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    • 5. 发明授权
    • Penicillin antibiotics
    • 青霉素抗生素
    • US3936443A
    • 1976-02-03
    • US595105
    • 1975-07-11
    • Michael GregsonMartin Christopher CookGordon Ian Gregory
    • Michael GregsonMartin Christopher CookGordon Ian Gregory
    • C07D307/54C07D333/24C07D499/70
    • C07D307/54C07D333/24
    • The invention provides novel antibiotic compounds which are 6.beta.-acylamidopenam-3-carboxylic acids and non-toxic derivatives thereof, characterized in that the acylamido group has the structure ##EQU1## WHERE R is a hydrogen atom or an organic group and R.sup.a is a hydrogen atom or an acyl group. The compounds are syn isomers or exist as mixtures containing at least 75% of the syn isomer. These antibiotic compounds possess high antibacterial activity against a range of gram positive and gram negative organisms coupled with particularly high stability to .beta.-lactamases produced by various gram negative organisms. The invention is also concerned with the administration of the compounds.
    • 本发明提供了新颖的抗生素化合物,它们是6β-酰基氨基青蒿素-3-羧酸及其无毒的衍生物,其特征在于酰基酰胺基具有结构RCCONH PARALLEL N | ORA,其中R是氢原子或有机基团, Ra是氢原子或酰基。 这些化合物是顺式异构体,或作为含有至少75%的顺式异构体的混合物存在。 这些抗生素化合物对革兰氏阳性和革兰氏阴性生物体的一系列革兰氏阴性菌具有很高的抗菌活性,与各种革兰氏阴性生物产生的β-内酰胺酶具有特别高的稳定性。 本发明还涉及化合物的给药。
    • 8. 发明授权
    • Method and apparatus for analyzing a communications network link
    • 用于分析通信网络链路的方法和装置
    • US07072305B1
    • 2006-07-04
    • US09430687
    • 1999-10-29
    • J. Michael Gregson
    • J. Michael Gregson
    • H04J1/16H04J3/14
    • H04L1/24H04L41/0681H04L43/067H04L43/0829H04L43/0847H04L43/0852H04L43/106H04L43/16H04L43/50
    • A method and system for testing at least one link in a communications network. The system includes first and second analyzer units that are configured to test an existing link in the network. Alternatively, the first and second analyzer units may be configured to establish and test a link between them. A computer remotely controls the first and second analyzer units to perform testing of various communication parameters, such as packet loss and latency. Each analyzer unit may be configured to collect data over a predetermined duration to establish a network baseline of operation, which may be used to detect future network malfunctions. The computer estimates the deviation of communication parameters from the network baseline.
    • 一种用于测试通信网络中的至少一个链路的方法和系统。 该系统包括被配置为测试网络中的现有链路的第一和第二分析器单元。 或者,第一和第二分析器单元可以被配置为建立和测试它们之间的链接。 计算机远程控制第一和第二分析器单元来执行各种通信参数的测试,例如分组丢失和延迟。 每个分析器单元可以被配置为在预定的持续时间内收集数据以建立操作的网络基线,其可以用于检测未来的网络故障。 计算机估计通信参数与网络基线的偏差。