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    • 5. 发明申请
    • SEAL FOR A PREFILLED MEDICAL JET INJECTION DEVICE
    • 密封用于医用喷射注射装置
    • WO2007088112A1
    • 2007-08-09
    • PCT/EP2007/050548
    • 2007-01-19
    • NOVO NORDISK A/SPOULSEN, Jens Ulrik
    • POULSEN, Jens Ulrik
    • A61M5/30A61M5/315A61M5/50
    • A61M5/30A61M2005/3103A61M2005/3106A61M2005/3118A61M2005/312A61M2005/31516
    • A sealing membrane 20 on a nozzle 10 for a jet injection device is adapted to seal off the nozzle orifice 12 by having a sealing rim 22 surrounding the nozzle orifice 12, which ensures a distinct closure of the nozzle orifice 12 to protect the nozzle geometry against damage and dirt and to protect the drug 30 contained in the cartridge 10 against contamination. The sealing rim 22 can narrowly enclose the nozzle orifice 12, or in case an adhesive 14 is applied to the nozzle face to ensure skin retention during injection, the sealing rim 22 can run in the middle of the adhesive covered area or entirely outside the adhesive covered area to protect the adhesive as well. A third sealing member 23 can also be provided to give a third distinct closure assurance in case the primary and secondary sealing membrane 20 is damaged. The third sealing member 23 can be one or more plug(s) adapted to press fit inside the nozzle orifice.
    • 用于喷射装置的喷嘴10上的密封膜20适于通过具有围绕喷嘴孔12的密封边缘22来密封喷嘴孔12,密封边缘22确保喷嘴孔12的明显封闭以保护喷嘴几何形状免受 损坏和污垢并且保护容纳在盒10中的药物30免受污染。 密封边缘22可以狭窄地包围喷嘴孔12,或者在将粘合剂14施加到喷嘴面以确保注射期间的皮肤保持的情况下,密封边缘22可以在粘合剂覆盖区域的中间或完全在粘合剂的外侧延伸 覆盖区域也保护粘合剂。 也可以提供第三密封构件23,以在初级和次级密封膜20损坏的情况下提供第三种不同的封闭保证。 第三密封构件23可以是适于压配合在喷嘴孔内的一个或多个塞子。
    • 8. 发明申请
    • DOSE SETTING DEVICE
    • 剂量设定装置
    • WO1998001168A2
    • 1998-01-15
    • PCT/DK1997000253
    • 1997-06-09
    • NOVO NORDISK A/SPOULSEN, Jens, UlrikLJUNGGREEN, HenrikCHRISTENSEN, Lars, Hofmann
    • NOVO NORDISK A/S
    • A61M00/00
    • A61M5/20A61M5/14546A61M5/14566A61M5/31525A61M5/31546A61M2005/31588A61M2205/581G06F19/00Y10S128/01
    • In a drug delivery device a dose to be apportioned from a cartridge is set by changing the relative position of co-operating dose setting elements (3, 5) and is injected by pressing a button (5) until this button abuts a stop (6). By operation of count up (7) or count down (8) buttons the dose is set and read into an electronic circuit (9) comprising a microprocessor and the dose setting movement of the dose setting elements relative to each other is performed by a motor (11) controlled by the circuit in accordance with the read in dose. The set dose is shown on a display (10). The motor (11) is further controlled to perform certain movements of the piston rod (3) so as retraction of this rod when a cartridge (1) is going to be changed an advancing of the piston rod to abutment with the piston (2) after the cartridge has been changed and further to advance this piston to expel air from the cartridge.
    • 在药物输送装置中,通过改变配合剂量设定元件(3,5)的相对位置来设定从药筒分配的剂量,并且通过按压按钮(5)来注射直到该按钮抵靠止动件(6) )。 通过计数(7)或倒计时(8)按钮的操作,剂量被设置并读入包括微处理器的电子电路(9),并且剂量设定元件相对于彼此的剂量设定运动由电动机 (11)由电路按照读取剂量控制。 设定的剂量显示在显示器(10)上。 电动机(11)被进一步控制以执行活塞杆(3)的某些运动,以便当筒(1)将改变活塞杆的前进以与活塞(2)邻接时,该杆的缩回, 在盒被改变之后,并且进一步推进该活塞以从盒中排出空气。