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1. 发明授权

US09848843B2 Dynamic perfusion imaging 有权
公开(公告)号：US09848843B2
公开(公告)日：2017-12-26
申请号：US14112047
申请日：2012-04-17
申请人： Michael Grass , Holger Schmitt
发明人： Michael Grass , Holger Schmitt
IPC分类号： A61B6/00
CPC分类号： A61B6/481 , A61B6/00 , A61B6/486 , A61B6/503 , A61B6/507 , A61B6/5217 , A61B6/542 , A61B6/545 , F04C2270/0421
摘要： A method includes scanning a region of interest, during a contrast agent based perfusion scan, at a predetermined temporal sampling rate during contrast agent uptake in the region of interest, and generating time frame data indicative of the scanned region of interest. The method further includes identifying a predetermined change in an amount of the contrast agent in the region of interest from the time frame data. The method further includes scanning the region of interest at a lower temporal sampling rate, which is lower than the temporal sampling rate during the contrast agent uptake, in response to identifying the predetermined change in the amount of the contrast agent in the region of interest.

2. 发明授权

US09597042B2 Perfusion imaging 有权
公开(公告)号：US09597042B2
公开(公告)日：2017-03-21
申请号：US13266556
申请日：2010-04-09
申请人： Roland Proksa , Michael Grass
发明人： Roland Proksa , Michael Grass
IPC分类号： G06K9/00 , A61B6/03 , A61B6/00
CPC分类号： A61B6/032 , A61B6/481 , A61B6/482 , A61B6/486 , A61B6/504 , A61B6/507
摘要： A method is disclosed that includes decomposing, with a decomposer, agent-based time series projection data for an object or a subject into at least an agent based component. A projection data decomposer includes a time series decomposer that determines agent-based projection data based on agent-based time series projection data based on at least two energy dependent components. A computer readable storage medium containing instructions which, when executed by a computer, cause the computer to perform the act of determining an agent-based component of agent-based time series projection data utilizing at least two components of the agent-based time series projection is provided.

3. 发明申请

US20160237244A1 PRODUCTION OF ESTER MIXTURES 审中-公开
标题翻译：生产混合物
公开(公告)号：US20160237244A1
公开(公告)日：2016-08-18
申请号：US15047051
申请日：2016-02-18
申请人： Florian Sebastian BOECK , Carsten GEHLEN , Michael GRASS , Benjamin WOLDT
发明人： Florian Sebastian BOECK , Carsten GEHLEN , Michael GRASS , Benjamin WOLDT
IPC分类号： C08K5/12 , C07C69/82 , C08K5/1539 , C07C69/753 , C07C69/704 , C08K5/11 , C07C67/02 , C07C67/08
CPC分类号： C08K5/12 , C07C67/03 , C07C67/08 , C08K2201/014 , C07C69/40 , C07C69/82 , C07C69/75 , C07C69/80 , C07C69/704 , C08L27/06
摘要： Ester mixtures comprising the esters A(COOR1)(COOR1)x, A(COOR1)(COOR2)x, A(COOR2)(COOR1)x and A(COOR2)(COOR2)x, can be produced in a targeted way by processes in which acids A(COOH)x+1 or derivatives thereof are reacted with an amount (m1+s1) of R1OH and an amount m2 of R2OH, the reaction mixture being heated at boiling, the alcohol R1OH having a lower boiling point than the alcohol R2OH, A being an aromatic, alicyclic or aliphatic radical, x being 1 or 2, and R1 and R2 independently of one another being substituted or unsubstituted aryl radicals or linear or branched, substituted or unsubstituted alkyl radicals having 3 to 20 carbon atoms, m1 and m2 corresponding to the mole equivalents of the alcohol radicals OR1 and OR2 to be introduced into A(COOH)x+1 or derivatives thereof, and s1 being greater than 0.
摘要翻译：可以以目标方式通过方法制备包含酯A（COOR1）（COOR1）x，A（COOR1）（COOR2）x，A（COOR2）（COOR1）x和A（COOR2）（COOR2）其中酸A（COOH）x + 1或其衍生物与R1OH的量（m1 + s1）和R2OH的量m2反应，将反应混合物在沸腾下加热，醇R1OH的沸点低于醇R2OH，A是芳族，脂环族或脂族基团，x是1或2，R1和R2彼此独立地是取代或未取代的芳基或具有3至20个碳原子的直链或支链，取代或未取代的烷基， m1和m2对应于待引入A（COOH）x + 1的醇基OR1和OR2的摩尔当量或其衍生物，s1大于0。

4. 发明申请

US20160237243A1 PENTYL NONYL TEREPHTHALATES 审中-公开
标题翻译：戊二酸非特异性
公开(公告)号：US20160237243A1
公开(公告)日：2016-08-18
申请号：US15046242
申请日：2016-02-17
申请人： Benjamin WOLDT , Florian Sebastian BOECK , Michael GRASS , Harald HAEGER
发明人： Benjamin WOLDT , Florian Sebastian BOECK , Michael GRASS , Harald HAEGER
IPC分类号： C08K5/12 , C08K5/101
摘要： Mixtures containing dipentyl terephthalate, dinonyl terephthalate and pentyl nonyl terephthalate can be prepared with a predetermined distribution of the individual esters in the mixture, and used as plasticizers.
摘要翻译：含有对苯二甲酸二戊酯，对苯二甲酸二壬酯和对苯二甲酸戊酯的混合物可以以混合物中各个酯的预定分布来制备，并用作增塑剂。

5. 发明申请

US20160060426A1 MIXTURES OF EPOXIDIZED FATTY ACID ESTERS 审中-公开
标题翻译：环氧化脂肪酸酯的混合物
公开(公告)号：US20160060426A1
公开(公告)日：2016-03-03
申请号：US14836092
申请日：2015-08-26
申请人： Benjamin WOLDT , Florian BOECK , Andreas GEVERS , Michael GRASS
发明人： Benjamin WOLDT , Florian BOECK , Andreas GEVERS , Michael GRASS
IPC分类号： C08K5/1515 , C08K5/09 , C07D301/02
CPC分类号： C08K5/1515 , C07D301/02 , C08K5/09 , C11C3/00
摘要： A mixture (1) can be prepared in a controlled manner and used as a plasticizer, the mixture contains an epoxidized fatty acid ester A; and a compound B containing a fatty acid chain and having no functional group including a multiple bond in the fatty acid chain. The proportion by mass of compound B is smaller in said mixture (1) than a proportion of compound B in a mixture (2) of compounds containing a fatty acid chain from which the mixture (1) comprising epoxidized fatty acid ester A has been prepared.
摘要翻译：混合物（1）可以以受控的方式制备并用作增塑剂，该混合物含有环氧化脂肪酸酯A; 和含有脂肪酸链的化合物B，在脂肪酸链中不含有多重键的官能团。化合物B的质量比例比制备包含环氧化脂肪酸酯A的混合物（1）的含有脂肪酸链的化合物的混合物（2）中化合物B的比例小。

6. 发明申请

US20160009898A1 ISONONYL ESTERS BASED ON FATTY ACIDS OR FATTY ACID MIXTURES FROM TALL OIL OR LINSEED OIL 审中-公开
标题翻译：基于脂肪酸或脂肪酸混合物的来自石油或林油的异烟肼
公开(公告)号：US20160009898A1
公开(公告)日：2016-01-14
申请号：US14773649
申请日：2014-02-14
申请人： Benjamin Woldt , Michael Grass , Andreas Gevers
发明人： Benjamin Woldt , Michael Grass , Andreas Gevers
IPC分类号： C08K5/1515 , C07D303/16 , C07D407/06
CPC分类号： C08K5/1515 , C07D303/16 , C07D407/06 , C08K5/101 , C08L27/06
摘要： The invention relates to an isononyl ester or isononyl ester mixture of an epoxidized fatty acid or an epoxidized fatty acid mixture, the fatty acid or fatty acid mixture being extracted from tall oil or linseed oil and the average number of epoxide groups per fatty acid being greater than 1.00.
摘要翻译：本发明涉及环氧化脂肪酸或环氧化脂肪酸混合物的异壬酯或异壬基酯混合物，脂肪酸或脂肪酸混合物由妥尔油或亚麻子油提取，每个脂肪酸的平均环氧基数大于超过1.00。

7. 发明授权

US09087404B2 Reconstruction for cone-beam computed tomography imaging with off-center flat panel detector 有权
标题翻译：用偏心平板检测器进行锥束计算机断层扫描成像的重建
公开(公告)号：US09087404B2
公开(公告)日：2015-07-21
申请号：US13697445
申请日：2011-04-25
申请人： Eberhard S. Hansis , Dirk Schaefer , Michael Grass
发明人： Eberhard S. Hansis , Dirk Schaefer , Michael Grass
IPC分类号： G01N23/04 , G06T1/00 , G06T11/00
CPC分类号： G06T11/008 , G06T11/006 , G06T2211/432
摘要： Computed tomography (CT) reconstruction includes reconstructing an axially extended reconstructed image from a measured cone beam x-ray projection data set (Pm), optionally having an off-center geometry. The reconstructing is performed for an extended volume (eFOV) comprising a reconstructable volume (rFOV) of the measured cone beam x ray data set that is extended along the axial direction. The projection data set may be weighted in the volume domain. Iterative reconstruction may be used, including initializing a constant volume and performing one or more iterations employing a first iterative update followed by one or more iterations employing a second, different iterative update. Alternatively, backprojection filtration (BPF) reconstruction may be used, including transforming the projection data set to a new geometry including finite differences between neighboring projection views and performing BPF using Hilbert filtering along a plurality of different directions and averaging the resultant reconstructed images to generate the final reconstructed image.
摘要翻译：计算机断层摄影（CT）重建包括从测量的锥形束X射线投影数据集（Pm）重建轴向延伸的重建图像，可选地具有偏心几何。对包括沿轴向延伸的测量的锥形束x射线数据集的可重建体积（rFOV）的扩展体积（eFOV）进行重建。投影数据集可以在体积域中加权。可以使用迭代重建，包括初始化恒定体积并且使用第一迭代更新执行一个或多个迭代，随后使用第二，不同迭代更新的一个或多个迭代。或者，可以使用反投影过滤（BPF）重建，包括将投影数据集变换为包括相邻投影视图之间的有限差异的新几何，并且使用沿着多个不同方向的希尔伯特滤波来执行BPF，并平均所得到的重建图像以产生最终重建图像。

8. 发明授权

US09002089B2 Image data registration for dynamic perfusion CT 有权
标题翻译：用于动态灌注CT的图像数据注册
公开(公告)号：US09002089B2
公开(公告)日：2015-04-07
申请号：US13643167
申请日：2011-04-12
申请人： Michael Grass , Alfonso Agatino Isola
发明人： Michael Grass , Alfonso Agatino Isola
IPC分类号： G06K9/00 , G06T7/00 , A61B6/00
CPC分类号： G06T7/0026 , A61B6/507 , G06T7/32 , G06T2207/10076 , G06T2207/30104
摘要： A method of registering a 4D contrast enhanced image data set, wherein the 4D contrast enhanced image data set includes image data of the same volume of interest acquired at different timeframes with changing contrast enhancement, the volume of interest includes moving structure, and the different timeframes correspond to a predetermined motion phase of interest in different motion cycles of the moving structure, the method, comprising: registering image data corresponding to a plurality of the different timeframes with reference image from one of the timeframes.
摘要翻译：一种注册4D对比度增强图像数据集的方法，其中所述4D对比度增强图像数据集包括在改变对比度增强的不同时间帧处获取的相同感兴趣体积的图像数据，所述感兴趣的体积包括移动结构和不同的时间帧对应于移动结构的不同运动周期中的感兴趣的预定运动相位，该方法包括：将与多个不同时间帧对应的图像数据与来自其中一个时间帧的参考图像进行对应。

9. 发明申请

US20150018576A1 METHOD AND DEVICE FOR THE HYDROFORMYLATION OF ISOBUTENE AND FOR THE SEPARATION OF THE PRODUCT MIXTURE 有权
标题翻译：用于分离产品混合物的方法和装置
公开(公告)号：US20150018576A1
公开(公告)日：2015-01-15
申请号：US14380647
申请日：2013-02-11
申请人： Goetz Baumgarten , Michael Grass , Alfred Kaizik , Markus Winterberg , Hans-Gerd Lueken , Bart Hamers , Markus Priske , Dirk Fridag , Robert Franke , Dieter Hess
发明人： Goetz Baumgarten , Michael Grass , Alfred Kaizik , Markus Winterberg , Hans-Gerd Lueken , Bart Hamers , Markus Priske , Dirk Fridag , Robert Franke , Dieter Hess
IPC分类号： C07C51/43 , C07C51/235 , C07C45/78 , C07C45/50
CPC分类号： C07C51/43 , B01D61/027 , C07C45/50 , C07C45/505 , C07C45/786 , C07C45/82 , C07C51/235 , C07C47/02
摘要： The invention relates to a method for producing a product mixture (2) by means of the technical hydroformylation of a hydrocarbon stream (1) that contains isobutene, and for separating the product mixture (2) that is obtained, as well as to a device for the claimed method and to the use of a claimed device. The problem addressed thereby is that of providing a method and an associated device that allow the amount of high-boiling substances in the product mixture (2) to be kept as low as possible and thus the yield of the reaction to be increased. The problem is solved by the use of a nano-filtration device (M) for separating the catalyst from the product mixture (2), said device having especially high permeability to 3-methylbutanoic acid.
摘要翻译：本发明涉及一种通过含有异丁烯的烃流（1）的技术加氢甲酰化以及用于分离获得的产物混合物（2）以及制备产物混合物（2）的方法，用于所要求保护的方法和所要求保护的装置的使用。由此提出的问题是提供一种方法和相关联的装置，其允许将产物混合物（2）中的高沸点物质的量保持尽可能低，从而提高反应的产率。通过使用纳米过滤装置（M）从产物混合物（2）中分离催化剂来解决该问题，所述装置对3-甲基丁酸具有特别高的渗透性。

10. 发明申请

US20140088226A1 DIANHYDROHEXITOL DIESTERS OF 2-ETHYLHEPTANOIC ACID 审中-公开
标题翻译：二乙二醇酸的二氢呋喃糖醇
公开(公告)号：US20140088226A1
公开(公告)日：2014-03-27
申请号：US14119994
申请日：2012-04-26
申请人： Andreas Gevers , Hinnerk Becker , Michael Grass , Markus Winterberg , Dietrich Maschmeyer , Christian Boeing
发明人： Andreas Gevers , Hinnerk Becker , Michael Grass , Markus Winterberg , Dietrich Maschmeyer , Christian Boeing
IPC分类号： C08K5/1535
CPC分类号： C08K5/1535 , C07D493/04 , C08K5/0016 , C08L27/06
摘要： Dianhydrohexitol diesters of 2-ethylheptanoic acid
摘要翻译： 2-乙基庚酸的二氢己糖二酯

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