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1. 发明申请

WO2009021577A2 EMBOLISIEREINRICHTUNG 审中-公开
公开(公告)号：WO2009021577A2
公开(公告)日：2009-02-19
申请号：PCT/EP2008/005119
申请日：2008-06-25
申请人： PFM PRODUKTE FÜR DIE MEDIZIN AKTIENGESELLSCHAFT , FREUDENTHAL, Franz
发明人： FREUDENTHAL, Franz
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/00477 , A61B2017/00867 , A61B2017/12054
摘要： Bei einer Embolisiereinrichtung (1) mit einem Grundkörper (3) und mit zumindest einer thrombogenen Faser (2), wobei der Grundkörper aus einer langgestreckten Primärform in eine Sekundärform überführbar ist, ist die zumindest eine thrombogene Faser (2) um den Grundkörper herumgewickelt an diesem angeordnet. Bei einem Verfahren zum Herstellen einer solchen Embolisierspirale wird eine einen Grundkörper (3) der Embolisierspirale (1) bildende Primärspirale (30) mit zumindest einer thrombogenen Faser (2) umwickelt und die Primärspirale (30) in eine Sekundärspirale umgeformt.
摘要翻译：在包括基体（3）和至少一个血栓形成纤维（2）的栓塞装置（1）中，基体从细长的主要形状变为次要形状。所述至少一种血栓形成纤维（2）缠绕在基体上并沿其布置。在用于制造这种栓塞的方法是一个初学者＆OUML;主体（3）的栓塞线圈的（1）形成的Prim＆AUML; rspirale（30）包裹着至少一个形成血栓的纤维（2）和在二次＆AUML主BEAR rspirale（30）; 螺旋形成。

2. 发明申请

WO2005013860A2 IMPLANTABLE DEVICE AS ORGAN VALVE REPLACEMENT 审中-公开
标题翻译：可植入器械作为器官瓣膜置换
公开(公告)号：WO2005013860A2
公开(公告)日：2005-02-17
申请号：PCT/EP2004/008368
申请日：2004-07-27
申请人： PFM PRODUKTE FÜR DIE MEDIZIN AKTIENGESELLSCHAFT , LÊ, Trong-Phi , JUNG, Johannes
发明人： LÊ, Trong-Phi , JUNG, Johannes
IPC分类号： A61F2/44
CPC分类号： A61F2/2418 , A61F2/2436 , A61F2/848 , A61F2220/005 , A61F2220/0058 , A61F2230/0078 , A61F2250/0039
摘要： An implantable device (1) for use in a human and/or animal body for replacement of an organ valve, has an elongate main body (10) having a first end and a second end (11,12) provided with openings, and a membrane element (20) provided with at least one opening, said device (1) having in a first operating state (primary form) a large ratio of length to transverse extent along an axis, and in a second operating state (secondary form) a smaller ratio of length to transverse extent along an axis, said device being reversibly convertible from the secondary form into the primary form by application of force against elastic material forces, wherein at least one of the two ends (11,12) of the main body (10) has an outwardly protruding anchoring portion (13,14) for anchoring the device (1) in the organ and/or a vessel. The invention refers also to a method for producing such implantable device (1).
摘要翻译：一种用于人体和/或动物体中用于置换器官瓣膜的可植入装置（1），具有细长的主体（10），所述细长的主体（10）具有第一端和第二端（11,12）所述装置（1）在第一操作状态（主要形式）中具有沿着轴线的大的长度与横向范围的比率，并且在第一操作状态（主要形式）中具有开口第二操作状态（第二形式）沿着轴线具有较小的长度与横向范围的比率，所述装置通过抵抗弹性材料力的作用力从第二形式可逆地转换为第一形式，其中两个端部中的至少一个（（10）的外表面（11,12）具有用于将所述装置（1）锚定在所述器官和/或器皿中的向外突出的锚定部分（13,14）。本发明还涉及用于制造这种可植入装置（1）的方法。

3. 发明申请

WO2004064671A2 IMPLANTIERBARE EINRICHTUNG 审中-公开
标题翻译：可植入设备
公开(公告)号：WO2004064671A2
公开(公告)日：2004-08-05
申请号：PCT/EP2004/000451
申请日：2004-01-21
申请人： PFM PRODUKTE FÜR DIE MEDIZIN AKTIENGESELLSCHAFT , FREUDENTHAL, Franz
发明人： FREUDENTHAL, Franz
IPC分类号： A61F
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12027 , A61B17/12031 , A61B17/12036 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B17/221 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867 , A61F2/01 , A61F2/88 , A61F2002/30093 , A61F2210/0019
摘要： Bei einer implantierbaren Einrichtung (1) zur Verwendung im menschlichen und/oder tierischen Körper zum Verschluss oder Teilverschluss von Defektöffnungen, Hohlräumen, Organwegen etc. oder zum Schaffen einer definierten Verbindungsöffnung zwischen Wandungen, Organen, Hohlräumen etc., mit einer Tragstruktur, die in einem ersten Betriebszustand (Primärform) ein grosses Verhältnis von Länge zu Querausdehnung entlang einer Achse (63) und in einem zweiten Betriebszustand (Sekundärform) ein kleineres Verhältnis von Länge zu Querausdehnung entlang der Achse (63) aufweist, wobei die Tragstruktur einen proximalen (20) und einen distalen Abschnitt (30) aufweist, ist die Tragstruktur aus einem einzigen drahtartigen Element (10) durch verschränkendes Wickeln und/oder Verwinden und/oder Verflechten nach Art eines Gewebes und/oder Geleges und/oder Netzes geformt. Bei einem Platziersystem insbesondere für eine solche implantierbare Einrichtung sind ein Vorschubelement (5), ein Führungsdraht (6,9) und/oder Innenmandrin und zumindest ein Haltedraht (80,81) vorgesehen, wobei der Führungsdraht (6) und der zumindest eine Haltedraht (80,81) zum Zusammenwirken mit einem proximalen Ende der implantierbaren Einrichtung (1) dienen, wobei die implantierbare Einrichtung (1) durch Relativbewegung von Haltedraht (80,81) und Führungsdraht (6) zu dem Vorschubelement (5) aus einer Primärform in eine Sekundärform und umgekehrt überführbar ist.
摘要翻译：
在用于人类和/或动物K＆ouml使用的可植入装置（1）;开口，Hohlr BEAR;体为闭合或缺陷＆OUML umen，器官通道等的局部封闭，或用于提供定义的连接＆OUML;开口大Verh＆AUML;壁，器官，Hohlr TREES等，具有支撑结构，该结构在第一运行状态（rform的Prim＆AUML）;之间ltnis L＆AUML;长度以横向范围沿一轴线（63）和在第二操作条件（二次＆AUML; rform）较小Verh＆AUML; ltnis L＆AUML;具有沿所述轴线（63）的长度以横向范围，所述具有近端（20）和远端部分（30），所述支撑结构（单丝状元件10的）的支撑结构坚持以织物和/或稀松布和/或网状的方式成形的缠绕和/或扭曲和/或编织。在定位系统中，特别是用于导航使用R，使得可植入装置是一个馈电元件（5），A F导航使用导丝（6,9）和/或内心轴和至少一个保持电线（80,81），其中R导航使用导丝（6）和用于与植入装置（1）的近端配合，所述至少一个支撑线（80,81）被使用，其特征在于，所述可植入装置（1）由保持线的相对运动（80,81）和F导航使用导丝（6）馈电元件（5）从原始到次要，反之亦然。

4. 发明公开

EP2053976A2 IMPLANTIERBARE EINRICHTUNG 有权转让
标题翻译：可植入装置
公开(公告)号：EP2053976A2
公开(公告)日：2009-05-06
申请号：EP07818732.5
申请日：2007-10-05
申请人： PFM Produkte für die Medizin Aktiengesellschaft
发明人： FREUDENTHAL, Franz
IPC分类号： A61B17/00 , A61F2/06 , A61B19/00 , A61B17/12
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12031 , A61B17/12036 , A61B17/12109 , A61B17/12113 , A61B17/12118 , A61B17/12122 , A61B17/12172 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00615 , A61B2017/00628 , A61B2017/00867 , A61B2017/00893 , A61B2017/12054 , A61L31/08
摘要： In an implantable device (1) to be used in the human and/or animal body for occluding or partially occluding defect openings (2), hollow spaces, organ tracts, etc. or for creating a defined connecting opening between walls, organs, hollow spaces, etc., with a support structure (17) which has a great length-to-width ratio along an axis (x) in a primary shape and has a smaller length-to-width ratio along the axis (x) in a secondary shape, and wherein the support structure (17) has proximal and distal portions (10, 11) and is formed in the manner of a braid and/or tissue and/or scrim and/or net, at least the portion (11) in the secondary shape has a first subsidiary portion (14) facing outwards away from the other portion (10) or facing the latter and, in order to form at least a double ply, has a second subsidiary portion (13) first deploying from the primary shape to the secondary shape and folded back in the direction of the other portion (10) or inwards onto the first subsidiary portion (14).

5. 发明公开

EP1585445A2 IMPLANTIERBARE EINRICHTUNG 有权转让
公开(公告)号：EP1585445A2
公开(公告)日：2005-10-19
申请号：EP04703781.7
申请日：2004-01-21
申请人： PFM Produkte für die Medizin Aktiengesellschaft
发明人： FREUDENTHAL, Franz
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12027 , A61B17/12031 , A61B17/12036 , A61B17/12109 , A61B17/12172 , A61B17/12177 , A61B17/221 , A61B90/39 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00867 , A61F2/01 , A61F2/88 , A61F2002/30093 , A61F2210/0019
摘要： Disclosed is an implantable device (1) to be used in a human and/or animal body for occluding or partially occluding defective openings, hollow spaces, organ tracts, etc. or creating a defined connecting opening between walls, organs, hollow spaces, etc. Said implantable device (1) comprises a support structure which has a great length-to-width ratio along an axis (63) in a first operating state (primary shape) while having a smaller length-to-width ratio along said axis (63) in a second operating state (secondary shape). The support structure is provided with a proximal (20) and a distal section (30) and is formed from a single wire-type element (10) by intercoiling and/or intertwining and/or interweaving like a tissue and/or a cluster and/or a net. Also disclosed is a placing system especially for such an implantable device, comprising an advancing element (5), a directing wire (6,9) and/or an inner mandrin, and at least one holding wire (80,81). The directing wire (6) and the at least one holding wire (80,81) are used for cooperating with a proximal end of the implantable device (1), the implantable device (1) being transformable from a primary shape into a secondary shape and vice versa by moving the holding wire (80, 81) and the directing wire (6) relative to the advancing element (5).
摘要翻译：本发明公开了一种用于人体和/或动物体中的可植入装置（1），用于阻塞或部分阻塞有缺陷的开口，空腔，器官区等，或者在壁，器官，空腔等之间形成限定的连接开口所述可植入装置（1）包括支撑结构，所述支撑结构在第一操作状态（主要形状）下沿着轴线（63）具有大的长宽比，同时沿着所述轴线具有更小的长宽比 63）处于第二操作状态（第二形状）。支撑结构设置有近侧部分（20）和远侧部分（30）并且由单个线型元件（10）通过像组织和/或簇一样交织和/或缠结和/或交织而形成，并且 /或一个网。还公开了一种尤其用于这样的可植入装置的放置系统，其包括推进元件（5），引导线（6,9）和/或内部心轴，以及至少一个保持线（80,81）。引导线（6）和至少一根保持线（80,81）用于与可植入装置（1）的近端配合，可植入装置（1）可从主要形状变形为次要形状并且通过相对于推进元件（5）移动保持线（80,81）和引导线（6），反之亦然。

6. 发明公开

EP1539030A2 EXTRAKTIONSVORRICHTUNG 有权
标题翻译：提取装置
公开(公告)号：EP1539030A2
公开(公告)日：2005-06-15
申请号：EP03750525.2
申请日：2003-09-11
申请人： PFM Produkte für die Medizin Aktiengesellschaft
发明人： FREUDENTHAL, Franz , GÜNTHER, Rolf W. , SCHMITZ-RODE, Thomas
IPC分类号： A61F2/01 , A61B17/22
CPC分类号： A61B17/221 , A61B2017/2212 , A61B2017/2215 , A61F2/01
摘要： The invention relates to an extraction device (1) for extracting objects (2), especially thrombins, foreign bodies etc. from cavities (3) in a human or animal body, by means of a first and a second compressible and expandable catching box (10, 20, 102, 110), between which the object (2) can be arranged . The catching boxes can be displaced against each other and can be inserted into each other. In said device, at least one catching box (10), in an expanded state, is embodied in an umbrella-type manner and is provided with flexible wire-type adjusting elements for specific modifications of the shape and/or position of the catching box, such that the object can be caught in one catching box and drawn into the other catching box (20).

7. 发明授权

EP1113755B1 VORRICHTUNG ZUM ERGREIFEN VON KÖRPERN 有权
标题翻译：设备，用于取得机构
公开(公告)号：EP1113755B1
公开(公告)日：2003-12-17
申请号：EP99948780.4
申请日：1999-09-16
申请人： PFM Produkte für die Medizin Aktiengesellschaft
发明人： FREUDENTHAL, Franz
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/2212 , A61B2017/2215
摘要： The invention relates to a device for grasping bodies, objects or particles, especially foreign bodies, agglomerates, stones or other organic deposits or accumulations from human or animal vessels or body cavities, comprising a long proximal part (30) and a distal part (20) which is provided with a loop. The loop consists of a flexible and elastic material and is at least partially a double loop (21) which has a loop center. Starting from a primary configuration said double loop can form a secondary configuration by interacting with a long, tubular element (40) which at least partially surrounds the device. The loop is bent at a predetermined angle from the longitudinal axis to the long proximal part (30) at least in its primary configuration.

8. 发明公开

EP0888083A1 DEVICE FOR CLOSURE OF BODY DEFECT OPENINGS 失效
标题翻译：封闭装置用于修复身体缺陷开口
公开(公告)号：EP0888083A1
公开(公告)日：1999-01-07
申请号：EP97902322.0
申请日：1997-02-04
申请人： PFM Produkte für die Medizin Aktiengesellschaft
发明人： NEUSS, Malte , FREUDENTHAL, Franz
IPC分类号： A61B17
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619 , A61B2017/00623
摘要： The invention relates to a device for closure of defect openings in the human or animal body, which device, in a first state, can assume an elongate shape with a high ratio of length to transverse extent, and, in the implanted state, has a shape with a lower ration of length to transverse extent, the device being deformable in the radial direction and comprising first arrangements (8, 24, 31) with which the device, in the implanted state, supports itself elastically against the margin of the opening which is to be closed and thereby centres itself approximately within the opening, characterized in that the device comprises second arrangements (7, 9, 20, 21, 32) which, in the implanted state, bear with positive engagement on opposite sides of the tissue surrounding the opening which is to be closed.

9. 发明公开

EP2190359A2 EMBOLISIEREINRICHTUNG 有权转让
公开(公告)号：EP2190359A2
公开(公告)日：2010-06-02
申请号：EP08773627.8
申请日：2008-06-25
申请人： PFM Produkte für die Medizin Aktiengesellschaft
发明人： FREUDENTHAL, Franz
IPC分类号： A61B17/12
CPC分类号： A61B17/12022 , A61B17/12145 , A61B17/1215 , A61B17/12154 , A61B2017/00477 , A61B2017/00867 , A61B2017/12054
摘要： In an embolization device (1) with a main body (3) and with at least one thrombogenic fibre (2), which main body can be converted from an elongate primary shape to a secondary shape, the at least one thrombogenic fibre (2) is arranged in a configuration wound around the main body. In a method for producing an embolization coil of this kind, a primary coil (30) forming a main body (3) of the embolization coil (1) has at least one thrombogenic fibre (2) wound around it, and the primary coil (30) is converted in shape to a secondary coil.
摘要翻译：在具有主体（3）和至少一个血栓形成纤维（2）的栓塞装置（1）中，所述至少一个形成血栓的纤维（2）可以从细长主要形状转变为次要形状，以缠绕在主体周围的构造布置。在用于制造这种栓塞线圈的方法中，形成栓塞线圈（1）的主体（3）的初级线圈（30）具有缠绕在其上的至少一根血栓形成纤维（2），并且初级线圈 30）的形状被转换成次级线圈。

10. 发明授权

EP1246570B9 IMPLANT FOR THE CLOSING OF DEFECT OPENINGS IN THE BODY OF A HUMAN OR ANIMAL AND A SYSTEM FOR THE PLACEMENT OF SUCH AN IMPLANT 有权
标题翻译：植入插入此类植入人体或动物体设备故障，开口CLOSE
公开(公告)号：EP1246570B9
公开(公告)日：2008-11-05
申请号：EP01900383.9
申请日：2001-01-03
申请人： PFM Produkte für die Medizin Aktiengesellschaft
发明人： FREUDENTHAL, Franz , SIEGNER, Georg
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B2017/00575 , A61B2017/00592 , A61B2017/00597 , A61B2017/00606 , A61B2017/00619

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