专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO2005047714A1 FASTENERS AND OTHER ASSEMBLIES 审中-公开
标题翻译：紧固件和其他装配
公开(公告)号：WO2005047714A1
公开(公告)日：2005-05-26
申请号：PCT/AU2004/001580
申请日：2004-11-17
申请人： TELEZYGOLOGY INC , RUDDUCK, Dickory , GOLDSPINK, Lachlan, Richard , PARK, Joshua, Robert , NG, Nicholas, Anthony , BLATTMANN, Lee, David , KELLIHER, Christopher, Gerarh , FARREN-PRICE, Edward, David, James
发明人： RUDDUCK, Dickory , GOLDSPINK, Lachlan, Richard , PARK, Joshua, Robert , NG, Nicholas, Anthony , BLATTMANN, Lee, David , KELLIHER, Christopher, Gerarh , FARREN-PRICE, Edward, David, James
IPC分类号： F16B19/02
CPC分类号： F16B21/16 , B60K2015/053 , B60K2015/0561 , B62D27/00 , B62D65/02 , B62J1/08 , B62J9/00 , B62J11/00 , B62J17/04 , B62J2099/0033 , E05B47/0009 , E05B47/06 , E05B81/04 , E05B83/34 , E05B2063/0026 , F16B1/0014 , F16B21/06 , F16B21/086 , F16B21/183 , F16B21/186 , Y10T24/45461 , Y10T24/45466 , Y10T24/45471 , Y10T70/7062
摘要： The invention discloses several types of fastener, fastening systems, fastener assmeblies and related areas. In particular, the invention discloses a releasable fastening system (150) which has a pin (152) with a locking cavity (163). The pin is intended for insertion in an aperture (154). A locking means (158, 160) engages the locking cavity (163) of the pin (152) when the pin (152) is received in the aperture (154). The system (150) also includes unlocking means (162) which includes material adapted to contract when activated. When a material contracts, engagement means (158) included in the locking means (158, 160), disengage the locking cavity (154).
摘要翻译：本发明公开了几种类型的紧固件，紧固系统，紧固件构件和相关区域。特别地，本发明公开了一种具有带有锁定腔（163）的销（152）的可释放紧固系统（150）。销用于插入孔（154）中。当销（152）被容纳在孔（154）中时，锁定装置（158,160）接合销（152）的锁定腔（163）。系统（150）还包括解锁装置（162），其包括适于在被激活时收缩的材料。当材料收缩时，包括在锁定装置（158,160）中的接合装置（158）脱离锁定腔（154）。

2. 发明申请

WO2004085860A1 FASTENER FOR AIR BAGS AND OTHER USES 审中-公开
标题翻译：空气袋紧固件和其他用途
公开(公告)号：WO2004085860A1
公开(公告)日：2004-10-07
申请号：PCT/AU2004/000371
申请日：2004-03-24
申请人： TELEZYGOLOGY INC. , RUDDUCK, Dickory , HORT, Michael, John, Laybourne , MCARTHUR, Adam, Russell , NG, Nicholas, Anthony , SIZER, Geoffrey, David
发明人： RUDDUCK, Dickory , HORT, Michael, John, Laybourne , MCARTHUR, Adam, Russell , NG, Nicholas, Anthony , SIZER, Geoffrey, David
IPC分类号： F16B1/00
CPC分类号： F16B5/065 , B60R21/20 , F16B1/0014 , F16B5/0657 , F16B21/16 , Y10T292/20
摘要： The invention provides a fastener (10) for releasably securing a first element, such as an air bag (12) to a second element such as a bracket (14) located in a vehicle. Fastener (10) has a locking pin (16) which is movable between a locked position and a release position. Locking pin (16) has an engageable head (18). Fastener (10) includes means such as clip (22) for engaging head (18). Locking pin (16) is biased to the release position, for example, by spring (26). Fastener (10) includes an actuator such as spring (32), comprising or including shape memory alloy and adapted to elongate upon application of appropriate energy. When spring (32) is elongated, it causes locking pin (16) to move to the release position. The invention also provides a fastener assembly (130) including at least one post (122) having a groove (124). Fastener assembly (130) includes a bar or latch, for example, in the form of wire (126) adapted to engage the groove (124). Attached to bar (126) is connecting means, such as shape memory spring (128). Upon application of suitable energy, spring (128) is adapted to change shape and draw bar (126) out of engagement with groove (124).
摘要翻译：本发明提供了一种紧固件（10），用于将诸如气囊（12）的第一元件可释放地固定到诸如位于车辆中的支架（14）的第二元件。紧固件（10）具有可在锁定位置和释放位置之间移动的锁定销（16）。锁定销（16）具有可接合头部（18）。紧固件（10）包括用于接合头部（18）的诸如夹子（22）的装置。锁定销（16）例如通过弹簧（26）偏压到释放位置。紧固件（10）包括诸如弹簧（32）的致动器，包括或包括形状记忆合金，并适于在施加适当能量时伸长。当弹簧（32）伸长时，使锁定销（16）移动到释放位置。本发明还提供一种紧固件组件（130），其包括具有凹槽（124）的至少一个柱（122）。紧固件组件130包括例如以适于接合凹槽（124）的线（126）形式的杆或闩锁。连接到杆（126）的是诸如形状记忆弹簧（128）的连接装置。在施加合适的能量时，弹簧（128）适于改变形状并将拉杆（126）脱离与凹槽（124）的接合。

3. 发明申请

WO2014141038A3 MARKERS ASSOCIATED WITH WNT INHIBITORS 审中-公开
标题翻译：与WNT抑制剂相关的标记
公开(公告)号：WO2014141038A3
公开(公告)日：2014-11-27
申请号：PCT/IB2014059585
申请日：2014-03-10
申请人： IRM LLC , CHE JIANWEI , HARRIS JENNIFER , HSIN-I HSIEH MINDY , LI JIE , LIU JUN , NG NICHOLAS
发明人： CHE JIANWEI , HARRIS JENNIFER , HSIN-I HSIEH MINDY , LI JIE , LIU JUN , NG NICHOLAS
IPC分类号： G01N33/574 , A61P35/00
CPC分类号： C12Q1/6886 , A61K31/444 , A61K31/497 , A61K31/501 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N33/57407 , G01N33/57484 , G01N2800/52
摘要： The invention provides methods of monitoring differential gene expression of biomarkers to determine patient sensitivity to Wnt inhibitor, methods of determining the sensitivity of a cell to an Wnt inhibitor by measuring biomarkers, methods of screening for candidate Wnt inhibitor, Wnt inhibitor for use in head and neck squamous cell carcinoma.
摘要翻译：本发明提供监测生物标志物的差异基因表达以确定患者对Wnt抑制剂的敏感性的方法，通过测量生物标志物来测定细胞对Wnt抑制剂的敏感性的方法，筛选候选Wnt抑制剂的方法，用于头部的Wnt抑制剂和颈鳞状细胞癌。

4. 发明申请

WO2014141038A2 MARKERS ASSOCIATED WITH WNT INHIBITORS 审中-公开
标题翻译：与WNT抑制剂相关的标记
公开(公告)号：WO2014141038A2
公开(公告)日：2014-09-18
申请号：PCT/IB2014/059585
申请日：2014-03-10
申请人： IRM LLC , CHE, Jianwei , HARRIS, Jennifer , HSIN-I HSIEH, Mindy , LI, Jie , LIU, Jun , NG, Nicholas
发明人： CHE, Jianwei , HARRIS, Jennifer , HSIN-I HSIEH, Mindy , LI, Jie , LIU, Jun , NG, Nicholas
IPC分类号： G01N33/574
CPC分类号： C12Q1/6886 , A61K31/444 , A61K31/497 , A61K31/501 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N33/57407 , G01N33/57484 , G01N2800/52
摘要： The invention provides methods of monitoring differential gene expression of biomarkers to determine patient sensitivity to Wnt inhibitor, methods of determining the sensitivity of a cell to an Wnt inhibitor by measuring biomarkers, methods of screening for candidate Wnt inhibitor, Wnt inhibitor for use in head and neck squamous cell carcinoma.
摘要翻译：本发明提供监测生物标志物的差异基因表达以确定患者对Wnt抑制剂的敏感性的方法，通过测量生物标志物确定细胞对Wnt抑制剂的敏感性的方法，筛选候选Wnt抑制剂的方法，用于头颈部鳞状细胞癌的Wnt抑制剂。

5. 发明申请

WO2013130364A1 CANCER PATIENT SELECTION FOR ADMINISTRATION OF WNT SIGNALING INHIBITORS USING RNF43 MUTATION STATUS 审中-公开
标题翻译：使用RNF43突变状态的WNT信号抑制剂治疗癌症患者选择
公开(公告)号：WO2013130364A1
公开(公告)日：2013-09-06
申请号：PCT/US2013/027441
申请日：2013-02-22
申请人： NOVARTIS AG , CONG, Feng , HAO, Huaixiang , HSIEH, Hsin-i , JIANG, Xiaomo , LIU, Jun , NG, Nicholas
发明人： CONG, Feng , HAO, Huaixiang , HSIEH, Hsin-i , JIANG, Xiaomo , LIU, Jun , NG, Nicholas
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6886 , A61K31/497 , C12Q2600/106 , C12Q2600/156 , C12Q2600/158 , G01N33/57438 , G01N33/57492 , G01N2800/52
摘要： Disclosed are biomarkers, methods and assay for the identification of cancer patients who are predicted to benefit from the therapeutic administration of Wnt antagonist. The biomarkers include detection of RNF43 and ZNRF3 gene deletion, reduced RNF43 and ZNRF3 mRNA expression, reduced RNF43 and ZNRF3 protein expression, RNF43 and ZNRF3 inactivation mutation, phosphorylated LRP6, phophorylated Dishevelleds, and the expression of Frizzleds. These biomarkers can be associated with the better outcome for cancer patients treated with Wnt pathway inhibitors.
摘要翻译：公开了预测从Wnt拮抗剂的治疗施用中受益的癌症患者的鉴定的生物标志物，方法和测定。生物标志物包括RNF43和ZNRF3基因缺失的检测，RNF43和ZNRF3 mRNA表达的降低，RNF43和ZNRF3蛋白表达的降低，RNF43和ZNRF3失活突变，磷酸化的LRP6，磷酸化的Dishevelleds和Frizzleds的表达。这些生物标志物可以与用Wnt途径抑制剂治疗的癌症患者的更好的结果相关联。

6. 发明申请

WO2004046568A1 BOLT ASSEMBLY, METHOD AND DEVICE FOR RELEASE, AND COMPUTER SYSTEM 审中-公开
标题翻译：螺栓组件，用于释放的方法和装置以及计算机系统
公开(公告)号：WO2004046568A1
公开(公告)日：2004-06-03
申请号：PCT/AU2003/001539
申请日：2003-11-19
申请人： TELEZYGOLOGY INC , RUDDUCK, Dickory , HORT, Michael, John, Laybourne , NG, Nicholas, Anthony , SIZER, Geoffrey, David
发明人： RUDDUCK, Dickory , HORT, Michael, John, Laybourne , NG, Nicholas, Anthony , SIZER, Geoffrey, David
IPC分类号： F16B37/08
CPC分类号： H05K3/301 , F16B1/0014 , F16B33/02 , F16B35/04 , F16B37/08 , F16B2001/0035 , H05K2201/0308 , H05K2201/10598
摘要： Quick release bolt assembly (10) included shank (12) and head (14) of larger cross-section than that of shank (12). The screw thread of shank (12) is adapted to rotatably engage with a complementary screw thread in a nut. Disengagement means are adapted in use to disengage the head (14) or the nut without rotation of the nut or shank (12). The disengagement means includes a material (18) such as shape memory alloy or epoxy resin, adapted to change form to facilitate engagement when activated. Activation may take place by a direct power supply or remotely by a radio frequency, magnetic, ultrasonic or infra red signal. Bolt (10) can be used for anchoring seat belts. Computer systems and methods for the identification of a target, including enquiring as to the status of the target and having means to command the target to change the status are also disclosed and claimed.
摘要翻译：快速释放螺栓组件（10）包括柄部（12）和头部（14），其横截面大于柄部（12）的横截面。柄（12）的螺纹适于与螺母中的互补螺纹旋转地接合。拆卸装置适用于在螺母或柄（12）旋转的情况下使头部（14）或螺母脱开。分离装置包括诸如形状记忆合金或环氧树脂的材料（18），其适于改变形式以便当被激活时便于接合。激活可以通过直接电源或远程通过射频，磁，超声波或红外线信号进行。螺栓（10）可用于固定安全带。还公开并声明了用于识别目标的计算机系统和方法，包括询问目标的状态并具有指示目标改变状态的方法。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式