/07 , F02M26/08 , F02M26/23 , F02M26/28 , F02M26/33 , F02M26/43 , F02M31/02 , F02M31/20 , F02P19/00 , Y02T10/12 , Y02T10/125 , Y02T10/126 , Y02T10/128 , Y02T10/142 , Y02T10/36 , Y02T10/42
摘要： A premixed charge compression ignition engine, and a control system, is provided which effectively initiates combustion by compression ignition and maintains stable combustion while achieving extremely low nitrous oxide emissions, good overall efficiency and acceptable combustion noise and cylinder pressures. The present engine and control system effectively controls the combustion history, that is, the time at which combustion occurs, the rate of combustion, the duration of combustion and/or the completeness of combustion, by controlling the operation of certain control variables providing temperature control, pressure control, control of the mixture's autoignition properties and equivalence ratio control. The combustion control system provides active feedback control of the combustion event and includes a sensor, e.g. pressure sensor, for detecting an engine operating condition indicative of the combustion history, e.g. the start of combustion, and generating an associated engine operating condition signal. A processor receives the signal and generates control signals based on the engine operating condition signal for controlling various engine components to control the temperature, pressure, equivalence ratio and\or autoignition properties so as to variably control the combustion history of future combustion events to achieve stable, low emission combustion in each cylinder and combustion balancing between the cylinders.
摘要翻译：提供了预混合充气压缩点火发动机和控制系统，其通过压缩点火有效启动燃烧，并保持稳定的燃烧，同时实现极低的一氧化二氮排放，良好的总体效率和可接受的燃烧噪声和气缸压力。本发动机和控制系统通过控制提供温度控制的某些控制变量的操作来有效地控制燃烧历史，即燃烧发生时间，燃烧速率，燃烧持续时间和/或燃烧完整性，压力控制，混合物自燃特性控制和当量比控制。燃烧控制系统提供对燃烧事件的主动反馈控制，并且包括传感器，例如，压力传感器，用于检测指示燃烧历史的发动机运行状态，例如，燃烧开始，并产生相关联的发动机运转状态信号。处理器接收信号并根据发动机工作条件信号产生控制信号，用于控制各种发动机部件以控制温度，压力，当量比和/或自燃特性，以便可变地控制未来燃烧事件的燃烧历史以达到稳定，每个气缸中的低排放燃烧和气缸之间的燃烧平衡。

2. 发明授权

US4227855A Turbomachine 失效
标题翻译：涡轮机
公开(公告)号：US4227855A
公开(公告)日：1980-10-14
申请号：US936695
申请日：1978-08-25
申请人： Patrick F. Flynn , Harold G. Weber , John M. Mulloy
发明人： Patrick F. Flynn , Harold G. Weber , John M. Mulloy
IPC分类号： F01D5/04 , F04D29/28
CPC分类号： F01D5/043 , F01D5/048 , F04D29/284
摘要： A turbomachine for a compressible fluid is provided which includes a compressor wheel having a plurality of vanes extending from a generally axial flow inlet to a generally radial flow outlet. Adjacent vanes define fluid passageways having a generally axially oriented section near the inlet and a generally radially oriented section near the outlet. Located substantially within the generally radially oriented sections of a predetermined number of passageways is a reference station which has a configuration such that the mean tangential dimension of said passageway at said reference station is no more than about 60% of the circumference of the rotor at that mean radius divided by the number of vanes at that radius. Each reference station serves to effect substantial attachment of the flowing fluid to the surfaces defining said passageway, particularly at low mass flow, and, thus, broaden the usable flow range of the compressor.
摘要翻译：提供了一种用于可压缩流体的涡轮机，其包括具有多个叶片的压缩机叶轮，所述多个叶片从大致轴向的流动入口延伸到大致径向的流动出口。相邻的叶片限定在入口附近具有大致轴向定向的部分的流体通道和靠近出口的大致径向定向的部分。基本上位于预定数量的通道的通常径向定向的部分内的是具有这样一种构造的参考站，所述构造使得在所述参考站处的所述通道的平均切向尺寸不超过所述转子圆周的大约60％平均半径除以该半径处的叶片数。每个参考站用于实质上将流动的流体附着到限定所述通道的表面，特别是在低质量流动下，从而扩大压缩机的可用流量范围。

3. 发明授权

US4218456A 1-(4-Fluorophenyl)-4-(1,2,3,6-tetrahydro-4-phenoxy-1-pyridinyl)-butanones 失效
标题翻译： 1-（4-氟苯基）-4-（1,2,3,6-四氢-4-苯氧基-1-吡啶基） - 丁酮
公开(公告)号：US4218456A
公开(公告)日：1980-08-19
申请号：US922512
申请日：1978-07-10
申请人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
发明人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
IPC分类号： C07D211/74 , A61K31/44 , C07D213/04
CPC分类号： C07D211/74
摘要： Tetrahydropyridylbutyrophenones of the following formula I: ##STR1## wherein x is hydrogen, halogen such as fluorine, chlorine, bromine or iodine, trifluoromethyl, alkoxy, thioalkoxy, nitro, cyano, amino, lower alkyl of 1 to 6 carbons, aryl or substituted aryl; and y is hydrogen or halogen; and the non-toxic, pharmaceutically acceptable acid addition salts thereof. The compounds of the invention having the formula I are useful in the treatment of psychotic disorders such as schizophrenia.
摘要翻译：下式I的四氢吡啶基丁酰苯：其中x是氢，卤素如氟，氯，溴或碘，三氟甲基，烷氧基，硫代烷氧基，硝基，氰基，氨基，1-6个碳的低级烷基，芳基或取代芳基; 和y是氢或卤素; 和其无毒的药学上可接受的酸加成盐。具有式I的本发明化合物可用于治疗精神病如精神分裂症。

4. 发明授权

US3977376A Diesel engine intake air preheater fuel control 失效
标题翻译：柴油发动机采用空气预热器燃油控制
公开(公告)号：US3977376A
公开(公告)日：1976-08-31
申请号：US523719
申请日：1974-11-14
申请人： David L. Reid , Patrick F. Flynn , Walter Wayne Eberhard
发明人： David L. Reid , Patrick F. Flynn , Walter Wayne Eberhard
IPC分类号： F02B3/06 , F02M31/04 , F02N19/04 , F02M31/00
CPC分类号： F02N19/04 , F02M31/042 , F02B3/06 , Y02T10/126
摘要： A metering and control system is described for supplying fuel to a burner nozzle of a burner assembly which preheats intake air in a diesel engine. Fuel for the control system is derived from the regulated pressure output of a fuel pump in the engine fuel supply system. The fuel metering and control system includes a series of parallel flow lines connected between the fuel pump and the burner nozzle. Each line has a metering orifice and check valve set to pass flow above a given pressure level. For intermediate rpm flow is through one line and at high rpm flow is through both. As a result, the fuel flow rate into the burner nozzle is directly proportional to engine rpm to provide a uniform nozzle preheat temperature over the full range of engine rpm. Suitable control inputs are provided to initiate or terminate flow to the burner in response to selected engine operating parameters. In addition, supplemental fuel flow may be provided during start up and/or cold operating conditions, again initiated or terminated by selected engine operating parameters.

5. 发明授权

US06276334B1 Premixed charge compression ignition engine with optimal combustion control 有权
标题翻译：具有最佳燃烧控制的预混合充气压缩点火式发动机
公开(公告)号：US06276334B1
公开(公告)日：2001-08-21
申请号：US09255780
申请日：1999-02-23
申请人： Patrick F. Flynn , Gary L. Hunter , Axel O. zur Loye , Omowoleola C. Akinyemi , Russ P. Durrett , Greg A. Moore , George G. Muntean , Lester L. Peters , Patrick M. Pierz , Julie A. Wagner , John F. Wright , Jackie M. Yeager
发明人： Patrick F. Flynn , Gary L. Hunter , Axel O. zur Loye , Omowoleola C. Akinyemi , Russ P. Durrett , Greg A. Moore , George G. Muntean , Lester L. Peters , Patrick M. Pierz , Julie A. Wagner , John F. Wright , Jackie M. Yeager
IPC分类号： F02M700
CPC分类号： F02D13/0215 , F01L1/146 , F01L1/181 , F01L1/352 , F01L9/02 , F01L2001/34486 , F01P2003/021 , F01P2060/02 , F02B1/12 , F02B1/14 , F02B3/06 , F02B19/14 , F02B29/00 , F02B29/0412 , F02B29/0418 , F02B29/0493 , F02B33/443 , F02B37/04 , F02B37/18 , F02B75/02 , F02B2075/025 , F02B2075/027 , F02B2275/32 , F02D9/04 , F02D13/0203 , F02D13/0249 , F02D13/0257 , F02D13/0265 , F02D13/0269 , F02D13/0273 , F02D13/0276 , F02D13/028 , F02D15/04 , F02D19/0605 , F02D19/061 , F02D19/0647 , F02D19/0649 , F02D19/0692 , F02D19/08 , F02D19/12 , F02D35/02 , F02D35/023 , F02D35/028 , F02D41/0025 , F02D41/008 , F02D41/0085 , F02D41/3035 , F02D41/3041 , F02D41/38 , F02D41/403 , F02D2041/001 , F02D2041/389 , F02D2200/0414 , F02G2243/24 , F02G2250/24 , F02M25/00 , F02M25/0227 , F02M25/028 , F02M25/03 , F02M26/01 , F02M26/07 , F02M26/08 , F02M26/23 , F02M26/33 , F02M26/615 , F02M31/02 , F02M31/042 , F02P19/00 , Y02T10/12 , Y02T10/125 , Y02T10/126 , Y02T10/128 , Y02T10/14 , Y02T10/142 , Y02T10/144 , Y02T10/146 , Y02T10/36 , Y02T10/42
摘要： A premixed charge compression ignition engine, and a control system, is provided which effectively initiates combustion by compression ignition and maintains stable combustion while achieving extremely low oxides of nitrogen emissions, good overall efficiency and acceptable combustion noise and cylinder pressures. The present engine and control system effectively controls the combustion history, that is, the time at which combustion occurs, the rate of combustion, the duration of combustion and/or the completeness of combustion, by controlling the operation of certain control variables providing temperature control, pressure control, control of the mixture's autoignition properties and equivalence ratio control. The combustion control system provides active feedback control of the combustion event and includes a sensor, e.g. pressure sensor, for detecting an engine operating condition indicative of the combustion history, e.g. the start of combustion, and generating an associated engine operating condition signal. A processor receives the signal and generates control signals based on the engine operating condition signal for controlling various engine components to control the temperature, pressure, equivalence ratio and/or autoignition properties so as to variably control the combustion history of future combustion events to achieve stable, low emission combustion in each cylinder and combustion balancing between the cylinders.
摘要翻译：提供了预混合充气压缩点火发动机和控制系统，其通过压缩点火有效地启动燃烧并保持稳定的燃烧，同时实现极低的氮氧化物排放，良好的总体效率和可接受的燃烧噪声和气缸压力。本发动机和控制系统通过控制提供温度控制的某些控制变量的操作来有效地控制燃烧历史，即燃烧发生时间，燃烧速率，燃烧持续时间和/或燃烧完整性，压力控制，混合物自燃特性控制和当量比控制。燃烧控制系统提供对燃烧事件的主动反馈控制，并且包括传感器，例如。压力传感器，用于检测指示燃烧历史的发动机运行状态，例如，燃烧开始，并产生相关联的发动机运转状态信号。处理器接收信号并基于发动机运转状态信号产生控制信号，以控制各种发动机部件，以控制温度，压力，当量比和/或自燃特性，以便可变地控制未来燃烧事件的燃烧历史以达到稳定，每个气缸中的低排放燃烧和气缸之间的燃烧平衡。

6. 发明授权

US4128552A 1-[4,4-Bis(4-fluorophenyl)butyl]-4-phenylthio-1,2,3,6 -tetrahydropyridines and related sulfoxides and sulfones 失效
标题翻译： 1- {8,4-二（4-氟苯基）丁基{9,4-苯硫基-1,2,3,6-四氢吡啶类和相关的亚砜和砜
公开(公告)号：US4128552A
公开(公告)日：1978-12-05
申请号：US836866
申请日：1977-09-26
申请人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
发明人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
IPC分类号： C07D211/72 , C07D213/04
CPC分类号： C07D211/72
摘要： Diphenylbutyltetrahydropyridines of the following formula: ##STR1## are disclosed, in which X is hydrogen, halogen such as fluorine, chlorine or bromine, trifluoromethyl, alkoxy, nitro, amino, lower alkyl of 1 to 6 carbon atoms, aryl or substituted aryl and n is 0, 1 or 2. These compounds are useful as antipsychotics.
摘要翻译：公开了下式的二苯基丁基四氢吡啶：其中X是氢，卤素如氟，氯或溴，三氟甲基，烷氧基，硝基，氨基，1至6个碳原子的低级烷基，芳基或取代的芳基和 n是0,1或2.这些化合物可用作抗精神病药。

7. 发明授权

US06286482B1 Premixed charge compression ignition engine with optimal combustion control 失效
标题翻译：具有最佳燃烧控制的预混合充气压缩点火式发动机
公开(公告)号：US06286482B1
公开(公告)日：2001-09-11
申请号：US08916437
申请日：1997-08-22
申请人： Patrick F. Flynn , Gary L. Hunter , Axel O. zur Loye , Omowoleoia C. Akinyemi , Russ P. Durrett , Greg A. Moore , Jackie M. Mudd , George G. Muntean , Julie A. Wagner , John F. Wright
发明人： Patrick F. Flynn , Gary L. Hunter , Axel O. zur Loye , Omowoleoia C. Akinyemi , Russ P. Durrett , Greg A. Moore , Jackie M. Mudd , George G. Muntean , Julie A. Wagner , John F. Wright
IPC分类号： F02M700
CPC分类号： F02D41/3029 , F02B1/12 , F02B3/06 , F02B19/14 , F02B2075/025 , F02B2275/32 , F02D13/0203 , F02D13/0215 , F02D13/0261 , F02D13/0269 , F02D15/04 , F02D19/0649 , F02D35/023 , F02D41/0025 , F02D41/3035 , F02D41/3041 , F02D41/38 , F02D2013/0292 , F02M26/01 , F02M26/07 , F02M26/08 , F02M26/23 , F02M26/28 , F02M26/33 , F02M26/43 , F02M31/02 , F02M31/20 , F02P19/00 , Y02T10/12 , Y02T10/125 , Y02T10/126 , Y02T10/128 , Y02T10/142 , Y02T10/36 , Y02T10/42
摘要： A premixed charge compression ignition engine, and a control system, is provided which effectively initiates combustion by compression ignition and maintains stable combustion while achieving extremely low oxides of nitrogen emissions, good overall efficiency and acceptable combustion noise and cylinder pressures. The present engine and control system effectively controls the combustion history, that is, the time at which combustion occurs, the rate of combustion, the duration of combustion and/or the completeness of combustion, by controlling the operation of certain control variables providing temperature control, pressure control, control of the mixture's autoignition properties and equivalence ratio control. The combustion control system provides active feedback control of the combustion event and includes a sensor, e.g. pressure sensor, for detecting an engine operating condition indicative of the combustion history, e.g. the start of combustion, and generating an associated engine operating condition signal. A processor receives the signal and generates control signals based on the engine operating condition signal for controlling various engine components to control the temperature, pressure, equivalence ratio and\or autoignition properties so as to variably control the combustion history of future combustion events to achieve stable, low emission combustion in each cylinder and combustion balancing between the cylinders.
摘要翻译：提供了预混合充气压缩点火发动机和控制系统，其通过压缩点火有效地启动燃烧并保持稳定的燃烧，同时实现极低的氮氧化物排放，良好的总体效率和可接受的燃烧噪声和气缸压力。本发动机和控制系统通过控制提供温度控制的某些控制变量的操作来有效地控制燃烧历史，即燃烧发生时间，燃烧速率，燃烧持续时间和/或燃烧完整性，压力控制，混合物自燃特性控制和当量比控制。燃烧控制系统提供对燃烧事件的主动反馈控制，并且包括传感器，例如。压力传感器，用于检测指示燃烧历史的发动机运行状态，例如，燃烧开始，并产生相关联的发动机运转状态信号。处理器接收信号并根据发动机工作条件信号产生控制信号，用于控制各种发动机部件以控制温度，压力，当量比和/或自燃特性，以便可变地控制未来燃烧事件的燃烧历史以达到稳定，每个气缸中的低排放燃烧和气缸之间的燃烧平衡。

8. 发明授权

US06915776B2 Premixed charge compression ignition engine with optimal combustion control 失效
标题翻译：具有最佳燃烧控制的预混合充气压缩点火式发动机
公开(公告)号：US06915776B2
公开(公告)日：2005-07-12
申请号：US10684560
申请日：2003-10-15
申请人： Axel O. zur Loye , Omowoleoa C. Akinyemi , Russ P. Durrett , Patrick F. Flynn , Gary L. Hunter , Greg A. Moore , Jackie M. Mudd , George G. Muntean , Julie A. Wagner , John F. Wright
发明人： Axel O. zur Loye , Omowoleoa C. Akinyemi , Russ P. Durrett , Patrick F. Flynn , Gary L. Hunter , Greg A. Moore , Jackie M. Mudd , George G. Muntean , Julie A. Wagner , John F. Wright
IPC分类号： F02B1/12 , F02B3/06 , F02B19/14 , F02B75/02 , F02D13/02 , F02D15/04 , F02D19/06 , F02D41/00 , F02D41/30 , F02D41/38 , F02M25/07 , F02M31/02 , F02M31/20 , F02P19/00 , F02M43/00
CPC分类号： F02D13/028 , F02B1/12 , F02B3/06 , F02B19/14 , F02B29/0406 , F02B37/04 , F02B37/18 , F02B2075/025 , F02B2275/32 , F02D13/0203 , F02D13/0215 , F02D13/0234 , F02D13/0265 , F02D13/0269 , F02D15/04 , F02D19/0605 , F02D19/0649 , F02D19/0665 , F02D19/081 , F02D35/023 , F02D35/028 , F02D41/0025 , F02D41/0087 , F02D41/3029 , F02D41/3035 , F02D41/3041 , F02D41/3076 , F02D41/38 , F02D2013/0292 , F02M26/01 , F02M26/04 , F02M26/07 , F02M26/08 , F02M26/23 , F02M26/28 , F02M26/33 , F02M26/43 , F02M31/02 , F02M31/20 , F02P19/00 , Y02T10/12 , Y02T10/125 , Y02T10/126 , Y02T10/128 , Y02T10/142 , Y02T10/36 , Y02T10/42
摘要： A premixed charge compression ignition engine, and a control system, is provided which effectively initiates combustion by compression ignition and maintains stable combustion while achieving extremely low nitrous oxide emissions, good overall efficiency and acceptable combustion noise and cylinder pressures. The present engine and control system effectively controls the combustion history, that is, the time at which combustion occurs, the rate of combustion, the duration of combustion and/or the completeness of combustion, by controlling the operation of certain control variables providing temperature control, pressure control, control of the mixture's autoignition properties and equivalence ratio control. The combustion control system provides active feedback control of the combustion event and includes a sensor, e.g. pressure sensor, for detecting an engine operating condition indicative of the combustion history, e.g. the start of combustion, and generating an associated engine operating condition signal. A processor receives the signal and generates control signals based on the engine operating condition signal for controlling various engine components to control the temperature, pressure, equivalence ratio and/or autoignition properties so as to variably control the combustion history of future combustion events to achieve stable, low emission combustion in each cylinder and combustion balancing between the cylinders.
摘要翻译：提供了预混合充气压缩点火发动机和控制系统，其通过压缩点火有效启动燃烧，并保持稳定的燃烧，同时实现极低的一氧化二氮排放，良好的总体效率和可接受的燃烧噪声和气缸压力。本发动机和控制系统通过控制提供温度控制的某些控制变量的操作来有效地控制燃烧历史，即燃烧发生时间，燃烧速率，燃烧持续时间和/或燃烧完整性，压力控制，混合物自燃特性控制和当量比控制。燃烧控制系统提供对燃烧事件的主动反馈控制，并且包括传感器，例如。压力传感器，用于检测指示燃烧历史的发动机运行状态，例如，燃烧开始，并产生相关联的发动机运转状态信号。处理器接收信号并基于发动机运转状态信号产生控制信号，以控制各种发动机部件，以控制温度，压力，当量比和/或自燃特性，以便可变地控制未来燃烧事件的燃烧历史以达到稳定，每个气缸中的低排放燃烧和气缸之间的燃烧平衡。

9. 发明授权

US4218455A 1-(4-Fluorophenyl)-4-[1,2,3,6-tetrahydro -4-(phenylthio)-1-pyridinyl]-butanones and related sulfoxides and sulfones 失效
标题翻译： 1-（4-氟苯基）-4- [1,2,3,6-四氢-4-（苯硫基）-1-吡啶基] - 丁酮和相关的亚砜和砜
公开(公告)号：US4218455A
公开(公告)日：1980-08-19
申请号：US922511
申请日：1978-07-10
申请人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
发明人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
IPC分类号： C07D211/72 , C07D213/70 , A61K31/44 , C07D213/04
CPC分类号： C07D213/70 , C07D211/72
摘要： Tetrahydropyridylbutyrophenones of the following formula IX: ##STR1## wherein x is hydrogen, halogen such as fluorine, chlorine, bromine or iodine, trifluoromethyl, alkoxy, nitro, cyano, amino, lower alkyl of 1 to 6 carbons, aryl or substituted aryl; y is hydrogen or halogen; and n is 0, 1 or 2; and the non-toxic, pharmaceutically acceptable acid addition salts thereof. Tetrahydropyridylbutanols having the formula X: ##STR2## wherein x and y are as defined above, as well as their non-toxic, pharmaceutically acceptable acid addition salts, are also disclosed. The compounds of the invention having the formulas IX and X are useful as antipsychotics.
摘要翻译：下式IX的四氢吡啶基丁酰苯：IX其中x是氢，卤素如氟，氯，溴或碘，三氟甲基，烷氧基，硝基，氰基，氨基，1至6个碳的低级烷基，芳基或取代的芳基; y是氢或卤素; 且n为0,1或2; 和其无毒的药学上可接受的酸加成盐。还公开了具有式X的XRD的四氢吡啶基丁醇，其中x和y如上所定义，以及它们的无毒的药学上可接受的酸加成盐。具有式IX和X的本发明化合物可用作抗精神病药。

10. 发明授权

US4134982A Antipsychotic 1-[4,4-Bis(4-fluorophenyl) butyl]-4-phenoxy-1,2,3,6-tetrahydropyridines 失效
标题翻译：抗真菌剂1-（4,4-BIS（4-氟苯基）丁基）-4-苯氧基-1,2,3,6-四氢吡啶
公开(公告)号：US4134982A
公开(公告)日：1979-01-16
申请号：US836867
申请日：1977-09-26
申请人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
发明人： Lawrence D. Wise , Patrick F. Flynn , Glenn C. Morrison
IPC分类号： A61K31/4425 , A61K31/445 , A61P25/00 , C07D211/46 , C07D211/74 , C07D211/94 , C07D213/68 , A61K31/44 , C07D213/69
CPC分类号： C07D211/74 , C07D211/46 , C07D213/68
摘要： 1-[4,4-Bis(4-fluorophenyl)butyl]-4-phenoxy-1,2,3,6-tetrahydropyridines and related piperidines are disclosed in the present invention. These compounds have the structural formulas: ##STR1## in which X is hydrogen, halogen, dihalogen, trifluoromethyl, lower alkoxy, nitro, amino, cyano, lower alkyl, aryl or substituted aryl. Also included are the corresponding non-toxic, pharmaceutically acceptable acid addition salts, and the N-oxides of compounds of the formulas I and II.The above compounds are useful in the management of manifestations of psychotic disorders.

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