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1. 发明授权

US08211171B2 Transcatheter coronary sinus mitral valve annuloplasty procedure and coronary artery and myocardial protection device 有权
标题翻译：经导管冠状窦二尖瓣瓣环成形术和冠状动脉及心肌保护装置
公开(公告)号：US08211171B2
公开(公告)日：2012-07-03
申请号：US12514990
申请日：2007-11-13
申请人： June-Hong Kim , Robert J. Lederman , Ozgur Kocaturk
发明人： June-Hong Kim , Robert J. Lederman , Ozgur Kocaturk
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61F2/06 , A61F2002/068 , A61F2210/0014 , A61F2220/0075 , A61F2230/0045 , A61F2250/0037 , A61F2250/0065 , A61M25/0041 , A61M2025/0042 , A61M2025/0059
摘要： A protective device or bridge (20) comprising a central arch (24) is suitable to be placed between an annuplasty device placed in the coronary sinus and an underlying coronary artery to inhibit transmission of compressive force on the coronary artery by the annuplasty device.
摘要翻译：包括中心拱形物（24）的保护装置或桥梁（20）适于放置在放置在冠状窦内的平息装置和下面的冠状动脉之间，以通过平喘装置阻止冠状动脉上的压力传递。

2. 发明授权

US09579200B2 Methods and devices for transcatheter cerclage annuloplasty 有权
标题翻译：经导管环扎瓣膜成形术的方法和装置
公开(公告)号：US09579200B2
公开(公告)日：2017-02-28
申请号：US13824198
申请日：2011-09-15
申请人： Robert J. Lederman , Ozgur Kocaturk
发明人： Robert J. Lederman , Ozgur Kocaturk
IPC分类号： A61B17/24 , A61F2/24 , A61B17/00 , A61B17/221 , A61B17/02 , A61B17/22
CPC分类号： A61F2/2451 , A61B17/00234 , A61B17/221 , A61B2017/00243 , A61B2017/00314 , A61B2017/00327 , A61B2017/0237 , A61B2017/22035 , A61B2090/3966 , A61F2/2466
摘要： Devices, apparatus, and methods for catheter-based repair of cardiac valves, including transcatheter-mitral-valve-cerclage annuloplasty and transcatheter-mitral-valve reapposition. In particular, a target and capture device is provided for guiding a cerclage traversal catheter system through a cerclage trajectory, particularly through a reentry site of the cerclage trajectory. The target and capture device provides the user with a target through which the cerclage traversal catheter system must be guided, particularly under imaging guidance, so as to properly traverse the cerclage trajectory at any desired location, particularly at a reentry site. The target and capture device can, further, ensnare and externalize the cerclage traversal catheter system.
摘要翻译：用于心脏瓣膜基于导管的修复的装置，装置和方法，包括经导管 - 二尖瓣 - 环扎瓣环成形术和经导管 - 二尖瓣重新置入。特别地，提供了目标和捕获装置，用于通过环扎轨迹引导环扎穿越导管系统，特别是通过环扎轨迹的折返部位。目标和捕获装置为使用者提供了一种目标，特别是在成像引导下，必须引导环扎穿越导管系统，以便在任何所需位置，特别是再入位置适当地穿过环扎轨迹。目标和捕获装置还可以进一步包围和外部化环扎穿越导管系统。

3. 发明申请

US20130274591A1 SINGLE CHANNEL MRI GUIDEWIRE 审中-公开
标题翻译：单通道MRI指南
公开(公告)号：US20130274591A1
公开(公告)日：2013-10-17
申请号：US13977557
申请日：2012-01-04
申请人： Merdim Sonmez , Ozgur Kocaturk , Christina E. Saikus
发明人： Merdim Sonmez , Ozgur Kocaturk , Christina E. Saikus
IPC分类号： A61B5/00 , A61B5/01 , A61B5/055
CPC分类号： A61B5/055 , A61B5/01 , A61B5/066 , A61B5/6851 , A61B2562/00 , G01R33/287 , G01R33/34 , G01R33/34053 , G01R33/3628
摘要： The present application discloses a guidewire for magnetic resonance imaging with a single channel design to reduce complexity and to provide conspicuous tip visibility under MRI. In one embodiment, a guidewire body includes an antenna formed from a rod and a helical coil coupled together. The helical coil can have multiple windings without any gaps between the windings. The rod passes through the windings of the helical coil and is coupled to the helical coil using a conductive joint positioned at an end of the rod and at an end of the helical coil. Insulation can be positioned between the rod and the windings of the helical coil. The configuration allows visibility of the antenna along the length of a rod, except where it enters the windings of the coil. Thus, the tip visibility is enhanced as being separated from the rod.
摘要翻译：本申请公开了一种用于具有单通道设计的磁共振成像的导丝，以降低复杂性并在MRI下提供显着的尖端可见性。在一个实施例中，导丝主体包括由杆形成的天线和联接在一起的螺旋线圈。螺旋线圈可以具有多个绕组，在绕组之间没有任何间隙。杆穿过螺旋线圈的绕组并且使用位于杆的端部处并且在螺旋线圈的端部处的导电接头联接到螺旋线圈。绝缘可以位于杆和螺旋线圈的绕组之间。该配置允许天线沿着杆的长度的可视性，除了它进入线圈的绕组之外。因此，与棒分离时，尖端可见度增强。

4. 发明授权

US09271833B2 Transcatheter coronary sinus mitral valve annuloplasty procedure and coronary artery and myocardial protection device 有权
标题翻译：经导管冠状窦二尖瓣瓣环成形术和冠状动脉及心肌保护装置
公开(公告)号：US09271833B2
公开(公告)日：2016-03-01
申请号：US13468761
申请日：2012-05-10
申请人： June-Hong Kim , Robert J. Lederman , Ozgur Kocaturk
发明人： June-Hong Kim , Robert J. Lederman , Ozgur Kocaturk
IPC分类号： A61F2/24 , A61F2/06 , A61M25/00
CPC分类号： A61F2/2451 , A61F2/06 , A61F2002/068 , A61F2210/0014 , A61F2220/0075 , A61F2230/0045 , A61F2250/0037 , A61F2250/0065 , A61M25/0041 , A61M2025/0042 , A61M2025/0059
摘要： A protective device or bridge comprising a central arch is suitable to be placed between an annuplasty device placed in the coronary sinus and an underlying coronary artery to inhibit transmission of compressive force on the coronary artery by the annuplasty device.
摘要翻译：包括中央拱形物的保护装置或桥梁适于放置在放置在冠状窦内的平喘装置和下面的冠状动脉之间，以通过平喘装置阻止冠状动脉上的压力传递。

5. 发明申请

US20130172729A1 ACTIVE ADAPTIVE DETUNING SYSTEMS AND METHODS FOR INTERVENTIONAL DEVICES 有权
标题翻译：主动自适应解调系统和传统设备的方法
公开(公告)号：US20130172729A1
公开(公告)日：2013-07-04
申请号：US13805454
申请日：2011-07-01
申请人： Ozgur Kocaturk
发明人： Ozgur Kocaturk
IPC分类号： A61B5/055
CPC分类号： A61B5/055 , G01R33/285 , G01R33/34084 , G01R33/3657
摘要： Active MRI compatible interventional devices, such as catheters, include at least one RF antenna so that they are visible under MRI analysis. However, metallic structures within intravascular devices may heat up significantly during interventional MRI procedures due to eddy current formation over the conductive transmission lines. The electrical field coupling that occurs between interventional devices and RF signals depend on the position and orientation of interventional device within the bore and the insertion length of the interventional device. The system detects an induced current signal during RF transmission phase and selectively adjusts the impedance value associated with the interventional device by using a varactor and integrated circuit components in such a manner that the currents induced in the interventional device are below a threshold current level, thereby controlling current levels and heating in the interventional device.
摘要翻译：主动MRI兼容的介入装置，例如导管，包括至少一个RF天线，使得它们在MRI分析下是可见的。然而，由于导电传输线上的涡流形成，介入MRI程序期间血管内装置内的金属结构可能会显着升温。在介入装置和RF信号之间发生的电场耦合取决于介入装置在孔内的位置和取向以及介入装置的插入长度。该系统在射频发射阶段检测感应电流信号，并通过使用变容二极管和集成电路组件以使得在介入装置中感应的电流低于阈值电流水平的方式选择性地调节与介入装置相关联的阻抗值，由此控制介入装置中的电流水平和加热。

6. 发明申请

US20100049314A1 TRANSCATHETER CORONARY SINUS MITRAL VALVE ANNULOPLASTY PROCEDURE AND CORONARY ARTERY AND MYOCARDIAL PROTECTION DEVICE 有权
标题翻译：血管内皮冠状动脉麻醉手术和冠状动脉和心肌保护装置
公开(公告)号：US20100049314A1
公开(公告)日：2010-02-25
申请号：US12514990
申请日：2007-11-13
申请人： June-Hong Kim , Robert J. Lederman , Ozgur Kocaturk
发明人： June-Hong Kim , Robert J. Lederman , Ozgur Kocaturk
IPC分类号： A61F2/24 , A61L17/00
CPC分类号： A61F2/2451 , A61F2/06 , A61F2002/068 , A61F2210/0014 , A61F2220/0075 , A61F2230/0045 , A61F2250/0037 , A61F2250/0065 , A61M25/0041 , A61M2025/0042 , A61M2025/0059
摘要： A protective device or bridge (20) comprising a central arch (24) is suitable to be placed between an annuplasty device placed in the coronary sinus and an underlying coronary artery to inhibit transmission of compressive force on the coronary artery by the annuplasty device.
摘要翻译：包括中心拱形物（24）的保护装置或桥梁（20）适于放置在放置在冠状窦内的平息装置和下面的冠状动脉之间，以通过平喘装置阻止冠状动脉上的压力传递。

7. 发明授权

US09486158B2 Active adaptive detuning systems and methods for interventional devices 有权
标题翻译：主动自适应失谐系统和介入装置的方法
公开(公告)号：US09486158B2
公开(公告)日：2016-11-08
申请号：US13805454
申请日：2011-07-01
申请人： Ozgur Kocaturk
发明人： Ozgur Kocaturk
IPC分类号： A61B5/055 , G01R33/36 , G01R33/28 , G01R33/34
CPC分类号： A61B5/055 , G01R33/285 , G01R33/34084 , G01R33/3657
摘要： Active MRI compatible interventional devices, such as catheters, include at least one RF antenna so that they are visible under MRI analysis. However, metallic structures within intravascular devices may heat up significantly during interventional MRI procedures due to eddy current formation over the conductive transmission lines. The electrical field coupling that occurs between interventional devices and RF signals depend on the position and orientation of interventional device within the bore and the insertion length of the interventional device. The system detects an induced current signal during RF transmission phase and selectively adjusts the impedance value associated with the interventional device by using a varactor and integrated circuit components in such a manner that the currents induced in the interventional device are below a threshold current level, thereby controlling current levels and heating in the interventional device.
摘要翻译：主动MRI兼容的介入装置，例如导管，包括至少一个RF天线，使得它们在MRI分析下是可见的。然而，由于导电传输线上的涡流形成，介入MRI程序期间血管内装置内的金属结构可能会显着升温。在介入装置和RF信号之间发生的电场耦合取决于介入装置在孔内的位置和取向以及介入装置的插入长度。该系统在射频发射阶段检测感应电流信号，并通过使用变容二极管和集成电路组件以使得在介入装置中感应的电流低于阈值电流水平的方式选择性地调节与介入装置相关联的阻抗值，由此控制介入装置中的电流水平和加热。

8. 发明授权

US08478381B2 MRI guidewire 有权
标题翻译： MRI导丝
公开(公告)号：US08478381B2
公开(公告)日：2013-07-02
申请号：US12810481
申请日：2008-12-31
申请人： Ozgur Kocaturk
发明人： Ozgur Kocaturk
IPC分类号： A61B5/055
CPC分类号： A61M25/09 , A61B5/055 , A61M2205/3515 , G01R33/287 , G01R33/34084
摘要： A guidewire (100) for use with interventional magnetic resonance imaging has a guidewire body (102) having a distal end and a proximal end and reserving a space therein, a dipole antenna (108) disposed in the space reserved within the guidewire body, the dipole antenna being adapted to be electrically connected to a signal processing system through a first signal channel (110) through the proximal end of the guidewire body, and a loop antenna (112) disposed in the space reserved within the guidewire body toward the distal end of the guidewire body, the loop antenna (112) being adapted to be electrically connected to the signal processing system through a second signal channel (114) through the proximal end of the guidewire body. The dipole antenna and the loop antenna are each constructed to receive magnetic resonance imaging signals independently of each other and to transmit received signals through the first and second signal channels, respectively, to be received by the signal processing system. An interventional magnetic resonance imaging system includes an active guidewire.
摘要翻译：用于介入磁共振成像的导丝（100）具有导线主体（102），其具有远端和近端并在其中保留空间;设置在保持在导丝主体内的空间中的偶极天线（108），偶极天线适于通过穿过导线主体的近端的第一信号通道（110）电连接到信号处理系统;以及环形天线（112），其设置在保持在导丝主体内的空间中朝向远端所述环形天线（112）适于通过穿过所述导丝主体的近端的第二信号通道（114）与所述信号处理系统电连接。偶极天线和环形天线各自被构造成彼此独立地接收磁共振成像信号，并且分别通过第一和第二信号信道发送接收信号以由信号处理系统接收。介入磁共振成像系统包括主动导丝。

9. 发明申请

US20100280359A1 MRI GUIDEWIRE 有权
标题翻译： MRI指南
公开(公告)号：US20100280359A1
公开(公告)日：2010-11-04
申请号：US12810481
申请日：2008-12-31
申请人： Ozgur Kocaturk
发明人： Ozgur Kocaturk
IPC分类号： A61B5/055 , A61M25/09
CPC分类号： A61M25/09 , A61B5/055 , A61M2205/3515 , G01R33/287 , G01R33/34084
摘要： A guidewire (100) for use with interventional magnetic resonance imaging has a guidewire body (102) having a distal end and a proximal end and reserving a space therein, a dipole antenna (108) disposed in the space reserved within the guidewire body, the dipole antenna being adapted to be electrically connected to a signal processing system through a first signal channel (110) through the proximal end of the guidewire body, and a loop antenna (112) disposed in the space reserved within the guidewire body toward the distal end of the guidewire body, the loop antenna (112) being adapted to be electrically connected to the signal processing system through a second signal channel (114) through the proximal end of the guidewire body. The dipole antenna and the loop antenna are each constructed to receive magnetic resonance imaging signals independently of each other and to transmit received signals through the first and second signal channels, respectively, to be received by the signal processing system. An interventional magnetic resonance imaging system includes an active guidewire.
摘要翻译：用于介入磁共振成像的导丝（100）具有导线主体（102），其具有远端和近端并在其中保留空间;设置在保持在导丝主体内的空间中的偶极天线（108），偶极天线适于通过穿过导线主体的近端的第一信号通道（110）电连接到信号处理系统;以及环形天线（112），其设置在保持在导丝主体内的空间中朝向远端所述环形天线（112）适于通过穿过所述导丝主体的近端的第二信号通道（114）与所述信号处理系统电连接。偶极天线和环形天线各自被构造成彼此独立地接收磁共振成像信号，并且分别通过第一和第二信号信道发送接收信号以由信号处理系统接收。介入磁共振成像系统包括主动导丝。

10. 发明申请

US20130211510A1 METHODS AND DEVICES FOR TRANSCATHETER CERCLAGE ANNULOPLASTY 有权
标题翻译：用于血管内皮细胞生长因子的方法和装置
公开(公告)号：US20130211510A1
公开(公告)日：2013-08-15
申请号：US13824198
申请日：2011-09-15
申请人： Robert J. Lederman , Ozgur Kocaturk
发明人： Robert J. Lederman , Ozgur Kocaturk
IPC分类号： A61F2/24
CPC分类号： A61F2/2451 , A61B17/00234 , A61B17/221 , A61B2017/00243 , A61B2017/00314 , A61B2017/00327 , A61B2017/0237 , A61B2017/22035 , A61B2090/3966 , A61F2/2466
摘要： Devices, apparatus, and methods for catheter-based repair of cardiac valves, including transcatheter-mitral-valve-cerclage annuloplasty and transcatheter-mitral-valve reapposition. In particular, a target and capture device is provided for guiding a cerclage traversal catheter system through a cerclage trajectory, particularly through a reentry site of the cerclage trajectory. The target and capture device provides the user with a target through which the cerclage traversal catheter system must be guided, particularly under imaging guidance, so as to properly traverse the cerclage trajectory at any desired location, particularly at a reentry site. The target and capture device can, further, ensnare and externalize the cerclage traversal catheter system.
摘要翻译：用于心脏瓣膜基于导管的修复的装置，装置和方法，包括经导管 - 二尖瓣 - 环扎瓣环成形术和经导管 - 二尖瓣重新置入。特别地，提供了目标和捕获装置，用于通过环扎轨迹引导环扎穿越导管系统，特别是通过环扎轨迹的折返部位。目标和捕获装置为使用者提供了一种目标，特别是在成像引导下，必须引导环扎穿越导管系统，以便在任何所需位置，特别是再入位置适当地穿过环扎轨迹。目标和捕获装置还可以进一步包围和外部化环扎穿越导管系统。

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