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1. 发明授权

US09999722B2 Portable medical fluid delivery device with drive screw articulated with reservoir plunger 有权
公开(公告)号：US09999722B2
公开(公告)日：2018-06-19
申请号：US13142912
申请日：2009-12-30
申请人： Ofer Yodfat , Shai Ben-David
发明人： Ofer Yodfat , Shai Ben-David
IPC分类号： A61M5/145 , A61M5/142 , A61M5/14 , A61M5/315
CPC分类号： A61M5/1456 , A61M5/1413 , A61M5/142 , A61M5/14244 , A61M5/14248 , A61M5/145 , A61M5/1452 , A61M5/31513 , A61M5/31515 , A61M2005/14268 , A61M2005/14506 , A61M2005/14533 , A61M2005/14573
摘要： A device for delivering fluid into the body is provided. The device may comprise a reservoir including at least one wall for retaining fluid and a plunger (400), wherein the plunger is articulated with a drive screw (300) having a distal end (304) that rotates within the plunger and displaces the plunger in a linear direction. The device may further comprise a reusable part having a motor, one or more gears and a receiving portion, and also a disposable part having a reservoir, a plunger and a drive screw having a proximal end capable of engaging with the receiving portion upon connecting the reusable part and the disposable part

2. 发明授权

US09446185B2 Devices and methods for improving accuracy of fluid delivery 有权
标题翻译：用于提高流体输送精度的装置和方法
公开(公告)号：US09446185B2
公开(公告)日：2016-09-20
申请号：US12921702
申请日：2009-03-12
申请人： Ofer Yodfat , Avihoo P. Keret
发明人： Ofer Yodfat , Avihoo P. Keret
IPC分类号： A61M5/142 , A61M5/168 , F04B43/12
CPC分类号： A61M5/14232 , A61M5/14248 , A61M5/16804 , A61M5/16831 , A61M5/16877 , A61M2205/50 , F04B43/1253
摘要： Devices and methods for delivering therapeutic fluid to a patient's body are described. The devices may comprise a dispensing unit having a reservoir, a driving mechanism having a movable member for delivering therapeutic fluid to a patient's body, at least one sensor for sensing a relative position of the movable member and generating a signal, and a processor for controlling the driving mechanism to deliver an amount of therapeutic fluid that compensates for a change in the flow of the therapeutic fluid occurring during fluid delivery. The methods may be implemented by operating the driving mechanism, receiving a signal based on the position of the movable member, determining an amount of therapeutic fluid to deliver, and controlling the driving mechanism to deliver an amount of fluid that compensates for a change in flow occurring during fluid delivery.
摘要翻译：描述了将治疗流体递送到患者身体的装置和方法。所述装置可以包括具有储存器的分配单元，具有用于将治疗流体递送到患者身体的可移动构件的驱动机构，用于感测可移动构件的相对位置并产生信号的至少一个传感器，以及用于控制用于输送一定量的治疗液体的驱动机构，其补偿在流体递送期间发生的治疗性流体的流动的变化。这些方法可以通过操作驱动机构，基于可移动部件的位置接收信号，确定要输送的治疗流体的量，以及控制驱动机构来输送补偿流量变化的流体量来实现在流体输送期间发生。

3. 发明授权

US09248232B2 Analyte monitoring and fluid dispensing system 有权
标题翻译：分析物监测和流体分配系统
公开(公告)号：US09248232B2
公开(公告)日：2016-02-02
申请号：US13511578
申请日：2010-11-30
申请人： Ofer Yodfat , Eli Znati , Illai Gescheit , Avraham Neta , Offer Levy
发明人： Ofer Yodfat , Eli Znati , Illai Gescheit , Avraham Neta , Offer Levy
IPC分类号： A61M31/00 , A61M5/168 , A61M5/142 , A61B5/145 , A61B5/1486 , A61M5/14 , A61M5/145 , A61M5/172 , A61B5/00 , A61M5/00
CPC分类号： A61M5/14248 , A61B5/1451 , A61B5/14532 , A61B5/14865 , A61B5/4839 , A61M5/002 , A61M5/1413 , A61M5/1456 , A61M5/1723 , A61M2005/14252 , A61M2005/14268 , A61M2005/1726 , A61M2205/3317 , A61M2205/3569 , A61M2205/3592 , A61M2209/01 , A61M2230/201
摘要： Embodiments of the present disclosure are directed to a skin adherable device for delivering therapeutic fluid into a body of a patient. In some embodiments, the device includes a monitoring apparatus, a pump, and a tip for delivering the therapeutic fluid into the body of the patient and for monitoring bodily analyte in the body of the patient. The pump may continuously deliver the therapeutic fluid to the body of the patient and the monitoring apparatus may continuously monitor bodily analytes of the patient.
摘要翻译：本公开的实施例涉及用于将治疗性流体输送到患者体内的皮肤粘附装置。在一些实施例中，该装置包括监测装置，泵和用于将治疗流体输送到患者体内并用于监测患者体内的身体分析物的尖端。泵可以将治疗流体连续递送到患者体内，并且监测装置可以连续地监测患者的身体分析物。

4. 发明授权

US08814822B2 Reciprocating delivery of fluids to the body with analyte concentration monitoring 有权
标题翻译：通过分析物浓度监测向体内往复运送流体
公开(公告)号：US08814822B2
公开(公告)日：2014-08-26
申请号：US12116546
申请日：2008-05-07
申请人： Ofer Yodfat , Ruthy Kaidar , Gali Shapira
发明人： Ofer Yodfat , Ruthy Kaidar , Gali Shapira
IPC分类号： A61M31/00
CPC分类号： A61B5/14865 , A61B5/14532 , A61B5/150022 , A61B5/150229 , A61B5/150389 , A61B5/150503 , A61B5/157 , A61B5/4839 , A61B5/6848 , A61B2560/0412 , A61B2560/0443 , A61M5/14248 , A61M5/1723 , A61M2005/1726
摘要： A volume of an analyte-enriched fluid can be withdrawn out of a user's subcutaneous compartment using a patch unit that includes a reversible pumping mechanism. The volume can be withdrawn out of the body and into the patch unit through a cannula inserted into the subcutaneous compartment so that an analyte concentration in the volume can be measured using a sensing element within the patch unit. After analyte concentration analysis, at least the volume can be delivered back into the subcutaneous compartment by operating the pumping mechanism in a forward direction. biologically compatible fluid can optionally be pumped into the subcutaneous compartment from a reservoir in the patch unit and then allowed to partially or completely equilibrate with the analyte concentration in the interstitial fluid of the subcutaneous compartment via a permeable or semi-permeable cannula surface before being drawn back into the patch unit for analysis. Related systems, apparatus, methods, and/or articles are also described.
摘要翻译：可以使用包括可逆泵送机构的贴片单元将一定体积的富含分析物的流体从使用者的皮下隔室中取出。体积可以通过插入到皮下室中的插管从体内抽出并进入贴片单元，使得可以使用贴片单元内的感测元件来测量体积中的分析物浓度。在分析物浓度分析之后，通过沿向前的方向操作泵送机构，至少体积可被输送回皮下室。生物相容的流体可以任选地从贴片单元中的储器泵入皮下隔室中，然后在被拉伸之前通过可渗透或半渗透的套管表面部分地或完全地与皮下室的间质液中的分析物浓度平衡回到补丁单位进行分析。还描述了相关系统，装置，方法和/或制品。

5. 发明授权

US08747348B2 Detachable portable infusion device 有权
标题翻译：可拆卸便携式输液装置
公开(公告)号：US08747348B2
公开(公告)日：2014-06-10
申请号：US13419182
申请日：2012-03-13
申请人： Ofer Yodfat , Danna Perlman
发明人： Ofer Yodfat , Danna Perlman
IPC分类号： A61M5/168
CPC分类号： A61M5/14248 , A61M5/1413 , A61M5/1723 , A61M2005/14268 , A61M2205/14 , A61M2205/3569 , A61M2205/3592
摘要： A portable therapeutic apparatus and a method for controlling the apparatus are provided. In one aspect the apparatus and the method can be implemented using a patch unit (100, 200) removably attachable to a cradle unit (20), said cradle unit removably attachable to the body of the patient; a position detector (1000) comprising a patch portion (900) and a cradle portion (800), said patch portion coupled to the patch unit, said cradle portion coupled to the cradle unit; a processor adapted for receiving a position indication signal from the at least one position detector, said position indication signal corresponding to a physical proximity of the patch portion to the cradle portion, and, wherein the portable therapeutic apparatus is adapted for at least one therapeutic function selected from the group consisting of delivering a therapeutic fluid into the body of the patient and sensing a bodily analyte.
摘要翻译：提供一种便携式治疗仪器和一种用于控制该装置的方法。在一个方面，所述装置和方法可以使用可移除地附接到支架单元（20）的贴片单元（100,200）来实现，所述支架单元可移除地附接到患者身体; 位置检测器（1000），包括贴片部分（900）和支架部分（800），所述贴片部分耦合到贴片单元，所述支架部分联接到支架单元; 适于从所述至少一个位置检测器接收位置指示信号的处理器，所述位置指示信号对应于所述补片部分到所述支架部分的物理接近，并且其中所述便携式治疗仪适用于至少一种治疗功能选自将治疗流体递送到患者体内并感测身体分析物的组。

6. 发明授权

US08679062B2 Apparatus and method for pumping fluid 失效
标题翻译：用于泵送流体的装置和方法
公开(公告)号：US08679062B2
公开(公告)日：2014-03-25
申请号：US12082295
申请日：2008-04-10
申请人： Ofer Yodfat , Ofer Arnold , Avraham Neta
发明人： Ofer Yodfat , Ofer Arnold , Avraham Neta
IPC分类号： A61M1/00 , A61M37/00
CPC分类号： A61M5/14248 , A61M2005/14252 , A61M2005/14264 , A61M2005/14268 , A61M2005/1583 , A61M2005/1585
摘要： Methods, systems, and apparatuses for delivering therapeutic fluid to a user are disclosed. The apparatus includes a pump mechanism for pumping therapeutic fluid to the user having a reusable part which includes a housing and a disposable part configured to be inserted into the housing of the reusable part and to be connected with the reusable part. The connection of the reusable part and the disposable part enables operation of the pump mechanism and disconnection of the reusable part and the disposable part disables operation of the pump mechanism.
摘要翻译：公开了用于向用户输送治疗流体的方法，系统和装置。该装置包括用于将治疗流体泵送到使用者的泵机构，其具有可重复使用部分，该可再利用部分包括壳体和被配置为插入到可再使用部件的壳体中并与可再利用部件连接的一次性部件。可重复使用部件和一次性部件的连接使得泵机构能够操作，并且可重复使用部件和一次性部件的断开使泵机构的操作失效。

7. 发明授权

US08641672B2 Infusion and sensing device with battery charging and data transferring mechanisms 有权
标题翻译：具有电池充电和数据传输机制的输液和感应装置
公开(公告)号：US08641672B2
公开(公告)日：2014-02-04
申请号：US12921824
申请日：2009-03-10
申请人： Ofer Yodfat , Avihoo P. Keret , Avraham Neta , Illai Gescheit , Tsabar Mor
发明人： Ofer Yodfat , Avihoo P. Keret , Avraham Neta , Illai Gescheit , Tsabar Mor
IPC分类号： A61M1/00
CPC分类号： A61M5/14248 , A61M5/14216 , A61M5/14232 , A61M5/1456 , A61M5/14566 , A61M5/1723 , A61M2005/14268 , A61M2005/14573 , A61M2005/1726 , A61M2205/0266 , A61M2205/3561 , A61M2205/3569 , A61M2205/3592 , A61M2205/52 , A61M2205/8206 , A61M2205/8243 , A61M2205/8262 , A61M2205/8293 , A61M2209/086
摘要： Disclosed is a portable ambulatory fluid delivery device. The device includes a dispensing unit to dispense therapeutic fluid, the dispensing unit including one or more rechargeable batteries, a housing to retain the one or more rechargeable batteries, a reservoir to contain the therapeutic fluid, a driving mechanism to cause delivery of the therapeutic fluid from the reservoir to a user's body, and at least one electrical connector to be coupled to a recharging unit to direct electrical power received from the recharging unit to recharge the one or more rechargeable batteries. At least a portion of the housing is securable to a skin of the user.
摘要翻译：公开了一种便携式便携式流体输送装置。所述装置包括分配单元以分配治疗流体，所述分配单元包括一个或多个可再充电电池，用于保持所述一个或多个可再充电电池的壳体，用于容纳所述治疗流体的储存器，用于使所述治疗流体输送的驱动机构以及至少一个要连接到再充电单元的电连接器，以引导从所述再充电单元接收的电力对所述一个或多个可再充电电池进行再充电。壳体的至少一部分可固定到使用者的皮肤上。

8. 发明授权

US08636041B2 Methods and devices for delivering fluid to a reservoir of a fluid delivery device 失效
标题翻译：用于将流体输送到流体输送装置的储存器的方法和装置
公开(公告)号：US08636041B2
公开(公告)日：2014-01-28
申请号：US11989680
申请日：2007-08-16
申请人： Ofer Yodfat
发明人： Ofer Yodfat
IPC分类号： B65B1/04
CPC分类号： A61J1/2096 , A61J1/201 , A61J1/2058 , A61M5/14244 , A61M5/14248 , A61M2005/14268 , A61M2209/045
摘要： Medical devices and methods for delivering therapeutic fluids transcutaneously to a body of a patient via a fluid delivery device and an adapter is provided. A Luer slip connector is provided at a first connecting end of the adapter. A therapeutic fluid container is connected with the second connecting end such that the container's neck is received in the second connecting end and a hollow penetrating member provided in the adapter punctures the septum of the container to admit the therapeutic fluid into a needle-less syringe from the container. After, fluid emerges from the tip of the penetrating member, the second connecting end of the adapter is attached to the fluid delivery device, thereby filling the reservoir with the fluid and pushing the syringe plunger forward to inject fluid into reservoir.
摘要翻译：提供了经由流体输送装置和适配器将治疗性流体经皮递送至患者身体的医疗装置和方法。在适配器的第一连接端设置Luer滑动连接器。治疗性流体容器与第二连接端连接，使得容器的颈部容纳在第二连接端，并且设置在适配器中的中空穿透构件刺穿容器的隔膜，以将治疗流体接纳到无针注射器中容器之后，流体从穿透构件的尖端出来，适配器的第二连接端附接到流体输送装置，从而用流体填充储存器并向前推动注射器柱塞以将流体注入储存器。

9. 发明授权

US08491529B2 Vented dispensing device and method 有权
标题翻译：通气分配装置及方法
公开(公告)号：US08491529B2
公开(公告)日：2013-07-23
申请号：US12452764
申请日：2008-07-20
申请人： Ofer Yodfat , Avraham Neta
发明人： Ofer Yodfat , Avraham Neta
IPC分类号： A61M5/00
CPC分类号： A61M5/16822 , A61B5/14532 , A61B5/1486 , A61M5/142 , A61M5/14244 , A61M5/14248 , A61M5/155 , A61M5/1723 , A61M2005/14204 , A61M2005/14264 , A61M2005/14268 , A61M2205/50 , A61M2205/581 , A61M2205/582 , A61M2205/82 , A61M2207/00
摘要： Disclosed is a fluid dispensing device that includes at least one reservoir to hold the therapeutic fluid, at least one other unit requiring communication with ambient air, at least partly, to operate, and at least one housing defining an interior to retain the at least one reservoir and the at least one other unit. The at least one housing has at least one vent port formed on one or more of its walls. The at least one vent port is adapted to direct or communicate air to maintain pressure equilibrium between the air pressure in the interior of the at least one housing and the ambient air pressure outside the at least one housing, and provide communication with the ambient air to the at least one other unit requiring air to enable operation of the at least one other unit.
摘要翻译：公开了一种流体分配装置，其包括至少一个储存器以保持治疗流体，至少一个其它单元需要至少部分地与环境空气进行通信以操作，并且至少一个壳体限定内部以保持至少一个储存器和至少一个其他单元。至少一个壳体具有形成在其一个或多个壁上的至少一个排气口。所述至少一个通气口适于引导或连通空气，以维持所述至少一个壳体内部的空气压力与所述至少一个壳体外部的环境空气压力之间的压力平衡，并且提供与所述环境空气的连通所述至少一个其他单元需要空气以使得能够操作所述至少一个其他单元。

10. 发明授权

US08465460B2 Device for drug delivery 有权
标题翻译：药物输送装置
公开(公告)号：US08465460B2
公开(公告)日：2013-06-18
申请号：US12733009
申请日：2008-07-31
申请人： Ofer Yodfat , Gavriel J. Iddan , Illai Gescheit
发明人： Ofer Yodfat , Gavriel J. Iddan , Illai Gescheit
IPC分类号： A61M5/178
CPC分类号： A61M5/14248 , A61M5/1413 , A61M5/14232 , A61M5/1424 , A61M5/14244 , A61M5/1454 , A61M5/1456 , A61M2005/1405 , A61M2005/14268 , A61M2205/071 , A61M2209/045
摘要： Disclosed is an ambulatory therapeutic fluid delivery device (10). The device includes at least one housing (200) connectable to a cannula (250), the at least one housing retaining a reservoir (220) to hold the therapeutic fluid. The device also includes a mechanically powered pumping mechanism (150) to cause delivery of at least some of the fluid from the reservoir, and a power-transfer mechanism to transfer manually-delivered power provided by a user to mechanically actuate the pumping mechanism.
摘要翻译：公开了一种移动式治疗液输送装置（10）。该装置包括可连接到套管（250）的至少一个壳体（200），所述至少一个壳体保持储存器（220）以保持治疗流体。该装置还包括机械动力泵送机构（150），用于使来自储存器的至少一些流体的输送以及动力传递机构传递由使用者提供的手动输送的动力以机械地致动泵送机构。

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