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1. 发明专利

IL292704A Methods of treatment with antibodies against bcma and cd3 未知
公开(公告)号：IL292704A
公开(公告)日：2022-07-01
申请号：IL29270422
申请日：2022-05-02
申请人： SQUIBB BRISTOL MYERS CO , MICHAEL BURGESS , KRISTEN HEGE , KAUSHIK DATTA , ISAAC BOSS , MINH DIEM VU
发明人： MICHAEL BURGESS , KRISTEN HEGE , KAUSHIK DATTA , ISAAC BOSS , MINH DIEM VU
IPC分类号： A61K39/00 , A61P35/00 , A61P35/02 , C07K16/28
摘要： The present invention relates to methods of treating a patient having a disorder associated with BCMA expression (e.g. BCMA-expressing B-cell cancers, such as multiple myeloma) using dose-escalation dosing regimens with multispecific (e.g. bispecific) antibodies that bind to CD3 and BCMA.

2. 发明授权

US08606345B2 Medical dual lens camera for documentation of dermatological conditions with laser distance measuring 有权
标题翻译：医用双镜头相机用于记录激光距离测量的皮肤病学条件
公开(公告)号：US08606345B2
公开(公告)日：2013-12-10
申请号：US12872357
申请日：2010-08-31
申请人： John David Taylor , Gregory Allen Yotz , Michael Dave Shaw , Robert Samuel Burkhalter , James Michael Burgess , Richard Kent Richardson
发明人： John David Taylor , Gregory Allen Yotz , Michael Dave Shaw , Robert Samuel Burkhalter , James Michael Burgess , Richard Kent Richardson
IPC分类号： A61B5/05
CPC分类号： A61B5/0059 , A61B5/445 , A61B5/446
摘要： An imaging apparatus in accordance with the present invention comprises a hand-held, battery powered imaging device that provides: (1) an Identification Picture wherein an image of the patient's face is captured for identification purposes; (2) an Area of Interest picture wherein an image of the general area of interest on the patient is captured; and (3) a Subject of Interest picture wherein an image of the subject lesion of interest is captured. Two digital imaging systems, including a wide-angle (e.g. fisheye) imaging system and a macro (close-up) imaging system, are provided to allow for the simultaneous capture of AOI and SOI images thereby capturing an image that identifies the location of the lesion on the body and an image that comprises a close-up view of the lesion. A light source or flash provides illumination during the image capture phase. A laser range finding configuration including spaced first and second lasers are angularly disposed so as to cast beams that intersect at a desired distance from the imaging apparatus thereby allowing the user to quickly position the imaging apparatus at a predetermined distance from the patient when capturing images. Audible output provides the user with input to assist in properly capturing the images, and a trigger-type actuator is provided to initiate image capture.
摘要翻译：根据本发明的成像装置包括手持式电池供电的成像装置，其提供：（1）识别图像，其中捕获患者脸部的图像用于识别目的; （2）感兴趣区域图像，其中捕获患者的一般感兴趣区域的图像; 和（3）感兴趣的主题图片，其中捕获感兴趣的受试者损伤的图像。提供两个数字成像系统，包括广角（例如鱼眼）成像系统和宏（特写）成像系统，以允许同时捕获AOI和SOI图像，从而捕获识别位置的图像身体上的病变和包括病变的特写视图的图像。光源或闪光灯在图像捕获阶段提供照明。包括间隔开的第一和第二激光器的激光测距配置被成角度地设置成铸造与成像设备相距一定距离的光束，从而允许用户在拍摄图像时将成像设备快速地定位在离病人预定距离处。声音输出为用户提供了有助于正确捕获图像的输入，并提供触发式执行器来启动图像捕获。

3. 发明授权

US08567836B2 Gripping assembly and gripping members for a grapple attachment 有权
标题翻译：用于抓钩附件的夹紧组件和夹紧构件
公开(公告)号：US08567836B2
公开(公告)日：2013-10-29
申请号：US12794877
申请日：2010-06-07
申请人： Jason LaValley , Roger LaValley , Marvin Larson , Lawrence D. Kilpo , Michael Burgess
发明人： Jason LaValley , Roger LaValley , Marvin Larson , Lawrence D. Kilpo , Michael Burgess
IPC分类号： B66C1/42 , E21B19/20
CPC分类号： E21B19/155 , E21B19/14
摘要： A gripping assembly with gripping members, as part of a grapple attachment, used to grasp and manipulate elongated objects, for example pipe, is described. Due to the gripping action of the gripping members and tilt control capabilities of the grapple attachment, total positive control of the pipe is maintained, even if the gripping assembly picks up pipe off center. The gripping members are used at least in pairs and are mounted on a common main beam structure so that they are separated from each other. The gripping members are interchangeable with other gripping members to permit the grapple attachment to grasp different sized objects, thereby providing modularity to the grapple attachment. In one embodiment, the gripping members include a support member having a main beam structure opening extending laterally therethrough that is configured to receive a main beam structure of the gripping assembly.
摘要翻译：描述了作为用于抓握和操纵细长物体（例如管道）的作为抓斗附件的一部分的夹持构件的夹持组件。由于抓握构件的夹持动作和抓斗附件的倾斜控制能力，即使夹紧组件从中心取出管，也能保持管子的全面正面控制。夹持构件至少成对使用并且被安装在共同的主梁结构上，使得它们彼此分离。夹持构件可与其他夹持构件互换，以允许抓钩附接抓住不同尺寸的物体，从而为抓斗附件提供模块化。在一个实施例中，夹持构件包括支撑构件，该支撑构件具有横向穿过其延伸的主梁结构开口，该主梁结构开口构造成容纳夹紧组件的主梁结构。

4. 发明申请

US20120109363A1 METHOD & SYSTEM FOR PERFORMING A PACKAGE PRE-LOAD OPERATION IN ACCORDANCE WITH A DISPATCH PLAN 有权
标题翻译：根据分配计划执行包装预加载操作的方法和系统
公开(公告)号：US20120109363A1
公开(公告)日：2012-05-03
申请号：US13305519
申请日：2011-11-28
申请人： JUAN R. PEREZ , DUANE ANDERSON , DAVID POTTEIGER , MICHAEL BURGESS
发明人： JUAN R. PEREZ , DUANE ANDERSON , DAVID POTTEIGER , MICHAEL BURGESS
IPC分类号： G06F7/00
CPC分类号： G06Q50/28 , B07C3/14 , B07C3/18 , G06Q10/08 , G06Q10/087 , H03M7/40
摘要： The present invention provides systems and methods for electronically-capturing a destination address of a package and for using the destination address to automate a package pre-load operation. An embodiment of the invention includes a compression system for compressing the destination address as a compressed MaxiCode symbol, a smart shipping label system for generating a shipping label with a compressed MaxiCode and a pre-load assist system for generating package handling instructions from the electronically-captured destination address.
摘要翻译：本发明提供用于电子捕获包裹的目的地地址并使用目的地地址来自动化包装预加载操作的系统和方法。本发明的实施例包括用于将目的地地址压缩为压缩MaxiCode符号的压缩系统，用于生成具有压缩MaxiCode的运输标签的智能运输标签系统和用于从电子方式生成包装处理指令的预加载辅助系统，捕获的目的地址。

5. 发明申请

US20110054310A1 PORTABLE MEDICAL IMAGING APPARATUS FOR DOCUMENTATION OF DERMATOLOGICAL AREAS AND SUBJECTS OF INTEREST 有权
标题翻译：便携式医疗成像装置用于文献区域和利益主体
公开(公告)号：US20110054310A1
公开(公告)日：2011-03-03
申请号：US12872357
申请日：2010-08-31
申请人： John David Taylor , Gregory Allen Yotz , Michael Dave Shaw , Robert Samuel Burkhalter , James Michael Burgess , Richard Kent Richardson
发明人： John David Taylor , Gregory Allen Yotz , Michael Dave Shaw , Robert Samuel Burkhalter , James Michael Burgess , Richard Kent Richardson
IPC分类号： A61B6/00
CPC分类号： A61B5/0059 , A61B5/445 , A61B5/446
摘要： An imaging apparatus in accordance with the present invention comprises a hand-held, battery powered imaging device that provides: (1) an Identification Picture wherein an image of the patient's face is captured for identification purposes; (2) an Area of Interest picture wherein an image of the general area of interest on the patient is captured; and (3) a Subject of Interest picture wherein an image of the subject lesion of interest is captured. Two digital imaging systems, including a wide-angle (e.g. fisheye) imaging system and a macro (close-up) imaging system, are provided to allow for the simultaneous capture of AOI and SOI images thereby capturing an image that identifies the location of the lesion on the body and an image that comprises a close-up view of the lesion. A light source or flash provides illumination during the image capture phase. A laser range finding configuration including spaced first and second lasers are angularly disposed so as to cast beams that intersect at a desired distance from the imaging apparatus thereby allowing the user to quickly position the imaging apparatus at a predetermined distance from the patient when capturing images. Audible output provides the user with input to assist in properly capturing the images, and a trigger-type actuator is provided to initiate image capture.
摘要翻译：根据本发明的成像装置包括手持式电池供电的成像装置，其提供：（1）识别图像，其中捕获患者脸部的图像用于识别目的; （2）感兴趣区域图像，其中捕获患者的一般感兴趣区域的图像; 和（3）感兴趣的主题图片，其中捕获感兴趣的受试者损伤的图像。提供两个数字成像系统，包括广角（例如鱼眼）成像系统和宏（特写）成像系统，以允许同时捕获AOI和SOI图像，从而捕获识别位置的图像身体上的病变和包括病变的特写视图的图像。光源或闪光灯在图像捕获阶段提供照明。包括间隔开的第一和第二激光器的激光测距配置被成角度地设置成铸造与成像设备相距一定距离的光束，从而允许用户在拍摄图像时将成像设备快速地定位在离病人预定距离处。声音输出为用户提供了有助于正确捕获图像的输入，并提供触发式执行器来启动图像捕获。

6. 发明申请

US20100047040A1 DEPLOYMENT SYSTEM 审中-公开
标题翻译：部署制度
公开(公告)号：US20100047040A1
公开(公告)日：2010-02-25
申请号：US12301721
申请日：2007-05-21
申请人： Trevor Michael Burgess , Mauro Zaccaria
发明人： Trevor Michael Burgess , Mauro Zaccaria
IPC分类号： B63B27/00 , B63B35/00 , B65G67/60
CPC分类号： B63B35/003 , B63B27/02 , B63B27/30 , B63B27/36 , B63B2027/165
摘要： A deployment system (12) for deploying equipment from a vessel (10), such as sea going vessel, comprises a support structure (18) adapted to be mounted on the deck (14) of a vessel (10) and a cradle (20) mounted on the support structure (18) and adapted to be support equipment (16) to be deployed, wherein the cradle (20) is configurable between storage configuration and a deployment configuration. A carriage (22) is mounted on the cradle (20) and is adapted to engage equipment (16) to be deployed, wherein the carriage (22) is translatable relative to the cradle (20) to move equipment (16) between stored and deployed positions. In one disclosed embodiment, the deployment system (12) is arrangement for use in deploying an elongate structure, such as a subsea well intervention system, for a sea going vessel (10).
摘要翻译：用于从诸如海上船只的船舶（10）部署设备的部署系统（12）包括适于安装在容器（10）和托架（20）的甲板（14）上的支撑结构（18））安装在所述支撑结构（18）上并且适于被配置的支撑设备（16），其中所述支架（20）可在存储配置和部署配置之间配置。托架（22）安装在托架（20）上并且适于接合待部署的设备（16），其中托架（22）可相对于托架（20）平移，以将设备（16）移动到存储和部署职位。在一个公开的实施例中，展开系统（12）是用于展开用于海上运输船（10）的细长结构（例如海底井介入系统）的布置。

7. 发明申请

US20100029676A1 T315A AND F317I MUTATIONS OF BCR-ABL KINASE DOMAIN 审中-公开
标题翻译： T315A和F317I BCR-ABL激酶域的突变
公开(公告)号：US20100029676A1
公开(公告)日：2010-02-04
申请号：US12092360
申请日：2006-11-03
申请人： Charles L. Sawyers , Michael Burgess , Neil Pravin Shah , Francis Y. Lee , John S. Tokarski , Herbert E. Klei
发明人： Charles L. Sawyers , Michael Burgess , Neil Pravin Shah , Francis Y. Lee , John S. Tokarski , Herbert E. Klei
IPC分类号： A61K31/497 , C12Q1/48 , G01N33/53 , C12Q1/68
CPC分类号： C12Q1/6886 , C12Q2600/106 , C12Q2600/136
摘要： The present invention relates to mutant BCR-ABL kinase proteins, and to diagnostic and therapeutic methods and compositions useful in the management of disorders, for example cancers, involving cells that express such mutant BCR-ABL kinase proteins.
摘要翻译：本发明涉及突变型BCR-ABL激酶蛋白，以及可用于治疗病症（例如涉及表达这种突变型BCR-ABL激酶蛋白的细胞）的癌症的诊断和治疗方法和组合物。

8. 发明申请

US20090216214A1 Therapeutic agent treat to target system 审中-公开
标题翻译：治疗剂治疗目标系统
公开(公告)号：US20090216214A1
公开(公告)日：2009-08-27
申请号：US12001252
申请日：2007-12-12
申请人： Burton H. Sage , Bruce Michael Burgess , Michael Albert Klimowicz
发明人： Burton H. Sage , Bruce Michael Burgess , Michael Albert Klimowicz
IPC分类号： A61M5/31 , A61M37/00
CPC分类号： A61K9/0019 , A61M5/1782 , G06F19/326 , G06F19/3468 , G16H50/20
摘要： A method of calculating doses of insulin for a person with diabetes and administering the calculated doses to the person with diabetes is presented. Blood glucose values are provided to an insulin dosing calculator which implements a Treat to Target protocol to calculate appropriate doses of insulin. An insulin dispenser is also provided to fill an insulin administration device with the calculated dose.
摘要翻译：提出了一种计算糖尿病患者胰岛素剂量并向糖尿病患者给予计算剂量的方法。将血糖值提供给胰岛素给药计算器，该胰岛素给药计算机实施了对待靶向方案以计算适当剂量的胰岛素。还提供胰岛素分配器以用计算出的剂量填充胰岛素给药装置。

9. 发明申请

US20090187272A1 METHOD & SYSTEM FOR PERFORMING A PACKAGE PRE-LOAD OPERATION IN ACCORDANCE WITH A DISPATCH PLAN 有权
标题翻译：根据分配计划执行包装预加载操作的方法和系统
公开(公告)号：US20090187272A1
公开(公告)日：2009-07-23
申请号：US12180976
申请日：2008-07-28
申请人： Juan R. Perez , Duane Anderson , David Potteiger , Michael Burgess
发明人： Juan R. Perez , Duane Anderson , David Potteiger , Michael Burgess
IPC分类号： G06F7/00
CPC分类号： G06Q50/28 , B07C3/14 , B07C3/18 , G06Q10/08 , G06Q10/087 , H03M7/40
摘要： The present invention provides systems and methods for electronically-capturing a destination address of a package and for using the destination address to automate a package pre-load operation. An embodiment of the invention includes a compression system for compressing the destination address as a compressed MaxiCode symbol, a smart shipping label system for generating a shipping label with a compressed MaxiCode and a pre-load assist system for generating package handling instructions from the electronically-captured destination address.
摘要翻译：本发明提供用于电子捕获包裹的目的地地址并使用目的地地址来自动化包装预加载操作的系统和方法。本发明的实施例包括用于将目的地地址压缩为压缩MaxiCode符号的压缩系统，用于生成具有压缩MaxiCode的运输标签的智能运输标签系统和用于从电子方式生成包装处理指令的预加载辅助系统，捕获的目的地址。

10. 发明申请

US20090174705A1 Parallax scanning through scene object position manipulation 审中-公开
标题翻译：视差扫描通过场景对象位置操纵
公开(公告)号：US20090174705A1
公开(公告)日：2009-07-09
申请号：US12313820
申请日：2008-11-25
申请人： Michael Burgess Martin
发明人： Michael Burgess Martin
IPC分类号： G06T15/00
CPC分类号： H04N13/128 , H04N13/111 , H04N13/122 , H04N13/221 , H04N13/246 , H04N13/275
摘要： One aspect of the invention includes a method of generating virtual autostereoscopic images using a computer. The method may include defining at least one object in a virtual three-dimensional space and defining a virtual point of view. Images may be generated by simulating a parallax scanning motion of the at least one object. The generated images can be displayed and stored.
摘要翻译：本发明的一个方面包括使用计算机产生虚拟自动立体图像的方法。该方法可以包括在虚拟三维空间中定义至少一个对象并且定义虚拟视点。可以通过模拟至少一个对象的视差扫描运动来生成图像。可以显示和存储生成的图像。

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