专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明专利

JP2013020644A Hybrid control device 审中-公开
标题翻译：混合控制装置
公开(公告)号：JP2013020644A
公开(公告)日：2013-01-31
申请号：JP2012222508
申请日：2012-10-04
申请人： Neurosciences Research Foundation Inc , ニューロサイエンシーズリサーチファンデーションインコーポレイテッド
发明人： FLEISCHER JASON G , BOTOND SZATMARY , HATSON DONALD B , MOORE DOUGLAS A , JAMES A SNOOK , GERALD M EDELMAN , JEFFREY KRICHMAR
IPC分类号： G05B13/02 , B25J5/00 , B25J13/08
CPC分类号： G06N3/0427 , G05B13/027 , G05B15/02 , G05B2219/39292 , G05B2219/39385 , G06K9/00664 , G06N3/02
摘要： PROBLEM TO BE SOLVED: To provide robots, especially the robots adapted to learn about their environment.SOLUTION: A hybrid control system for a robot can include a neuronal control portion and a non-neuronal control portion.
摘要翻译：要解决的问题：提供机器人，特别是适合了解其环境的机器人。解决方案：用于机器人的混合控制系统可以包括神经元控制部分和非神经元控制部分。版权所有（C）2013，JPO＆INPIT

2. 发明申请

US20130304447A1 Spike-timing computer modeling of working memory 审中-公开
标题翻译：工作记忆的尖峰计时建模
公开(公告)号：US20130304447A1
公开(公告)日：2013-11-14
申请号：US13987173
申请日：2013-07-08
申请人： NEUROSCIENCES RESEARCH FOUNDATION, INC.
发明人： Botond Szatmáry , Eugene Izhikevich
IPC分类号： G06F19/12
CPC分类号： G16B5/00 , G06N3/10
摘要： Working memory (WM) is part of the brain's memory system that provides temporary storage and manipulation of information necessary for cognition. Although WM has limited capacity at any given time, it has vast memory content in the sense that it acts on the brain's nearly infinite repertoire of lifetime memories. As described, large memory content and WM functionality emerge spontaneously if the spike-timing nature of neuronal processing is taken into account. The memories are represented by extensively overlapping groups of neurons that exhibit stereotypical time-locked spatiotemporal spike-timing patterns, called polychronous patterns. Using computer-implemented simulations, associative synaptic plasticity in the form of short-term STDP selects such polychronous neuronal groups (PNGs) into WM by temporarily strengthening the synapses of the selected PNGs. This strengthening increases the spontaneous reactivation frequency of the selected PNGs, resulting in irregular, yet systematically changing elevated firing activity patterns consistent with those recorded in vivo during WM tasks. The computer-implemented model implements the relationship between such slowly changing firing rates and precisely timed spikes, and also reveals a novel relationship between WM and the perception of time on the order of seconds.
摘要翻译：工作记忆（WM）是大脑记忆系统的一部分，为认知所需的信息提供临时存储和操纵。虽然WM在任何给定时间的容量有限，但它具有广泛的记忆内容，因为它对大脑几乎无限的生活记忆曲目起作用。如上所述，如果考虑神经元处理的尖峰定时特性，则大的存储器内容和WM功能自发地出现。这些记忆由广泛重叠的神经元组表示，这些神经元表现出刻板的时间锁定时空尖峰定时模式，称为多同步模式。使用计算机实现的模拟，短期STDP形式的关联突触可塑性通过临时加强所选择的PNG的突触，将这样的多进程神经元组（PNG）选择成WM。这种加强增加了所选PNG的自发再激活频率，导致与WM任务期间体内记录的激活活动模式不一致但系统地改变。计算机实现的模型实现了这种缓慢变化的发射速率和精确定时的峰值之间的关系，并且还揭示了WM与几秒钟的时间感知之间的新颖关系。

3. 发明申请

US20030087807A1 Methods for identifying compounds for motion sickness, vertigo and other disorders related to balance and the perception of gravity 失效
标题翻译：用于识别晕车，眩晕和与平衡相关的其他障碍以及重力感知的化合物的方法
公开(公告)号：US20030087807A1
公开(公告)日：2003-05-08
申请号：US10255536
申请日：2002-09-25
申请人： Neurosciences Research Foundation, Inc.
发明人： Ralph J. Greenspan
IPC分类号： A61K038/00 , A61K049/00
CPC分类号： C12Q1/6883 , C12Q2600/158
摘要： The present invention provides a method of identifying a compound that modulates a mammalian vestibular system. The method consists of administering a test compound to an invertebrate, and measuring a geotactic behavior of the invertebrate, where a compound that modulates the geotactic behavior of said invertebrate is characterized as a compound that modulates a mammalian vestibular system. The invention also provides a method of identifying a gene that modulates a mammalian vestibular system consisting of obtaining a first and a second strain of an invertebrate; subjecting the first and second invertebrate strains to conditions in which the first strain exhibits a geotactic behavior different than a geotactic behavior exhibited by the second strain; measuring gene expression levels in the first and second strains, and identifying one or more genes that are differentially expressed in the first strain relative to the second strain, whereby a mammalian gene having substantially the same nucleic acid sequence as the one or more differentially expressed genes modulates the mammalian vestibular system.
摘要翻译：本发明提供了鉴定调节哺乳动物前庭系统的化合物的方法。该方法包括向无脊椎动物施用测试化合物，并测量无脊椎动物的地理行为，其中调节所述无脊椎动物的地理行为的化合物被表征为调节哺乳动物前庭系统的化合物。本发明还提供了鉴定调节哺乳动物前庭系统的基因的方法，所述哺乳动物前庭系统由获得无脊椎动物的第一和第二菌株组成; 使第一和第二无脊椎动物菌株经受第一菌株表现出与第二菌株表现出的地理行为不同的地理行为的条件; 测量第一和第二菌株中的基因表达水平，以及鉴定相对于第二菌株在第一菌株中差异表达的一个或多个基因，由此具有与一个或多个差异表达基因基本上相同的核酸序列的哺乳动物基因调节哺乳动物前庭系统。

4. 发明申请

US20130274919A1 MOBILE BRAIN-BASED DEVICE FOR USE IN A REAL WORLD ENVIRONMENT 审中-公开
标题翻译：用于实际世界环境的基于移动电脑的设备
公开(公告)号：US20130274919A1
公开(公告)日：2013-10-17
申请号：US13915565
申请日：2013-06-11
申请人： Neurosciences Research Foundation, Inc.
发明人： Anil K. Seth , Jeffrey L. McKinstry , Gerald M. Edelman , Jeffrey L. Krichmar
IPC分类号： G06F15/18
CPC分类号： G06N20/00 , G06F3/015 , G06K9/629 , G06N3/004 , G06N3/049 , G16H50/50
摘要： A mobile brain-based device BBD includes a mobile base equipped with sensors and effectors (Neurally Organized Mobile Adaptive Device or NOMAD), which is guided by a simulated nervous system that is an analogue of cortical and sub-cortical areas of the brain required for visual processing, decision-making, reward, and motor responses. The brain-based device BBD learns to discriminate among multiple objects with shared visual features, and associated “target” objects with innately preferred auditory cues. The brain-based device BBD is moveable, in a rich real-world environment involving continual changes in the size and location of visual stimuli due to self-generated or autonomous, movement, and shows that reentrant connectivity and dynamic synchronization provide an effective mechanism for binding the features of visual objects so as to reorganize object features such as color, shape and motion while distinguishing distinct objects in the environment.
摘要翻译：基于移动脑的设备BBD包括配备有传感器和效应器（神经有机移动自适应装置或NOMAD）的移动基座，其由模拟神经系统引导，该模拟神经系统是脑的皮质和皮质下皮区域的类似物，视觉处理，决策，奖励和运动反应。基于脑的设备BBD学习使用共享的视觉特征和相关联的“目标”对象与具有本来优选的听觉线索的多个对象之间进行区分。基于大脑的设备BBD可以在丰富的现实环境中移动，包括由于自我生成或自主运动引起的视觉刺激的大小和位置的持续变化，并且表明可重入连接性和动态同步为绑定视觉对象的特征，以便重新组织对象特征，如颜色，形状和运动，同时区分环境中的不同对象。

5. 发明申请

WO2007033101A3 HYBRID CONTROL DEVICE 审中-公开
公开(公告)号：WO2007033101A3
公开(公告)日：2007-03-22
申请号：PCT/US2006/035357
申请日：2006-09-13
申请人： NEUROSCIENCES RESEARCH FOUNDATION, INC. , FLEISCHER, Jason, G. , SZATMARY, Botond , HUTSON, Donald, B. , MOORE, Douglas, A. , SNOOK, James, A. , EDELMAN, Gerald, M. , KRICHMAR, Jeffrey
发明人： FLEISCHER, Jason, G. , SZATMARY, Botond , HUTSON, Donald, B. , MOORE, Douglas, A. , SNOOK, James, A. , EDELMAN, Gerald, M. , KRICHMAR, Jeffrey
IPC分类号： G06N3/00
摘要： A hybrid control system for a robot can include a neuronal control portion and a non-neuronal control portion.

6. 发明申请

WO2007002731A2 ADDRESSING SCHEME FOR NEURAL MODELING AND BRAIN-BASED DEVICES USING SPECIAL PURPOSE PROCESSOR 审中-公开
标题翻译：使用特殊用途处理器进行神经建模和基于脑的设备的寻址方案
公开(公告)号：WO2007002731A2
公开(公告)日：2007-01-04
申请号：PCT/US2006/025107
申请日：2006-06-28
申请人： NEUROSCIENCES RESEARCH FOUNDATION, INC. , SNOOK, James, A. , SCHERMERHORN, Richard, W.
发明人： SNOOK, James, A. , SCHERMERHORN, Richard, W.
IPC分类号： G06F15/18
CPC分类号： G06F15/7867 , G06N3/063 , G06N3/10
摘要： A special purpose processor (SPP) can use a Field Programmable Gate Array (FPGA) to model a large number of neural elements. The FPGAs or similar programmable device can have multiple cores doing presynaptic, postsynaptic, and plasticity calculations in parallel. Each core can implement multiple neural elements of the neural model.
摘要翻译：专用处理器（SPP）可以使用现场可编程门阵列（FPGA）对大量神经元进行建模。 FPGA或类似的可编程器件可以具有并行执行突触前，突触后和可塑性计算的多个核心。每个核心可以实现神经模型的多个神经元素。

7. 发明申请

WO2014062275A3 VEHICLE CAPABLE OF IN-AIR AND ON-GROUND MOBILITY 审中-公开
公开(公告)号：WO2014062275A3
公开(公告)日：2014-04-24
申请号：PCT/US2013/052999
申请日：2013-07-31
申请人： NEUROSCIENCES RESEARCH FOUNDATION, INC.
发明人： HUTSON, Donald, B.
IPC分类号： B64C25/36
摘要： In specific embodiments, a vehicle propellable through fluids or along surfaces, comprises a main work section and a plurality of propulsion units for propelling the main work section. The main work section supports one or more payloads. The propulsion units each include a rotor system and a ring-shaped wheel at least partially arranged about the rotor system and rotatable about the rotor system. The ring-shaped wheel is arranged at a banked angle relative to the rotor system.

8. 发明申请

WO1998024396A2 METHODS OF TREATING MENTAL DISEASES, INFLAMMATION AND PAIN 审中-公开
标题翻译：治疗精神疾病，炎症和疼痛的方法
公开(公告)号：WO1998024396A2
公开(公告)日：1998-06-11
申请号：PCT/US1997022063
申请日：1997-11-25
申请人： NEUROSCIENCES RESEARCH FOUNDATION, INC.
发明人： NEUROSCIENCES RESEARCH FOUNDATION, INC. , PIOMELLI, Daniele , BELTRAMO, Massimiliano
IPC分类号： A61K00/00
CPC分类号： A61K31/366
摘要： Methods are disclosed for treating or preventing disorders such as mental diseases, inflammation and pain by inhibiting the enzyme anandamide amidohydrolase. A therapeutically effective level of an anandamide amidohydrolase inhibitor is administered such as a therapeutically effective level of a haloenol lactone. Preferably, the haloenol lactone is of formula (I) wherein R is hydrogen, R1 is a halogen, and R2 is selected from the group consisting of aryl, aryloxy, and heteroaryl radicals, derivatives of said haloenol lactones, and mixtures thereof. The haloenol lactone, E-6-(bromomethylene)tetrahydro-3-(1-naphthalenyl)-2H-pyrane-2-one, is most preferred.
摘要翻译：公开了通过抑制酶和酰胺酰胺水解酶来治疗或预防诸如精神疾病，炎症和疼痛的疾病的方法。施用治疗有效量的安南胺酰氨基水解酶抑制剂，例如治疗有效量的卤烯醇内酯。优选地，卤代烯醇内酯具有式（I），其中R是氢，R 1是卤素，R 2选自芳基，芳氧基和杂芳基，所述卤代烯内酯的衍生物及其混合物。卤代烯醇内酯，E-6-（溴亚甲基）四氢-3-（1-萘基）-2H-吡喃-2-酮是最优选的。

9. 发明申请

WO2006019791A2 MOBILE BRAIN-BASED DEVICE HAVING A SIMULATED NERVOUS SYSTEM BASED ON THE HIPPOCAMPUS 审中-公开
标题翻译：具有基于海马的模拟神经系统的基于移动通信的设备
公开(公告)号：WO2006019791A2
公开(公告)日：2006-02-23
申请号：PCT/US2005/024814
申请日：2005-07-13
申请人： NEUROSCIENCES RESEARCH FOUNDATION, INC. , EDELMAN, Gerald, M. , KRICHMAR, Jeffrey, L. , NITZ, Douglas, A.
发明人： EDELMAN, Gerald, M. , KRICHMAR, Jeffrey, L. , NITZ, Douglas, A.
IPC分类号： G06F17/50
CPC分类号： G06N3/08 , G05D1/0088 , G05D1/0242 , G05D1/0246 , G05D1/0272 , G06N3/004 , Y02T10/82
摘要： A brain-based device (BBD) having a physical mobile device NOMAD controlling and under control by a simulated nervous system. The simulated nervous system is based on an intricate anatomy and physiology of the hippocampus and its surrounding neuronal regions including the cortex. The BBD integrates spatial signals from numerous objects in time and provides flexible navigation solutions to aid in the exploration of unknown environments. As NOMAD navigates in its real world environment, the hippocampus of the simulated nervous system organizes multi-modal input information received from sensors on NOMAD over timescales and uses this organization for the development of spatial and episodic memories necessary for navigation.
摘要翻译：具有物理移动设备NOMAD控制并由模拟神经系统控制的基于脑的设备（BBD）。模拟神经系统基于海马及其周围神经元区域（包括皮质）的复杂解剖学和生理学。 BBD可以及时集成来自众多对象的空间信号，并提供灵活的导航解决方案，以帮助探索未知环境。随着NOMAD在现实环境中的导航，模拟神经系统的海马组织了通过时间尺度从NOMAD传感器接收到的多模态输入信息，并利用该组织来开发导航所需的空间和情景记忆。

10. 发明申请

WO1992012500A1 APPARATUS CAPABLE OF FIGURE-GROUND SEGREGATION 审中-公开
标题翻译：装置可以进行图形分割
公开(公告)号：WO1992012500A1
公开(公告)日：1992-07-23
申请号：PCT/US1991009778
申请日：1991-12-30
申请人： NEUROSCIENCES RESEARCH FOUNDATION, INC.
发明人： NEUROSCIENCES RESEARCH FOUNDATION, INC. , EDELMAN, Gerald, M. , SPORNS, Olaf , TONONI, Giulio
IPC分类号： G06K09/34
CPC分类号： G06T7/20 , G06N3/049
摘要： Apparatus which segments visual scenes into discrete objects. The apparatus is able to perceptually group the elements corresponding to a coherent figure (A) (1) and to segregate them from the background (3) or from another figure (B). Reentrant signaling among rhythmically active neuronal groups (9) is used to correlate responses along spatially extended contours. The efficacy of the connections is allowed to change on a fast time scale resulting in active reentrant connections which amplify the correlations among neuronal groups (9) and provides the desired segmentation.

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式