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1. 外观设计

USD695943S1 LED wallwash 有权
标题翻译： LED洗墙灯
公开(公告)号：USD695943S1
公开(公告)日：2013-12-17
申请号：US29428203
申请日：2012-07-27
申请人： Jean-Francois Duquette , Michel Fortin , Guy Galipeau , Etienne Dansereau , Jonathan Hardy , Jean-François Laporte , Pascal Pavao , Marc-Antoine Vachon
设计人： Jean-Francois Duquette , Michel Fortin , Guy Galipeau , Etienne Dansereau , Jonathan Hardy , Jean-François Laporte , Pascal Pavao , Marc-Antoine Vachon

2. 发明授权

US5985894A N-substituted quinolines 失效
标题翻译： N-取代喹啉
公开(公告)号：US5985894A
公开(公告)日：1999-11-16
申请号：US964182
申请日：1997-11-04
申请人： Fran.cedilla.ois Clemence , Michel Fortin , Jean-Luc Haesslein
发明人： Fran.cedilla.ois Clemence , Michel Fortin , Jean-Luc Haesslein
IPC分类号： A61K31/435 , A61K31/47 , A61K31/495 , A61K31/50 , A61K31/502 , A61K31/505 , A61P1/00 , A61P1/04 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P13/02 , A61P15/00 , A61P15/02 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , A61P27/02 , A61P43/00 , C07D215/22 , C07D215/233 , C07D215/36 , C07D215/48 , C07D237/28 , C07D401/10 , C07D401/14 , C07D471/04
CPC分类号： C07D215/233 , C07D215/36 , C07D215/48 , C07D237/28 , C07D401/10 , C07D401/14 , C07D471/04
摘要： Novel N-substituted quinolines of the formula useful in the treatment of cardiovascular illnesses having an alteration in the vasomotricity and a process for their preparation.
摘要翻译：用于治疗血管活性改变的心血管疾病的新型N-取代喹啉及其制备方法。

3. 发明授权

US5942622A Acid pyrazole derivatives, preparation method therefor, use thereof as drugs, novel use therefor, and pharmaceutical compositions containing such derivatives 失效
标题翻译：酸性吡唑衍生物及其制备方法，作为药物的用途，其新用途，含有该衍生物的药物组合物
公开(公告)号：US5942622A
公开(公告)日：1999-08-24
申请号：US43094
申请日：1998-04-22
申请人： Stanislas Didierlaurent , Michel Fortin , Jidong Zhang
发明人： Stanislas Didierlaurent , Michel Fortin , Jidong Zhang
IPC分类号： A61K31/00 , A61K31/415 , A61K31/4155 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/4439 , A61P9/00 , A61P11/00 , A61P11/06 , A61P43/00 , C07D405/06 , C07D405/14 , C07D409/14 , C07D401/04 , C07D231/18 , C07D257/04
CPC分类号： C07D405/06 , C07D405/14 , C07D409/14
摘要： The subject of the invention is the products of formula (I): in which one of A and B represents a nitrogen atom and the other one of A and B represents a methine radical, such that:A represents either nitrogen substituted in particular by alkyl,or methine substituted in particular by phenyl, thienyl or pyridyl,B represents either nitrogen substituted in particular by cyclohexylalkyl,or methine substituted in particular by alkylthio,R.sub.1 represents in particular carboxy,R represents in particular halogen,as well as the isomers and salts of said products of formula(I).
摘要翻译： PCT No.PCT / FR96 / 01615 Sec。 371日期：1998年4月22日 102（e）1998年4月22日PCT PCT 1996年10月16日PCT公布。出版物WO97 / 15570 日期1997年5月1日本发明的主题是式（I）的产物：其中A和B中的一个表示氮原子，A和B中的一个表示次甲基，使得：A表示氮取代特别是烷基或次甲基，特别是被苯基，噻吩基或吡啶基取代，B代表特别是被环己基烷基取代的氮或特别由烷硫基取代的次甲基，R 1特别表示羧基，R表示特别是卤素，以及所述式（I）产物的异构体和盐。

4. 发明授权

US5691347A Method for inhibiting vasoconstriction 失效
标题翻译：抑制血管收缩的方法
公开(公告)号：US5691347A
公开(公告)日：1997-11-25
申请号：US425365
申请日：1995-04-20
申请人： Alain Corbier , Michel Fortin , Jacques Guillaume , Jean-Luc Haesslein , Jean-Paul Vevert
发明人： Alain Corbier , Michel Fortin , Jacques Guillaume , Jean-Luc Haesslein , Jean-Paul Vevert
IPC分类号： A61K31/435 , A61P9/10 , A61P9/12 , A61P11/06 , A61P13/12 , A61P15/00 , A61P25/28 , A61P27/06 , A61P43/00 , C07D471/04 , C07F3/06
CPC分类号： C07D471/04 , C07F3/06
摘要： The bicyclic derivatives of pyridines of the formula ##STR1## and their non-toxic, pharmaceutically acceptable salts and a process and intermediates for their preparation which compounds are inhibitors of angiotensin II effects, particularly a vasoconstrictor activity.
摘要翻译：下式的吡啶的双环衍生物及其无毒的药学上可接受的盐及其制备方法和中间体，其中化合物是血管紧张素II作用的抑制剂，特别是血管收缩剂活性。

5. 发明授权

US5234944A Novel indanes 失效
标题翻译：新的indanes
公开(公告)号：US5234944A
公开(公告)日：1993-08-10
申请号：US970776
申请日：1992-11-03
申请人： Francois Clemence , Odile Le Martret , Francoise Delevallee , Michel Fortin
发明人： Francois Clemence , Odile Le Martret , Francoise Delevallee , Michel Fortin
IPC分类号： C07D295/135 , C07D311/96
CPC分类号： C07D295/135 , C07D311/96
摘要： A compound selected from the group consisting of enantiomers and diastereoisomer forms and mixtures thereof of the formula ##STR1## wherein R.sub.6 is selected from the group consisting of hydrogen, halogen and alkyl and alkoxy of 1 to 5 carbon atoms, R.sub.1 and R.sub.2 are individually hydrogen or alkyl of 1 to 5 carbon atoms or taken together with the carbon atoms to which they are attached form a cycloalkyl of 3 to 6 carbon atoms optionally containing a heteroatom selected from the group consisting of --S--, --O-- and --N--, one of A and B has the formula ##STR2## and the other has the formula ##STR3## R is selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, Z is selected from the group consisting of --(CH.sub.2).sub.n --, branched alkylene of 2 to 8 carbon atoms and --CH.sub.2 O--, n is an integer of 0 to 5, X, X' and X" are individually selected from the group consisting of hydrogen, alkyl and alkoxy of 1 to 4 carbon atoms, halogen, --OH, --CF.sub.3, --NO.sub.2, --NH.sub.2, mono and dialkylamino of 1 to 4 alkyl carbon atoms and sulfamino, R.sub.3 and R.sub.4 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms or taken together with the nitrogen atom to which they are attached form a 5 to 6 member heterocycle optionally containing a member of the group consisting of --O--, --S-- and ##STR4## R.sub.1 ' is hydrogen or alkyl of 1 to 4 carbon atoms and their non-toxic, pharmaceutically acceptable acid addition salts having a strong affinity for optical receptors, central analgesic, diuretic, anti-arrythmic, hypotensive and cerebral anti-ischemic activity.
摘要翻译：选自下组的对映异构体和非对映异构体形式的化合物及其混合物，其中R 6选自氢，卤素和1至5个碳原子的烷基和烷氧基，R 1和R 2分别为氢或1至5个碳原子的烷基或与它们所连接的碳原子一起形成3至6个碳原子的环烷基，任选地含有选自-S - ， - O-和-N - ，A和B中的一个具有式，另一个具有式（Ia）的化合物，其选自氢和1至5个碳原子的烷基，Z选自 - （ CH 2）n支链亚烷基，-CH 2 O-，n为0〜5的整数，X，X'和X“分别选自氢，烷基和烷氧基的1 至4个碳原子，卤素，-OH，-CF 3，-NO 2，-NH 2，1至4个烷基的单和二烷基氨基碳原子和磺氨基，R3和R4分别选自氢和1至5个碳原子的烷基，或与它们所连接的氮原子一起形成5至6个成员杂环，任选地含有由-O-，-S-和R IMA'组成的基团是氢或1至4个碳原子的烷基，它们对光学受体具有强亲和力的无毒的药学上可接受的酸加成盐，中枢性镇痛药，利尿剂，抗焦虑，降压和脑抗缺血活性。

6. 发明授权

US4988727A N-(aminoindanyl)amides as analgesics and antiarrhythmics 失效
标题翻译： N-（氨基茚满基）酰胺作为镇痛药和抗心律失常药
公开(公告)号：US4988727A
公开(公告)日：1991-01-29
申请号：US409048
申请日：1989-09-19
申请人： Francois Clemence , Michel Fortin
发明人： Francois Clemence , Michel Fortin
IPC分类号： C07D295/135 , C07D295/155 , C07D333/24 , C07D333/54
CPC分类号： C07D295/135 , C07D295/155 , C07D333/24 , C07D333/54
摘要： A compound selected from the group consisting of all enantiomeric and diastereoisomeric forms possible of compounds of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, halogen, and alkyl and alkoxy of 1 to 5 carbon atoms, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, one of A and B being ##STR2## and the other being ##STR3## R is hydrogen or alkyl of 1 to 5 carbon atoms, Z is --(CH.sub.2).sub.n -- or branched alkylene of 2 to 8 carbon atoms, n is an integer from 0 to 5, Y is selected from the group consisting of naphthyl, indenyl, heterobicyclics and heteromonocyclic containing 5 to 6 ring members, all optionally substituted with at least one member of the group consisting of alkyl and alkoxy of 1 to 5 carbon atoms, halogen, --OH, --CF.sub.3, --NO.sub.2, --NH.sub.2 monoalkylamino and dialkylamino of 1 to 4 alkyl carbon atoms and phenyl optionally substituted with at least one member of the group consisting of halogen and alkyl and alkoxy of 1 to 4 carbon atoms, R.sub.3 and R.sub.4 are individually hydrogen or alkyl or 1 to 5 carbon atoms or taken together with the nitrogen form a heterocyclic of 5 to 6 ring members and optionally containing --O--, --S-- or nitrogen in the ring and their non-toxic, pharmaceutically acceptable acid addition salts having central analgesic and antiarythmic activity among other activities.
摘要翻译：选自下列化合物的化合物：其中X选自氢，卤素和1至5个碳原子的烷基和烷氧基，R 1和R 2的所有对映异构体和非对映异构体形式。分别选自氢和1至5个碳原子的烷基，A和B之一为“IMAGE”，另一个为R 1为氢或1至5个碳原子的烷基，Z为 - （ CH 2）2至8个碳原子的正或支链亚烷基，n为0至5的整数，Y选自萘基，茚基，异双环烯烃和含有5至6个环成员的杂单环，全部任选被由1至5个碳原子的烷基和烷氧基，卤素，-OH，-CF 3，-NO 2，-NH 2单烷基氨基和1至4个烷基碳原子的二烷基氨基组成的组中的至少一个和任选被至少一个成员取代的苯基由卤素和烷基组成的组中具有1至4个碳原子的烷氧基，R 3和R 4独立地为氢或烷基或1至5个碳原子，或与氮一起形成5至6个环成员的杂环，并任选地含有-O - ， - S-或环中的氮和它们的无毒的药学上可接受的酸加成盐，具有其他活性的中枢镇痛和抗血液活性。

7. 发明授权

US4888355A Indanes and their use as antiarrhythmic agents 失效
标题翻译：吲哚及其作为抗心律不齐剂的用途
公开(公告)号：US4888355A
公开(公告)日：1989-12-19
申请号：US136814
申请日：1987-12-22
申请人： Francois Clemence , Odile Le Martret , Michel Fortin , Francoise Delevallee
发明人： Francois Clemence , Odile Le Martret , Michel Fortin , Francoise Delevallee
IPC分类号： C07D209/42 , A61K31/165 , A61K31/33 , A61K31/34 , A61K31/343 , A61K31/40 , A61K31/403 , A61K31/404 , A61K31/42 , A61K31/423 , A61K31/425 , A61K31/428 , A61K31/47 , A61P3/04 , A61P7/10 , A61P9/00 , A61P9/06 , A61P9/12 , A61P25/04 , A61P25/06 , C07C67/00 , C07C209/00 , C07C209/16 , C07C209/60 , C07C209/62 , C07C211/42 , C07C213/00 , C07C215/44 , C07C217/74 , C07C231/00 , C07C231/02 , C07C233/11 , C07C233/23 , C07C233/41 , C07C233/62 , C07C233/65 , C07C233/74 , C07C233/79 , C07D215/14 , C07D215/48 , C07D235/04 , C07D263/54 , C07D277/64 , C07D295/12 , C07D295/135 , C07D295/155 , C07D307/79 , C07D333/24 , C07D333/54 , C07D403/12
CPC分类号： C07D295/135 , C07D295/155 , C07D333/24 , C07D333/54
摘要： A compound selected from the group consisting of all enantiomeric and diastereoisomeric forms possible of compounds of the formula ##STR1## wherein X is selected from the group consisting of hydrogen, halogen, and alkyl and alkoxy of 1 to 5 carbon atoms, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 5 carbon atoms, one of A and B being ##STR2## and the other being ##STR3## R is hydrogen or alkyl of 1 to 5 carbon atoms, Z is --(CH.sub.2).sub.n -- or branched alkylene of 2 to 8 carbon atoms, n is an integer from 0 to 5, Y is selected from the group consisting of naphthyl, indenyl, heterobicyclics and heteromonocyclic containing 5 to 6 ring members, all optionally substituted with at least one member of the group consisting of alkyl and alkoxy of 1 to 5 carbon atoms, halogen, --OH, --CF.sub.3, --NO.sub.2, --NH.sub.2, monoalkylamino and dialkylamino of 1 to 4 alkyl carbon atoms and phenyl optionally substituted with at least one member of the group consisting of halogen and alkyl and alkoxy of 1 to 4 carbon atoms, R.sub.3 and R.sub.4 are individually hydrogen or alkyl of 1 to 5 carbon atoms or taken together with the nitrogen form a heterocyclic of 5 to 6 ring members and optionally containing --O--, --S-- or nitrogen in the ring and their non-toxic, pharmaceutically acceptable acid addition salts having central analgesic and antiarythmic activity among other activities.
摘要翻译：选自下列化合物的化合物的化合物：其中X选自氢，卤素和1至5个碳原子的烷基和烷氧基，R 1和R 2的所有对映异构体和非对映异构体形式分别选自氢和1至5个碳原子的烷基，A和B之一为“IMAGE”，另一个为R 1为氢或1至5个碳原子的烷基，Z为 - （ CH 2）2至8个碳原子的正或支链亚烷基，n为0至5的整数，Y选自萘基，茚基，异双环烯烃和含有5至6个环成员的杂单环，全部任选被由1至5个碳原子的烷基和烷氧基，卤素，-OH，-CF 3，-NO 2，-NH 2，1至4个烷基碳原子的一烷基氨基和二烷基氨基组成的组中的至少一个和任选被至少一个由卤素和卤素组成的组的成员具有1至4个碳原子的烷基和烷氧基，R 3和R 4分别是氢或1至5个碳原子的烷基或与氮一起形成5至6个环成员的杂环，并任选地含有-O - ， - S-或环中的氮和它们的无毒的药学上可接受的酸加成盐，具有其他活性的中枢镇痛和抗血液活性。

8. 发明授权

US08536542B2 Flow cytometry analysis across optical fiber 有权
标题翻译：跨光纤的流式细胞术分析
公开(公告)号：US08536542B2
公开(公告)日：2013-09-17
申请号：US12936609
申请日：2010-04-13
申请人： Michel Fortin , Alain Chandonnet , Claude Pare
发明人： Michel Fortin , Alain Chandonnet , Claude Pare
IPC分类号： G01N21/64 , G02B6/42
CPC分类号： G01N21/645 , G01N15/1436 , G01N15/1459 , G01N21/51 , G01N21/6428 , G01N2015/1006 , G01N2021/4707 , G01N2021/4726 , G01N2021/6421 , G01N2021/6439 , G01N2021/6441 , G01N2021/6482 , G01N2021/6484
摘要： An apparatus and method for analyzing a fluid with particle analytes, where the fluid is fed through a passageway within an optical fiber and excitation light is guided by the optical fiber across the passageway and intersects the fluid therein. The optical core is made multimode and is adapted to shape the excitation light with a uniform spatial illumination over a cross-section of the optical core and the passageway is configured relative to the optical core such that the particle analytes are exposed to substantially equal excitation light while circulating in the passageway.
摘要翻译：一种用于分析具有颗粒分析物的流体的装置和方法，其中流体通过光纤内的通道进给，并且激发光由光纤引导通过通道并与其中的流体相交。光芯被制成多模并且适于在光学核心的横截面上以均匀的空间照明来形成激发光，并且该通道相对于光学核心构造，使得颗粒分析物暴露于基本相等的激发光同时在通道中循环。

9. 发明授权

US08021027B2 LED based acorn style luminaire 有权
标题翻译：基于LED的橡胶式灯具
公开(公告)号：US08021027B2
公开(公告)日：2011-09-20
申请号：US12205568
申请日：2008-09-05
申请人： Guy Galipeau , Michel Fortin , Jean-Francois Laporte , Jonathan Hardy
发明人： Guy Galipeau , Michel Fortin , Jean-Francois Laporte , Jonathan Hardy
IPC分类号： F21S8/00
CPC分类号： F21V29/70 , F21S8/088 , F21Y2115/10
摘要： A conventional acorn style globe is described incorporating the utilization of LED's as an illumination source. A supporting heat dissipation plate is provided which extends to the exterior periphery of the acorn style luminaire allowing heat to transfer from the LED's directly to the exterior of the acorn style luminaire while maintaining the integrity of an acorn style globe construction. A plurality of individually orientable lenses on each of the LED's positioned within the interior of the globe allow for efficient downlight and desirable optical characteristics. Interior access may be provided through removal of the globe top to thereby provide accessibility to the LED board mounted on the heat transfer plate.
摘要翻译：描述了传统的橡木式地球仪，其将LED的利用作为照明源。提供了支撑散热板，其延伸到橡木式灯具的外部周边，从而允许热量从LED直接传递到橡木式灯具的外部，同时保持橡木式地球结构的完整性。位于球体内部的每个LED上的多个可单独定向的透镜允许有效的筒灯和期望的光学特性。可以通过去除球形顶部提供内部通路，从而提供对安装在传热板上的LED板的可及性。

10. 发明申请

US20100061091A1 LED BASED ACORN STYLE LUMINAIRE 有权
标题翻译： LED基于ACORN风格灯
公开(公告)号：US20100061091A1
公开(公告)日：2010-03-11
申请号：US12205568
申请日：2008-09-05
申请人： Guy Galipeau , Michel Fortin , Jean-Francois Laporte , Jonathan Hardy
发明人： Guy Galipeau , Michel Fortin , Jean-Francois Laporte , Jonathan Hardy
IPC分类号： F21V29/00
CPC分类号： F21V29/70 , F21S8/088 , F21Y2115/10
摘要： A conventional acorn style globe is described incorporating the utilization of LED's as an illumination source. A supporting heat dissipation plate is provided which extends to the exterior periphery of the acorn style luminaire allowing heat to transfer from the LED's directly to the exterior of the acorn style luminaire while maintaining the integrity of an acorn style globe construction. A plurality of individually orientable lenses on each of the LED's positioned within the interior of the globe allow for efficient downlight and desirable optical characteristics. Interior access may be provided through removal of the globe top to thereby provide accessibility to the LED board mounted on the heat transfer plate.
摘要翻译：描述了传统的橡木式地球仪，其将LED的利用作为照明源。提供了支撑散热板，其延伸到橡木式灯具的外部周边，从而允许热量从LED直接传递到橡木式灯具的外部，同时保持橡木式地球结构的完整性。位于球体内部的每个LED上的多个可单独定向的透镜允许有效的筒灯和期望的光学特性。可以通过去除球形顶部提供内部通路，从而提供对安装在传热板上的LED板的可及性。

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