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1. 发明专利

AU2013323198B2 Dihydro-6-azaphenalene derivatives for the treatment of CNS, oncological diseases and related disorders 未知
公开(公告)号：AU2013323198B2
公开(公告)日：2018-03-29
申请号：AU2013323198
申请日：2013-09-27
申请人： CHERUKU SRINIVASA R , GLADDING JEFFERY A , LEE JOHN W , LOEBELENZ JEAN R , NGUYEN DIEU , NORMAN JAMES J , ROSENFELD CRAIG , THOTA SAMBAIAH , WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC , WARNER JOHN C
发明人： NGUYEN DIEU , GLADDING JEFFERY A , CHERUKU SRINIVASA R , LOEBELENZ JEAN R , NORMAN JAMES J , THOTA SAMBAIAH , LEE JOHN W , ROSENFELD CRAIG , WARNER JOHN C
IPC分类号： C07D471/06 , A61K31/44
摘要： In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.

4. 发明专利

AU2013323198A1 Dihydro-6-azaphenalene derivatives for the treatment of CNS, oncological diseases and related disorders 未知
公开(公告)号：AU2013323198A1
公开(公告)日：2015-04-09
申请号：AU2013323198
申请日：2013-09-27
申请人： WARNER BABCOCK INST FOR GREEN CHEMISTRY LLC , WARNER JOHN , NGUYEN DIEU , GLADDING JEFFERY , CHERUKU SRINIVASA , LOEBELENZ JEAN , NORMAN JAMES , THOTA SAMBAIAH , LEE JOHN , ROSENFELD CRAIG
发明人： WARNER JOHN C , NGUYEN DIEU , GLADDING JEFFERY A , CHERUKU SRINIVASA R , LOEBELENZ JEAN R , NORMAN JAMES J , THOTA SAMBAIAH , LEE JOHN W , ROSENFELD CRAIG
IPC分类号： A61K31/44
摘要： In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.

5. 发明申请

WO2008053029A2 METHOD FOR CONCEALING A PACKET LOSS 审中-公开
标题翻译：防止包装损失的方法
公开(公告)号：WO2008053029A2
公开(公告)日：2008-05-08
申请号：PCT/EP2007/061791
申请日：2007-10-31
申请人： GOTTFRIED WILHELM LEIBNIZ UNIVERSITÄT HANNOVER , NGUYEN, Dieu Thanh , EDLER, Bernd , OSTERMANN, Jörn , STEFANOSKI, Nikolce
发明人： NGUYEN, Dieu Thanh , EDLER, Bernd , OSTERMANN, Jörn , STEFANOSKI, Nikolce
IPC分类号： H04N19/895
CPC分类号： H04N21/2389 , H04N19/102 , H04N19/139 , H04N19/142 , H04N19/177 , H04N19/188 , H04N19/30 , H04N19/34 , H04N19/44 , H04N19/46 , H04N19/61 , H04N19/895 , H04N21/4385
摘要： A method of concealing a packet loss during video decoding is provided. An input stream having a plurality of network abstraction layer units NAL is received. A loss of a network abstraction layer unit in a group of pictures in the input stream is detected. A valid network abstraction layer unit order from the available network abstraction layer units is outputted. The network abstraction layer unit order is received by a video coding layer (VCL) and data is outputted.
摘要翻译：提供了一种在视频解码期间隐藏分组丢失的方法。接收具有多个网络抽象层单元NAL的输入流。检测输入流中的一组图像中的网络抽象层单元的丢失。输出来自可用网络抽象层单元的有效网络抽象层单元顺序。网络抽象层单元顺序由视频编码层（VCL）接收，数据被输出。

6. 发明申请

WO2014052906A1 DIHYDRO-6-AZAPHENALENE DERIVATIVES FOR THE TREATMENT OF CNS, ONCOLOGICAL DISEASES AND RELATED DISORDERS 审中-公开
标题翻译：用于治疗CNS，肿瘤疾病和相关疾病的二氢六嗪类衍生物
公开(公告)号：WO2014052906A1
公开(公告)日：2014-04-03
申请号：PCT/US2013/062429
申请日：2013-09-27
申请人： WARNER BABCOCK INSTITUTE FOR GREEN CHEMISTRY, LLC , WARNER, John, C. , NGUYEN, Dieu , GLADDING, Jeffery, A. , CHERUKU, Srinivasa, R. , LOEBELENZ, Jean, R. , NORMAN, James, J. , THOTA, Sambaiah , LEE, John, W. , ROSENFELD, Craig
发明人： WARNER, John, C. , NGUYEN, Dieu , GLADDING, Jeffery, A. , CHERUKU, Srinivasa, R. , LOEBELENZ, Jean, R. , NORMAN, James, J. , THOTA, Sambaiah , LEE, John, W. , ROSENFELD, Craig
IPC分类号： A61K31/44
CPC分类号： C07D471/06
摘要： In one embodiment, the present application discloses 2-aza-, 2-oxa- and 2-thia-2,3-dihydro-6-azaphenalene compounds and compositions, and methods for treating a neurological disease in a patient in need thereof using the compounds and compositions as disclosed herein.
摘要翻译：在一个实施方案中，本申请公开了2-氮杂 - ，2-氧杂 - 和2-硫杂-2,3-二氢-6-氮杂萘化合物及其组合物，以及在有需要的患者中治疗神经疾病的方法，其使用化合物和组合物。

7. 发明申请

WO2008053029A3 METHOD FOR CONCEALING A PACKET LOSS 审中-公开
标题翻译：用于隐藏分组丢失的方法
公开(公告)号：WO2008053029A3
公开(公告)日：2008-06-26
申请号：PCT/EP2007061791
申请日：2007-10-31
申请人： UNIV HANNOVER , NGUYEN DIEU THANH , EDLER BERND , OSTERMANN JOERN , STEFANOSKI NIKOLCE
发明人： NGUYEN DIEU THANH , EDLER BERND , OSTERMANN JOERN , STEFANOSKI NIKOLCE
IPC分类号： H04N19/895 , H04N7/24 , H04N7/26 , H04N7/36
CPC分类号： H04N21/2389 , H04N19/102 , H04N19/139 , H04N19/142 , H04N19/177 , H04N19/188 , H04N19/30 , H04N19/34 , H04N19/44 , H04N19/46 , H04N19/61 , H04N19/895 , H04N21/4385
摘要： A method of concealing a packet loss during video decoding is provided. An input stream having a plurality of network abstraction layer units NAL is received. A loss of a network abstraction layer unit in a group of pictures in the input stream is detected. A valid network abstraction layer unit order from the available network abstraction layer units is outputted. The network abstraction layer unit order is received by a video coding layer (VCL) and data is outputted.
摘要翻译：提供了在视频解码期间隐藏分组丢失的方法。接收具有多个网络抽象层单元NAL的输入流。检测输入流中一组图像中网络抽象层单元的丢失。输出来自可用网络抽象层单元的有效网络抽象层单元顺序。网络抽象层单元顺序由视频编码层（VCL）接收并输出数据。

8. 发明申请

WO2006108654A3 METHOD AND APPARATUS FOR ENHANCED VIDEO CODING 审中-公开
公开(公告)号：WO2006108654A3
公开(公告)日：2006-10-19
申请号：PCT/EP2006/003410
申请日：2006-04-13
申请人： UNIVERSITÄT HANNOVER , VATIS, Yuri , EDLER, Bernd , WASSERMANN, Ingolf , NGUYEN, Dieu, Thanh , OSTERMANN, Jörn
发明人： VATIS, Yuri , EDLER, Bernd , WASSERMANN, Ingolf , NGUYEN, Dieu, Thanh , OSTERMANN, Jörn
IPC分类号： H04N7/26 , H04N7/34 , H04N7/36 , H04N7/46 , H04N7/50 , G06T5/00 , H03H17/06 , G06T5/20 , H03H17/02
摘要： Standard video compression techniques apply motion-compensated prediction combined with transform coding of the prediction error. In the context of prediction with fractional-pel motion vector resolution it was shown, that aliasing components contained in an image signal are limiting the prediction efficiency obtained by motion compensation. In order to consider aliasing, quantization and motion estimation errors, camera noise, etc., we analytically developed a twodimensional (2D) non-separable interpolation filter, which is independently calculated for each frame by minimizing the prediction error energy. For every fractional-pel position to be interpolated, an individual set of 2D filter coefficients is determined. Since transmitting filter coefficients as side information results in an additional bit rate, which is almost constant for different image resolutions and total bit rates, the loss in coding gain increases when total bit rates sink. Therefore, we developed an algorithm, which regards the non-separable two-dimensional filter as a polyphase filter. For each frame, predicting the interpolation filter impulse response through evaluation of the polyphase filter, we only have to encode the prediction error of the filter coefficients.

9. 发明申请

WO2006108654A2 METHOD AND APPARATUS FOR ENHANCED VIDEO CODING 审中-公开
标题翻译：用于增强视频编码的方法和装置
公开(公告)号：WO2006108654A2
公开(公告)日：2006-10-19
申请号：PCT/EP2006003410
申请日：2006-04-13
申请人： UNIV HANNOVER , VATIS YURI , EDLER BERND , WASSERMANN INGOLF , NGUYEN DIEU THANH , OSTERMANN JOERN
发明人： VATIS YURI , EDLER BERND , WASSERMANN INGOLF , NGUYEN DIEU THANH , OSTERMANN JOERN
IPC分类号： H04N7/26
CPC分类号： H04N19/59 , H04N19/117 , H04N19/136 , H04N19/174 , H04N19/176 , H04N19/182 , H04N19/187 , H04N19/196 , H04N19/31 , H04N19/33 , H04N19/46 , H04N19/463 , H04N19/51 , H04N19/523 , H04N19/593 , H04N19/61
摘要： Standard video compression techniques apply motion-compensated prediction combined with transform coding of the prediction error. In the context of prediction with fractional-pel motion vector resolution it was shown, that aliasing components contained in an image signal are limiting the prediction efficiency obtained by motion compensation. In order to consider aliasing, quantization and motion estimation errors, camera noise, etc., we analytically developed a twodimensional (2D) non-separable interpolation filter, which is independently calculated for each frame by minimizing the prediction error energy. For every fractional-pel position to be interpolated, an individual set of 2D filter coefficients is determined. Since transmitting filter coefficients as side information results in an additional bit rate, which is almost constant for different image resolutions and total bit rates, the loss in coding gain increases when total bit rates sink. Therefore, we developed an algorithm, which regards the non-separable two-dimensional filter as a polyphase filter. For each frame, predicting the interpolation filter impulse response through evaluation of the polyphase filter, we only have to encode the prediction error of the filter coefficients.
摘要翻译：标准视频压缩技术应用运动补偿预测与预测误差的变换编码相结合。在分数像素运动矢量分辨率的预测的上下文中，显示了包含在图像信号中的混叠分量限制了通过运动补偿获得的预测效率。为了考虑混叠，量化和运动估计误差，摄像机噪声等，我们分析开发了一种二维（2D）不可分离内插滤波器，通过最小化预测误差能量对每帧进行独立计算。对于要插值的每个小数像素位置，确定一组二维滤波器系数。由于发送滤波器系数作为侧信息导致附加比特率，其对于不同的图像分辨率和总比特率几乎是恒定的，所以当总比特率下降时，编码增益的损失增加。因此，我们开发了一种将不可分离的二维滤波器作为多相滤波器的算法。对于每个帧，通过评估多相滤波器来预测内插滤波器脉冲响应，我们只需要对滤波器系数的预测误差进行编码。

10. 发明申请

WO1994011382A1 ANTINEOPLASTIC HETERONAPHTHOQUINONES 审中-公开
标题翻译： ANTINEOPLOSTIC HETERONAPHTHOQUINONES
公开(公告)号：WO1994011382A1
公开(公告)日：1994-05-26
申请号：PCT/CA1993000463
申请日：1993-11-05
申请人： BIOCHEM PHARMA INC. , ATTARDO, Giorgio , BREINING, Tibor , COURCHESNE, Marc , KRAUS, Jean-Louis , LAMOTHE, Serge , LAVALLEE, Jean-François , LEBEAU, Elaine , NGUYEN, Dieu , REJ, Rabindra , ST-DENIS, Yves , WANG, Wuyi , XU, Yao-Chang , BARBEAU, France
发明人： BIOCHEM PHARMA INC.
IPC分类号： C07H17/00
CPC分类号： C07H15/252 , C07D311/76 , C07D311/92 , C07D335/08 , C07H17/00 , C07H17/04
摘要： Tricyclic heteronaphthoquinone derivatives, that have antineoplastic activity, are disclosed, together with processes for their synthesis. Some of these anti-neoplastics compounds have a saccharide moiety. Some members of this structurally distinct group exhibit activity against multiple drug resistant cancer cells.
摘要翻译：公开了具有抗肿瘤活性的三环杂萘醌衍生物及其合成方法。这些抗肿瘤化合物中的一些具有糖部分。该结构不同组的一些成员表现出抗多种耐药性癌细胞的活性。

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