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    • 1. 发明授权
    • Medicinal compositions for treatment of atrial fibrillation
    • 用于治疗房颤的药物组合物
    • US06506745B1
    • 2003-01-14
    • US09869428
    • 2001-06-28
    • Kazuo AisakaNaoya ImagawaHisato MiyaiSatoshi Ogawa
    • Kazuo AisakaNaoya ImagawaHisato MiyaiSatoshi Ogawa
    • A61K3155
    • C07D417/06
    • The present invention relates to a medical composition for atrial fibrillation treatment, comprising a compound represented by the following formula [I]: Formula [I] [wherein R1 represents a hydrogen atom or lower alkoxy group; R2 represents a hydrogen atom, lower alkoxy group or phenyl group (wherein the phenyl group may be substituted with 1 to 3 substituents selected from a group consisting of a hydroxides group and a lower alkoxy group), (wherein R3 represents an acyl group); X represents —CO— or —CH2—, and n represents an integer of 1 or 2.] The present invention also relates to a method of treating atrial fibrillation using said compound, and to the use of said compound for producing a medicine for atrial fibrillation treatment or salts thereof or prodrugs thereof.
    • 本发明涉及一种用于心房颤动治疗的医药组合物,其包含由下式[I]表示的化合物:式[I] [其中R 1表示氢原子或低级烷氧基; R2表示氢原子,低级烷氧基或苯基(其中苯基可被1〜3个选自氢氧基和低级烷氧基的取代基取代),(其中R3表示酰基)。 X表示-CO-或-CH2-,n表示1或2的整数。]本发明还涉及使用所述化合物治疗心房颤动的方法,以及所述化合物在制备用于心房的药物中的用途 原纤维化处理或其盐或其前药。