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1. 发明申请

WO2007002343A2 NOVEL SYSTEM FOR SYNTHESIS OF DEVICE FORMING MONOMERS 审中-公开
标题翻译：用于合成装置形成单体的新型系统
公开(公告)号：WO2007002343A2
公开(公告)日：2007-01-04
申请号：PCT/US2006/024396
申请日：2006-06-21
申请人： BAUSCH & LOMB INCORPORATED , NANDU, Mahendra , FRIENDS, Gary, D. , SEELYE, David, E. , KANSAL, Vinod, Kumar , SHAH, C. C. , MISTRY, Dharmesh, Balvantrai
发明人： NANDU, Mahendra , FRIENDS, Gary, D. , SEELYE, David, E. , KANSAL, Vinod, Kumar , SHAH, C. C. , MISTRY, Dharmesh, Balvantrai
IPC分类号： C07C68/06 , C07F7/18 , C07C269/04 , C07C69/96 , C07C271/22
CPC分类号： C07F7/0889 , C07C68/06 , C07C269/04 , C07C69/96 , C07C271/22
摘要： Disclosed in embodiments herein is a method of synthesizing device forming monomers using N-(Vinyloxycarbonyloxy) succinimide.
摘要翻译：在本文的实施方案中公开的是使用N-（乙烯氧基羰基氧基）琥珀酰亚胺合成装置形成单体的方法。

2. 发明申请

WO2005065734A1 SURFACE TREATMENT UTILIZING SUPERCRITICAL FLUID 审中-公开
标题翻译：表面处理利用超临界流体
公开(公告)号：WO2005065734A1
公开(公告)日：2005-07-21
申请号：PCT/US2004/041048
申请日：2004-12-09
申请人： BAUSCH & LOMB INCORPORATED , AMMON, Daniel, M., Jr. , SALAMONE, Joseph, C. , NANDU, Mahendra
发明人： AMMON, Daniel, M., Jr. , SALAMONE, Joseph, C. , NANDU, Mahendra
IPC分类号： A61L27/34
CPC分类号： A61L27/50 , A61L27/34 , G02B1/043 , C08L83/04 , C08L33/02 , C08L51/085
摘要： This invention provides a method of modifying the surface of a medical device, such as an ophthalmic lens. The method involves contacting a surface of the medical device with a surface modifying agent in the presence of supercritical fluid. The device may be constructed of materials such as hydrogel copolymers and silicone materials.
摘要翻译：本发明提供一种改变诸如眼科镜片的医疗装置的表面的方法。该方法包括在超临界流体存在下使医疗装置的表面与表面改性剂接触。该装置可以由诸如水凝胶共聚物和硅氧烷材料的材料构成。

3. 发明申请

WO2007002343A3 NOVEL SYSTEM FOR SYNTHESIS OF DEVICE FORMING MONOMERS 审中-公开
标题翻译：合成器件形成单体的新体系
公开(公告)号：WO2007002343A3
公开(公告)日：2007-04-26
申请号：PCT/US2006024396
申请日：2006-06-21
申请人： BAUSCH & LOMB , NANDU MAHENDRA , FRIENDS GARY D , SEELYE DAVID E , KANSAL VINOD KUMAR , SHAH C C , MISTRY DHARMESH BALVANTRAI
发明人： NANDU MAHENDRA , FRIENDS GARY D , SEELYE DAVID E , KANSAL VINOD KUMAR , SHAH C C , MISTRY DHARMESH BALVANTRAI
IPC分类号： C07C68/06 , C07C69/96 , C07C269/04 , C07C271/22 , C07F7/18 , G02B1/04
CPC分类号： C07F7/0889 , C07C68/06 , C07C269/04 , C07C69/96 , C07C271/22
摘要： Disclosed in embodiments herein is a method of synthesizing device forming monomers using N-(Vinyloxycarbonyloxy) succinimide.
摘要翻译：本文的实施方式公开了使用N-（乙烯氧基羰氧基）琥珀酰亚胺合成装置形成单体的方法。

4. 发明申请

WO2006069207A1 PRE-POLYMER EXTRACTION USING A SUPER-COOLED FLUID 审中-公开
标题翻译：使用超级冷却液的预聚物提取
公开(公告)号：WO2006069207A1
公开(公告)日：2006-06-29
申请号：PCT/US2005/046515
申请日：2005-12-21
申请人： BAUSCH & LOMB INCORPORATED , RASTOGI, Sanjay , NANDU, Mahendra , FRIENDS, Gary
发明人： RASTOGI, Sanjay , NANDU, Mahendra , FRIENDS, Gary
IPC分类号： B29D11/00 , B29C71/00
CPC分类号： B29D11/00201 , B29C71/0009 , B29C2071/0027 , B29D11/00038 , B29D11/00067 , B29L2011/0041
摘要： The present invention is a process for extracting pre-polymer from a polymer lens. The process comprises the step of contacting the lens with a super-cooled solvent for a period of time sufficient to extract pre-polymer from the polymer lens.
摘要翻译：本发明是从高分子透镜中提取预聚物的方法。该方法包括使透镜与超冷却溶剂接触足以从聚合物透镜提取预聚物的时间的步骤。

5. 发明申请

WO2005113028A1 PROCESS FOR EXTRACTING BIOMEDICAL DEVICES 审中-公开
标题翻译：提取生物医学装置的方法
公开(公告)号：WO2005113028A1
公开(公告)日：2005-12-01
申请号：PCT/US2005/017371
申请日：2005-05-17
申请人： BAUSCH & LOMB INCORPORATED , STAFFORD, Ulick , RASTOGI, Sanjay , NANDU, Mahendra , APPLETON, William
发明人： STAFFORD, Ulick , RASTOGI, Sanjay , NANDU, Mahendra , APPLETON, William
IPC分类号： A61L12/04
CPC分类号： C08J7/02 , A61L27/18 , B01D11/0215 , B01D11/0284 , B01D11/0288 , B29C71/00 , B29C71/0009 , B29C2071/0027 , B29D11/00038 , B29L2011/0041 , C08L83/04
摘要： A process for treating biomedical devices, especially contact lenses, involves contacting polymeric devices containing extractables with a solvent that dissolves and removes the extractables from the devices. The devices are subjected to at least two treatments with solvent to remove extractables in the devices. One of the treatment steps involves solvent used as a final rinse for a prior batch of devices. The solvent may be circulated through a series of tanks, in which case the devices are first extracted in the downstream tanks, followed by extraction in the first tank containing fresh incoming solvent.
摘要翻译：用于治疗生物医学装置，特别是隐形眼镜的方法涉及使包含可萃取物的聚合物装置与溶解并从装置中除去可提取物的溶剂接触。用溶剂对装置进行至少两次处理以除去装置中的可提取物。其中一个处理步骤涉及用作先前批次装置的最终冲洗液的溶剂。溶剂可以循环通过一系列罐，在这种情况下，装置首先在下游罐中提取，然后在含有新鲜进料溶剂的第一罐中萃取。

6. 发明申请

WO2004091883A1 METHOD FOR THE MANUFACTURE OF MOLDED POLYMERIC ARTICLES USING VARIABLE FREQUENCY MICROWAVES 审中-公开
标题翻译：使用可变频率微波制造模制聚合物制品的方法
公开(公告)号：WO2004091883A1
公开(公告)日：2004-10-28
申请号：PCT/US2004/009621
申请日：2004-03-29
申请人： BAUSCH & LOMB INCORPORATED , NANDU, Mahendra , WRUE, Richard, J. , INDRA, Eric, M.
发明人： NANDU, Mahendra , WRUE, Richard, J. , INDRA, Eric, M.
IPC分类号： B29C35/02
CPC分类号： G02B1/043 , B29C35/0288 , B29C35/08 , B29C35/0805 , B29C37/006 , B29C2035/0855 , B29D11/00134 , B29D11/00442 , B29D11/023 , B29K2105/0002 , B29L2011/0041
摘要： The present invention relates to an improved method of manufacture of molded polymeric devices using variable frequency microwaves. Molded polymeric devices include, for example, contact lenses, corneal rings, intraocular lenses and drug delivery devices such as anterior or posterior chamber inserts. Contact lenses include soft and rigid gas permeable contact lenses as well as, lens blanks lathed into finished contact lenses. Molded polymeric devices further include medical devices such as prosthetics including hip joints. According to the present invention, a mold (2) having a cavity the shape of the desired molded polymeric device, the cavity containing a composition comprising one or several monomers having double polymerizable bonds, is placed in a microwave chamber (8). The mold (2) can be plastic, glass, ceramic or metal. Plastic is preferred. The mold (2) is then swept with at least one range of microwave frequencies to polymerize the composition, thus forming the molded polymeric device. A range of frequencies includes a central frequency selected to rapidly heat the composition. A range is selected to generate a plurality of modes within the chamber (6). Sweeping is performed at a rate selected to avoid damage to the polymer formed and the mold (2).
摘要翻译：本发明涉及使用可变频率微波制造模制聚合物的改进方法。模制聚合物装置包括例如隐形眼镜，角膜环，眼内透镜和药物递送装置，例如前腔或后房插入物。隐形眼镜包括柔软和刚性透气的隐形眼镜以及车床成型隐形眼镜的镜片毛坯。模制的聚合物装置还包括诸如假肢的医疗装置，包括髋关节。根据本发明，将具有所需模制聚合物装置形状的空腔的空腔（2）放置在微波室（8）中，所述模腔（2）包含含有一个或多个具有双重可聚合键的单体的组合物。模具（2）可以是塑料，玻璃，陶瓷或金属。塑料是首选。然后用至少一个微波频率范围扫描模具（2）以聚合组合物，从而形成模制的聚合物装置。频率范围包括选择的快速加热组合物的中心频率。选择范围以在腔室（6）内产生多个模式。以选择的速率进行扫描，以避免损坏形成的聚合物和模具（2）。

7. 发明申请

WO2006036793A1 METHOD FOR POLYMERIZING OPHTHALMIC DEVICES 审中-公开
标题翻译：聚合光学器件的方法
公开(公告)号：WO2006036793A1
公开(公告)日：2006-04-06
申请号：PCT/US2005/034160
申请日：2005-09-22
申请人： BAUSCH & LOMB INCORPORATED , RASTOGI, Sanjay , HENNING, Charles, P. , NANDU, Mahendra, P.
发明人： RASTOGI, Sanjay , HENNING, Charles, P. , NANDU, Mahendra, P.
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , B29D11/00134
摘要： A method involves providing a monomer mixture comprising a biomedical device-forming monomer and a UV absorbing agent; and exposing the monomer mixture to an electron beam to cure the monomer mixture.
摘要翻译：一种方法包括提供包含生物医学装置形成单体和UV吸收剂的单体混合物; 并将单体混合物暴露于电子束以固化单体混合物。

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