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1. 发明专利

JP2007534764A Antifungal drug delivery 审中-公开
公开(公告)号：JP2007534764A
公开(公告)日：2007-11-29
申请号：JP2007510881
申请日：2005-04-25
申请人：ニムニ、マーセルNIMNI, Marcel , パンディア、アナントPANDYA, Anant
发明人：ニムニ、マーセル , パンディア、アナント
IPC分类号： A61K31/137 , A61K9/00 , A61K47/10 , A61P17/00 , A61P31/10
CPC分类号： A61K31/343 , A61K9/0014 , A61K31/137 , A61K31/4174 , A61K31/496 , A61K45/06 , A61K47/10 , A61K2300/00
摘要：改善された皮膚および爪の局所的塗布用抗真菌組成物は、（１）アリルアミン抗真菌化合物と、（２）治療上有効濃度のアリルアミン抗真菌化合物が溶液で局所的に塗布され得る程度までアリルアミン抗真菌化合物が溶解する、芳香族置換基で置換された脂肪族アルコールと、（３）芳香族アルコールが溶解する低級脂肪族アルコールと、および（ｄ）水または水相溶性混合溶媒を含む。アリルアミン抗真菌化合物は、テルビナフィンまたはナフチフィンであり得る。芳香族置換基で置換された脂肪族アルコールは、ベンジルアルコールまたはフェネチルアルコールであり得る。低級脂肪族アルコールは、エチルアルコールまたはイソプロピルアルコールであり得る。代替例において、組成物はさらに、さらなる抗真菌化合物を含み得る。

2. 发明公开

EP1755575A4 ANTIFUNGAL DRUG DELIVERY 审中-公开
标题翻译：提供产品抗真菌剂
公开(公告)号：EP1755575A4
公开(公告)日：2010-09-22
申请号：EP05739804
申请日：2005-04-25
申请人： NIMNI MARCEL , PANDYA ANANT
发明人： NIMNI MARCEL , PANDYA ANANT
IPC分类号： A61K31/137 , A61K9/00 , A61K45/06 , A61K47/10
CPC分类号： A61K31/343 , A61K9/0014 , A61K31/137 , A61K31/4174 , A61K31/496 , A61K45/06 , A61K47/10 , A61K2300/00

3. 发明公开

EP1755575A2 ANTIFUNGAL DRUG DELIVERY 审中-公开
标题翻译：提供产品抗真菌剂
公开(公告)号：EP1755575A2
公开(公告)日：2007-02-28
申请号：EP05739804.2
申请日：2005-04-25
申请人： Nimni, Marcel , Pandya, Anant
发明人： Nimni, Marcel , Pandya, Anant
IPC分类号： A61K31/137 , A61K9/00 , A61K31/135 , A61K31/13
CPC分类号： A61K31/343 , A61K9/0014 , A61K31/137 , A61K31/4174 , A61K31/496 , A61K45/06 , A61K47/10 , A61K2300/00
摘要： An improved antifungal composition for topical application to the skin and nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent in which the allylamine antifungal compound is soluble to a degree that a therapeutically effective concentration of the allylamine antifungal compound can be applied topically in solution; (3) a lower aliphatic alcohol in which the aromatic alcohol is soluble; and (d) water or a water-compatible solvent mixture. The allylamine antifungal compound can be terbinafine or naftifine. The aliphatic alcohol substituted with an aromatic substituent can be benzyl alcohol or phenethyl alcohol. The lower aliphatic alcohol can be ethyl alcohol or isopropyl alcohol. In an alternative, the composition can further comprise an additional antifungal compound. Another aspect of the invention is a method for treatment of a fungal infection of skin or nails comprising administering the antifungal composition of the present invention topically to the skin or nails in an amount therapeutically effective to treat the fungal infection.

4. 发明专利

NO20065422L 未知
公开(公告)号：NO20065422L
公开(公告)日：2007-01-19
申请号：NO20065422
申请日：2006-11-24
申请人： PANDYA ANANT
发明人： NIMNI MARCEL , PANDYA ANANT
IPC分类号： A61K31/131 , A61K9/00 , A61K9/08 , A61K31/137 , A61P31/10
摘要： An improved antifungal composition for topical application to the skin and nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent in which the allylamine antifungal compound is soluble to a degree that a therapeutically effective concentration of the allylamine antifungal compound can be applied topically in solution; (3) a lower aliphatic alcohol in which the aromatic alcohol is soluble; and (d) water or a water-compatible solvent mixture. The allylamine antifungal compound can be terbinafine or naftifine. The aliphatic alcohol substituted with an aromatic substituent can be benzyl alcohol or phenethyl alcohol. The lower aliphatic alcohol can be ethyl alcohol or isopropyl alcohol. In an alternative, the composition can further comprise an additional antifungal compound. Another aspect of the invention is a method for treatment of a fungal infection of skin or nails comprising administering the antifungal composition of the present invention topically to the skin or nails in an amount therapeutically effective to treat the fungal infection.

5. 发明专利

CA405882A BUILDING ROOF 未知
公开(公告)号：CA405882A
公开(公告)日：1942-07-07
申请号：CA405882D
申请人： PANDYA ANANT HIRALAL
发明人： PANDYA ANANT HIRALAL

6. 发明专利

NO20065422A 未知
公开(公告)号：NO20065422A
公开(公告)日：2007-01-19
申请号：NO20065422
申请日：2006-11-24
申请人： PANDYA ANANT
发明人： NIMNI MARCEL , PANDYA ANANT
IPC分类号： A61K31/131 , A61K9/00 , A61K9/08 , A61K31/137 , A61P31/10
CPC分类号： A61K31/343 , A61K9/0014 , A61K31/137 , A61K31/4174 , A61K31/496 , A61K45/06 , A61K47/10 , A61K2300/00

7. 发明专利

BRPI0510286A 未知
公开(公告)号：BRPI0510286A
公开(公告)日：2007-10-30
申请号：BRPI0510286
申请日：2005-04-25
申请人： NIMNI MARCEL , PANDYA ANANT
发明人： NIMNI MARCEL , PANDYA ANANT
IPC分类号： A61K31/135 , A61K9/00 , A61K31/13 , A61K31/137
摘要： An improved antifungal composition for topical application to the skin and nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent in which the allylamine antifungal compound is soluble to a degree that a therapeutically effective concentration of the allylamine antifungal compound can be applied topically in solution; (3) a lower aliphatic alcohol in which the aromatic alcohol is soluble; and (d) water or a water-compatible solvent mixture. The allylamine antifungal compound can be terbinafine or naftifine. The aliphatic alcohol substituted with an aromatic substituent can be benzyl alcohol or phenethyl alcohol. The lower aliphatic alcohol can be ethyl alcohol or isopropyl alcohol. In an alternative, the composition can further comprise an additional antifungal compound. Another aspect of the invention is a method for treatment of a fungal infection of skin or nails comprising administering the antifungal composition of the present invention topically to the skin or nails in an amount therapeutically effective to treat the fungal infection.

8. 发明专利

CA2564134A1 ANTIFUNGAL DRUG DELIVERY 未知
公开(公告)号：CA2564134A1
公开(公告)日：2005-11-10
申请号：CA2564134
申请日：2005-04-25
申请人： NIMNI MARCEL , PANDYA ANANT
发明人： NIMNI MARCEL , PANDYA ANANT
IPC分类号： A61K31/135 , A61K9/00 , A61K31/13 , A61K31/137
摘要： An improved antifungal composition for topical application to the skin and nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent in which the allylamine antifungal compound is soluble to a degree that a therapeutically effective concentration of the allylamine antifungal compound can be applied topically in solution; (3) a lower aliphatic alcohol in which the aromatic alcohol is soluble; and (d) water or a water-compatible solvent mixture. The allylamine antifungal compound can be terbinafine or naftifine. The aliphatic alcohol substituted with an aromatic substituent can be benzyl alcohol or phenethyl alcohol. The lower aliphatic alcohol can be ethyl alcohol or isopropyl alcohol. In an alternative, the composition can further comprise an addition al antifungal compound. Another aspect of the invention is a method for treatme nt of a fungal infection of skin or nails comprising administering the antifung al composition of the present invention topically to the skin or nails in an amount therapeutically effective to treat the fungal infection.

9. 发明专利

AU2005237541A1 Antifungal drug delivery 未知
公开(公告)号：AU2005237541A1
公开(公告)日：2005-11-10
申请号：AU2005237541
申请日：2005-04-25
申请人： NIMNI MARCEL , PANDYA ANANT
发明人： NIMNI MARCEL , PANDYA ANANT
IPC分类号： A61K31/13 , A61K9/00 , A61K31/135 , A61K31/137
摘要： An improved antifungal composition for topical application to the skin and nails comprises: (1) an allylamine antifungal compound; (2) an aliphatic alcohol substituted with an aromatic substituent in which the allylamine antifungal compound is soluble to a degree that a therapeutically effective concentration of the allylamine antifungal compound can be applied topically in solution; (3) a lower aliphatic alcohol in which the aromatic alcohol is soluble; and (d) water or a water-compatible solvent mixture. The allylamine antifungal compound can be terbinafine or naftifine. The aliphatic alcohol substituted with an aromatic substituent can be benzyl alcohol or phenethyl alcohol. The lower aliphatic alcohol can be ethyl alcohol or isopropyl alcohol. In an alternative, the composition can further comprise an additional antifungal compound. Another aspect of the invention is a method for treatment of a fungal infection of skin or nails comprising administering the antifungal composition of the present invention topically to the skin or nails in an amount therapeutically effective to treat the fungal infection.

10. 发明申请

WO2006100489A2 A TRANSDERMAL TOPICAL COMPOSITION AND ITS USES 审中-公开
标题翻译：一种超导主题组合物及其用途
公开(公告)号：WO2006100489A2
公开(公告)日：2006-09-28
申请号：PCT/GB2006/001063
申请日：2006-03-22
申请人： TRANSPHASE LIMITED , PANDYA, Anant, K.
发明人： PANDYA, Anant, K.
IPC分类号： A61K9/00 , A61K9/12 , A61K47/24
CPC分类号： A61K9/0014 , A61K9/12 , A61K47/24
摘要： At least one silicone is used to modify the release profile of the active compound(s) in a therapeutic composition for topical application the skin that also comprises at least one penetration enhancer and a fugitive solvent base.
摘要翻译：使用至少一种硅氧烷来改变治疗组合物中活性化合物的释放曲线，用于局部施用皮肤，其还包含至少一种渗透增强剂和缓冲溶剂基质。

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