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1. 发明申请

WO0178748A2 IMMUNOMODULATORY METHODS USING CARBOHYDRATE ANTIGENS 审中-公开
标题翻译：使用碳水化合物抗原的免疫组织化学方法
公开(公告)号：WO0178748A2
公开(公告)日：2001-10-25
申请号：PCT/US0112365
申请日：2001-04-16
申请人： HARVARD COLLEGE , HARN DONALD A , MITSUHIRO OKANO , TERRAZAS LUIS IGNACIO
发明人： HARN DONALD A , MITSUHIRO OKANO , TERRAZAS LUIS IGNACIO
IPC分类号： A61K31/726 , A61K39/385 , A61K47/48 , A61P37/00 , A61K31/702
CPC分类号： A61K31/726 , A61K39/385 , A61K47/61 , A61K47/643 , A61K2039/57 , A61K2039/6081 , A61K2039/6087
摘要： Methods for modulating immune responses, such as IgE responses and autoimmune responses, are provided. The methods involve contacting a cell with an agent comprising multivalent lacto-N-neotetraose (LNnT), which modulates an immune response. The methods are useful for enhancing production of non-specific polyclonal IgE, inhibiting production of antigen-specific IgE responses, inducing cytokine production, and stimulating proliferation of splenocytes. In a preferred embodiment, the invention provides methods for modulating an immune response to an antigen (e.g., an allergan) in vivo . Pharmaceutical compositions for modulating immune responses comprising the agents of the invention are also provided. The invention also provides for treatment or prevention of shock in a subject using multivalent LNnT and methods for treating an autoimmune disease in a subject using multivalent LNnT. Still further the invention provides for treatment of cancer in a subject using monovalent LNnT.
摘要翻译：提供了调节免疫应答的方法，如IgE反应和自身免疫应答。所述方法包括使细胞与包含调节免疫应答的多价乳-N-新四糖（LNnT）的试剂接触。该方法可用于增强非特异性多克隆IgE的产生，抑制抗原特异性IgE应答的产生，诱导细胞因子产生和刺激脾细胞增殖。在优选的实施方案中，本发明提供了在体内调节对抗原（例如，allergan）的免疫应答的方法。还提供了用于调节包含本发明的药剂的免疫应答的药物组合物。本发明还提供使用多价LNnT治疗或预防受试者的休克以及使用多价LNnT治疗受试者的自身免疫性疾病的方法。本发明进一步提供了使用单价LNnT治疗受试者的癌症。

2. 发明授权

US4879491A Electric lamp assembly 失效
标题翻译：电灯组件
公开(公告)号：US4879491A
公开(公告)日：1989-11-07
申请号：US215537
申请日：1988-07-06
申请人： Yasuo Hirozumi , Susumu Kanematsu , Yasuyoshi Numajiri , Mikio Watanabe , Mitsuhiro Okano
发明人： Yasuo Hirozumi , Susumu Kanematsu , Yasuyoshi Numajiri , Mikio Watanabe , Mitsuhiro Okano
IPC分类号： H01K1/46 , F21V19/00
CPC分类号： F21S48/1109
摘要： An electric lamp assembly is disclosed which comprises a bulb unit including a filament, lead lines extending from the filament to the outside of the bulb unit and a hermetic seal portion, the lead lines extending through the hermetic seal portion; a bulb holder including a looped band portion which gripps the hermetic seal portion of the bulb unit having leading ends of the lead lines projected outward from the bulb holder, the bulb holder having foot portions each being formed with at least one opening; and a base assembly including a circular body part, a pair of conducting plate members having leading ends projected outward from respective slits formed in the body part and a plurality of supporting pins extending outward from the body part. The supporting pins are inserted into the openings of the foot portions of the bulb holder and welded to the foot portions to achieve a tight connection between the base assembly and the bulb holder. In order to facilitate mating between the leading ends of the lead wires and the leading ends of the conducting plate members, there is further employed a guide structure which guides the leading ends of the lead wires to give portions of the conducting plate members upon coupling of the bulb holder and the base assembly.
摘要翻译：公开了一种电灯组件，其包括灯泡单元，灯泡单元包括灯丝，从灯丝延伸到灯泡单元外部的引线和气密密封部分，引出线延伸穿过气密密封部分; 灯头保持器，其包括环状带部分，其夹住具有从灯泡保持器向外突出的引线的前端的灯泡单元的气密密封部分，灯头保持器具有各自形成有至少一个开口的脚部; 以及基部组件，其包括圆形主体部分，一对导电板部件，其具有从形成在主体部分中的各狭缝向外突出的前端部和从主体部分向外延伸的多个支撑销。支撑销插入灯泡保持器的脚部的开口中并焊接到脚部，以实现基座组件和灯座之间的紧密连接。为了促进引线的前端和导电板构件的前端之间的配合，还采用引导结构，引导结构引导导线的前端，以在导电板构件的连接时给出导电板构件的一部分灯座和基座组件。

3. 发明授权

US4864183A Electric lamp assembly having improved mechanical connection between light bulb and molded plastic holder body 失效
标题翻译：电灯组件具有改进的灯泡和模制塑料保持器主体之间的机械连接
公开(公告)号：US4864183A
公开(公告)日：1989-09-05
申请号：US232902
申请日：1988-08-15
申请人： Mitsuhiro Okano
发明人： Mitsuhiro Okano
IPC分类号： H01K1/46 , F21V19/00 , H01R33/94
CPC分类号： F21S48/1109 , H01R33/94
摘要： A lamp assembly having a molded plastic holder body for holding a light bulb in position thereon. The light bulb has a flat base encircled by a holder band which has bulb retainer lugs resiliently engaging the bulb base under their own bias. The holder band inclusive of the bulb retainer lugs is made from a metal (e.g. nickel silver) that is resilient enough to enable the lugs to securely engage the bulb base. Spot welded to the holder band is a first connector made from another metal (e.g. austenitic stainless steels of certain specific compositions) that is weldable enough to permit the first connector to be firmly welded to the holder band. A second connector of substantially tubular shape, which may be made from the same metal as the first connector, is immovably engaged in the holder body and welded to the first connector. Thus the light bulb is securely engaged by the holder band of resilient metal and firmly mechanically coupled to the molded plastic holder body via the first and second connectors of weldable metal.
摘要翻译：一种灯组件，其具有用于将灯泡保持在其上的位置的模制塑料保持器主体。灯泡具有由保持带包围的扁平底座，其具有在其自身偏压下弹性地接合灯泡基座的灯泡保持器突出部。包括灯泡保持器凸耳的保持器带由金属（例如镍银）制成，其具有足够的弹性，以使凸耳牢固地接合灯泡基座。点焊到保持带是由另一种金属（例如某些特定组成的奥氏体不锈钢）制成的第一连接器，其可焊接足以允许第一连接器牢固地焊接到保持带上。基本上管状形状的第二连接器可以由与第一连接器相同的金属制成，不可移动地接合在保持器主体中并焊接到第一连接器。因此，灯泡通过弹性金属的保持带牢固地接合并且经由可焊接金属的第一和第二连接器牢固地机械耦合到模制塑料保持器本体。

4. 发明授权

US06525450B2 Bulb applied with a glare protection paint and a vehicular lighting fixture equipped therewith 失效
标题翻译：灯泡应用有防眩光保护漆和配备其的车辆照明灯具
公开(公告)号：US06525450B2
公开(公告)日：2003-02-25
申请号：US09737495
申请日：2000-12-14
申请人： Koichi Nakamura , Kiyoshi Yazaki , Mitsuhiro Okano , Hitoshi Hemmi
发明人： Koichi Nakamura , Kiyoshi Yazaki , Mitsuhiro Okano , Hitoshi Hemmi
IPC分类号： H01J516
CPC分类号： H01J61/40 , F21S41/14
摘要： A vehicular bulb with its front end coated with a glare-protection paint that contains silicon carbide (SiC) as its pigment substance. With this silicon carbide contained paint, the front end externally assumes a color that is substantially the same color as reflectors and is thus prevented from being easily recognized from the outside of a lighting fixture that is installed with such a bulb.
摘要翻译：其前端涂有防护涂料的车灯，其中含有碳化硅（SiC）作为其颜料。在该碳化硅含有涂料的情况下，前端外部呈现与反射体基本上相同的颜色的颜色，从而防止从安装有这种灯泡的照明器具的外部容易地识别。

5. 发明授权

US5043624A Electric lamp assembly having a band connected to integrally formed metal pieces on a base 失效
标题翻译：电灯组件，其具有与底座上的整体形成的金属片连接的带
公开(公告)号：US5043624A
公开(公告)日：1991-08-27
申请号：US442977
申请日：1989-11-29
申请人： Yasuo Hirozumi , Mitsuhiro Okano
发明人： Yasuo Hirozumi , Mitsuhiro Okano
IPC分类号： F21V17/00 , H01K1/46
CPC分类号： F21S48/155 , H01K1/46
摘要： An electric lamp assembly comprising a lamp bulb a lamp base being essentially formed of a synthetic resin material and a retaining band being made of a metal. A plurality of weldable supporting pieces formed of a metal are integrally formed on the lamp base by insert forming process with the front end portions of the supporting pieces projecting out of the front end portion of the lamp base. A plurality of mounting openings are formed in the retaining band. Respective front end portions of the supporting pieces are inserted through the mounting openings in the retaining band and are welded to edges of the mounting openings respectively.
摘要翻译：一种电灯组件，包括灯泡，基本上由合成树脂材料形成的灯座和由金属制成的保持带。由金属制成的多个可焊接支撑件通过插入成形工艺一体地形成在灯座上，其中支撑件的前端部突出到灯座的前端部分之外。在保持带中形成多个安装开口。支撑件的前端部分分别穿过保持带中的安装开口插入并分别焊接到安装孔的边缘。

6. 发明授权

US07558471B2 Video recording apparatus and method, and video output apparatus and method 失效
标题翻译：视频记录装置和方法以及视频输出装置和方法
公开(公告)号：US07558471B2
公开(公告)日：2009-07-07
申请号：US10822084
申请日：2004-04-08
申请人： Yukio Yanagihara , Yoshinori Shimizu , Mitsuhiro Okano
发明人： Yukio Yanagihara , Yoshinori Shimizu , Mitsuhiro Okano
IPC分类号： H04N7/26 , H04N5/91
CPC分类号： H04N9/8042 , H04N5/85 , H04N9/7921
摘要： A DVD recorder is provided which includes an NTSC decoder (15) for converting an NTSC-based TV signal into an ITU-R BT. 601-based video signal, an MPEG encoder (17) for encoding the ITU-R BT. 601-based video signal into an MPEG-2 data stream, a driver (23) for recording the MPEG-2-based data stream to a DVD disk, and a VBI slice circuit (24) for detecting VBI from the TV signal. When the V timing of an input signal is asynchronous with that of recording signal, the MPEG encoder (17) inserts null data as blanking data into an arbitrary frame if a frame repeat has occurred or deletes null data from blanking data from an arbitrary frame if a frame skip has occurred.
摘要翻译：提供了一种DVD记录器，其包括用于将基于NTSC的TV信号转换成ITU-R BT的NTSC解码器（15）。 601视频信号，用于对ITU-R BT进行编码的MPEG编码器（17）。 601的视频信号转换为MPEG-2数据流，用于将基于MPEG-2的数据流记录到DVD盘的驱动器（23）和用于从TV信号检测VBI的VBI限幅电路（24）。当输入信号的V定时与记录信号的V定时异步时，MPEG编码器（17）将空数据作为消隐数据插入到任意帧中，如果发生帧重复，或者从任意帧的消隐数据中删除空数据，if 发生了帧跳过。

7. 发明申请

US20120066406A1 REPRODUCTION DEVICE, REPRODUCTION METHOD, AND PROGRAM 审中-公开
标题翻译：复制设备，复制方法和程序
公开(公告)号：US20120066406A1
公开(公告)日：2012-03-15
申请号：US13208744
申请日：2011-08-12
申请人： Mitsuhiro Okano , Hiroaki Hashiguchi , Hiroaki Tano
发明人： Mitsuhiro Okano , Hiroaki Hashiguchi , Hiroaki Tano
IPC分类号： G06F15/16
CPC分类号： H04N21/44004 , H04L65/604 , H04N21/433 , H04N21/4542
摘要： A reproduction device includes a reception unit that receives content data through a network in a streaming manner; a discrimination unit that discriminates reproduction data to reproduce and non-reproduction data not to reproduce in the content data received in the streaming manner by the reception unit; a data managing unit that stores the reproduction data in a buffer and does not store the non-reproduction data in the buffer, with respect to the reproduction data and the non-reproduction data discriminated by the discrimination unit; and a decoding unit that decodes the reproduction data stored in the buffer by the data managing unit.
摘要翻译：再现装置包括：以流式方式通过网络接收内容数据的接收单元; 识别单元，用于识别再现数据以及不由再现的非再现数据;以及接收单元以流式传输方式接收的内容数据; 数据管理单元，用于将再现数据存储在缓冲器中，并且不将非再现数据存储在缓冲器中;对于由识别单元识别的再现数据和非再现数据; 以及解码单元，其通过数据管理单元对存储在缓冲器中的再现数据进行解码。

8. 发明授权

US4769574A Incandescent lamp with a metal coupling to a plastic lamp base for automotive headlamp and like lighting applications 失效
标题翻译：白炽灯与金属耦合到塑料灯座用于汽车前照灯和照明应用
公开(公告)号：US4769574A
公开(公告)日：1988-09-06
申请号：US83948
申请日：1987-08-04
申请人： Masakazu Nagasawa , Mitsuhiro Okano
发明人： Masakazu Nagasawa , Mitsuhiro Okano
IPC分类号： H01K1/46 , H01J5/14
CPC分类号： H01K1/46
摘要： For coupling a halogen incandescent lamp to a plastic lamp base in correct positional relationship, a sheet-metal lamp holder is rigidly engaged with a hermetic end seal of the lamp, and a sheet-metal sleeve is anchored in the lamp base. The sleeve has several connecting fingers extending therefrom for somewhat loose engagement in openings in the lamp holder. The loose engagement of the sleeve fingers in the lamp holder openings permit adjustment of the positions of the lamp and the lamp base, which are secured respectively to the lamp holder and to the lamp base, with respect to each other. The sleeve fingers are welded to the lamp holder following the adjustment of the positional relationship between the lamp and the lamp holder.
摘要翻译：为了将卤素白炽灯以正确的位置关系耦合到塑料灯座，金属灯座与灯的密封端密封件刚性地接合，并且金属片套筒固定在灯座中。套筒具有几个从其延伸的连接指状物，用于稍微松动地接合在灯座中的开口中。套管指在灯座开口中的松动接合允许调节相对于彼此分别固定到灯座和灯座的灯和灯座的位置。在调节灯和灯座之间的位置关系的情况下，套筒指状物焊接到灯座上。

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