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1. 发明申请

WO2008115497A2 SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING CHROMSOME COPY NUMBER 审中-公开
标题翻译：用于清除噪声遗传数据的系统和方法，并确定复杂的编号
公开(公告)号：WO2008115497A2
公开(公告)日：2008-09-25
申请号：PCT/US2008/003547
申请日：2008-03-17
申请人： GENE SECURITY NETWORK , RABINOWITZ, Matthew , SWEETKIND-SINGER, Josh , BANJEVIC, Milena , JOHNSON, David, Scott , KIJACIC, Dusan , PETROV, Dimitri , XU, Jing , DEMKO, Zachary, P.
发明人： RABINOWITZ, Matthew , SWEETKIND-SINGER, Josh , BANJEVIC, Milena , JOHNSON, David, Scott , KIJACIC, Dusan , PETROV, Dimitri , XU, Jing , DEMKO, Zachary, P.
IPC分类号： G06F19/00
CPC分类号： G06F19/22 , G06F19/18 , G06F19/20 , G06F19/24
摘要： Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Genetic material from the target individual is acquired, amplified and the genetic data is measured using known methods. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment of the invention, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment of the invention, the chromosome copy number can be determined from the measured genetic data of a single or small number of cells, with or without genetic information from one or both parents. In another embodiment of the invention, these determinations are made for the purpose of embryo selection in the context of in-vitro fertilization. In another embodiment of the invention, the genetic data can be reconstructed for the purposes of making phenotypic predictions.
摘要翻译：本文公开了一种系统和方法，用于增加测量的遗传数据的保真度，进行等位基因调用，并确定在一组或一组细胞中或从片段DNA中确定非整倍体的状态，其中有限数量的遗传数据是可用的获取，扩增来自目标个体的遗传物质，并使用已知方法测量遗传数据。使用目标基因组与遗传相关个体的基因组之间的预期相似性来重建差或不正确测量的碱基对，缺失的等位基因和缺失区域。根据本发明的一个实施方案，使用来自一个或两个亲本的二倍体细胞的较大样本的更完整的遗传数据，在多个基因座重建来自胚胎细胞的不完全遗传数据，具有或不具有来自一个的单倍体遗传数据或双亲。在本发明的另一个实施方案中，染色体拷贝数可以从单个或少数细胞的测量的遗传数据确定，具有或不具有来自一个或两个亲本的遗传信息。在本发明的另一个实施方案中，这些确定是为了在体外受精的背景下进行胚胎选择的目的。在本发明的另一个实施方案中，为了进行表型预测的目的，可以重建遗传数据。

2. 发明申请

WO2008115497A3 SYSTEM AND METHOD FOR CLEANING NOISY GENETIC DATA AND DETERMINING CHROMSOME COPY NUMBER 审中-公开
标题翻译：用于清除噪声遗传数据的系统和方法，并确定复杂的编号
公开(公告)号：WO2008115497A3
公开(公告)日：2009-05-28
申请号：PCT/US2008003547
申请日：2008-03-17
申请人： GENE SECURITY NETWORK , RABINOWITZ MATTHEW , SWEETKIND-SINGER JOSH , BANJEVIC MILENA , JOHNSON DAVID SCOTT , KIJACIC DUSAN , PETROV DIMITRI , XU JING , DEMKO ZACHARY P
发明人： RABINOWITZ MATTHEW , SWEETKIND-SINGER JOSH , BANJEVIC MILENA , JOHNSON DAVID SCOTT , KIJACIC DUSAN , PETROV DIMITRI , XU JING , DEMKO ZACHARY P
IPC分类号： G06F19/18 , G06F19/20 , G06F19/22 , G06F19/24
CPC分类号： G06F19/22 , G06F19/18 , G06F19/20 , G06F19/24
摘要： Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Genetic material from the target individual is acquired, amplified and the genetic data is measured using known methods. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment of the invention, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment of the invention, the chromosome copy number can be determined from the measured genetic data of a single or small number of cells, with or without genetic information from one or both parents. In another embodiment of the invention, these determinations are made for the purpose of embryo selection in the context of in-vitro fertilization. In another embodiment of the invention, the genetic data can be reconstructed for the purposes of making phenotypic predictions.
摘要翻译：本文公开了一种系统和方法，用于增加测量的遗传数据的保真度，进行等位基因调用，并确定在一组或一组细胞中或从片段DNA中确定非整倍体的状态，其中有限数量的遗传数据是可用的获取，扩增来自目标个体的遗传物质，并使用已知方法测量遗传数据。使用目标基因组与遗传相关个体的基因组之间的预期相似性来重建差或不正确测量的碱基对，缺失的等位基因和缺失区域。根据本发明的一个实施方案，使用来自一个或两个亲本的二倍体细胞的较大样本的更完整的遗传数据，在多个基因座重建来自胚胎细胞的不完全遗传数据，具有或不具有来自一个的单倍体遗传数据或双亲。在本发明的另一个实施方案中，染色体拷贝数可以从单个或少数细胞的测量的遗传数据确定，具有或不具有来自一个或两个亲本的遗传信息。在本发明的另一个实施方案中，这些确定是为了在体外受精的背景下进行胚胎选择的目的。在本发明的另一个实施方案中，为了进行表型预测的目的，可以重建遗传数据。

3. 发明专利

DE202020002613U1 Mehrzweckkarre 未知
公开(公告)号：DE202020002613U1
公开(公告)日：2020-07-06
申请号：DE202020002613
申请日：2020-06-16
申请人： PETROV DIMITRI
IPC分类号： B60R9/06 , B62B3/00
摘要： Mehrzweckkarre zum Transport von Gütern aller Art, bestehend aus mindestens einer Tragplattform (3), einer Radanordnung mit mindestens einem Tragrad (5.2) und mindestens einem Griffteil und/oder einer Griffstange (4.1), dadurch gekennzeichnet, dass im Tragrahmen (2) der erfindungsgemäßen Mehrzweckkarre mindestens ein Adapter und/oder eine Schnellspannvorrichtung mit Betätigungshebel (3.2) oder Vergleichbares zur heckseitigen, freitragenden Befestigung an einem Kraftfahrzeug integriert ist.

4. 发明专利

CA2484674C METHOD AND APPARATUS FOR LOCATING THE TRAJECTORY OF AN OBJECT IN MOTION 未知
公开(公告)号：CA2484674C
公开(公告)日：2013-04-02
申请号：CA2484674
申请日：2004-10-14
申请人： PETROV DIMITRI
发明人： PETROV DIMITRI
IPC分类号： G01S5/00 , A63B67/02 , A63B69/36
摘要： An object locating system detects the presence of an object as it passes through two consecutive planar fields of view. Two pairs of optical sensor arrays with multiple, directed, pixel detectors observe the object from two angles as the object passes through each consecutive field of view. The locations of penetrations of the respective fields of view are calculated by triangulation. Using this data, the known location of the take- off point and/or the delay between penetrations, the trajectory of the object in time and space is calculated. Applications include projecting the range of a driven golf ball, measuring the respective arriving and departing velocities of a hit baseball, and determining the trajectory and origin of an arriving projectile, as in the case of the threat to a military vehicle.

5. 发明专利

DE102009058401B4 Möbel 未知
公开(公告)号：DE102009058401B4
公开(公告)日：2012-11-22
申请号：DE102009058401
申请日：2009-12-15
申请人： PETROV DIMITRI
发明人： PETROV DIMITRI
IPC分类号： A47B45/00 , A47B46/00 , A47B57/00 , A47B88/00
摘要： Die Erfindung betrifft ein Möbel mit mehreren Behältern, die in wenigstens zwei übereinander liegenden Lagen angeordnet sind. Gemäß der Erfindung wird vorgeschlagen, dass zwischen den Lagen eine im Wesentlichen horizontal verlaufende Schiene angeordnet ist, auf der die Behälter einer Lage hin- und herbewegbar sind.

6. 发明专利

CA2626160A1 PIVOTING GUTTER MOUNTED ON HINGED BRACKETS EQUIPPED WITH A MAGNETIC LATCH 未知
公开(公告)号：CA2626160A1
公开(公告)日：2009-09-12
申请号：CA2626160
申请日：2008-03-12
申请人： PETROV DIMITRI
发明人： PETROV DIMITRI
IPC分类号： E04D13/064
摘要： The invention relates to means and methods for maintaining a rain gutter either in an upward, rain- gathering position or in a downward position under the eave, where it can be cleaned with a water jet, and in winter remains protected from sliding sn ow and ice. The gutter is supported by hinged brackets equipped with a magnetic latch th at is closed when the gutter is in the upward position. Transition from the upward to the downward position, or vice versa, is achieved from the ground by means of a hook attached to a pole.

7. 发明专利

CA2484674A1 METHOD AND APPARATUS FOR LOCATING THE TRAJECTORY OF A PROJECTILE 未知
公开(公告)号：CA2484674A1
公开(公告)日：2005-04-15
申请号：CA2484674
申请日：2004-10-14
申请人： PETROV DIMITRI
发明人： PETROV DIMITRI
IPC分类号： A63B67/02 , A63B69/36 , G01S5/00
摘要： An object locating system detects the presence of an object as it passes through two consecutive planar fields of view. Two pairs of optical sensor arrays with multiple, directed, pixel detectors observe the object from two angles as the object passes through each consecutive field of view. The locations of penetrations of the respective fields of view are calculated by triangulation. Using this data, the known location of the take - off point and/or the delay between penetrations, the trajectory of the object in time and spa ce is calculated. Applications include projecting the range of a driven golf ball, measuring t he respective arriving and departing velocities of a hit baseball, and determining the trajectory and origin of an arriving projectile, as in the case of the threat to a military vehicl e.

8. 发明专利

DE102009058401A1 Möbel 未知
公开(公告)号：DE102009058401A1
公开(公告)日：2011-06-16
申请号：DE102009058401
申请日：2009-12-15
申请人： PETROV DIMITRI
发明人： PETROV DIMITRI
IPC分类号： A47B45/00 , A47B46/00 , A47B57/00 , A47B88/00

9. 发明专利

CA2444464A1 METHOD AND APARATUS FOR LOCATING THE TRAJECTORY OF A PROJECTILE IN MOTION 未知
公开(公告)号：CA2444464A1
公开(公告)日：2005-04-15
申请号：CA2444464
申请日：2003-10-15
申请人： PETROV DIMITRI
发明人： PETROV DIMITRI
IPC分类号： A63B57/00 , A63B67/02 , F41H5/007 , G01C11/30 , G01S17/66
摘要： An object locating system detects the presence of an illuminated object as it passes through two consecutive planar fields of view. Pairs of optical senso r arrays with multiple, directed, pixel detectors observe the object from two angles as th e object passes through each consecutive field of view. The locations of penetrations of the respective fields of view are calculated by triangulation. Using the delay between penetrations, the trajectory of the object in time and space is calculated.

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