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1. 发明申请

WO2005046735A1 A REAGENT SYSTEM AND METHOD FOR MODIFYING THE LUMINESCENCE OF LANTHANIDE(III) MACROCYCLIC COMPLEXES 审中-公开
标题翻译：一种用于改性兰（III）大环化合物的发光体系和方法
公开(公告)号：WO2005046735A1
公开(公告)日：2005-05-26
申请号：PCT/US2004/037314
申请日：2004-11-08
申请人： NEWPORT INSTRUMENTS , LEIF, Robert, C. , YANG, Sean , VALLARINO, Lidia
发明人： LEIF, Robert, C. , YANG, Sean , VALLARINO, Lidia
IPC分类号： A61K49/00
CPC分类号： G01N33/533 , G01N21/6428 , G01N2021/6441
摘要： Disclosed is a spectrofluorimetrically detectable luminescent composition consisting essentially of at least one energy transfer acceptor lanthanide(III) complex having an emission spectrum maximum in the range from 300 to 2000 nanometers and a luminescence-enhancing amount of at least one energy transfer donor selected from the group consisting of a fluorophore, a lumiphore, an organic compound, a salt of an organic ion, a metal ion, a metal ion complex, or a combination thereof. Such energy transfer donor enhances the luminescence of at least one energy transfer acceptor lanthanide(III) complex, with the conditions that the emission spectrum of any energy transfer donor differs from that of its energy transfer acceptor lanthanide(III) complex; and such energy transfer donor can be dissolved to form a unitary solution in a solvent having an evaporation rate at least as great as that of water.
摘要翻译：公开了一种分光荧光测定的发光组合物，其基本上由至少一种发射光谱最大值在300至2000纳米的能量转移受体镧系元素（III）络合物组成，以及至少一种能量转移供体的发光增强量，其选自由荧光团，荧光体，有机化合物，有机离子的盐，金属离子，金属离子络合物或其组合组成的组。这种能量转移供体增强至少一种能量转移受体镧系元素（III）络合物的发光，条件是任何能量转移供体的发射光谱与其能量转移受体镧系元素（III）络合物的发射光谱不同; 并且这样的能量转移供体可以溶解在具有与水的蒸发速率至少一样大的溶剂中的单一溶液。

2. 发明申请

WO2003104801A1 CENTRIFUGAL CYTOLOGY SYSTEM, CHAMBER BLOCK AND METHOD FOR THE PREPARATION OF TREATED MONOLAYERS OF SAMPLE MATERIAL 审中-公开
标题翻译：离心细胞系统，腔体和制备样品处理单层的方法
公开(公告)号：WO2003104801A1
公开(公告)日：2003-12-18
申请号：PCT/US2003/011394
申请日：2003-04-14
申请人： NEWPORT INSTRUMENTS , LEIF, Robert, Cary
发明人： LEIF, Robert, Cary
IPC分类号： G01N33/48
CPC分类号： B01L3/5025 , B01L2300/0803 , B01L2400/0409 , B01L2400/0633 , G01N1/2813 , G01N1/312 , G01N35/025 , G01N2035/00504 , G01N2035/0449 , Y10T436/25375
摘要： An apparatus and method for the automated preparation of treated monolayers of sample material, comprising: a centrifuge having a rotor (12) carrying removable chamber blocks (14); sample and reagent dispensers (26) and control systems (20). First, centrifugal force sediments sample material discretely to form a monolayer onto a receiving surface member (32) on one of the chamber blocks (14), while the same centrifugal force opens a valve (48) in the chamber block (14) to drain sample material. Then, centrifugal force delivers sequentially into discrete chamber blocks (14) discrete treating agents, during which time the sampler material monolayer is held in place on the receiving surface member (32) by centrifugal force. Then, each chamber block (14) is drained centrifugally through its already opened valve (48). Each treated sampler material is confined to an individual chamber block (14). Batch and random access delivery of treating agents can be employed. Each chamber block (14) includes separate inlets for the sample and treating agents.
摘要翻译：一种用于自动制备样品材料的经处理的单层的装置和方法，包括：离心机，其具有承载可移除的腔室块（14）的转子（12）; 样品和试剂分配器（26）和控制系统（20）。首先，离心力离散地沉淀样品材料以在其中一个室块（14）上的接收表面构件（32）上形成单层，同时离心力打开腔室块（14）中的阀（48）以排出样品材料。然后，离心力顺序地输送到离散的处理剂块（14）中，在此期间采样器材料单层通过离心力保持在接收表面构件（32）上的适当位置。然后，每个室块（14）通过其已经打开的阀（48）离心排出。每个经处理的采样器材料被限制在单独的室块（14）中。可以采用处理剂的批次和随机存取递送。每个室块（14）包括用于样品和处理剂的单独入口。

3. 发明专利

DE1598849C3 未知
公开(公告)号：DE1598849C3
公开(公告)日：1974-10-10
申请号：DE1598849
申请日：1965-09-06
申请人： NEWPORT INSTRUMENTS LTD., NEWPORT PAGNELL, BUCKINGHAMSHIRE (GROSSBRITANNIEN)
发明人： WATSON, EDWARD, HAMPTON, MIDDLESEX (GROSSBRITANNIEN)
IPC分类号： G01R33/46 , G01N27/78
摘要： 1,125,481. Electro-physical measurement. NEWPORT INSTRUMENTS Ltd. Sept. 3, 1965 [Sept. 7, 1964], No, 36550/64. Heading G1N. In apparatus utilizing nuclear magnetic resonance to measure the moisture content of e.g. tobacco, a known reference sample and a test sample are tested sequentially and the response due to the known sample is used as a reference to calibrate the apparatus. The two samples A and B, are subjected simultaneously to a high frequency field derived from oscillator and resonance detector 26, and a varying unidirectional field consisting of a standing bias from battery 18 and a triangular sweep current from sweep generator 23. The standing bias on the reference sample is adjusted to a different level from that on the test sample so that nuclear resonance occurs at a different point in the sweep cycle. Both sets of resonance response pulses from the detector 26 are passed through a common high gain amplifier 28 and meter amplifier 30, the overall gain being adjustable by a potential divider 29. The two sets of amplified pulses are passed to separate meters 35, 39 by gating relays 36, 40 energized by the sweep generator 23 through adjustable time-delay circuits 41. The gain of the amplifier is thenadjusted manually or automatically, Fig. 9 (not shown), to bring the reading on meter 35 due to the moisture content of the reference sample to a given datum value, the value of the test sample can then be read directly off meter 39 which is suitably scaled. In a modification, Fig. 10 (not shown), both samples lie within a common magnet system and an auxiliary D.C. bias winding is placed adjacent the reference sample.

4. 发明专利

DE1598849B2 未知
公开(公告)号：DE1598849B2
公开(公告)日：1974-03-07
申请号：DE1598849
申请日：1965-09-06
申请人： NEWPORT INSTRUMENTS LTD., NEWPORT PAGNELL, BUCKINGHAMSHIRE (GROSSBRITANNIEN)
发明人： WATSON, EDWARD, HAMPTON, MIDDLESEX (GROSSBRITANNIEN)
IPC分类号： G01R33/46 , G01N27/78
摘要： 1,125,481. Electro-physical measurement. NEWPORT INSTRUMENTS Ltd. Sept. 3, 1965 [Sept. 7, 1964], No, 36550/64. Heading G1N. In apparatus utilizing nuclear magnetic resonance to measure the moisture content of e.g. tobacco, a known reference sample and a test sample are tested sequentially and the response due to the known sample is used as a reference to calibrate the apparatus. The two samples A and B, are subjected simultaneously to a high frequency field derived from oscillator and resonance detector 26, and a varying unidirectional field consisting of a standing bias from battery 18 and a triangular sweep current from sweep generator 23. The standing bias on the reference sample is adjusted to a different level from that on the test sample so that nuclear resonance occurs at a different point in the sweep cycle. Both sets of resonance response pulses from the detector 26 are passed through a common high gain amplifier 28 and meter amplifier 30, the overall gain being adjustable by a potential divider 29. The two sets of amplified pulses are passed to separate meters 35, 39 by gating relays 36, 40 energized by the sweep generator 23 through adjustable time-delay circuits 41. The gain of the amplifier is thenadjusted manually or automatically, Fig. 9 (not shown), to bring the reading on meter 35 due to the moisture content of the reference sample to a given datum value, the value of the test sample can then be read directly off meter 39 which is suitably scaled. In a modification, Fig. 10 (not shown), both samples lie within a common magnet system and an auxiliary D.C. bias winding is placed adjacent the reference sample.

5. 发明授权

EP1684808B1 A REAGENT SYSTEM AND METHOD FOR MODIFYING THE LUMINESCENCE OF LANTHANIDE(III) MACROCYCLIC COMPLEXES 有权
标题翻译：试剂的系统和方法进行修改，发光的镧系元素（III）的大环络合物
公开(公告)号：EP1684808B1
公开(公告)日：2013-01-09
申请号：EP04818664.7
申请日：2004-11-08
申请人： Newport Instruments
发明人： LEIF, Robert, C. , YANG, Sean , VALLARINO, Lidia, Department of Chemistry
IPC分类号： A61K49/00 , C12Q1/00 , G01N21/76 , G01N33/533
CPC分类号： G01N33/533 , G01N21/6428 , G01N2021/6441

6. 发明公开

EP1684808A1 A REAGENT SYSTEM AND METHOD FOR MODIFYING THE LUMINESCENCE OF LANTHANIDE(III) MACROCYCLIC COMPLEXES 有权
标题翻译：试剂的系统和方法进行修改，发光的镧系元素（III）的大环络合物
公开(公告)号：EP1684808A1
公开(公告)日：2006-08-02
申请号：EP04818664.7
申请日：2004-11-08
申请人： Newport Instruments
发明人： LEIF, Robert, C. , YANG, Sean , VALLARINO, Lidia, Department of Chemistry
IPC分类号： A61K49/00 , C12Q1/00 , G01N21/76
CPC分类号： G01N33/533 , G01N21/6428 , G01N2021/6441
摘要： Disclosed is a spectrofluorimetrically detectable luminescent composition consisting essentially of at least one energy transfer acceptor lanthanide(III) complex having an emission spectrum maximum in the range from 300 to 2000 nanometers and a luminescence-enhancing amount of at least one energy transfer donor selected from the group consisting of a fluorophore, a lumiphore, an organic compound, a salt of an organic ion, a metal ion, a metal ion complex, or a combination thereof. Such energy transfer donor enhances the luminescence of at least one energy transfer acceptor lanthanide(III) complex, with the conditions that the emission spectrum of any energy transfer donor differs from that of its energy transfer acceptor lanthanide(III) complex; and such energy transfer donor can be dissolved to form a unitary solution in a solvent having an evaporation rate at least as great as that of water.

7. 发明公开

EP1504260A1 CENTRIFUGAL CYTOLOGY SYSTEM, CHAMBER BLOCK AND METHOD FOR THE PREPARATION OF TREATED MONOLAYERS OF SAMPLE MATERIAL 审中-公开
标题翻译：离心CYTOLOGIESYSTEM，室LOCKING及其制造方法样品材料处理MONO LAYERS
公开(公告)号：EP1504260A1
公开(公告)日：2005-02-09
申请号：EP03728386.8
申请日：2003-04-14
申请人： Newport Instruments
发明人： LEIF, Robert, Cary
IPC分类号： G01N33/48 , G01N1/18
CPC分类号： B01L3/5025 , B01L2300/0803 , B01L2400/0409 , B01L2400/0633 , G01N1/2813 , G01N1/312 , G01N35/025 , G01N2035/00504 , G01N2035/0449 , Y10T436/25375
摘要： An apparatus and method for the automated preparation of treated monolayers of sample material, comprising: a centrifuge having a rotor (12) carrying removable chamber blocks (14); sample and reagent dispensers (26) and control systems (20). First, centrifugal force sediments sample material discretely to form a monolayer onto a receiving surface member (32) on one of the chamber blocks (14), while the same centrifugal force opens a valve (48) in the chamber block (14) to drain sample material. Then, centrifugal force delivers sequentially into discrete chamber blocks (14) discrete treating agents, during which time the sampler material monolayer is held in place on the receiving surface member (32) by centrifugal force. Then, each chamber block (14) is drained centrifugally through its already opened valve (48). Each treated sampler material is confined to an individual chamber block (14). Batch and random access delivery of treating agents can be employed. Each chamber block (14) includes separate inlets for the sample and treating agents.

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