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1. 发明授权

US09295650B2 Functional, cross-linked nanostructures for tandem optical imaging and therapy 有权
标题翻译：用于串联光学成像和治疗的功能性交联纳米结构
公开(公告)号：US09295650B2
公开(公告)日：2016-03-29
申请号：US13697149
申请日：2011-11-17
申请人： William L. Neumann , Richard B. Dorshow , John N. Freskos , Karen L. Wooley , Nam S. Lee , Yun Lin , Guorong Sun
发明人： William L. Neumann , Richard B. Dorshow , John N. Freskos , Karen L. Wooley , Nam S. Lee , Yun Lin , Guorong Sun
IPC分类号： A61K49/00 , A61K9/14 , A61K9/00 , A61K9/107 , A61K9/51 , A61K31/20 , A61K31/70 , A61K38/16 , A61K38/22 , A61K39/395 , A61M5/00
CPC分类号： A61K41/0057 , A61K9/0092 , A61K9/1075 , A61K9/146 , A61K9/5138 , A61K9/5192 , A61K31/20 , A61K31/337 , A61K31/351 , A61K31/70 , A61K31/704 , A61K38/08 , A61K38/16 , A61K38/22 , A61K45/06 , A61K47/6911 , A61K49/0021 , A61K49/0054 , A61K49/0082 , A61K49/0093 , A61M5/007 , A61K2300/00
摘要： The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for tandem optical imaging and therapy. Supramolecular structures and assemblies of the present invention include optically functional shell-cross linked micelles wherein optical functionality is achieved via incorporation of one or more linking groups that include one or more photoactive moieties. The present invention further includes imaging and therapeutic methods using one or more optical agents of the present invention including optically functional shell cross-linked micelles having an associated therapeutic agent.
摘要翻译：本发明提供包含光学功能交联的超分子结构和用于串联光学成像和治疗的组合物的光学剂。本发明的超分子结构和组件包括光学功能的壳交联胶束，其中通过引入一个或多个包含一个或多个光活性部分的连接基团来实现光学官能团。本发明还包括使用本发明的一种或多种光学剂的成像和治疗方法，其包括具有相关治疗剂的光学功能性壳交联胶束。

2. 发明授权

US5636912A Liquid crystal projector 失效
标题翻译：液晶投影仪
公开(公告)号：US5636912A
公开(公告)日：1997-06-10
申请号：US529073
申请日：1995-09-15
申请人： Nam S. Lee , Myung K. Yeo , Sang J. Lee , Joong I. Shin
发明人： Nam S. Lee , Myung K. Yeo , Sang J. Lee , Joong I. Shin
IPC分类号： G02F1/13 , G02B26/08 , G03B21/00 , H04N5/74 , G03B21/14
CPC分类号： H04N5/7441 , G02B26/0875
摘要： A liquid crystal projector for projecting an image on a screen includes a liquid crystal display (LCD) for displaying an image, a light source positioned behind the LCD for supplying light to project the image displayed on the LCD, a projection lens positioned in front of the LCD for focusing the light projected from the LCD onto the screen, and deflection means positioned between the LCD and the screen for deflecting the light focused through the projection lens to move the image position on the screen.
摘要翻译：一种用于在屏幕上投影图像的液晶投影仪包括用于显示图像的液晶显示器（LCD），位于LCD后面的光源，用于提供光以投影显示在LCD上的图像，投影透镜位于用于将从LCD投影的光聚焦到屏幕上的LCD以及位于LCD和屏幕之间的偏转装置，用于偏转通过投影透镜聚焦的光以移动屏幕上的图像位置。

3. 发明申请

US20150346099A1 Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH 审中-公开
标题翻译：用于监测pH的统一的，功能化的，交联的纳米结构
公开(公告)号：US20150346099A1
公开(公告)日：2015-12-03
申请号：US14721907
申请日：2015-05-26
申请人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
发明人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
IPC分类号： G01N21/64 , G01N33/84
CPC分类号： G01N21/6486 , A61B5/14539 , A61B5/1455 , A61K49/0021 , A61K49/0082 , A61K49/0093 , C08F8/00 , G01N21/75 , G01N33/582 , G01N33/84 , C08F293/005
摘要： Described herein are optical agents, including compositions, preparations and formulations, for monitoring the pH of a fluid. Optical agents described herein include photonic nanostructures and nanoassemblies including supramolecular structures, such as shell cross-linked micelles, that incorporate at least one linking group comprising one or more photoactive moieties that provide functionality as exogenous agents for a range of pH monitoring applications. Optical agents described herein comprise supramolecular structures having linking groups imparting useful optical and structural functionality. In an embodiment, for example, the presence of linking groups function to covalently cross link polymer components to provide a cross-linked shell stabilized supramolecular structure, and also impart useful optical functionality, for example by functioning as a fluorophore.
摘要翻译：本文描述的是用于监测流体pH值的光学剂，包括组合物，制剂和制剂。本文描述的光学剂包括光子纳米结构和纳米组件，其包括超分子结构，例如壳交联胶束，其结合至少一个连接基团，其包含一个或多个光活性部分，其提供作为一系列pH监测应用的外源性试剂的功能。本文所述的光学剂包括具有赋予有用的光学和结构功能性的连接基团的超分子结构。在一个实施方案中，例如，连接基团的存在用于共价交联聚合物组分以提供交联的壳稳定的超分子结构，并且还例如通过用作荧光团而赋予有用的光学官能团。

4. 发明申请

US20130210156A1 Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH 审中-公开
公开(公告)号：US20130210156A1
公开(公告)日：2013-08-15
申请号：US13697986
申请日：2011-05-13
申请人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
发明人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
IPC分类号： G01N21/75
CPC分类号： G01N21/6486 , A61B5/14539 , A61B5/1455 , A61K49/0021 , A61K49/0082 , A61K49/0093 , C08F8/00 , G01N21/75 , G01N33/582 , G01N33/84 , C08F293/005
摘要： Described herein are optical agents, including compositions, preparations and formulations, for monitoring the pH of a fluid. Optical agents described herein include photonic nanostructures and nanoassemblies including supramolecular structures, such as shell cross-linked micelles, that incorporate at least one linking group comprising one or more photoactive moieties that provide functionality as exogenous agents for a range of pH monitoring applications. Optical agents described herein comprise supramolecular structures having linking groups imparting useful optical and structural functionality. In an embodiment, for example, the presence of linking groups function to covalently cross link polymer components to provide a cross-linked shell stabilized supramolecular structure, and also impart useful optical functionality, for example by functioning as a fluorophore.

5. 发明授权

US4900081A Cover for a car with multiple use 失效
标题翻译：覆盖一辆多用途汽车
公开(公告)号：US4900081A
公开(公告)日：1990-02-13
申请号：US223159
申请日：1988-07-22
申请人： Nam S. Lee
发明人： Nam S. Lee
IPC分类号： B60J11/00
CPC分类号： B60J11/00
摘要： A multiple use cover for a car made of a plurality of individual truss modules flexibly connected with center pins, external pins and internal pins forming a scissors structure. Parallel major trusses are interconnected with transverse bars additionally used on the external pins of the some truss module. The external ends of both the flexible major trusses are coupled to fixing holes in a support beam with the use of fixing pins. The internal ends of the trusses are connected to elongate guide holes with the movable pins. The cover is connected to a height adjusting base and to a rotatable connecting frame. The rotatable connected frame is coupled to a fixing pillar which is fixed to the bottom of the trunk of a car.
摘要翻译：用于由多个单独的桁架模块制成的多重使用的盖子，其与中心销，外部销和形成剪刀结构的内部销弹性地连接。平行的主要桁架与一些桁架模块的外部引脚上另外使用的横向杆相互连接。两个柔性主桁架的外端通过使用固定销连接到支撑梁中的固定孔。桁架的内端与可动销连接成细长的导向孔。盖子连接到高度调节底座和可旋转的连接框架。可旋转连接的框架联接到固定柱，该固定柱固定到汽车的行李箱的底部。

6. 发明申请

US20180335385A1 Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH 审中-公开
公开(公告)号：US20180335385A1
公开(公告)日：2018-11-22
申请号：US15902759
申请日：2018-02-22
申请人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
发明人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
IPC分类号： G01N21/64 , G01N21/75 , G01N33/84 , C08F8/00 , A61B5/145 , G01N33/58 , A61K49/00 , A61B5/1455 , C08F293/00
CPC分类号： G01N21/6486 , A61B5/14539 , A61B5/1455 , A61K49/0021 , A61K49/0082 , A61K49/0093 , C08F8/00 , G01N21/75 , G01N33/582 , G01N33/84 , C08F293/005
摘要： Fluorescence methods and systems that use an optical agent for measuring the pH of a fluid. The optical agent is a photonic nanostructure having a supramolecular structure, such as a shell cross-linked micelle that incorporates at least one linking group that includes one or more photoactive moieties.

7. 发明授权

US5483285A Movie camera system having view finding and projecting operations and method 失效
标题翻译：具有查看和投影操作和方法的电影摄像机系统
公开(公告)号：US5483285A
公开(公告)日：1996-01-09
申请号：US47440
申请日：1993-04-16
申请人： Jae C. Lim , Myung K. Yeo , Yong T. Lim , Nam S. Lee , Jin W. Seo , Dae S. Shim
发明人： Jae C. Lim , Myung K. Yeo , Yong T. Lim , Nam S. Lee , Jin W. Seo , Dae S. Shim
IPC分类号： H04N5/225 , H04N5/232 , H04N5/74 , H04N5/30
CPC分类号： G03B17/54 , H04N5/23293 , H04N5/7441 , H04N9/3176
摘要： A move camera system having a function for projecting an image of an object being presently or previously imaged on an external screen, as well as a function for monitoring the image and a method of displaying a video signal therein. A composite video signal from a camera section or a VCR section is processed by a video signal processor in a display section so that be displayed on a display device including a matrix of pixels. The processed video signal from the video signal processor includes red, green and blue color signals. Arrangement of the proposed video signal is changed according to whether the projecting junction of the view finding function is selected. According to the selected function, an optical image resulting from the video signal displayed on the display device is lighted by a large or small amount of light from a light source at the rear. The user can view or monitor the image on the display device through a focus lens unit at a front portion thereof. The image on the display device is also projected on an external screen by a large amount of light from the light source. A memory may be used to change the arrangement of the video signal before application to the display section. In this case, the display section functions only to sequentially display the video signals therein.
摘要翻译：一种移动式摄像机系统，其具有用于投影当前或先前在外部屏幕上成像的对象的图像的功能，以及用于监视图像的功能以及在其中显示视频信号的方法。来自相机部分或VCR部分的复合视频信号由显示部分中的视频信号处理器处理，以便显示在包括像素矩阵的显示装置上。来自视频信号处理器的经处理的视频信号包括红色，绿色和蓝色信号。所提出的视频信号的布置根据是否选择了查看功能的投影结而改变。根据所选择的功能，从显示装置上显示的视频信号产生的光学图像被来自后方的光源的大量或少量的光点亮。用户可以通过其前部的聚焦透镜单元来观看或监视显示设备上的图像。显示装置上的图像也通过来自光源的大量光投射在外部屏幕上。可以使用存储器来在施加到显示部分之前改变视频信号的布置。在这种情况下，显示部分仅用于顺序地显示其中的视频信号。

8. 发明申请

US20190302026A1 Uniform, Functionalized, Cross-Linked Nanostructures for Monitoring pH 审中-公开
公开(公告)号：US20190302026A1
公开(公告)日：2019-10-03
申请号：US16381988
申请日：2019-04-11
申请人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
发明人： Karen L. Wooley , Richard B. Dorshow , John N. Freskos , William L. Neumann , Jeng J. Shieh , Nam S. Lee , Yun Lin , Guorong Sun
IPC分类号： G01N21/64 , G01N21/75 , G01N33/84 , G01N33/58 , C08F8/00 , A61B5/145 , A61K49/00 , A61B5/1455
摘要： Fluorescence methods and systems that use an optical agent for measuring the pH of a fluid. The optical agent is a photonic nanostructure having a supramolecular structure, such as a shell cross-linked micelle that incorporates at least one linking group that includes one or more photoactive moieties.

9. 发明申请

US20130137976A1 Functional, Cross-Linked Nanostructures for Tandem Optical Imaging and Therapy 有权
标题翻译：功能，交联纳米结构的串联光学成像和治疗
公开(公告)号：US20130137976A1
公开(公告)日：2013-05-30
申请号：US13697149
申请日：2011-11-17
申请人： William L. Neumann , Richard B. Dorshow , John N. Freskos , Karen L. Wooley , Nam S. Lee , Lily Nun Lin , Guorong Sun
发明人： William L. Neumann , Richard B. Dorshow , John N. Freskos , Karen L. Wooley , Nam S. Lee , Lily Nun Lin , Guorong Sun
IPC分类号： A61K9/14 , A61K39/395 , A61M5/00 , A61K38/22 , A61K31/20 , A61K38/16 , A61K31/70
CPC分类号： A61K41/0057 , A61K9/0092 , A61K9/1075 , A61K9/146 , A61K9/5138 , A61K9/5192 , A61K31/20 , A61K31/337 , A61K31/351 , A61K31/70 , A61K31/704 , A61K38/08 , A61K38/16 , A61K38/22 , A61K45/06 , A61K47/6911 , A61K49/0021 , A61K49/0054 , A61K49/0082 , A61K49/0093 , A61M5/007 , A61K2300/00
摘要： The present invention provides optical agents comprising optically functional cross linked supramolecular structures and assemblies useful for tandem optical imaging and therapy. Supramolecular structures and assemblies of the present invention include optically functional shell-cross linked micelles wherein optical functionality is achieved via incorporation of one or more linking groups that include one or more photoactive moieties. The present invention further includes imaging and therapeutic methods using one or more optical agents of the present invention including optically functional shell cross-linked micelles having an associated therapeutic agent.
摘要翻译：本发明提供包含光学功能交联的超分子结构和用于串联光学成像和治疗的组合物的光学剂。本发明的超分子结构和组件包括光学功能的壳交联胶束，其中通过引入一个或多个包含一个或多个光活性部分的连接基团来实现光学官能团。本发明还包括使用本发明的一种或多种光学剂的成像和治疗方法，其包括具有相关治疗剂的光学功能性壳交联胶束。

10. 发明授权

US5300976A Movie camera system having view finding and projecting operations 失效
标题翻译：电影摄像机系统具有查找和投影操作
公开(公告)号：US5300976A
公开(公告)日：1994-04-05
申请号：US47442
申请日：1993-04-16
申请人： Jae C. Lim , Myung K. Yeo , Yong T. Lim , Nam S. Lee , Jin W. Seo , Dae S. Shim
发明人： Jae C. Lim , Myung K. Yeo , Yong T. Lim , Nam S. Lee , Jin W. Seo , Dae S. Shim
IPC分类号： H04N5/225 , H04N5/232 , H04N5/74 , H04N9/31 , G03B13/02 , H04N5/30
CPC分类号： G03B17/48 , H04N5/23293 , H04N5/7441 , H04N9/3176
摘要： An electronic movie camera system having a projecting function as well as a view finding function. The system includes a system body, a housing mounted on the system body, an LCD panel disposed within the housing to display an image corresponding to an image signal received from the system body, a focusing lens unit mounted to one end of the housing disposed rearwardly of the LCD panel and adapted to project the displayed image on an external screen, a back light disposed rearwardly of the LCD panel to emit a view finding light, a polarizing plate disposed forwardly of the LCD panel, a view finder coupling unit selectively attached to the other end of the housing disposed forwardly of the LCD panel, the view finder coupling unit having an eye lens, and a projector coupling unit selectively attached to the other end of the housing, the projector coupling unit having a light source for emitting a projecting light and a condensing lens for the projecting light, whereby the movie camera system is capable of both a view finding operation and a projecting operation.
摘要翻译：一种具有投影功能的电子摄像机系统以及观察功能。该系统包括系统主体，安装在系统主体上的壳体，设置在壳体内以显示与从系统主体接收到的图像信号相对应的图像的LCD面板;安装在向后设置的壳体的一端的聚焦透镜单元并且适于将所显示的图像投影到外部屏幕上，背面设置在LCD面板的后方以发出查找光，设置在LCD面板的前方的偏振片，选择性地连接到所述壳体的另一端设置在所述LCD面板的前方，所述取景器联接单元具有眼睛透镜，以及选择性地附接到所述外壳的另一端的投影仪联接单元，所述投影仪联接单元具有用于发射突出光和用于投射光的聚光透镜，由此电影摄影系统能够进行查看操作和投影操作。

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