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1. 发明申请

WO2010038119A3 DETECTING SLEEP EVENTS USING LOCALIZED BLOOD PRESSURE CHANGES 审中-公开
标题翻译：使用本地化血压变化检测睡眠事件
公开(公告)号：WO2010038119A3
公开(公告)日：2010-06-10
申请号：PCT/IB2009006895
申请日：2009-09-17
申请人： NELLCOR PURITAN BENNETT IRELAN , WATSON JAMES NICHOLAS , ADDISON PAUL STANLEY , SETHI RAKESH
发明人： WATSON JAMES NICHOLAS , ADDISON PAUL STANLEY , SETHI RAKESH
IPC分类号： A61B5/021
CPC分类号： A61B5/021 , A61B5/0059 , A61B5/02125 , A61B5/4809 , A61B5/4812 , A61B5/6816 , A61B5/6826 , A61B5/6829 , A61B5/6838
摘要： Techniques for detecting sleep events are disclosed. In some embodiments, a continuous non-invasive blood pressure ("CNIBP") monitoring system may be used to obtain blood pressure values from a subject during a sleep study. Changes in the blood pressure over time may be determined and analyzed in order to identify a sleep event. The localized blood pressure changes may be interpreted in isolation or in combination with other signals collected from the subject.
摘要翻译：公开了用于检测睡眠事件的技术。在一些实施例中，可以使用连续非侵入性血压（“CNIBP”）监测系统来在睡眠研究期间获得受试者的血压值。可以确定和分析血压随时间的变化，以便识别睡眠事件。局部血压变化可以单独解释或与从受试者收集的其他信号组合解释。

2. 发明申请

WO2010001231A3 PROCESSING AND DETECTING BASELINE CHANGES IN SIGNALS 审中-公开
标题翻译：加工和检测信号中的基线变化
公开(公告)号：WO2010001231A3
公开(公告)日：2010-03-11
申请号：PCT/IB2009006134
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAN , WATSON JAMES NICHOLAS , ADDISON PAUL STANLEY
发明人： WATSON JAMES NICHOLAS , ADDISON PAUL STANLEY
IPC分类号： A61B5/00
CPC分类号： A61B5/7282 , A61B5/0205 , A61B5/14551 , A61B5/1495 , A61B5/6814 , A61B5/6826 , A61B5/6838 , A61B5/726 , G06F19/12 , G06F19/24 , G06F19/26 , G06F19/34 , G16H40/40
摘要： According to embodiments, systems and methods for detecting the occurrence of events from a signal are provided. A signal processing system may analyze baseline changes and changes in signal characteristics to detect events from a signal. The system may also detect events by analyzing energy parameters and artifacts in a scalogram of the signal. Further, the system may detect events by analyzing both the signal and its corresponding scalogram.
摘要翻译：根据实施例，提供了用于检测来自信号的事件的发生的系统和方法。信号处理系统可以分析基线变化和信号特征的变化，以检测来自信号的事件。该系统还可以通过分析信号的标尺中的能量参数和伪像来检测事件。此外，系统可以通过分析信号及其对应的标尺来检测事件。

3. 发明申请

WO2010038121A3 EXTRACTION OF PHYSIOLOGICAL MEASUREMENTS FROM A PHOTOPLETHYSMOGRAPH (PPG) SIGNAL 审中-公开
标题翻译：光学血红蛋白（PPG）信号中生理测量的提取
公开(公告)号：WO2010038121A3
公开(公告)日：2010-07-29
申请号：PCT/IB2009006897
申请日：2009-09-17
申请人： NELLCOR PURITAN BENNETT IRELAN , ADDISON PAUL STANLEY
发明人： ADDISON PAUL STANLEY
IPC分类号： A61B5/00 , G06F17/00
CPC分类号： A61B5/14551 , A61B5/0205 , A61B5/021 , A61B5/024 , A61B5/7239
摘要： The present disclosure relates to signal processing and, more particularly, to determining the value of a physiological parameter, such as the blood oxygen saturation (SpO2) of a subject. In an embodiment, a first baseline for a first waveform and a second baseline for a second waveform are determined. In this embodiment, the first and second waveforms are indicative of the physiological parameter of the subject. The first and second waveforms are filtered to obtain a first direct-current (DC) component for the first waveform and a second DC component for the second waveform. A measured value for the physiological parameter is derived from the first and second baseline signals, and the first and second DC components, hi an embodiment, the measured value for the physiological parameter is determined based on a ratio of the normalized difference between the DC component and the baseline signal for the first waveform with respect to same for the second waveform.
摘要翻译：本公开涉及信号处理，并且更具体地涉及确定生理参数的值，诸如对象的血氧饱和度（SpO2）。在一个实施例中，确定第一波形的第一基线和第二波形的第二基线。在该实施例中，第一和第二波形指示对象的生理参数。对第一和第二波形进行滤波以获得第一波形的第一直流（DC）分量和第二波形的第二DC分量。从第一和第二基线信号以及第一和第二DC分量导出生理参数的测量值。在一个实施例中，生理参数的测量值基于DC分量之间的归一化差的比率来确定以及第一波形的基线信号相对于第二波形的相同。

4. 发明专利

AT424139T 未知
公开(公告)号：AT424139T
公开(公告)日：2009-03-15
申请号：AT02735636
申请日：2002-06-21
申请人： NELLCOR PURITAN BENNETT IRELAN
发明人： ADDISON PAUL , WATSON JAMES NICHOLAS
IPC分类号： A61B5/00 , A61B5/0245 , A61B5/0205 , A61B5/08 , A61B5/145 , G06F17/00 , G06K9/00
摘要： A method of processing a pulse oximetry signal captured using a pulse oximeter, the method comprising decomposing the pulse oximetry signal by wavelet transform analysis, and deriving one or more physiological parameters from the decomposed signal, wherein the decomposed pulse oximetry signal is processed to derive respiration information, in which the respiration information is derived from high amplitude ridges using ridge-following methods and/or by phase methods and/or by cross scale correlation of phase values and/or by analysis of amplitude or frequency modulation.

5. 发明申请

WO2010001233A3 SYSTEMS AND METHODS FOR NON-INVASIVE BLOOD PRESSURE MONITORING 审中-公开
标题翻译：非入血血压监测系统与方法
公开(公告)号：WO2010001233A3
公开(公告)日：2010-04-01
申请号：PCT/IB2009006136
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAN , SETHI RAKESH , WATSON JAMES NICHOLAS
发明人： SETHI RAKESH , WATSON JAMES NICHOLAS
IPC分类号： A61B5/02
CPC分类号： A61B5/021 , A61B5/02125 , A61B5/14551 , A61B5/7239 , A61B5/7278
摘要： According to embodiments, systems and methods for non-invasive blood pressure monitoring are disclosed. A sensor or probe may be used to obtain a plethysmograph or photoplethysmograph (PPG) signal from a subject. From the signal, the time difference between two or more characteristic points in the signal may be computed. The time difference may correspond, for example, to the time for a pulse wave to travel a predetermined distance from the senor or probe to a reflection point and back to the sensor or probe. From this time difference, blood pressure measurements may be computed continuously or on a periodic basis.
摘要翻译：根据实施例，公开了用于非侵入性血压监测的系统和方法。可以使用传感器或探针来获得来自受试者的体积描记器或光电体积描记器（PPG）信号。根据该信号，可以计算信号中两个或更多个特征点之间的时间差。时间差可以对应于例如脉冲波从传感器或探针到反射点行进预定距离并返回到传感器或探针的时间。从该时间差，血压测量可以连续地或周期性地计算。

6. 发明申请

WO2010001246A2 SYSTEMS AND METHODS FOR ARTIFACT DETECTION IN SIGNALS 审中-公开
标题翻译：用于信号检测的系统和方法
公开(公告)号：WO2010001246A2
公开(公告)日：2010-01-07
申请号：PCT/IB2009006180
申请日：2009-06-29
申请人： NELLCOR PURITAN BENNETT IRELAN , WATSON JAMES NICHOLAS , ADDISON PAUL STANLEY
发明人： WATSON JAMES NICHOLAS , ADDISON PAUL STANLEY
CPC分类号： A61B5/14551 , A61B5/04012 , A61B5/7207 , A61B5/726 , G06K9/00516
摘要： According to embodiments, a method and system for artifact detection in signals is disclosed. The artifacts may take the form of movement artifacts in physiological (e.g., pulse oximetry) signals. Artifacts in the wavelet space of the physiological signal may be removed, replaced, ignored, filtered, or otherwise modified by determining the energy within a predefined moving area of the wavelet scalogram, comparing the determined energy within the predefined moving area of the wavelet scalogram to a threshold value, and masking at least one area of artifact in the wavelet scalogram based, at least in part, on the comparison. From the enhanced signal, physiological parameters, for example, respiration, respiratory effort, pulse, and oxygen saturation, may be more reliably and accurately derived or computed.
摘要翻译：根据实施例，公开了一种用于信号中伪影检测的方法和系统。人造物可以采取生理（例如脉搏血氧测定）信号中的运动假象的形式。可以通过确定小波图标的预定移动区域内的能量来比较所确定的小波图示图的预定移动区域内的能量，将小波图形的小波空间中的人造物除以，替换，忽略，滤波或以其它方式进行修改，至少部分地基于该比较来掩蔽小波缩写图中的伪像的至少一个区域。从增强的信号，可以更可靠和准确地导出或计算生理参数，例如呼吸，呼吸力，脉搏和氧饱和度。

7. 发明专利

ES2321282T3 ANALISIS DE SEÑALES DE PULSIOXIMETRIA BASADO EN TREN DE ONDAS. 未知
公开(公告)号：ES2321282T3
公开(公告)日：2009-06-04
申请号：ES02735636
申请日：2002-06-21
申请人： NELLCOR PURITAN BENNETT IRELAN
发明人： ADDISON PAUL STANLEY , WATSON JAMES NICHOLAS
IPC分类号： A61B5/00 , A61B5/0245 , A61B5/0205 , A61B5/08 , A61B5/145 , G06F17/00 , G06K9/00
摘要： Un sistema de medición fisiológica que comprende un pulsioxímetro (10) para obtener una señal de pulsioximetría de un sujeto, y un medio (14) de procesamiento de señales para procesar la señal de pulsioximetría mediante un análisis de transformada de tren de ondas continua para obtener una superficie de energía de transformada de tren de ondas, representar gráficamente la superficie frente a un parámetro de localización y un parámetro de escala e identificar una característica de la superficie representada gráficamente para obtener uno o más parámetros fisiológicos.

8. 发明专利

DE60231399D1 未知
公开(公告)号：DE60231399D1
公开(公告)日：2009-04-16
申请号：DE60231399
申请日：2002-06-21
申请人： NELLCOR PURITAN BENNETT IRELAN
发明人： ADDISON PAUL STANLEY , WATSON JAMES NICHOLAS
IPC分类号： A61B5/00 , A61B5/0245 , A61B5/0205 , A61B5/08 , A61B5/145 , G06F17/00 , G06K9/00
摘要： A method of processing a pulse oximetry signal captured using a pulse oximeter, the method comprising decomposing the pulse oximetry signal by wavelet transform analysis, and deriving one or more physiological parameters from the decomposed signal, wherein the decomposed pulse oximetry signal is processed to derive respiration information, in which the respiration information is derived from high amplitude ridges using ridge-following methods and/or by phase methods and/or by cross scale correlation of phase values and/or by analysis of amplitude or frequency modulation.

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