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1. 发明申请

US20200330616A1 BIOMIMETIC NON-IMMUNOGENIC NANOASSEMBLY FOR THE ANTITUMOR THERAPY 审中-公开
公开(公告)号：US20200330616A1
公开(公告)日：2020-10-22
申请号：US16763349
申请日：2018-10-30
申请人： POLITECNICO Dl TORINO
发明人： Valentina Alice CAUDA , Giancarlo CANAVESE , Tania LIMONGI , Nadia GARINO , Marco LAURENTI , Luisa RACCA , Andrea ANCONA , Marta CANTA , Bianca DUMONTEL
IPC分类号： A61K49/00 , A61K47/69 , A61K47/68
摘要： Nanoassembly (1) for inducing apoptosis in cancer cells comprising: a core (2) comprising at least a nanoparticle of a nano structured and semiconductor metal oxide, said nanoparticle being monocrystalline or polycrystalline; a shell (3) formed by a double phospholipid layer and proteins derived from an extracellular biovesicole chosen between an exosome, an ectosome, a connectosome, an oncosome and an apoptotic body, and an oncosome, said core (2) being enclosed inside said shell (3); and a plurality of targeting molecules (4, 4′, 4″) of said cancer cells, preferably monoclonal antibodies (4, 4′, 4″), said molecules (4, 4′, 4″) being anchored to the external surface of said biovesicole.

2. 发明申请

WO2013046239A1 MULTI-LOBED ANNULAR SEAL FOR PNEUMATIC AND HYDRAULIC APPLICATIONS AND SEALING UNIT EQUIPPED WITH SUCH SEAL 审中-公开
标题翻译：用于气动和液压应用的多孔密封和密封装置
公开(公告)号：WO2013046239A1
公开(公告)日：2013-04-04
申请号：PCT/IT2011/000339
申请日：2011-09-30
申请人： POLITECNICO Dl TORINO , FUNDACION TEKNIKER , CONTE Marcello , BELFORTE Guido , MAZZA Luigi
发明人： CONTE Marcello , BELFORTE Guido , MAZZA Luigi
IPC分类号： F16J15/32
CPC分类号： F16J15/3232
摘要： An annular seal (1) is described, made of polymeric material for pneumatic and hydraulic applications adapted to be operatively placed into an annular seat (12,35), and having a cross-section shaped as a first rounded part with slanted flanks and equipped, in a second part opposite to the first part, with at least three rounded sealing projections, or lobes (3,5,7).
摘要翻译：描述了环形密封件（1），其由用于气动和液压应用的聚合物材料制成，适用于可操作地放置在环形座（12,35）中，并且具有成形为第一圆形部分的横截面，其具有倾斜的侧面并配备在与第一部分相对的第二部分中具有至少三个圆形密封突起或凸角（3,5,7）。

3. 发明申请

WO2015008308A3 SYSTEM AND PROCESS FOR MEASURING AND EVALUATING AIR AND INERTIAL DATA 审中-公开
标题翻译：用于测量和评估空气和动态数据的系统和过程
公开(公告)号：WO2015008308A3
公开(公告)日：2015-06-11
申请号：PCT/IT2014000180
申请日：2014-07-08
申请人： POLITECNICO DL TORINO
发明人： GILI PIERO , BATTIPEDE MANUELA , LERRO ANGELA
IPC分类号： G01P13/02
CPC分类号： G01P13/025
摘要： A system (10) and a process are described, for measuring and evaluating air and inertial data of an aircraft (1) for indirectly estimating at least one incidence angle a and one skidding angle β with respect to a relative wind direction Wn of such aircraft (1).
摘要翻译：描述了一种用于测量和评估飞行器（1）的空气和惯性数据的系统（10）和过程，用于相对于这种飞行器的相对风向Wn间接地估计至少一个入射角a和一个滑动角β （1）。

4. 发明申请

WO2018211539A1 OPTICAL SENSOR, PROCESS FOR MAKING SUCH SENSOR AND EVALUATION SYSTEM COMPRISING AT LEAST ONE OF SUCH SENSORS 审中-公开
公开(公告)号：WO2018211539A1
公开(公告)日：2018-11-22
申请号：PCT/IT2018/000059
申请日：2018-04-24
申请人： POLITECNICO Dl TORINO
发明人： SALVO Milena , SANGERMANO, Marco , MARRO, Bellot Cristian , OLIVERO Massimo
IPC分类号： G01N21/552 , G01M11/08 , G01N21/77 , G01N21/84
摘要： An optical sensor (1) is described, comprising: an operating portion (3) aimed to be integrated, incorporated or immersed in at least one matrix (2) composed of one or more polymeric materials and/or composites thereof to optically guide an incoming optical signal (L I ) and an outgoing optical signal (L O ), the operating portion (3) comprising a portion (4) for entering the incoming optical signal (L I ) and/or for exiting the outgoing optical signal (L O ); a sensitive section made of optical fiber core (5) externally placed in direct contact with the matrix (2); an optically reflecting terminal section (7) placed in direct contact with the matrix (2), the terminal section (7) being adapted to optically reflect the incoming optical signal (L I ) to transform it into the outgoing optical signal (L O ); and a protecting covering section (9) of the optical fiber. A process for making of such optical sensor (1) and an evaluation system comprising at least one of such optical sensors (1) are also described.

5. 发明申请

WO2015145476A1 DEFORMABLE ACTUATING DEVICE WITH COAXIAL CONFIGURATION 审中-公开
标题翻译：具有同轴配置的可变形启动装置
公开(公告)号：WO2015145476A1
公开(公告)日：2015-10-01
申请号：PCT/IT2015/000077
申请日：2015-03-24
申请人： POLITECNICO Dl TORINO , FONDAZIONE ISTITUTO ITALIANO Dl TECNOLOGIA
发明人： FRENI Pierluigi , STOPPA Matteo
IPC分类号： H01L41/083 , H01L41/087 , H01L41/09 , H01L41/193 , H02N2/02 , H02N2/06
CPC分类号： H02N2/065 , H01L41/0836 , H01L41/193
摘要： A deformable actuating device (1) with coaxial configuration is described, comprising: at least one structure (3) with concentric layers coaxial with respect to at least one longitudinal axis (A- A) composed of an at least partial alternated overlapping with at least two electro-active concentric layers (3a) coaxial with said longitudinal axis (A-A), and of at least three conductive concentric layers (3b) coaxial with said longitudinal axis (A-A); at least one controlling and managing system (5) adapted to supply each of such electro-active concentric layers (3a) with at least one different current/voltage value (V 1 , V 2 , V 3 , V 4 ,..., V n ), said current/voltage values (V 1 , V 2 , V 3 , V 4 ,..., V n being mutually independent.
摘要翻译：描述了具有同轴构造的可变形的致动装置（1），包括：至少一个具有相对于至少一个纵向轴线（A-A）同轴的层的结构（3），所述至少一个纵向轴线（A-A）至少部分交替重叠与所述纵向轴线（AA）同轴的两个电活动同心层（3a）以及与所述纵向轴线（AA）同轴的至少三个导电同心层（3b）; 至少一个控制和管理系统（5），适于将这些电活动同心层（3a）中的每一个提供至少一个不同的电流/电压值（V1，V2，V3，V4，...，Vn），所述电流/电压值（V1，V2，V3，V4，...，Vn相互独立）。

6. 发明申请

WO2015008308A2 SYSTEM AND PROCESS FOR MEASURING AND EVALUATING AIR AND INERTIAL DATA 审中-公开
标题翻译：用于测量和评估空气和动态数据的系统和过程
公开(公告)号：WO2015008308A2
公开(公告)日：2015-01-22
申请号：PCT/IT2014/000180
申请日：2014-07-08
申请人： POLITECNICO Dl TORINO
发明人： GILI, Piero , BATTIPEDE, Manuela , LERRO, Angela
CPC分类号： G01P13/025
摘要： A system (10) and a process are described, for measuring and evaluating air and inertial data of an aircraft (1) for indirectly estimating at least one incidence angle a and one skidding angle β with respect to a relative wind direction Wn of such aircraft (1).
摘要翻译：描述了用于测量和评估飞行器（1）的空气和惯性数据的系统（10）和过程，用于间接估计至少一个入射角a和一个打滑角度＆bgr; 相对于这种飞机（1）的相对风向Wn。

7. 发明申请

WO2013061351A1 AERODYNAMIC PROFILE WITH VARIABLE TWIST AND PITCH 审中-公开
标题翻译：具有变化的TWIST和PITCH的航空配置文件
公开(公告)号：WO2013061351A1
公开(公告)日：2013-05-02
申请号：PCT/IT2012/000326
申请日：2012-10-24
申请人： POLITECNICO Dl TORINO
发明人： GIL, Piero , FRULLA, Giacomo
IPC分类号： B64C3/52
CPC分类号： B64C3/52 , Y02T50/14
摘要： An aerodynamic profile is described, comprising at least one portion of aerodynamic profile (1) composed of at least one first supporting profile (3a) and at least one second supporting profile (3b) adapted to support at least one layer of coating material of such portion of aerodynamic profile (1), such portion of aerodynamic profile (1) further comprising at least first actuating means (5) adapted to cooperate with at least one of such supporting profiles (3a) or (3b) to modify IΔΘ [ a value of incidence |θ| of such profile with respect to the other supporting profile around at least one rotation axis (R-R) parallel with an opening (A) of such portion of aerodynamic profile (1).
摘要翻译：描述了空气动力学轮廓，其包括由至少一个第一支撑轮廓（3a）和至少一个第二支撑轮廓（3b）组成的空气动力学轮廓（1）的至少一部分，所述至少一个第二支撑轮廓（3b）适于支撑至少一层这样的涂层材料空气动力学轮廓（1）的部分，空气动力学轮廓（1）的这一部分还包括至少第一致动装置（5），其适于与所述支撑轮廓（3a）或（3b）中的至少一个配合以修改IDelta Theta 的|θ| 相对于与空气动力学轮廓（1）的这种部分的开口（A）平行的至少一个旋转轴线（R-R）的另一个支撑轮廓具有这种轮廓。

8. 发明申请

WO2018073847A1 WEARABLE DEVICE FOR ACQUIRING ELECTROCARDIOGRAPHIC SIGNALS (ECG) SIGNALS 审中-公开
标题翻译：用于获取心电信号（ECG）信号的可佩戴装置
公开(公告)号：WO2018073847A1
公开(公告)日：2018-04-26
申请号：PCT/IT2017/000227
申请日：2017-10-17
申请人： POLITECNICO Dl TORINO
发明人： PASERO, Eros , CAFFARELLI , Federico
IPC分类号： A61B5/0404 , A61B5/0408 , A61B5/0428
CPC分类号： A61B5/681 , A61B5/0002 , A61B5/0404 , A61B5/04085 , A61B5/0428 , A61B5/7214 , A61B5/7225 , A61B5/725 , A61B2560/0214 , A61B2560/0468
摘要： A wearable device (10) for acquiring electrocardiographic (ECG) signals is described, which comprises an envelope (11) comprising a first electrode (14) arranged on a first surface (15) and a second electrode (16) arranged on a second surface (18), the first electrode (14) to be placed in contact with the skin of a subject to be monitored and the second electrode (16) being accessible to be placed in contact with the skin of another part of the subject different from the part in contact with the first electrode (14), the device (10) comprising an electronic circuit (20) with a supplying section (30), an analogue section (40) connected to the first electrode (14) and to the second electrode (16) and adapted to filter the signal acquired by the first electrode (14) and by the second electrode (16), and a digital section (50) connected to the analogue section (40) and adapted to acquire the output signal from the analogue section (40).
摘要翻译：描述了一种用于采集心电图（ECG）信号的可穿戴设备（10），其包括包封（11），该包封（11）包括布置在第一表面（15）上的第一电极（14）和第二电极（18）上的第一电极（16），所述第一电极（14）被放置成与待监测对象的皮肤接触，并且所述第二电极（16）可被接触以放置成与（10）包括具有供电部分（30）的电子电路（20），与第一电极（14）连接的模拟部分（14）和第二电极（16）并且适于对由第一电极（14）和第二电极（16）获取的信号进行滤波，以及连接到模拟部分（40）的数字部分（50）和适用于获取来自模拟部分（40）的输出信号。

9. 发明申请

WO2015015523A1 SELF-POWERED MOUSE EQUIPPED WITH MAGNETIC-MECHANICAL HARVESTER DEVICE FOR GENERATING ELECTRICITY 审中-公开
标题翻译：具有用于产生电力的磁力机械捕获器装置的自供电鼠标
公开(公告)号：WO2015015523A1
公开(公告)日：2015-02-05
申请号：PCT/IT2014/000195
申请日：2014-07-25
申请人： POLITECNICO Dl TORINO
发明人： BONISOLI ELVIO , Dl MONACO FRANCESCO , MANCA NICOLO' , MARCUCCIO GABRIELE , REPETTO MAURIZIO , TORNINCASA STEFANO
IPC分类号： G06F3/033 , H02K35/02
CPC分类号： H02K35/02 , G06F3/03543
摘要： A mouse (1) is described, comprising at least one magnetic-mechanical harvester device (2) for generating electric current supplying such mouse (1), such harvester device (2) comprising at least one mobile magnetic element (4) axially sliding along at least one translation axis A-A coaxial with at least one sliding guide (6); force optimizing elements (8) arranged in the side ends of such sliding guide (6) adapted to exert at least one force having an elastic and/or mechanical nature onto such mobile magnetic element (4), enabling a sliding of such mobile magnetic element (4) along such sliding guide (6); at least one first spiral-type winding (16), made of electrically conductive material, adapted to concatenate a magnetic flux created by such mobile magnet (4) and to develop an induced electromotive force when such flux changes in time due to the movement of such mobile magnetic element (4) along such sliding guide (6).
摘要翻译：描述了一种鼠标（1），其包括用于产生供应这种鼠标（1）的电流的至少一个磁 - 机械收集器装置（2），这种收割装置（2）包括至少一个沿轴向滑动的移动磁性元件（4）与至少一个滑动引导件（6）同轴的至少一个平移轴AA; 布置在这种滑动导向件（6）的侧端中的力优化元件（8）适于将至少一个具有弹性和/或机械性质的力施加到这种移动磁性元件（4）上，使得这种移动磁性元件（4）沿着所述滑动导向件（6）移动; 由导电材料制成的至少一个第一螺旋型绕组（16），其适于连接由这种可移动磁体（4）产生的磁通量，并且当这种磁通量随时间的变化而产生感应电动势时这种移动磁性元件（4）沿着这种滑动导向件（6）。

10. 发明申请

WO2014041573A1 AUTOMATIC MEASURING DEVICE, MEASURING PROCESS THROUGH SUCH DEVICE AND SYSTEM EQUIPPED WITH SUCH DEVICE 审中-公开
标题翻译：自动测量装置，通过这种装置的测量过程和装备有这些装置的系统
公开(公告)号：WO2014041573A1
公开(公告)日：2014-03-20
申请号：PCT/IT2013/000238
申请日：2013-09-10
申请人： POLITECNICO Dl TORINO , FONDAZIONE ISTITUTO ITALIANO Dl TECNOLOGIA (II)
发明人： RICCIARDI, Carlo , FERRANTE, Ivan , MURA, Andrea , CANAVESE, Giancarlo
IPC分类号： G01N9/00 , G01N5/02 , G01N29/02 , G01N29/036
CPC分类号： G01N9/002 , G01N5/02 , G01N29/022 , G01N29/036 , G01N2291/02809
摘要： An automatic measuring device (1) is described, comprising at least one measuring chamber (3) having therein at least one measuring volume (V) containing therein at least one cantilever sensor (5) for analysing at least one sampling fluid inserted inside such volume (V); at least one projecting means (7) of at least one laser light beam (9) incident onto such cantilever sensor (5), such chamber (3) being equipped with at least one window (11) transparent to such laser light beam (9); inserting and withdrawing means of such at least one sampling fluid into and from such volume (V) of such chamber (3). A system equipped with such device (1) and a measuring process through such device (1) are further described.
摘要翻译：描述了自动测量装置（1），其包括至少一个测量室（3），其中在其中容纳有至少一个测量体积（V），其中容纳有至少一个悬臂传感器（5），用于分析插入该容积内的至少一个采样流体（V）; 入射到这种悬臂传感器（5）上的至少一个激光束（9）的至少一个突出装置（7），这样的室（3）装备有至少一个对这种激光束（9）透明的窗口）; 将这样的至少一个取样流体的装置插入和取出到这种室（3）的这种容积（V）中。进一步描述配备有这种装置（1）的系统和通过这种装置（1）的测量过程。

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