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    • 2. 发明授权
    • Method of inhibiting sweetness
    • 抑制甜味的方法
    • US4567053A
    • 1986-01-28
    • US599260
    • 1984-04-11
    • Michael G. Lindley
    • Michael G. Lindley
    • A21D2/14A23G3/00A23G3/36A23L1/09A23L1/226A23L1/236A23L3/3463A23L3/42A61K47/12A61K47/22A23L1/22C07C53/132A61K9/20A61K31/70
    • A23G3/36A21D2/14A23L27/204A23L27/39A23L29/30A23L3/3463A23L3/42
    • The sweetness of an ingestible product containing a sweetening sugar or sugar alcohol in large quantities can be reduced by incorporating therein a sweetness-reducing amount of at least one compound of the general formula: ##STR1## in which m represents 0 or 1, and when m represents 0, n represents 1, 2 or 3, and p represents 1, 2, 3 or 4, and when m represents 1, n represents 1 or 2 and p represents 0, 1, 2, 3 or 4; the substituents R, which may be the same or different, each represent a lower alkoxy group, e.g. with 1 to 5 carbon atoms, phenoxy group or a lower alkyl or trifluoromethyl group; and/or two substituents R together represent an aliphatic chain linked to the phenyl ring at two positions, either directly or via an oxa-group, e.g. an alkylenedioxy, alkenylenedioxy, alkylenoxy or alkenylenoxy group; and/or one substituent R represents a hydroxy group while at least one other substituent R represents an alkoxy group; and X.sup.+ represents a physiologically acceptable cation.
    • 通过在其中加入甜味减少量的至少一种下列通式的化合物可以降低含有大量甜味剂糖或糖醇的可摄取产品的甜度:其中m表示0或1 ,当m表示0时,n表示1,2或3,p表示1,2,3或4,当m表示1时,n表示1或2,p表示0,1,2,3或4。 取代基R可以相同或不同,各自表示低级烷氧基,例如低级烷氧基。 具有1至5个碳原子,苯氧基或低级烷基或三氟甲基; 和/或两个取代基R一起表示在两个位置连接到苯环的脂族链,直接或经由氧杂基团,例如, 亚烷基二氧基,亚烯基二氧基,亚烷基氧基或亚烯基氧基; 和/或一个取代基R表示羟基,而至少一个其它取代基R表示烷氧基; X +表示生理上可接受的阳离子。
    • 5. 发明授权
    • Method of modifying sweet taste
    • 改善甜味的方法
    • US5045336A
    • 1991-09-03
    • US865926
    • 1986-05-14
    • Michael G. LindleyElner B. Rathbone
    • Michael G. LindleyElner B. Rathbone
    • A23L1/22A21D2/14A21D13/00A21D13/08A23C15/12A23G3/34A23G4/00A23G9/32A23G9/44A23G9/52A23L1/00A23L1/06A23L1/226A23L1/236A23L1/30A23L1/40C07C59/68C07C59/70C07C59/90C07C59/92C12G3/06
    • A21D13/0016A21D2/145A23G3/346A23L27/39C07C59/68C07C59/70C07C59/90C07C59/92C12G3/06A23G2200/00
    • The sweetness of an ingestible product or oral composition containing a sweetening sugar or sugar alcohol in relatively large quantities can be reduced and thereby the flavor enhanced by incorporation of at least one compound of the general formula (I) ##STR1## in which m represents 0.1; A represents a homocyclic or heterocyclic aromatic group with one or more rings; and B represents a hydrogen atom, a lower aliphatic group with 1-3 carbon atoms or a phenyl group; or, when m represents O, A and B together represent a bivalent homocyclic or heterocyclic aromatic group with two or more rings, or a methylidene group carrying as a substituent a homocyclic or heterocyclic aromatic group with one or more rings; an aromatic ring of A, or of A and B together, optionally carrying one to three substituents selected from lower alkoxy groups, lower alkyl or alkenyl groups, formyl or acetyl groups, hydroxy groups or acyloxy groups, and halogen atoms;C represents a hydrogen atom or an alkyl group or, when m represents O, a hydroxy or alkoxy group;D represents a oxygen or sulphur atom;X.sup.+ represents a hydrogen ion or another physiologically compatible cation;with the proviso that m represents 1 when S represents a substituted or unsubstituted phenyl group and B and C both represent hydrogen atoms; or when A represents an unsubstituted phenyl group, B represents an alkyl group and C represents a hydrogen atom.
    • 可以减少含有相对较大量的甜味糖或糖醇的可摄取产品或口服组合物的甜度,从而通过加入至少一种通式(I)的化合物(I)来增强风味,其中 m表示0.1; A表示具有一个或多个环的双环或杂环芳族基团; B表示氢原子,具有1-3个碳原子的低级脂族基或苯基; 或者当m表示O时,A和B一起表示具有两个或更多个环的二价稠环或杂环芳族基团,或带有一个或多个环的带有杂环或杂环芳族基团的取代基的亚甲基; A或A或A的芳环在一起,任选地带有1-3个选自低级烷氧基,低级烷基或烯基,甲酰基或乙酰基,羟基或酰氧基和卤素原子的取代基; C表示氢原子或烷基,或者当m表示O时,羟基或烷氧基; D表示氧或硫原子; X +表示氢离子或另一生理上相容的阳离子; 条件是当S表示取代或未取代的苯基时,m表示1,B和C均表示氢原子; 或当A表示未取代的苯基时,B表示烷基,C表示氢原子。