专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2016073336A1 MESH MICROFLUIDIC MIXING CHAMBER 审中-公开
标题翻译： MESH微流化混合室
公开(公告)号：WO2016073336A1
公开(公告)日：2016-05-12
申请号：PCT/US2015/058576
申请日：2015-11-02
申请人： ETHEREDGE, Robert , YURKOVETSKY, Yevgeny , OPPENHEIMER, Aaron
发明人： ETHEREDGE, Robert , YURKOVETSKY, Yevgeny , OPPENHEIMER, Aaron
IPC分类号： G01N33/543
CPC分类号： G01N33/54386 , G01N33/54313 , G01N33/54326 , G01N33/54366 , G01N33/56983
摘要： This document provides devices, systems, and methods for detecting pathogens in a biological sample. In some cases, the devices, systems, and methods include a microfluidic device, which includes a biological sample inlet in fluid communication with at least a first microfluidic chamber. The first microfluidic chamber holds a fibrous matrix. The fibrous matrix can carrying anticoagulant and target capture agents within the fibrous matrix. In some cases, the fibrous matrix can be a nonwoven sheet, which can entangle and retain particles bonded to the target capture agents. When in use, a biological sample is introduced into a microfluidic device to flow through the fibrous matrix to mix with the anticoagulant and contact target capture agents. The target capture agents can either remain in the fibrous matrix or flow to a target capture agent chamber. A lysis agent can be delivered through microfluidic chambers including the target capture agent and any captured targets to lyse the target and produce lysate, which can be analyzed to detect a presence of the target in the biological sample.
摘要翻译：本文件提供用于检测生物样品中病原体的装置，系统和方法。在一些情况下，装置，系统和方法包括微流体装置，其包括与至少第一微流体室流体连通的生物样品入口。第一微流体室保持纤维基质。纤维基质可以在纤维基质内携带抗凝血剂和靶捕获剂。在一些情况下，纤维基质可以是非织造片材，其可以缠结并保留结合到靶捕获剂上的颗粒。当使用时，将生物样品引入微流体装置中以流过纤维基质以与抗凝剂和接触目标捕获剂混合。靶捕获剂可以保留在纤维状基质中或流到目标捕获剂室。裂解剂可以通过包括靶捕获剂和任何捕获的靶的微流体室递送以裂解靶并产生裂解物，其可被分析以检测生物样品中目标物的存在。

2. 发明申请

WO2015026911A1 MICROFLUIDIC METERING OF FLUIDS 审中-公开
标题翻译：流体微流量计
公开(公告)号：WO2015026911A1
公开(公告)日：2015-02-26
申请号：PCT/US2014/051838
申请日：2014-08-20
申请人： DAKTARI DIAGNOSTICS, INC. , ZAMIR, Lee , OPPENHEIMER, Aaron , WEBER, Lutz
发明人： ZAMIR, Lee , OPPENHEIMER, Aaron , WEBER, Lutz
IPC分类号： B01L3/00
CPC分类号： B01L3/502738 , B01L3/502723 , B01L3/502776 , B01L2200/0605 , B01L2200/0647 , B01L2200/0684 , B01L2200/10 , B01L2300/0816 , B01L2300/0819 , B01L2300/0864 , B01L2300/0867 , B01L2400/0406 , B01L2400/0487 , B01L2400/0688 , Y10T436/2575
摘要： This document provides methods and devices for metering fluids. In some cases, the methods and devices include intersecting channels that include capillary-stop geometries at each intersection point that guides the fluids on a desired path, which is controlled by the opening and closing of valves. For example, a metering channel can intersect a loading channel and intersect an outflow channel and a metering portion can be defined by the geometry of the metering channel between the intersection points.
摘要翻译：本文档提供了计量流体的方法和设备。在一些情况下，方法和装置包括在每个交叉点处包括毛细管停止几何形状的相交通道，其在通过阀的打开和关闭控制的期望路径上引导流体。例如，计量通道可以与加载通道相交并且与流出通道相交，并且计量部分可以由交叉点之间的计量通道的几何形状限定。

3. 发明申请

WO2012064878A3 COUNTING PARTICLES USING AN ELECTRICAL DIFFERENTIAL COUNTER 审中-公开
标题翻译：使用电动微分计数器计算粒子
公开(公告)号：WO2012064878A3
公开(公告)日：2012-08-16
申请号：PCT/US2011060041
申请日：2011-11-09
申请人： GEN HOSPITAL CORP , MASSACHUSETTS INST TECHNOLOGY , UNIV ILLINOIS , DAKTARI DIAGNOSTICS INC , WATKINS NICHOLAS , BASHIR RASHID , RODRIGUEZ WILLIAM , CHENG XUANHONG , TONER MEHMET , CHEN GRACE , OPPENHEIMER AARON
发明人： WATKINS NICHOLAS , BASHIR RASHID , RODRIGUEZ WILLIAM , CHENG XUANHONG , TONER MEHMET , CHEN GRACE , OPPENHEIMER AARON
IPC分类号： G01N33/53 , C12M1/34 , G01N21/17 , G01N33/52
CPC分类号： G01N27/02 , B01L2200/0652 , B01L2300/0877 , C12M41/36 , G01N15/12 , G01N15/1245 , G01N33/56972 , G01N2015/1006 , G01N2015/1486
摘要： This disclosure relates to methods and devices to count particles of interest, such as cells. The methods include obtaining a fluid sample that may contain particles of interest; counting all types of particles in a portion of the sample using a first electrical differential counter to generate a first total; removing any particles of interest from the portion of the fluid sample; counting any particles remaining in the portion of the fluid sample using a second electrical differential counter after the particles of interest are removed to generate a second total; and calculating a number of particles of interest originally in the fluid sample by subtracting the second total from the first total, wherein the difference is the number of particles of interest in the sample. These methods and related devices can be used, for example, to produce a robust, inexpensive diagnostic kit for CD4+ T cell counting in whole blood samples.
摘要翻译：本公开涉及用于对感兴趣的粒子（诸如细胞）进行计数的方法和设备。该方法包括获得可能含有感兴趣颗粒的流体样品; 使用第一电差分计数器对所述样本的一部分中的所有类型的粒子进行计数以生成第一总和; 从流体样品的该部分去除任何感兴趣的颗粒; 在移除感兴趣的颗粒以产生第二总数之后，使用第二电差分计数器对留在流体样本的该部分中的任何颗粒进行计数; 以及通过从所述第一总数中减去所述第二总数来计算原始在所述流体样本中的感兴趣粒子的数量，其中所述差值是所述样本中的所述感兴趣粒子的数量。例如，可以使用这些方法和相关装置来产生用于全血样品中CD4 + T细胞计数的稳健，便宜的诊断试剂盒。

4. 发明申请

WO2012151527A3 CONDUCTIVE PATTERNS AND METHODS FOR MAKING CONDUCTIVE PATTERNS 审中-公开
标题翻译：导电图案和制作导电图案的方法
公开(公告)号：WO2012151527A3
公开(公告)日：2013-03-21
申请号：PCT/US2012036598
申请日：2012-05-04
申请人： DAKTARI DIAGNOSTICS INC , ETHEREDGE ROBERT WINSTON III , OPPENHEIMER AARON
发明人： ETHEREDGE ROBERT WINSTON III , OPPENHEIMER AARON
IPC分类号： G01N27/02 , B41J2/315 , C12Q1/68 , G01N33/48
CPC分类号： B01L3/502707 , B01L3/502746 , B01L2300/0645 , B01L2300/0825 , B01L2300/161 , B01L2400/0406 , B01L2400/086 , B01L2400/088
摘要： This document provides conductive patterns, electrical sensors including conductive patterns, and methods of making conductive patterns used in electrical sensors. In some cases, the conductive patterns can define one or more microelectrodes. For example, thermal transfer printing techniques are described. In some cases, a microfluidics device can include one or more microelectrodes in a micro-channel.
摘要翻译：本文件提供导电图案，包括导电图案的电传感器以及在电传感器中使用的制作导电图案的方法。在一些情况下，导电图案可以限定一个或多个微电极。例如，描述热转印技术。在一些情况下，微流体装置可包括微通道中的一个或多个微电极。

5. 发明申请

WO2004093648A2 USER INTERFACE FOR INFUSION PUMP REMOTE CONTROLLER AND METHOD OF USING THE SAME 审中-公开
标题翻译：用于输入泵远程控制器的用户界面及其使用方法
公开(公告)号：WO2004093648A2
公开(公告)日：2004-11-04
申请号：PCT/US2004/012005
申请日：2004-04-19
申请人： INSULET CORPORATION , CAMPBELL, Robert , GEMMEL, Steven , VOGT, Marc , GARIBOTTO, John , MALAVE, Luis , CATE-BROWN, Deborah , OPPENHEIMER, Aaron , VIVONA, Christina , MANDLER, Pamela , FREY, David
发明人： CAMPBELL, Robert , GEMMEL, Steven , VOGT, Marc , GARIBOTTO, John , MALAVE, Luis , CATE-BROWN, Deborah , OPPENHEIMER, Aaron , VIVONA, Christina , MANDLER, Pamela , FREY, David
IPC分类号： A61B
CPC分类号： A61M5/172 , A61B5/14532 , A61B2560/0223 , A61B2562/0295 , A61M5/14248 , A61M2205/3569 , A61M2205/3592 , A61M2209/01 , A61M2230/201 , G06F19/00 , G06Q50/22 , G16H40/40
摘要： A control system for controlling an infusion pump, including interface components for allowing a user to receive and provide information, a processor connected to the user interface components and adapted to provide instructions to the infusion pump, and a computer program having setup instructions that cause the processor to enter a setup mode upon the control system first being turned on. In the setup mode, the processor prompts the user, in a sequential manner, through the user interface components to input basic information for use by the processor in controlling the infusion pump, and allows the user to operate the infusion pump only after the user has completed the setup mode.
摘要翻译：一种用于控制输注泵的控制系统，包括用于允许用户接收和提供信息的接口部件，连接到用户接口部件并适于向输注泵提供指令的处理器，以及具有设置指令的计算机程序，处理器在首次打开控制系统时进入设置模式。在设置模式下，处理器以顺序的方式通过用户界面组件提示用户输入基本信息供处理器在控制输液泵中使用，并且允许用户仅在使用者具有完成设置模式。

6. 发明申请

WO2012151527A2 CONDUCTIVE PATTERNS AND METHODS FOR MAKING CONDUCTIVE PATTERNS 审中-公开
标题翻译：导电图案和制作导电图案的方法
公开(公告)号：WO2012151527A2
公开(公告)日：2012-11-08
申请号：PCT/US2012/036598
申请日：2012-05-04
申请人： DAKTARI DIAGNOSTICS, INC. , ETHEREDGE, Robert, Winston, III , OPPENHEIMER, Aaron
发明人： ETHEREDGE, Robert, Winston, III , OPPENHEIMER, Aaron
IPC分类号： G01N27/02 , C12Q1/68 , G01N33/48 , B41J2/315
CPC分类号： B01L3/502707 , B01L3/502746 , B01L2300/0645 , B01L2300/0825 , B01L2300/161 , B01L2400/0406 , B01L2400/086 , B01L2400/088
摘要： This document provides conductive patterns, electrical sensors including conductive patterns, and methods of making conductive patterns used in electrical sensors. In some cases, the conductive patterns can define one or more microelectrodes. For example, thermal transfer printing techniques are described. In some cases, a microfluidics device can include one or more microelectrodes in a micro-channel.
摘要翻译：本文件提供导电图案，包括导电图案的电传感器以及在电传感器中使用的制作导电图案的方法。在一些情况下，导电图案可以限定一个或多个微电极。例如，描述热转印技术。在一些情况下，微流体装置可包括微通道中的一个或多个微电极。

7. 发明申请

WO2012064878A2 COUNTING PARTICLES USING AN ELECTRICAL DIFFERENTIAL COUNTER 审中-公开
标题翻译：使用电气差分计数器计数颗粒
公开(公告)号：WO2012064878A2
公开(公告)日：2012-05-18
申请号：PCT/US2011/060041
申请日：2011-11-09
申请人： THE GENERAL HOSPITAL CORPORATION , MASSACHUSETTS INSTITUTE OF TECHNOLOGY , THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS , DAKTARI DIAGNOSTICS, INC. , WATKINS, Nicholas , BASHIR, Rashid , RODRIGUEZ, William , CHENG, Xuanhong , TONER, Mehmet , CHEN, Grace , OPPENHEIMER, Aaron
发明人： WATKINS, Nicholas , BASHIR, Rashid , RODRIGUEZ, William , CHENG, Xuanhong , TONER, Mehmet , CHEN, Grace , OPPENHEIMER, Aaron
IPC分类号： G01N33/53 , G01N33/52 , G01N21/17 , C12M1/34
CPC分类号： G01N27/02 , B01L2200/0652 , B01L2300/0877 , C12M41/36 , G01N15/12 , G01N15/1245 , G01N33/56972 , G01N2015/1006 , G01N2015/1486
摘要： This disclosure relates to methods and devices to count particles of interest, such as cells. The methods include obtaining a fluid sample that may contain particles of interest; counting all types of particles in a portion of the sample using a first electrical differential counter to generate a first total; removing any particles of interest from the portion of the fluid sample; counting any particles remaining in the portion of the fluid sample using a second electrical differential counter after the particles of interest are removed to generate a second total; and calculating a number of particles of interest originally in the fluid sample by subtracting the second total from the first total, wherein the difference is the number of particles of interest in the sample. These methods and related devices can be used, for example, to produce a robust, inexpensive diagnostic kit for CD4+ T cell counting in whole blood samples.
摘要翻译：本公开涉及计算感兴趣的颗粒例如细胞的方法和装置。所述方法包括获得可含有感兴趣的颗粒的流体样品; 使用第一电差分计数器对样品的一部分中的所有类型的颗粒计数以产生第一总数; 从流体样品的一部分去除任何感兴趣的颗粒; 在除去感兴趣的颗粒之后，使用第二电差速器计数器在流体样品的部分中剩余的任何颗粒计数以产生第二总数; 以及通过从第一个总计中减去第二个总计来计算最初在流体样品中的感兴趣的颗粒数，其中差值是样品中的感兴趣的颗粒数。这些方法和相关装置可用于例如在全血样品中产生用于CD4 + T细胞计数的稳健且廉价的诊断试剂盒。

8. 发明申请

WO2004093648A3 USER INTERFACE FOR INFUSION PUMP REMOTE CONTROLLER AND METHOD OF USING THE SAME 审中-公开
标题翻译：用于输入泵远程控制器的用户界面及其使用方法
公开(公告)号：WO2004093648A3
公开(公告)日：2009-04-09
申请号：PCT/US2004012005
申请日：2004-04-19
申请人： INSULET CORP , CAMPBELL ROBERT , GEMMEL STEVEN , VOGT MARC , GARIBOTTO JOHN , MALAVE LUIS , CATE-BROWN DEBORAH , OPPENHEIMER AARON , VIVONA CHRISTINA , MANDLER PAMELA , FREY DAVID
发明人： CAMPBELL ROBERT , GEMMEL STEVEN , VOGT MARC , GARIBOTTO JOHN , MALAVE LUIS , CATE-BROWN DEBORAH , OPPENHEIMER AARON , VIVONA CHRISTINA , MANDLER PAMELA , FREY DAVID
IPC分类号： A61K9/22 , A61B20060101 , A61B5/00 , A61M5/14 , A61M5/142 , A61M5/172 , G06Q50/22 , G09G5/00
CPC分类号： A61M5/172 , A61B5/14532 , A61B2560/0223 , A61B2562/0295 , A61M5/14248 , A61M2205/3569 , A61M2205/3592 , A61M2209/01 , A61M2230/201 , G06Q50/22 , G16H40/40
摘要： A control system for controlling an infusion pump, including interface components for allowing a user to receive and provide information, a processor connected to the user interface components and adapted to provide instructions to the infusion pump, and a computer program having setup instructions that cause the processor to enter a setup mode upon the control system first being turned on. In the setup mode, the processor prompts the user, in a sequential manner, through the user interface components to input basic information for use by the processor in controlling the infusion pump, and allows the user to operate the infusion pump only after the user has completed the setup mode.
摘要翻译：一种用于控制输注泵的控制系统，包括用于允许用户接收和提供信息的接口部件，连接到用户接口部件并适于向输注泵提供指令的处理器，以及具有设置指令的计算机程序，处理器在首先打开控制系统时进入设置模式。在设置模式下，处理器以顺序的方式通过用户界面组件提示用户输入基本信息供处理器在控制输液泵中使用，并且仅在使用者具有完成设置模式。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式