专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

US20200347397A1 Carbon Fixation Systems in Plants and Algae 审中-公开
公开(公告)号：US20200347397A1
公开(公告)日：2020-11-05
申请号：US16917028
申请日：2020-06-30
申请人： NMC, INC.
发明人： Richard Thomas Sayre , Somya S. Subramanian , Natalia Friedland
IPC分类号： C12N15/82 , C12P1/00 , C12N1/12 , C07K14/415
摘要： Provided are heterologous nucleic acid constructs, vectors and methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc.

2. 发明申请

US20190203222A1 Carbon Fixation Systems in Plants and Algae 审中-公开
公开(公告)号：US20190203222A1
公开(公告)日：2019-07-04
申请号：US16358331
申请日：2019-03-19
申请人： NMC, INC.
发明人： Richard Thomas Sayre , Somya S. Subramanian , Natalia Friedland
IPC分类号： C12N15/82 , C07K14/415 , C12N1/12 , C12P1/00
摘要： Provided are methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc.

3. 发明申请

US20230123612A1 Productivity and Bioproduct Formation in Phototropin Knock/Out Mutants in Microalgae 有权
公开(公告)号：US20230123612A1
公开(公告)日：2023-04-20
申请号：US17678834
申请日：2022-02-23
申请人： NMC, INC. , LOS ALAMOS NATIONAL SECURITY, LLC
发明人： Sangeeta Negi , Richard Thomas Sayre , Shawn Robert Starkenburg
IPC分类号： C12N9/12 , C07K14/405 , C12N1/12
摘要： Phototropin is a blue light receptor, which mediates a variety of blue-light elicited physiological processes in plants and algae. In higher plants these processes include phototropism, chloroplast movement and stomatal opening. In the green alga Chlamydomonas reinhardtii, phototropin plays a vital role in progression of the sexual life cycle and in the control of the eye spot size and light sensitivity Phototropin is also involved in blue-light mediated changes in the synthesis of chlorophylls, carotenoids, chlorophyll binding proteins. We compared the transcriptome of phototropin knock out (PHOT KO) mutant and wild-type parent to analyze differences in gene expression in high light grown cultures (500 µmol photons m-2s-1). Our results indicate the up-regulation of genes involved in photosynthetic electron transport chain, carbon fixation pathway, starch, lipid, and cell cycle control genes. With respect to photosynthetic electron transport genes, genes encoding proteins of the cytochrome b6f and ATP synthase complex were up regulated potentially facilitating proton-coupled electron transfer. In addition genes involved in limiting steps in the Calvin cycle Ribulose-1 ,5-bisphosphate carboxylase/oxygenase (RuBisCO), Sidoheptulose 1,7 bisphosphatase (SBPase), Glyceraldehyde-3-phosphate dehydrogenase (3PGDH) and that mediate cell-cycle control (CDK) were also up regulated along with starch synthase and fatty acid biosynthesis genes involved in starch and lipid synthesis. In addition, transmission electron micrographs show increased accumulation of starch granules in PHOT mutant compared to wild type, which is consistent with the higher expression of starch synthase genes. Collectively, the altered patterns of gene expression in the PHOT mutants were associated with a two-fold increase in growth and biomass accumulation compared to wild type when grown in environmental photobioreactors (Phenometrics) that simulate a pond environment. In conclusion, our studies suggest that phototropin may be a master gene regulator that suppresses rapid cell growth and promotes gametogenesis and sexual recombination in wild type strains.

4. 发明授权

US11001853B2 Carbon fixation systems in plants and algae 有权
公开(公告)号：US11001853B2
公开(公告)日：2021-05-11
申请号：US16917028
申请日：2020-06-30
申请人： NMC, INC.
发明人： Richard Thomas Sayre , Somya S. Subramanian , Natalia Friedland
IPC分类号： C12N15/82 , C12P1/00 , C12N1/12 , C07K14/415
摘要： Provided are heterologous nucleic acid constructs, vectors and methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc.

5. 发明授权

US10696977B2 Carbon fixation systems in plants and algae 有权
公开(公告)号：US10696977B2
公开(公告)日：2020-06-30
申请号：US16358331
申请日：2019-03-19
申请人： NMC, INC.
发明人： Richard Thomas Sayre , Somya S. Subramanian , Natalia Friedland
IPC分类号： C12N15/82 , C12P1/00 , C12N1/12 , C07K14/415
摘要： Provided are methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc.

6. 发明申请

US20180187170A1 Productivity and Bioproduct Formation in Phototropin Knock/Out Mutants in Microalgae 审中-公开
公开(公告)号：US20180187170A1
公开(公告)日：2018-07-05
申请号：US15831178
申请日：2017-12-04
申请人： NMC, INC. , LOS ALAMOS NATIONAL SECURITY, LLC
发明人： Sangeeta Negi , Richard Thomas Sayre , Shawn Robert Starkenburg
IPC分类号： C12N9/12 , C12N9/02 , C12N1/12 , C12N15/01 , C12N15/11 , C12N9/22 , C12P7/64 , C12P19/04 , C12P23/00
CPC分类号： C12N9/12 , C07K14/405 , C12N1/12 , C12N9/0051 , C12N9/1205 , C12N9/22 , C12N15/01 , C12N15/11 , C12N2310/20 , C12N2800/80 , C12P7/64 , C12P19/04 , C12P23/00 , C12Y108/01009 , C12Y207/11
摘要： Phototropin is a blue light receptor, which mediates a variety of blue-light elicited physiological processes in plants and algae. In higher plants these processes include phototropism, chloroplast movement and stomatal opening. In the green alga Chlamydomonas reinhardtii, phototropin plays a vital role in progression of the sexual life cycle and in the control of the eye spot size and light sensitivity Phototropin is also involved in blue-light mediated changes in the synthesis of chlorophylls, carotenoids, chlorophyll binding proteins. We compared the transcriptome of phototropin knock out (PHOT KO) mutant and wild-type parent to analyze differences in gene expression in high light grown cultures (500 μmol photons m−2 s−1). Our results indicate the up-regulation of genes involved in photosynthetic electron transport chain, carbon fixation pathway, starch, lipid, and cell cycle control genes. With respect to photosynthetic electron transport genes, genes encoding proteins of the cytochrome b6f and ATP synthase complex were up regulated potentially facilitating proton-coupled electron transfer. In addition genes involved in limiting steps in the Calvin cycle Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), Sidoheptulose 1,7 bisphosphatase (SBPase), Glyceraldehyde-3-phosphate dehydrogenase (3PGDH) and that mediate cell-cycle control (CDK) were also up regulated along with starch synthase and fatty acid biosynthesis genes involved in starch and lipid synthesis. In addition, transmission electron micrographs show increased accumulation of starch granules in PHOT mutant compared to wild type, which is consistent with the higher expression of starch synthase genes. Collectively, the altered patterns of gene expression in the PHOT mutants were associated with a two-fold increase in growth and biomass accumulation compared to wild type when grown in environmental photobioreactors (Phenometrics) that simulate a pond environment. In conclusion, our studies suggest that phototropin may be a master gene regulator that suppresses rapid cell growth and promotes gametogenesis and sexual recombination in wild type strains.

7. 发明授权

US11459578B2 Carbon fixation systems in plants and algae 有权
公开(公告)号：US11459578B2
公开(公告)日：2022-10-04
申请号：US17317362
申请日：2021-05-11
申请人： NMC, INC.
发明人： Richard Thomas Sayre , Somya S. Subramanian , Natalia Friedland
IPC分类号： C12N15/82 , C12P1/00 , C12N1/12 , C07K14/415
摘要： Provided are heterologous nucleic acid constructs, vectors and methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc.

8. 发明申请

US20210071190A1 TRANSGENIC PLANTS WITH ENGINEERED REDOX SENSITIVE MODULATION OF PHOTOSYNTHETIC ANTENNA COMPLEX PIGMENTS AND METHODS FOR MAKING THE SAME 有权
公开(公告)号：US20210071190A1
公开(公告)日：2021-03-11
申请号：US16995499
申请日：2020-08-17
申请人： NMC, INC.
发明人： Richard Thomas Sayre
IPC分类号： C12N15/82 , C12N9/02
摘要： Embodiments of the present invention provide for a transgenic plan, methods of making and DNA constructs for use in the transgenic plant which transgenic plant is capable of modulating its photosynthetic antenna complex composition in response to increases or decreases in light intensity by modulation of the ratio of chlorophyll a to chlorophyll b such that there is an increase in the Chl a/b ratio at high light intensity and a decrease in the Chl a/b ratio at low light intensity versus wild-type plants grown in the same conditions.

9. 发明申请

US20200208125A1 Productivity and Bioproduct Formation in Phototropin Knock/Out Mutants in Microalgae 审中-公开
公开(公告)号：US20200208125A1
公开(公告)日：2020-07-02
申请号：US16820062
申请日：2020-03-16
申请人： NMC, INC. , LOS ALAMOS NATIONAL SECURITY, LLC
发明人： Sangeeta Negi , Richard Thomas Sayre , Shawn Robert Starkenburg
IPC分类号： C12N9/12 , C12N1/12 , C07K14/405
摘要： Phototropin is a blue light receptor, which mediates a variety of blue-light elicited physiological processes in plants and algae. In higher plants these processes include phototropism, chloroplast movement and stomatal opening. In the green alga Chlamydomonas reinhardtii, phototropin plays a vital role in progression of the sexual life cycle and in the control of the eye spot size and light sensitivity Phototropin is also involved in blue-light mediated changes in the synthesis of chlorophylls, carotenoids, chlorophyll binding proteins. We compared the transcriptome of phototropin knock out (PHOT KO) mutant and wild-type parent to analyze differences in gene expression in high light grown cultures (500 μmol photons m−2s−1). Our results indicate the up-regulation of genes involved in photosynthetic electron transport chain, carbon fixation pathway, starch, lipid, and cell cycle control genes. With respect to photosynthetic electron transport genes, genes encoding proteins of the cytochrome b6f and ATP synthase complex were up regulated potentially facilitating proton-coupled electron transfer. In addition genes involved in limiting steps in the Calvin cycle Ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO), Sidoheptulose 1,7 bisphosphatase (SBPase), Glyceraldehyde-3-phosphate dehydrogenase (3PGDH) and that mediate cell-cycle control (CDK) were also up regulated along with starch synthase and fatty acid biosynthesis genes involved in starch and lipid synthesis. In addition, transmission electron micrographs show increased accumulation of starch granules in PHOT mutant compared to wild type, which is consistent with the higher expression of starch synthase genes. Collectively, the altered patterns of gene expression in the PHOT mutants were associated with a two-fold increase in growth and biomass accumulation compared to wild type when grown in environmental photobioreactors (Phenometrics) that simulate a pond environment. In conclusion, our studies suggest that phototropin may be a master gene regulator that suppresses rapid cell growth and promotes gametogenesis and sexual recombination in wild type strains.

10. 发明授权

US10233458B2 Carbon fixation systems in plants and algae 有权
公开(公告)号：US10233458B2
公开(公告)日：2019-03-19
申请号：US15411854
申请日：2017-01-20
申请人： NMC, INC.
发明人： Richard Thomas Sayre , Somya S. Subramanian , Natalia Friedland
IPC分类号： C12N15/82 , C12N1/12 , C07K14/415 , C12P1/00
摘要： Provided are methods for elevating cyclic electron transfer activity, improving carbon concentration, and enhancing carbon fixation in C3 and C4 plants, and algae, and producing biomass or other products from C3 or C4 plants, and algae, selected from among, for example, starches, oils, fatty acids, lipids, cellulose or other carbohydrates, alcohols, sugars, nutraceuticals, pharmaceuticals, fragrance and flavoring compounds, and organic acids, as well as transgenic plants produced thereby. These methods and transgenic plants and algae encompass the expression, or overexpression, of various combinations of genes that improve carbon concentrating systems in plants and algae, such as bicarbonate transport proteins, carbonic anhydrase, light driven proton pump, cyclic electron flow regulators, etc.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式