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1. 发明授权

EP2779864B1 A CLEANING DEVICE 有权
公开(公告)号：EP2779864B1
公开(公告)日：2016-04-20
申请号：EP12849686.6
申请日：2012-09-25
申请人： O'Neill, Luke
发明人： O'Neill, Luke
IPC分类号： A45D27/46 , A46B13/00 , A46B11/06
CPC分类号： A45D27/46 , A46B11/06 , A46B13/005

2. 发明公开

EP2779864A1 A CLEANING DEVICE 有权
标题翻译：清洁装置
公开(公告)号：EP2779864A1
公开(公告)日：2014-09-24
申请号：EP12849686.6
申请日：2012-09-25
申请人： O'Neill, Luke
发明人： O'Neill, Luke
IPC分类号： A45D27/46
CPC分类号： A45D27/46 , A46B11/06 , A46B13/005
摘要： A cleaning device (1) for a safety razor having single or multiple parallel blades is disclosed. A hollow connector (5) is affixed to a water tap of a bathroom sink allowing water to flow therethrough into a body (2) depending from the connector (5), rotating a brush (15) held in the body (2) and exiting through a slot (14) in the body (2). The shaving head of the razor is positioned within the slot (14) such that the blades within the head are embedded within the bristles of the brush (15). As the brush (15) rotates, its bristles remove shaving debris from between the blades and immediate surrounds. After use, the device (1) can easily be disassembled to facilitate cleaning of all components thereof.
摘要翻译：公开了一种用于具有单个或多个平行刀片的安全剃刀的清洁装置（1）。中空连接器（5）固定到浴室水槽的水龙头上，允许水从中流过到连接器（5）下方的本体（2）中，旋转保持在本体（2）中的刷子（15）并退出穿过主体（2）中的狭槽（14）。剃刀的剃须头定位在狭槽（14）内，使得头部内的刀片嵌入刷子（15）的刷毛内。当刷子（15）旋转时，其刷毛从刀片和直接围绕之间移除剃屑。使用后，装置（1）可以容易地拆卸以便于清洁其所有部件。

3. 发明公开

EP2779864A4 A CLEANING DEVICE 有权
公开(公告)号：EP2779864A4
公开(公告)日：2015-07-15
申请号：EP12849686
申请日：2012-09-25
申请人： O'NEILL LUKE
发明人： O'NEILL LUKE
IPC分类号： A45D27/46 , A46B11/06 , A46B13/00
CPC分类号： A45D27/46 , A46B11/06 , A46B13/005

4. 发明专利

AU2011253740A1 A cleaning device 未知
公开(公告)号：AU2011253740A1
公开(公告)日：2013-06-06
申请号：AU2011253740
申请日：2011-11-17
申请人： O'NEILL LUKE
发明人： O'NEILL LUKE
IPC分类号： B26B21/40
摘要： A cleaning device (1) for a safety razor having single or multiple parallel blades is disclosed. A hollow connector (5) is affixed to a water tap of a bathroom sink allowing water to flow therethrough into a body (2) depending from the 5 connector (5), rotating a brush (15) held in the body (2) and exiting through a slot (14) in the body (2). The shaving head of the razor is positioned within the slot (14) such that the blades within the head are embedded within the bristles of the brush (15). As the brush (15) rotates, its bristles remove shaving debris from between the blades and immediate surrounds. After use, the device (1) 10 can easily be disassembled to facilitate cleaning of all components thereof .-6 Ac-

5. 发明专利

CA2853843A1 A CLEANING DEVICE 未知
公开(公告)号：CA2853843A1
公开(公告)日：2013-05-23
申请号：CA2853843
申请日：2012-09-25
申请人： O'NEILL LUKE
发明人： O'NEILL LUKE
IPC分类号： A45D27/46
摘要： A cleaning device (1) for a safety razor having single or multiple parallel blades is disclosed. A hollow connector (5) is affixed to a water tap of a bathroom sink allowing water to flow therethrough into a body (2) depending from the connector (5), rotating a brush (15) held in the body (2) and exiting through a slot (14) in the body (2). The shaving head of the razor is positioned within the slot (14) such that the blades within the head are embedded within the bristles of the brush (15). As the brush (15) rotates, its bristles remove shaving debris from between the blades and immediate surrounds. After use, the device (1) can easily be disassembled to facilitate cleaning of all components thereof.

6. 发明申请

WO2013071334A1 A CLEANING DEVICE 审中-公开
标题翻译：清洁装置
公开(公告)号：WO2013071334A1
公开(公告)日：2013-05-23
申请号：PCT/AU2012/001155
申请日：2012-09-25
申请人： O'NEILL, Luke
发明人： O'NEILL, Luke
IPC分类号： A45D27/46
CPC分类号： A45D27/46 , A46B11/06 , A46B13/005
摘要： A cleaning device (1) for a safety razor having single or multiple parallel blades is disclosed. A hollow connector (5) is affixed to a water tap of a bathroom sink allowing water to flow therethrough into a body (2) depending from the connector (5), rotating a brush (15) held in the body (2) and exiting through a slot (14) in the body (2). The shaving head of the razor is positioned within the slot (14) such that the blades within the head are embedded within the bristles of the brush (15). As the brush (15) rotates, its bristles remove shaving debris from between the blades and immediate surrounds. After use, the device (1) can easily be disassembled to facilitate cleaning of all components thereof.
摘要翻译：公开了一种具有单个或多个平行叶片的安全剃刀的清洁装置（1）。中空连接器（5）固定在卫生间水槽的水龙头上，允许水从连接器（5）流过其中进入主体（2），旋转保持在主体（2）中的刷子（15）并退出通过主体（2）中的狭槽（14）。剃刀的剃须刀头位于槽（14）内，使得头部内的刀片嵌入刷子（15）的刷毛内。当刷子（15）旋转时，其刷毛从叶片和直接环绕之间移除剃屑。使用后，可以容易地拆卸装置（1），以便于清洁其所有部件。

7. 发明申请

WO2010031801A2 COMPOSITION AND METHODS FOR MODULATING TOLL-LIKE RECEPTOR ACTIVITY 审中-公开
标题翻译：调节TOLL样受体活性的组合物和方法
公开(公告)号：WO2010031801A2
公开(公告)日：2010-03-25
申请号：PCT/EP2009062033
申请日：2009-09-16
申请人： TRINITY COLLEGE DUBLIN , O'NEILL LUKE ANTHONY JOHN , CARPENTER SUSAN
发明人： O'NEILL LUKE ANTHONY JOHN , CARPENTER SUSAN
IPC分类号： A61K38/17 , A61K31/00 , A61P31/00
CPC分类号： A61K38/1709 , A61K38/177 , C12N15/1138 , C12N2310/14 , G01N33/5041 , G01N33/6896 , G01N2500/10 , G01N2800/26 , G01N2800/28
摘要： The present invention relates to compositions and methods for use in the treatment of conditions such as septicaemia and septic shock. The invention further provides compositions and methods for the suppression of Toll-like Receptor 14 interaction with CD14 during Toll-like Receptor mediated signalling. The invention further provides screening assays to identify compounds which have utility in preventing the association of Toll-like Receptor 14 and CD14.
摘要翻译：本发明涉及用于治疗诸如败血症和感染性休克等病症的组合物和方法。本发明进一步提供了在Toll样受体介导的信号传导过程中抑制Toll样受体14与CD14相互作用的组合物和方法。本发明进一步提供筛选试验以鉴定在防止Toll样受体14和CD14的缔合中有用的化合物。

8. 发明申请

WO2009004094A3 COMPOUNDS AND METHODS FOR THE TREATMENT OF RENAL DISEASE 审中-公开
标题翻译：用于治疗肾病的化合物和方法
公开(公告)号：WO2009004094A3
公开(公告)日：2009-04-09
申请号：PCT/EP2008058732
申请日：2008-07-04
申请人： OPSONA THERAPEUTICS LTD , HEFFERNAN MARK , O'NEILL LUKE , MCGUIRK PETER , KEOGH BRIAN , LOCHER CHRISTOPHER
发明人： HEFFERNAN MARK , O'NEILL LUKE , MCGUIRK PETER , KEOGH BRIAN , LOCHER CHRISTOPHER
IPC分类号： A61K39/395 , A61K38/17 , A61P37/06 , C07K14/705
CPC分类号： C07K16/2896 , A61K38/00 , A61K45/06 , A61K2039/505 , C07K14/70596 , G01N2500/02
摘要： The present invention provides compounds and methods for the treatment and prophylaxis of renal disease and inflammation. In particular the invention provides methods for the treatment of kidney disease and failure through the administration of compounds which function as inhibitors of TLR2 function and expression.
摘要翻译：本发明提供了治疗和预防肾脏疾病和炎症的化合物和方法。特别地，本发明提供了通过施用作为TLR2功能和表达抑制剂的化合物来治疗肾脏疾病和失败的方法。

9. 发明申请

WO2009019260A2 COMPOSITION AND METHOD FOR TREATMENT OF REPERFUSION INJURY AND TISSUE DAMAGE 审中-公开
标题翻译：用于治疗再灌注损伤和组织损伤的组合物和方法
公开(公告)号：WO2009019260A2
公开(公告)日：2009-02-12
申请号：PCT/EP2008/060249
申请日：2008-08-04
申请人： OPSONA THERAPEUTICS LIMITED , HEFFERNAN, Mark , O'NEILL, Luke , McGUIRK, Peter , KEOGH, Brian , LOCHER, Christopher , DE KLEIJN, Dominique , ARSLAN, Fatih , PASTERKAMP, Gerard
发明人： HEFFERNAN, Mark , O'NEILL, Luke , McGUIRK, Peter , KEOGH, Brian , LOCHER, Christopher , DE KLEIJN, Dominique , ARSLAN, Fatih , PASTERKAMP, Gerard
IPC分类号： C12N15/113
CPC分类号： A61K39/3955 , A61K31/00 , A61K31/7088 , A61K38/177 , A61K45/06 , A61K2039/505 , C07K16/28 , C07K16/2803 , C07K16/2896 , C07K2317/76 , C12N15/1138 , G01N33/567 , G01N2500/00 , A61K2300/00
摘要： The present invention provides compounds and methods for the treatment and prophylaxis of ischemia reperfusion injury. In particular the invention provides compounds which function to suppress Toll-like Receptor 2 biological function or expression.
摘要翻译：本发明提供了治疗和预防缺血再灌注损伤的化合物和方法。特别地，本发明提供了用于抑制Toll样受体2生物学功能或表达的化合物。

10. 发明申请

WO2006111946A2 POLYPEPTIDES AND USE THEREOF 审中-公开
标题翻译：多聚物及其用途
公开(公告)号：WO2006111946A2
公开(公告)日：2006-10-26
申请号：PCT/IE2006/000037
申请日：2006-04-18
申请人： THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN , O'NEILL, Luke, Anthony, John , DUNNE, Aisling
发明人： O'NEILL, Luke, Anthony, John , DUNNE, Aisling
IPC分类号： C07K14/705 , A61K38/00
CPC分类号： C07K14/705 , A61K38/00 , C07K16/2896 , C07K2317/34 , G01N33/6872
摘要： An isolated polypeptide comprises an amino acid sequence of SEQ ID No. 1 or 2 or a variant or fragment thereof. The variant may comprise an amino acid sequence that is at least 70% or 95% identical to the amino acid sequence of SEQ ID No. 1 or 2. A fragment thereof may be a peptide comprising at least 12 contiguous amino acids of SEQ ID No. 1 or 2. The polypeptide exhibits toll-like receptor activity. The TLR has been named TLRl 4. TLR receptors recognise a range of ligands and activate a series of signalling pathways that lead to the induction of immune and inflammatory genes.
摘要翻译：分离的多肽包含SEQ ID No.1或2的氨基酸序列或其变体或片段。该变体可以包含与SEQ ID No.1或2的氨基酸序列至少70％或95％相同的氨基酸序列。其片段可以是包含SEQ ID No：No的至少12个连续氨基酸的肽该多肽表现出类似的收获活性。 TLR被命名为TLR1.4。TLR受体识别一系列配体并激活导致免疫和炎症基因诱导的一系列信号通路。

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