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1. 发明公开

EP3215124A1 COMPOSITION AND METHOD FOR RELIEVING PAIN AND INFLAMMATION, TREATMENT OF ERECTILE DYSFUNCTION, AND TREATMENT OF ACNE 无效
标题翻译：消除疼痛和炎症的组合物和方法，治疗搔痒症和治疗痤疮
公开(公告)号：EP3215124A1
公开(公告)日：2017-09-13
申请号：EP15857120.8
申请日：2015-11-05
申请人： Nordquist, Robert E. , Rosacker, James A. , Downes, Patrick J. , Chen, Wei R.
发明人： Nordquist, Robert E. , Rosacker, James A. , Downes, Patrick J. , Chen, Wei R.
IPC分类号： A61K9/00 , A61K9/06 , A61K31/00
CPC分类号： A61K47/36 , A61K9/0014 , A61K9/0034 , A61K9/06 , A61K31/045 , A61K31/10 , A61K31/16 , A61K31/167 , A61K31/192 , A61K31/407 , A61K31/445 , A61K31/451 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/60 , A61K31/722 , A61K45/06 , A61K47/10 , A61K47/20 , A61K2300/00
摘要： Transdermal compositions including chitosan, glycated chitosan, or a combination thereof are provided for use in treatment methods wherein the compositions are externally applied for relieving pain and inflammation, treating erectile dysfunction, treating acne, causing hair growth, and for veterinary treatment of animals for relieving pain and inflammation.
摘要翻译：经皮组合物，包括脱乙酰壳多糖，糖化壳聚糖，或提供了用于在治疗方法中的用途，其中所述组合物被外部施加的用于缓解疼痛和炎症，治疗勃起功能障碍，治疗痤疮，引起毛发生长它们的组合，以及用于缓解兽医治疗动物的疼痛和炎症。

2. 发明专利

IL233649A Chitosan-derived compositions 未知
公开(公告)号：IL233649A
公开(公告)日：2019-07-31
申请号：IL23364914
申请日：2014-07-15
申请人： IMMUNOPHOTONICS INC , CHEN WEI , HODE TOMAS , CARUBELLI RAOUL , WAYNANT KRISTOPHER , NORDQUIST ROBERT , ALLERUZZO LUCIANO , RAKER JOSEPH , JENKINS PETER
发明人： CHEN WEI , HODE TOMAS , CARUBELLI RAOUL , WAYNANT KRISTOPHER , NORDQUIST ROBERT , ALLERUZZO LUCIANO , RAKER JOSEPH , JENKINS PETER
IPC分类号： A61K31/722 , A61B18/20 , A61K39/00 , A61K39/39 , A61K39/395 , A61K41/00 , C08B37/08
摘要： The present invention relates to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.

3. 发明专利

IL233649D0 Chitosan-derived compositions 未知
公开(公告)号：IL233649D0
公开(公告)日：2014-08-31
申请号：IL23364914
申请日：2014-07-15
申请人： IMMUNOPHOTONICS INC , CHEN WEI , HODE TOMAS , CARUBELLI RAOUL , WAYNANT KRISTOPHER , NORDQUIST ROBERT , ALLERUZZO LUCIANO , RAKER JOSEPH , JENKINS PETER
IPC分类号： A61K20060101
摘要： The present invention relates to therapeutic compositions comprising chitosan-derived compositions used in connection with methods for treating neoplasms, such as for instance, malignant lung, thyroid and kidney neoplasms, and other types of malignant neoplasms, and other medical disorders.

4. 发明申请

WO2004056294A1 DEVICE FOR OCULAR AQUEOUS DRAINAGE 审中-公开
标题翻译： OCULAR AQUEOUS DRAINAGE设备
公开(公告)号：WO2004056294A1
公开(公告)日：2004-07-08
申请号：PCT/EP2003/014532
申请日：2003-12-18
申请人： NOVARTIS AG , NOVARTIS PHARMA GMBH , LISK, James, Reid, Jr. , MEMMEN, James, E. , HAMPTON, Scott , NORDQUIST, Robert, E. , ROBLEDO, Phillip, Vincent , TAI, Kok-Ming
发明人： LISK, James, Reid, Jr. , MEMMEN, James, E. , HAMPTON, Scott , NORDQUIST, Robert, E. , ROBLEDO, Phillip, Vincent , TAI, Kok-Ming
IPC分类号： A61F9/007
CPC分类号： A61F9/00781
摘要： An ophthalmic implant having a body for positioning in a recess created in the sclera, feet for positioning in the anterior chamber, and a neck between the body and the feet for positioning in a scleral opening created between the scleral recess and the anterior chamber. The implant feet extend beyond the implant body and have a curvature approximating the curvature of the anterior chamber. The implant has drainage passageways for draining ocular fluid from the anterior chamber. The passageways are formed in outer surfaces or through the interior of the implant. Interior passageways are formed in surfaces of layers of the implant or by voids in inner layers of the implant. Related methods include creating undercuts that receive outer portions of the implant body and creating a scleral opening that is longer than the implant neck.
摘要翻译：一种眼科植入物，其具有用于定位在形成于巩膜中的凹部中的主体，用于定位在前房中的脚，以及在身体和脚之间的颈部，用于定位在巩膜凹部和前房之间产生的巩膜开口中。植入物脚延伸超过植入体，并具有接近前房曲率的曲率。植入物具有用于从前房排出眼液的排水通道。通道形成在外表面或通过植入物的内部。内部通道形成在植入物的层的表面中或通过植入物的内层中的空隙形成。相关方法包括产生接收植入物主体的外部部分的底切部分，并产生比植入物颈部更长的巩膜开口。

5. 发明申请

WO02102454A3 APPARATUS AND METHOD FOR DELIVERY OF LASER LIGHT 审中-公开
标题翻译：用于交付激光的装置和方法
公开(公告)号：WO02102454A3
公开(公告)日：2003-03-27
申请号：PCT/US0204173
申请日：2002-02-12
申请人： NORDQUIST ROBERT E
发明人： NORDQUIST ROBERT E
IPC分类号： A61B17/00 , A61B18/20 , A61N5/06 , A61N5/067
CPC分类号： A61N5/0616 , A61B2017/00199 , A61B2018/2065 , A61N2005/0644 , A61N2005/0652 , A61N2005/0663 , A61N2005/067
摘要： An apparatus for the delivery of laser light in a therapeutic environment including: a console; an optical waveguide wherein a first end of the waveguide is configured to expose a biological tissue to energy transmitted through the waveguide; a plurality of laser diodes housed within the console such that the light emitted by each of the diodes will illuminate a second end of the optical wave guide; and a power supply for providing electrical power to each laser diode. Preferably each laser diode is configured to produce a unique wavelength of light. The power supply provides an independently controllable output for each laser such that the exposure, both in terms of intensity and duration, to each wavelength of light may be controlled independently of the exposure to each of the other wavelengths of light.
摘要翻译：一种用于在治疗环境中传送激光的装置，包括：控制台; 光波导，其中波导的第一端被配置为将生物组织暴露于通过波导传输的能量; 容纳在控制台内的多个激光二极管，使得由每个二极管发出的光将照亮光波导的第二端; 以及用于向每个激光二极管提供电力的电源。优选地，每个激光二极管被配置为产生独特的波长的光。电源为每个激光器提供独立可控的输出，使得可以独立于对每个其它波长的光的曝光来控制对光波长的强度和持续时间的曝光。

6. 发明专利

AU2002329169A1 Apparatus and method for delivery of laser light 未知
公开(公告)号：AU2002329169A1
公开(公告)日：2003-01-02
申请号：AU2002329169
申请日：2002-02-12
申请人： NORDQUIST ROBERT E
发明人： NORDQUIST ROBERT E
IPC分类号： A61B17/00 , A61B18/20 , A61N5/06 , A61N5/067
摘要： An apparatus for the delivery of laser light in a therapeutic environment including: a console; an optical waveguide wherein a first end of the waveguide is configured to expose a biological tissue to energy transmitted through the waveguide; a plurality of laser diodes housed within the console such that the light emitted by each of the diodes will illuminate a second end of the optical wave guide; and a power supply for providing electrical power to each laser diode. Preferably each laser diode is configured to produce a unique wavelength of light. The power supply provides an independently controllable output for each laser such that the exposure, both in terms of intensity and duration, to each wavelength of light may be controlled independently of the exposure to each of the other wavelengths of light.

7. 发明公开

EP3215124A4 COMPOSITION AND METHOD FOR RELIEVING PAIN AND INFLAMMATION, TREATMENT OF ERECTILE DYSFUNCTION, AND TREATMENT OF ACNE 无效
公开(公告)号：EP3215124A4
公开(公告)日：2018-07-11
申请号：EP15857120
申请日：2015-11-05
申请人： NORDQUIST ROBERT E , ROSACKER JAMES A , DOWNES PATRICK J , CHEN WEI R
发明人： NORDQUIST ROBERT E , ROSACKER JAMES A , DOWNES PATRICK J , CHEN WEI R
IPC分类号： A61K9/00 , A61K9/06 , A61K31/00 , A61K31/10 , A61K31/167 , A61K31/407 , A61K31/445 , A61K31/506 , A61K31/519 , A61K31/60 , A61K47/10 , A61K47/20 , A61K47/36
CPC分类号： A61K47/36 , A61K9/0014 , A61K9/0034 , A61K9/06 , A61K31/045 , A61K31/10 , A61K31/16 , A61K31/167 , A61K31/192 , A61K31/407 , A61K31/445 , A61K31/451 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/60 , A61K31/722 , A61K45/06 , A61K47/10 , A61K47/20 , A61K2300/00
摘要： Transdermal compositions including chitosan, glycated chitosan, or a combination thereof are provided for use in treatment methods wherein the compositions are externally applied for relieving pain and inflammation, treating erectile dysfunction, treating acne, causing hair growth, and for veterinary treatment of animals for relieving pain and inflammation.

8. 发明申请

WO2020197578A1 SEMI-SYNTHETIC BIOPOLYMERS FOR USE IN STIMULATING THE IMMUNE SYSTEM 审中-公开
公开(公告)号：WO2020197578A1
公开(公告)日：2020-10-01
申请号：PCT/US2019/040292
申请日：2019-07-02
申请人： IMMUNOPHOTONICS, INC. , HODE, Tomas , LAM, Siu Kit , RAKER, Joseph , ALLERUZZO, Luciano , NORDQUIST, Robert
发明人： HODE, Tomas , LAM, Siu Kit , RAKER, Joseph , ALLERUZZO, Luciano , NORDQUIST, Robert
IPC分类号： A61K39/39 , A61K39/395
摘要： The present relates generally to a method for stimulating the activation of an antigen presenting cell. The method includes activating antigen presenting cells by contacting the cells with an effective amount of a GC polymer that has a molecular weight of less than 420 kDa, followed by determining whether the antigen presenting cells are activated by measuring the amount of co-stimulatory marker CD40 expressed by the cells. Also, the present relates to an injectable pharmaceutical composition for stimulating the activation of an antigen presenting cell.

9. 发明申请

WO2016073723A1 COMPOSITION AND METHOD FOR RELIEVING PAIN AND IFLAMMATION, TREATMENT OF ERECTILE DYSFUNCTION, AND TREATMENT OF ACNE 审中-公开
标题翻译：用于消除疼痛和肥胖的组合物和方法，治疗精神功能障碍和治疗ACNE
公开(公告)号：WO2016073723A1
公开(公告)日：2016-05-12
申请号：PCT/US2015/059247
申请日：2015-11-05
申请人： NORDQUIST, Robert, E. , ROSACKER, James, A. , DOWNES, Patrick, J.
发明人： NORDQUIST, Robert, E. , ROSACKER, James, A. , DOWNES, Patrick, J.
IPC分类号： A61K9/00 , A61K9/06 , A61K31/00
CPC分类号： A61K47/36 , A61K9/0014 , A61K9/0034 , A61K9/06 , A61K31/045 , A61K31/10 , A61K31/16 , A61K31/167 , A61K31/192 , A61K31/407 , A61K31/445 , A61K31/451 , A61K31/506 , A61K31/513 , A61K31/519 , A61K31/60 , A61K31/722 , A61K45/06 , A61K47/10 , A61K47/20 , A61K2300/00
摘要： Transdermal compositions including chitosan, glycated chitosan, or a combination thereof are provided for use in treatment methods wherein the compositions are externally applied for relieving pain and inflammation, treating erectile dysfunction, treating acne, causing hair growth, and for veterinary treatment of animals for relieving pain and inflammation.
摘要翻译：提供了包含壳聚糖，糖化壳聚糖或其组合的透皮组合物用于治疗方法，其中外部施用组合物以缓解疼痛和炎症，治疗勃起功能障碍，治疗痤疮，引起毛发生长和用于兽医治疗动物以减轻疼痛和炎症。

10. 发明申请

WO1996021406A1 METHOD AND APPARATUS FOR SURGICAL ABLATION OF THE CORNEA 审中-公开
标题翻译：角膜外科手术的方法和装置
公开(公告)号：WO1996021406A1
公开(公告)日：1996-07-18
申请号：PCT/US1995015181
申请日：1995-11-21
申请人： CORNEAL CONTOURING DEVELOPMENT, L.L.C. , KILMER, Lauren, G. , NORDQUIST, Robert, E. , NADALSKY, Michael , GIBSON, David, R.
发明人： CORNEAL CONTOURING DEVELOPMENT, L.L.C.
IPC分类号： A61F09/00
CPC分类号： A61F9/013 , Y10S977/904
摘要： Improved apparatus for surgically reprofiling the cornea to correct refractive error. A hand held assembly including a vacuum controlled fixation ring and adapter/sleeve assembly that is used as the initial set-up upon the cornea for supporting a micrometer adjusted surgical knife blade that can be manually or mechanically rotated or oscillated to correct the refractive error by ablation scraping or sculpting of the cornea. Video monitoring is provided. The apparatus also may be used in conjunction with other known refractive techniques to provide primary or secondary corneal reshaping, to finish or fine tune a known procedure, or to otherwise expand, smooth or enhance the anterior or stromal cornea.
摘要翻译：改进的手术重塑角膜的装置以矫正屈光不正。一种手持组件，其包括真空控制的固定环和适配器/套筒组件，其用作角膜上的初始设置，用于支撑测微计调节的手术刀片，其可以手动或机械地旋转或振荡以通过消融刮或雕刻角膜。提供视频监控。该装置还可以与其他已知的屈光技术结合使用，以提供原发性或次级角膜重塑，完成或微调已知的过程，或以其它方式扩展，平滑或增强前角质或基质角膜。

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