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    • 2. 发明公开
    • 이식가능한 전극 배열
    • 可植入电极布置
    • KR20180019757A
    • 2018-02-26
    • KR20187004241
    • 2015-10-07
    • NEUROLOOP GMBH
    • PLACHTA DENNISGIERTHMUHLEN MORTIMERSTIEGLITZ THOMASZENTNER JOSEF
    • A61N1/05A61B5/04A61N1/36
    • A61N1/0556A61B5/04001A61B2562/066A61B2562/164
    • 신경다발에포함된적어도하나의신경섬유를따라전파되는뉴런전기신호의공간-선택적검출및 적어도하나의신경섬유의선택적인전기자극을위한이식가능한전극배열이개시되어있는데, 커프-형방식으로신경다발둘레에설치될수 있는적어도하나의운반체기재를갖고이식된상태에서신결다발을향해배향된직선의원통형운반체기재표면(1')을갖는생체적합성운반체기재(1) 및여기에부착된제1 전극배열(2)을포함하고, 상기운반체기재표면은축 방향범위(a) 및원주방향(U)으로배향된범위를갖고, 원주방향으로배열된적어도두 개의제1 전극표면(4)을각각의경우구비한적어도세 개의제1 전극구조물(3), 및축 방향으로서로이격된적어도두 개의제1 전극스트립(5)을축 방향순서로포함하는상기전극배열은원주방향으로연장되고각각의경우링 형성을취하고, 상기제1 전극스트립은축 방향으로양 면상에적어도 3개의전극구조물을감싸고, 신호검출기및 발생기(6)에연결할수 있거나연결된다. 본발명은신경다발을향하는직선의실린더형운반체기재상에축 방향순서로제1 전극배열(2) 옆에적어도하나의제2 전극배열(7)이배열된다는사실로인해구별되는데, 상기제2 전극배열은 - 원주방향(U)으로연장되고각각의경우링 형상을취하는, 서로축 방향으로이격된적어도두개의제2 전극스트립(8), 및원주방향(U)으로동일하게분포되어배열된적어도두 개의제2 전극표면을각각의경우포함하는적어도두 개의제2 전극스트립(8) 사이에서축 방향으로연장되는적어도하나의제2 전극구조물(13)을포함하고, 제2 전극배열(7)은적어도신호발생기(6)에연결되거나추가의신호발생기(6')에연결된다.
    • 可植入电极装置提供了神经元电信号的空间选择性检测,所述神经元电信号沿着神经束中包含的至少一个神经纤维传播,并且用于选择性电刺激所述至少一个神经纤维,所述至少一个神经纤维包括生物相容性载体基质, 至少一个载体基底区域,其可以被放置在套囊中的神经束的周围并且具有在植入状态下面向神经束的直圆柱形载体基底表面。 载体衬底表面具有轴向延伸部和沿一个方向周向定向的延伸部以及附接到其上的第一电极装置。 该电极装置以轴向顺序包括至少三个第一电极结构和至少两个间隔开的第一电极带,所述至少三个第一电极结构具有沿周向布置的至少两个第一电极表面,所述至少两个间隔开的第一电极带沿周向延伸呈环形 ,其在轴向两侧包围至少三个电极结构。 电极可连接或连接到信号检测器和发生器。
    • 7. 发明申请
    • IMPLANTABLE ASSEMBLY
    • US20170304630A1
    • 2017-10-26
    • US15517922
    • 2015-10-07
    • Neuroloop GmbH
    • Dennis PLACHTAMortimer GIEHRTMUEHLENThomas STIEGLITZJosef ZENTNER
    • A61N1/36A61N1/378A61N1/372A61N1/05
    • An implantable assembly is described for acquisition of neuronal electrical signals at a selected location which propagate along at least one nerve fiber contained in a nerve fiber bundle, as well as for selective electrical stimulation of the at least one nerve fiber, having: an implantable electrode assembly (E) which is disposed on a biocompatible support substrate which can be positioned around the nerve fiber bundle in a cuff, which has a cylindrical support substrate surface (i) which in the implanted condition is orientated facing the nerve fiber bundle, on which a first electrode assembly for locationally selective acquisition of the neuronal electrical signals and selective electrical stimulation of the at least one nerve fiber, and on which a second electrode assembly is disposed to record an ECG signal, and an analysis and control unit (A/S) which can be electrically conductively connected or is connected to the implantable electrode assembly (E), in which the locationally selective acquired neuronal electrical signals as well as the ECG signal can be analyzed in a time-resolved manner such that a neuronal time signal correlated with a physiological parameter, such as blood pressure, can be derived.