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    • 8. 发明申请
    • METHOD FOR PRODUCING LONG-CHAIN GLYCINE-N,N-DIACETIC ACID DERIVATIVES
    • 用于生产长链甘氨酸-N,N-二乙酸衍生物
    • WO9910314A3
    • 1999-07-01
    • PCT/EP9805220
    • 1998-08-17
    • BASF AGRAHM RAINERGREINDL THOMASOFTRING ALFREDOETTER GUENTERDETERING JUERGENBRAUN GEROLD
    • RAHM RAINERGREINDL THOMASOFTRING ALFREDOETTER GUENTERDETERING JUERGENBRAUN GEROLD
    • C07C229/08C07C229/16C07C253/00C07C255/25C07D233/72C07D233/74
    • C07C229/08C07C229/16C07C253/00C07C255/25
    • The invention relates to a method for producing compounds of general formula (IIb), wherein R represents C6-C30 alkyl or C6-C30 alkenyl which can also support up to 5 hydroxyl groups, formyl groups, C1-C4 alkoxy groups, phenoxy groups or C1-C4 alkoxycarbonyl groups as substituents and which can be interrupted by up to 5 non-adjacent oxygen atoms, or alkoxylate groupings of formula -(CH2)k-O-(A O)m-(A O)n - Y, wherein A and A represent 1,2 alkylene groups with 2 to 4 C-atoms, Y represents hydrogen, C1-C12 alkyl, phenyl, or C1-C4 alkoxycarbonyl, k represents the number 1, 2 or 3 and m and n each represent numbers from 0 to 50, the sum of m and n being at least 4, independently of each other. According to the inventive method, iminodiacetonitrile is reacted with aldehydes of general formula R-CHO and HCN or alkali cyanides. The method is carried out a) without using an organic solvent and in the presence of a Lewis or Bronsted acid, or b) with or without an organic solvent and in the presence of an emulsifier, or c) with or without an organic solvent and at a pressure of 1 to 40 bar.
    • 在对通式(IIb)的化合物的制备方法,其中R是C6至C30的烷基或C6至C30链烯基,其还携带作为取代基的最多5个羟基,甲酰基,C1至C4烷氧基,苯氧基或C1 - 承载一个至C4烷氧基羰基和可被最多5个不相邻的氧原子,或下式的烷氧基化物基团被中断 - (CH 2)CO(A <1> O)间 - (甲<2> O)N - ÿ 是,表示其中A <1>和A <2>独立地表示1,2-亚烷基基团的碳原子数为2〜4,Y是氢,C 1至C 12表示烷基,苯基或C1-C4烷氧羰基并且k 数字1,2或3,且m和n各自为从0到50,其中m的+ n之和必须至少是4,亚氨基二乙腈与通式R-CHO的醛和HCN或碱金属氰化物反应,则 方法a),而不使用有机溶剂的和在路易斯存在 或布朗斯台德酸,或者b))的使用或不使用有机溶剂的和在1至40巴,使用或不使用有机溶剂的和在乳化剂,或c的存在的范围内的压力下进行。