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    • 6. 发明授权
    • Method of making fluorinated alkoxy carboxylic acids and precursors thereof
    • 氟化烷氧基羧酸及其前体的制备方法
    • US08440858B2
    • 2013-05-14
    • US13133734
    • 2009-11-24
    • Tilman ZippliesKlaus HintzerOleg Shyshkov
    • Tilman ZippliesKlaus HintzerOleg Shyshkov
    • C07C51/08
    • C07C255/13C07C51/08C07C59/135C07C67/08C07C69/708C07C247/04C07C253/14
    • A method for preparing saturated partially fluorinated alkoxy carboxylic acids or salts thereof by treating a compound: (II), where Rf represents a fluorinated, linear or branched alkyl residue interruptible by one or more oxygen atoms, n is 0 or 1, with a Z-anion in a reaction medium comprising water and an organic solvent, where the Z-anion is selected from CN—, SCN— and OCN— or combinations thereof. A method of making partially fluorinated ethers of the general formula (I) wherein Rf is defined as above, n is 0 or 1, and Z is nitrile (—CN), azide (—N3), thiocyanate (—SCN) or cyanate (—OCN) group, said method comprising treating a fluorinated olefin of the general formula (II) wherein the Z-anion is CN—, OCN—, SCN— or N3−. A compound of the general formula (I) as previously described where Z is selected from SCN, OCN and N3.
    • 通过处理化合物(II)制备饱和部分氟化的烷氧基羧酸或其盐的方法,其中Rf表示可被一个或多个氧原子中断的氟化的直链或支链烷基,n为0或1,Z为 阴离子在包含水和有机溶剂的反应介质中,其中Z-阴离子选自CN-,SCN-和OCN-或其组合。 制备通式(I)的部分氟化醚的方法,其中Rf定义如上,n为0或1,Z为腈(-CN),叠氮化物(-N 3),硫氰酸酯(-SCN)或氰酸酯 -OCN)基团,所述方法包括处理通式(II)的氟化烯烃,其中Z-阴离子是CN-,OCN-,SCN-或N 3 - 。 其中Z选自SCN,OCN和N 3,如前所述的通式(I)的化合物。
    • 7. 发明申请
    • METHODS OF PREPARING FLUORINATED CARBOXYLIC ACIDS AND THEIR SALTS
    • 制备氟化羧酸及其盐的方法
    • US20120184770A1
    • 2012-07-19
    • US13497173
    • 2010-10-21
    • Klaus HintzerDennis E. VogelMiguel A. GuerraJolanta IgnatowskaGerd-Volker RöschenthalerOleg ShyshkovKim M VogelTilman C. Zipplies
    • Klaus HintzerDennis E. VogelMiguel A. GuerraJolanta IgnatowskaGerd-Volker RöschenthalerOleg ShyshkovKim M VogelTilman C. Zipplies
    • C07C51/16C07C51/285C07C51/305C07C51/23C25B3/02C07C51/27C07C51/29
    • C07C51/27C07C53/21C07C59/135
    • A method for preparing fluorinated carboxylic acids and theirs salts is described comprising subjecting a fluorinated alcohol of the general formula (A): A-CH2—OH to at least one first and at least one second oxidizing agent to produce a highly fluorinated carboxylic acid or their salts of the general formula (B): A-COO M+, wherein M+ represents a cation and wherein A in formulas (A) and (B) is the same and A represents the residue: Rf-[0]p-CX″Y″-[0]m-CX′Y′-[0]n-CXY— wherein Rf represents a fluorinated alkyl residue which may or may not contain one or more catenary oxygen atoms, p, m and n are independently from each other either 1 or O, X, X′, X″, Y, Y′ and Y″ are independently from each other H, F, CF3, or C2F5 with the proviso that not all of X, X′, X″, Y, Y′ and Y″ are H; or A represents the residue: R—CFX— wherein X and R are independently selected from a hydrogen, a halogen, or an alkyl, alkenyl, cycloalkyl, or aryl residue, which may or may not contain one or more fluorine atoms and which may or may not contain one or more catenary oxygen atoms; wherein said at least one first oxidizing agent is a compound that can be converted, by action of the second oxidizing agent, into a reactive species capable of oxidizing the fluorinated alcohol.
    • 描述了制备氟化羧酸及其盐的方法,其包括将通式(A)的氟化醇:A-CH 2 -OH置于至少一种第一和至少一种第二氧化剂中以产生高度氟化的羧酸或 其通式(B)的盐:A-COO M +,其中M +表示阳离子,式(A)和(B)中的A相同,A表示残基:Rf- [0] p-CX“ Y“ - [0] m-CX'Y' - [0] n-CXY-其中Rf表示可以或可以不含有一个或多个链状氧原子的氟化烷基残基,p,m和n彼此独立地 1或O,X,X',X“,Y,Y'和Y”彼此独立地为H,F,CF 3或C 2 F 5,条件是不是全部X,X',X“,Y, Y'和Y“为H; 或A表示残基:R-CFX-,其中X和R独立地选自氢,卤素或烷基,烯基,环烷基或芳基残基,其可以含有或不含有一个或多个氟原子, 或者可以不包含一个或多个链状氧原子; 其中所述至少一种第一氧化剂是可以通过第二氧化剂的作用转化成能够氧化氟化醇的反应性物质的化合物。