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1. 外观设计

USD254687S Biochemical card for use with an automated microbial identification machine 失效
公开(公告)号：USD254687S
公开(公告)日：1980-04-08
申请号：US6448
申请日：1979-01-25
申请人： Norman L. Fadler , Jack R. Kirchner , Paul W. Jones
设计人： Norman L. Fadler , Jack R. Kirchner , Paul W. Jones

2. 发明授权

US4038151A Card for use in an automated microbial detection system 失效
标题翻译：用于自动微生物检测系统的卡片
公开(公告)号：US4038151A
公开(公告)日：1977-07-26
申请号：US709611
申请日：1976-07-29
申请人： Norman L. Fadler , Paul W. Jones , Jack R. Kirchner
发明人： Norman L. Fadler , Paul W. Jones , Jack R. Kirchner
IPC分类号： B01L3/00 , C12M1/34 , G01N35/00 , C12K1/10
CPC分类号： B01L3/545 , C12M41/36 , G01N2035/00148
摘要： Improved cards for use in an automated machine to detect the presence of specific microbes and thereby identify them, enumerate them, and/or determine their susceptibility to antibiotics. Each card includes a plate having conical detection wells each with a selected medium therein, at least one filling port with a septum which is retained by a collar formed therein, and filler passages of specific length and configuration connecting the port to the wells. Discontinuities are provided in the filler passages to prevent unwanted fluid flow and to reduce migration of the microbes when the card is in use. Overflow chambers of a specific configuration are also provided adjacent the wells to entrap bubbles.

3. 发明授权

US4018652A Process and apparatus for ascertaining the concentration of microorganism in a water specimen 失效
标题翻译：确定水样中微生物浓度的方法和装置
公开(公告)号：US4018652A
公开(公告)日：1977-04-19
申请号：US647802
申请日：1976-01-09
申请人： James W. Lanham , James T. Holen , Norman L. Fadler
发明人： James W. Lanham , James T. Holen , Norman L. Fadler
IPC分类号： C12M1/20 , G01N35/00 , C12K1/04
CPC分类号： C12M23/12 , C12M41/36 , G01N2035/00148 , Y10S435/822 , Y10S435/848 , Y10S435/852 , Y10S435/874 , Y10S435/885
摘要： The concentration of microorganisms in a known volume of a water specimen is ascertained by introducing the water specimen into a plurality of wells which have known volume and contain a nutrient medium. The mixture of water specimen and nutrient medium is incubated and the wells are observed for a change in the appearance thereof which indicates metabolic activity, that is, the existence of microorganisms in the wells. If all the wells change appearance, then it is known that the concentration exceeds a certain limit, that is, at least one cell per specific well volume. On the other hand, if none of the wells change, then it is most likely the concentration is less than one cell per total volume of specimen in the wells. A change in appearance of some but not all of the wells indicates a concentration between the foregoing limits, and this concentration is estimated by statistical evaluation based on proven statistical computations.
摘要翻译：通过将水样品引入具有已知体积并含有营养培养基的多个孔中来确定已知体积的水样品中微生物的浓度。孵育水样和营养培养基的混合物，观察孔的外观变化，其表示代谢活性，即孔中存在微生物。如果所有的孔改变外观，则已知浓度超过一定限度，即每个特定孔体积至少一个细胞。另一方面，如果没有孔改变，则井中样品总体积的浓度最有可能小于一个细胞。一些但不是所有的孔的外观变化表示在上述限制之间的浓度，并且该浓度通过基于经验证的统计计算的统计评估来估计。

4. 外观设计

USD243542S Antimicrobial susceptibility card for use with an automated microbial identification machine 失效
公开(公告)号：USD243542S
公开(公告)日：1977-03-01
申请号：US659682
申请日：1976-02-20
申请人： Norman L. Fadler , Paul W. Jones , Jack R. Kirchner
设计人： Norman L. Fadler , Paul W. Jones , Jack R. Kirchner

5. 发明授权

US3957583A Apparatus and process for determining the susceptibility of microorganisms to antibiotics 失效
标题翻译：用于确定微生物对抗生素敏感性的装置和方法
公开(公告)号：US3957583A
公开(公告)日：1976-05-18
申请号：US528840
申请日：1974-12-02
申请人： Sandra F. Gibson , Norman L. Fadler
发明人： Sandra F. Gibson , Norman L. Fadler
IPC分类号： C12M1/18 , G01N35/00 , C12K1/04
CPC分类号： C12M23/22 , C12M23/12 , C12M23/34 , C12M41/46 , C12M23/42 , G01N2035/00148 , Y10S435/849
摘要： A process for determining the susceptibility of microorganisms to antibiotics involves introducing a diluted specimen into discrete quantities of a selective culture medium which favors a specific microorganism in that the microorganism is sustained by the medium and when so sustained will change the optical characteristics of the medium. Only the specific microorganism will alter the optical characteristics. Some of the discrete quantities are blended with known antibiotics, while at least one is not. If the specimen contains the microorganisms favored by the selective medium, the optical characteristics of the discrete quantity of pure selective medium, that is the one without antibiotics, will change. If the antibiotics in any of the other discrete quantities are ineffective against the favored microorganisms, the optical characteristics of those quantities will likewise change. No change in the optical characteristics of a discrete quantity indicates that the favored microorganism is susceptible to the antibiotic in the quantity.
摘要翻译：用于确定微生物对抗生素的敏感性的方法包括将稀释的样品引入离散量的选择性培养基，所述选择性培养基有利于特异性微生物，因为微生物被培养基维持，并且当其持续时会改变培养基的光学特性。只有特定的微生物会改变光学特性。一些离散量与已知的抗生素混合，至少有一种不是。如果样品含有选择性培养基所喜爱的微生物，则离子量的纯选择培养基（即没有抗生素的）的光学特性将发生变化。如果任何其他离散量的抗生素对有利微生物无效，这些量的光学特性也将同样改变。离散量的光学特性没有变化，表明有利微生物对抗生素的数量很敏感。

6. 外观设计

USD243543S Urine screening card for use with an automated microbial identification machine 失效
公开(公告)号：USD243543S
公开(公告)日：1977-03-01
申请号：US659922
申请日：1976-02-20
申请人： Norman L. Fadler , Paul W. Jones , Jack R. Kirchner
设计人： Norman L. Fadler , Paul W. Jones , Jack R. Kirchner

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