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1. 发明公开

US20230257371A1 CYCLIC CYANOENONE DERIVATIVES AS MODULATORS OF KEAP1 审中-公开
公开(公告)号：US20230257371A1
公开(公告)日：2023-08-17
申请号：US18015671
申请日：2021-07-15
申请人： Michael ALTMAN , David A. CANDITO , Alec H. CHRISTIAN , Ornella DI PIETRO , Min LU , Umar Faruk MANSOOR , Katrina Marie MENNIE , Andrew J. MUSACCHIO , Anandan PALANI , Michael H. REUTERSHAN , David Matthew SHAW , MERCK SHARP & DOHME LLC , MSD R&D INNOVATION CENTRE LIMITED
发明人： Michael D. Altman , David A. Canditio , Alec H. Christian , Ornella Di Pietro , Min Lu , Umar Faruk Mansoor , Katrina Marie Mennie , Andrew J. Musacchio , Anandan Palani , Michael H. Reutershan , David Matthew Shaw , Ping Lui , Stephen St-Gallay
IPC分类号： C07D413/04 , C07D403/06 , C07D265/36 , C07D401/06 , C07D491/048 , C07D471/04 , C07D209/96 , C07D487/04 , C07D307/94
CPC分类号： C07D413/04 , C07D403/06 , C07D265/36 , C07D401/06 , C07D491/048 , C07D471/04 , C07D209/96 , C07D487/04 , C07D307/94
摘要： The present invention relates to cyclic cyanoenone derivatives of Formula (I) or pharmaceutically acceptable salts or solvates thereof, wherein R1, R2, R3, R4 and m are as defined herein. The present invention also relates to pharmaceutical compositions comprising the cyclic cyanoenone derivatives of Formula (I) and to their use in therapy.

2. 发明申请

US20130154236A1 Drawbar Pin Retention Device 有权
标题翻译：拉杆销保持装置
公开(公告)号：US20130154236A1
公开(公告)日：2013-06-20
申请号：US13331007
申请日：2011-12-20
申请人： Matthew Shaw , Alan Gustafson
发明人： Matthew Shaw , Alan Gustafson
IPC分类号： B60D1/28
CPC分类号： B60D1/02 , B60D1/28 , B60D1/60
摘要： In an example embodiment, an automatic engaging drawbar pin retention device includes a biased locking plate configured to retain a drawbar pin within a drawbar bore. The locking plate may be movably coupled to a drawbar clevis between a pin-lock to at least partly cover the bore and prevent removal of the drawbar pin and a pin-unlock condition.
摘要翻译：在示例性实施例中，自动接合拉杆销保持装置包括被配置为将牵引杆销保持在牵引杆孔内的偏置锁定板。锁定板可以可移动地联接到销闩之间的拉杆U形夹，以至少部分地覆盖孔，并且防止牵引杆销的移除和销的解锁状态。

3. 发明授权

US08210560B2 Drawbar bore adapter 有权
标题翻译：拉杆孔适配器
公开(公告)号：US08210560B2
公开(公告)日：2012-07-03
申请号：US12552751
申请日：2009-09-02
申请人： Matthew Shaw
发明人： Matthew Shaw
IPC分类号： B60D1/02
CPC分类号： B60D1/02 , B60D2001/008
摘要： In an example embodiment a drawbar pin bore adapter includes a bushing sized to fit within a drawbar pin bore of a first size and a retainer to secure the bushing to the drawbar. The bushing may include a primary portion having an outer diameter configured for insertion into the drawbar pin bore, an inner diameter configured to receive a drawbar pin of a second diameter; and an extension portion configured to protrude from the drawbar bore and engage the retainer to secure at least a portion of the bushing within the drawbar pin bore.
摘要翻译：在一个示例性实施例中，牵引杆销孔适配器包括尺寸适于装配在第一尺寸的牵引杆销孔和保持器中的衬套以将衬套固定到牵引杆。衬套可以包括具有构造成用于插入到拉杆销孔中的外径的主要部分，构造成容纳第二直径的拉杆销的内径; 以及延伸部分，其构造成从所述牵引杆孔突出并接合所述保持器，以将所述衬套的至少一部分固定在所述牵引杆销孔内。

4. 发明申请

US20110049840A1 Drawbar Bore Adapter 有权
标题翻译：拉杆孔适配器
公开(公告)号：US20110049840A1
公开(公告)日：2011-03-03
申请号：US12552751
申请日：2009-09-02
申请人： Matthew Shaw
发明人： Matthew Shaw
IPC分类号： B60D1/14
CPC分类号： B60D1/02 , B60D2001/008
摘要： In an example embodiment a drawbar pin bore adapter includes a bushing sized to fit within a drawbar pin bore of a first size and a retainer to secure the bushing to the drawbar. The bushing may include a primary portion having an outer diameter configured for insertion into the drawbar pin bore, an inner diameter configured to receive a drawbar pin of a second diameter; and an extension portion configured to protrude from the drawbar bore and engage the retainer to secure at least a portion of the bushing within the drawbar pin bore.
摘要翻译：在一个示例性实施例中，牵引杆销孔适配器包括尺寸适于装配在第一尺寸的牵引杆销孔和保持器中的衬套以将衬套固定到牵引杆。衬套可以包括具有构造成用于插入到拉杆销孔中的外径的主要部分，构造成容纳第二直径的拉杆销的内径; 以及延伸部分，其构造成从所述牵引杆孔突出并接合所述保持器，以将所述衬套的至少一部分固定在所述牵引杆销孔内。

5. 发明授权

US08632091B2 Drawbar pin retention device 有权
标题翻译：拉杆销保持装置
公开(公告)号：US08632091B2
公开(公告)日：2014-01-21
申请号：US13331007
申请日：2011-12-20
申请人： Matthew Shaw , Alan D. Gustafson
发明人： Matthew Shaw , Alan D. Gustafson
IPC分类号： B60D1/02 , B60D1/60
CPC分类号： B60D1/02 , B60D1/28 , B60D1/60
摘要： In an example embodiment, an automatic engaging drawbar pin retention device includes a biased locking plate configured to retain a drawbar pin within a drawbar bore. The locking plate may be movably coupled to a drawbar clevis between a pin-lock to at least partly cover the bore and prevent removal of the drawbar pin and a pin-unlock condition.
摘要翻译：在示例性实施例中，自动接合拉杆销保持装置包括被配置为将牵引杆销保持在牵引杆孔内的偏置锁定板。锁定板可以可移动地联接到销闩之间的拉杆U形夹，以至少部分地覆盖孔，并且防止牵引杆销的移除和销的解锁状态。

6. 发明申请

US20070059672A1 Nutrition tracking systems and methods 审中-公开
标题翻译：营养跟踪系统和方法
公开(公告)号：US20070059672A1
公开(公告)日：2007-03-15
申请号：US11224468
申请日：2005-09-12
申请人： Matthew Shaw
发明人： Matthew Shaw
IPC分类号： G09B19/00 , G06F1/16
CPC分类号： G09B19/0092
摘要： A method for a user to track nutrition information includes: scanning a plurality of nutrition codes corresponding to a plurality of respective food items via a scanning device, wherein each of said plurality of nutrition codes corresponds to nutrition information for each of said plurality of respective food items; consuming substantially all of said plurality of respective food items; and viewing aggregated nutrition information corresponding to said plurality of respective food items.
摘要翻译：用于跟踪营养信息的方法包括：通过扫描装置扫描对应于多个相应食物的多个营养代码，其中所述多个营养代码中的每一个对应于所述多个相应食物中的每一个的营养信息物品基本上消耗所述多个相应的食品; 以及查看与所述多个相应食品相对应的聚合营养信息。

7. 发明申请

US20060015841A1 Control on demand data center service configurations 审中-公开
标题翻译：控制按需数据中心服务配置
公开(公告)号：US20060015841A1
公开(公告)日：2006-01-19
申请号：US10880863
申请日：2004-06-30
申请人： Ellis Bishop , Randy Johnson , Tedrick Northway , H. Rinckel , Matthew Shaw , Clea Zolotow
发明人： Ellis Bishop , Randy Johnson , Tedrick Northway , H. Rinckel , Matthew Shaw , Clea Zolotow
IPC分类号： G06F9/44
CPC分类号： G06F9/5077
摘要： An example of a solution provided here comprises: providing a shared platform that is prepared to accept an incoming customer; for the incoming customer (a) planning a configuration of hardware, software, and network components; (b) designing the configuration; and (c) utilizing at least one configuration management control point; accepting the incoming customer, among multiple customers, on the shared platform; sharing hardware and software, among the multiple customers; and maintaining information concerning the shared platform.
摘要翻译：这里提供的解决方案的示例包括：提供准备接受传入客户的共享平台; 对于传入的客户（a）规划硬件，软件和网络组件的配置; （b）设计配置; 和（c）利用至少一个配置管理控制点; 在共享平台上接受多个客户中的传入客户; 共享硬件和软件，在多个客户之间; 并维护有关共享平台的信息。

8. 发明申请

US20050259683A1 Control service capacity 审中-公开
标题翻译：控制服务能力
公开(公告)号：US20050259683A1
公开(公告)日：2005-11-24
申请号：US10825025
申请日：2004-04-15
申请人： Ellis Bishop , Randy Johnson , Tedrick Northway , H. Rinckel , Matthew Shaw , Clea Zolotow
发明人： Ellis Bishop , Randy Johnson , Tedrick Northway , H. Rinckel , Matthew Shaw , Clea Zolotow
IPC分类号： G06F15/173 , H04J3/16 , H04J3/22 , H04L12/24
CPC分类号： H04L41/0896 , H04L41/5009
摘要： A system and method is disclosed for managing information technology resources to provide processing capacity to multiple customers with varying requirements in a shared computing environment. The inventive process comprises producing and maintaining a capacity plan that allocates capacity resources, handling requests for additional capacity resources, and analyzing requests for additional capacity resources to identify issues that should be resolved in future allocations.
摘要翻译：公开了一种用于管理信息技术资源以在共享计算环境中对具有不同需求的多个客户提供处理能力的系统和方法。本发明的过程包括生成和维护分配能力资源的容量计划，处理对额外容量资源的请求，以及分析对额外容量资源的请求，以确定将来分配中应该解决的问题。

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